Estradiol loaded PLGA nanoparticles for oral administration: Effect of polymer molecular weight and copolymer composition on release behavior in vitro and in vivo

Journal of Controlled Release

Volumn 119, Issue 1, 2007, Pages 77-85

  Mittal, G ^a   Sahana, D K ^a   Bhardwaj, V ^a   Ravi Kumar, M N V ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Biocompatible; Biodegradable; Copolymer; Molecular weight; Nanoparticles; Oral delivery

Indexed keywords

BIOAVAILABILITY; DRUG RELEASE; ESTRADIOL; INFLAMMATORY RESPONSE; LACTIDES;

COPOLYMERS; EMULSIONS; HORMONES; MOLECULAR WEIGHT; NANOPARTICLES; PARTICLE SIZE;

DRUG DELIVERY;

COPOLYMER; DIDODECYLDIMETHYL AMMONIUM BROMIDE; ESTRADIOL; NANOPARTICLE; POLYGLACTIN; POLYMER; STABILIZING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG RELEASE; EMULSION; EVAPORATION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; DELAYED-ACTION PREPARATIONS; ESTRADIOL; LACTIC ACID; MALE; MOLECULAR WEIGHT; NANOPARTICLES; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34147150618     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.01.016     Document Type: Article

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