Nanomedicine: the future for advancing medicine and neuroscience

Nanomedicine

Volumn 7, Issue 8, 2012, Pages 1113-1116

  Tosi, Giovanni ^a   Ruozi, Barbara ^a   Belletti, Daniela ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

nanomedicine; nanoparticles; neuro disorders; targeted medicine

Indexed keywords

CONTRAST MEDIUM; DENDRIMER; DRUG CARRIER; FERUCARBOTRAN; FERUMOXSIL; GOLD; INSULIN; IRON; LIGAND; LIPOSOME; LOPERAMIDE; METAL; NANOCARRIER; NANOPARTICLE; POLYGLACTIN; POLYMER; RHODAMINE 123; SOLID LIPID NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE; SYNTHETIC PEPTIDE; THIAMINE; TRANSFERRIN;

ALZHEIMER DISEASE; BIOENGINEERING; BLOOD BRAIN BARRIER; BRAIN CELL; BRAIN TUMOR; CENTRAL NERVOUS SYSTEM; CONTRAST ENHANCEMENT; DEGENERATIVE DISEASE; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TARGETING; EXOCYTOSIS; GLIA CELL; HUMAN; HUNTINGTON CHOREA; MACROMOLECULE; MICELLE; MULTIPLE SCLEROSIS; NANOMEDICINE; NANOTECHNOLOGY; NERVE CELL; NEUROLOGIC DISEASE; NEUROSCIENCE; PARKINSON DISEASE; PARTICLE SIZE; PERSONALIZED MEDICINE; PRIORITY JOURNAL; REVIEW; TARGET CELL; TRANSCYTOSIS;

CENTRAL NERVOUS SYSTEM; DRUG DELIVERY SYSTEMS; HUMANS; INDIVIDUALIZED MEDICINE; NANOMEDICINE; NERVOUS SYSTEM DISEASES; NEUROSCIENCES;

EID: 84868127411     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.90     Document Type: Review

References (24)

1. Wagner V, Dullaart A, Bock AK et al. The emerging nanomedicine landscape. Nat. Biotechnol. 24, 1211-1217 (2006). (Pubitemid 44564760)
2. Tosi G, Costantino L, Ruozi B et al. Polymeric nanoparticles for the drug delivery to the central nervous system. Expert Opin. Drug Deliv. 5, 155-174 (2008). (Pubitemid 351308309)
3. Sahay G, Alakova DY, Kabanov AV. Endocytosis of nanomedicines. J. Control. Release 145, 182-195 (2010).
4. Costantino L, Tosi G, Ruozi B et al. Colloidal systems for CNS drug delivery. Prog. Brain Res. 180, 35-69 (2009).
5. Palumbo FS, Pitar G, Mandracchia D et al. New graft copolymers of hyaluronic acid and polylactic acid: synthesis and characterization. Carbohydr. Polym. 66, 379-385 (2006). (Pubitemid 44585067)
6. Pitarresi G, Tripodo G, Triolo D et al. Inulin vinyl sulfone derivative crosslinked with bis-amino PEG: new materials for biomedical applications. J. Drug Del. Sci. 19, 419- 423 (2009).
7. Vyas SP, Singh A, Sihorkar V. Ligand-receptor-mediated drug delivery: an emerging paradigm in cellular drug targeting. Crit. Rev. Ther. Drug Carr. Syst. 18, 1-76 (2001). (Pubitemid 32319397)
8. Newton HB. Advances in strategies to improve drug delivery to brain tumors. Expert Rev. Neurother. 6(10), 1495-1509 (2006). (Pubitemid 44690919)
9. Gabathuler R. Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol. Dis. 37, 48-57 (2010).
10. Kreuter J. Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J. Nanosci. Nanotechnol. 4, 484-488 (2004). (Pubitemid 39387399)
11. Pardridge WM. Drug and gene targeting to the brain with molecular Trojan horses. Nat. Rev. Drug Discov. 1, 131-139 (2002). (Pubitemid 41646520)
12. Ji B, Maeda J, Higuchi M et al. Pharmacokinetics and brain uptake of lactoferrin in rats. Life Sci. 78, 851-855 (2006). (Pubitemid 43082309)
13. Scherrmann JM, Temsamani J. The use of Pep: transvectors for the delivery of drugs into the central nervous system. Int. Congr. Ser. 1277, 199-211 (2005). (Pubitemid 43715318)
14. Gabathuler R, Arthur G, Kennard M et al. Development of a potential protein vector (NeuroTrans) to deliver drugs across the blood-brain barrier. Int. Congr. Ser. 1277, 171-184 (2005). (Pubitemid 43693327)
15. Chakraborty C, Sarkar B, Hsu CH et al. Future prospects of nanoparticles on brain targeted drug delivery. J. Neurooncol. 93, 285-286 (2009).
16. Umezawa F, Eto Y. Liposomes targeting to mouse brain: mannose as a recognition marker. Biochem. Biophys. Res. Comm. 153, 1038-1044 (1988).
17. Wu D, Pardridge WM. Blood-brain barrier transport of reduced folic acid. Pharm. Res. 16, 415-419 (1999). (Pubitemid 29162100)
18. Costantino L, Gandolfi F, Tosi G et al. Peptide-derivatized biodegradable nanoparticles able to cross the blood-brain barrier. J. Control. Release 108, 84-96 (2005). (Pubitemid 41476677)
19. Tosi G, Fano AF, Bondioli L et al. Investigation on mechanisms of glycopeptides nanoparticles for drug delivery across the blood-brain barrier. Nanomedicine (Lond.) 6(3), 423-436 (2011).
20. Grabrucker AM, Garner CC, Boeckers TM et al. Development of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidences. PLoS ONE 6, E17851 (2011).
21. Tosi G, Costantino L, Rivasi F et al. In vivo experiments with peptide derivatized nanoparticles loaded with loperamide and rhodamine 123. J. Control. Release 122, 1-9 (2007). (Pubitemid 47284547)
22. Tosi G, Vergoni AV, Ruozi B et al. Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: in vivo pharmacological evidence and biodistribution. J. Control. Release 145, 49-57 (2010).
23. Tosi G, Bondioli L, Ruozi B et al. NIR-labeled nanoparticles engineered for brain targeting: in vivo optical imaging application and fluorescent microscopy evidences. J. Neuron Trasm. 118, 145-153 (2011).
24. Vergoni AV, Tosi G, Tacchi R et al. Nanoparticles as drug delivery agents specific for CNS: in vivo biodistribution. Nanomedicine 5, 369-377 (2009).