Activation of antigen-specific T cell-responses by mannan-decorated PLGA nanoparticles

Pharmaceutical Research

Volumn 28, Issue 9, 2011, Pages 2288-2301

  Hamdy, Samar ^a   Haddadi, Azita ^b   Shayeganpour, Anooshirvan ^a   Samuel, John ^a   Lavasanifar, Afsaneh ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Dendritic cells; Mannan; PLGA; Targeting; Vaccine

Indexed keywords

DENDRITIC CELL VACCINE; GAMMA INTERFERON; INTERLEUKIN 2; MANNAN; NANOPARTICLE; OVALBUMIN; POLYGLACTIN;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; IMMUNIZATION; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANIMALS; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; DRUG CARRIERS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; LACTIC ACID; LECTINS, C-TYPE; LYMPH NODES; LYMPHOCYTE ACTIVATION; MALE; MANNANS; MANNOSE-BINDING LECTINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; POLYGLYCOLIC ACID; RECEPTORS, CELL SURFACE; SPLEEN; T-LYMPHOCYTES; VACCINES;

EID: 80054754759     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0459-9     Document Type: Article

References (37)

1. Keler T, Ramakrishna V, Fanger MW. Mannose receptortargeted vaccines. Expert Opin Biol Ther. 2004;4(12):1953-62.
2. White KL, Rades T, Furneaux RH, Tyler PC, Hook S. Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. J Pharm Pharmacol. 2006;58(6):729-37. (Pubitemid 43836160)
3. Espuelas S, Thumann C, Heurtault B, Schuber F, Frisch B. Influence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes. Bioconjug Chem. 2008;19(12):2385-93.
4. Joralemon MJ, Murthy KS, Remsen EE, Becker ML, Wooley KL. Synthesis, characterization, and bioavailability of mannosylated shell cross-linked nanoparticles. Biomacromolecules. 2004;5(3):903-13. (Pubitemid 38702264)
5. Jain S, Vyas SP. Mannosylated niosomes as adjuvant-carrier system for oral mucosal immunization. J Liposome Res. 2006;16(4):331-45. (Pubitemid 44949884)
6. Vinogradov E, Petersen B, Bock K. Structural analysis of the intact polysaccharide mannan from Saccharomyces cerevisiae yeast using 1 H and 13 C NMR spectroscopy at 750 MHz. Carbohydr Res. 1998;307(1-2):177-83. (Pubitemid 28282862)
7. Tada H, Nemo to E, Shimauchi H, Watanabe T, Mikami T, Matsumoto T, et al. Saccharomyces cerevisiae-and Candida albicans-derived mannan induced production of tumor necrosis factor alpha by human monocytes in a CD 14-and Toll-like receptor 4-dependent manner. Microbiol Immunol. 2002;46(7):503-12. (Pubitemid 34831216)
8. Ghotbi Z, Haddadi A, Hamdy S, Hung RW, Samuel J, Lavasanifar A. Active targeting of dendritic cells with mannandecorated PLGA nanoparticles. J Drug Target. 2010, Jun. 30.
9. Elamanchili P, Diwan M, Cao M, Samuel J. Characterization of poly (D, L-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells. Vaccine. 2004;22(19):2406-12. (Pubitemid 38757337)
10. Lutsiak ME, Kwon GS, Samuel J. Biodegradable nanoparticle delivery of a Th2-biased peptide for induction of Th1 immune responses. J Pharm Pharmacol. 2006;58(6):739-47. (Pubitemid 43836161)
11. Diwan M, Elamanchili P, Lane H, Gainer A, Samuel J. Biodegradable nanoparticle mediated antigen delivery to human cord blood derived dendritic cells for induction of primary T cell responses. J Drug Target. 2003;11(8-10):495-507. (Pubitemid 38519159)
12. Hamdy S, Molavi O, Ma Z, Haddadi A, Alshamsan A, Gobti Z, et al. Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cellmediated anti-tumor immunity. Vaccine. 2008;26(39):5046-57.
13. Elamanchili P, Lutsiak CM, Hamdy S, Diwan M, Samuel J. "'Pathogen-mimicking" nanoparticles for vaccine delivery to dendritic cells. J Immunother. 2007;30(4):378-95. (Pubitemid 46684428)
14. Fischer S, Schlosser E, Mueller M, Csaba N, Merkle HP, Groettrup M, et al. Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response. J Drug Target. 2009 Jul. 10.
15. Schlosser E, Mueller M, Fischer S, Basta S, Busch DH, Gander B, et al. TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses. Vaccine. 2008;26(13):1626-37.
16. Hamdy S, Elamanchili P, Alshamsan A, Molavi O, Satou T, Samuel J. Enhanced antigen-specific primary CD4+ and CD8+ responses by codelivery of ovalbumin and toll-like receptor ligand monophosphoryl lipid A in poly (D, L-lactic-co-glycolic acid) nanoparticles. J Biomed Mater Res A. 2007;81(3):652-62. (Pubitemid 46786896)
17. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods. 1999;223(1):77-92. (Pubitemid 29096240)
18. Gamvrellis A, Leong D, Hanley JC, Xiang SD, Mottram P, Plebanski M. Vaccines that facilitate antigen entry into dendritic cells. Immunol Cell Biol. 2004;82(5):506-16. (Pubitemid 39421060)
19. Heuking S, Adam-Malpel S, Sublet E, Iannitelli A, Stefano A, Borchard G. Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers. J Drug Target. 2009;17(8):662-70.
20. Wischke C, Zimmermann J, Wessinger B, Schendler A, Borchert HH, Peters JH, et al. Poly (I:C) coated PLGA microparticles induce dendritic cell maturation. Int J Pharm. 2009;365(1-2):61-8.
21. Fischer S, Schlosser E, Mueller M, Csaba N, Merkle HP, Groettrup M, et al. Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response. J Drug Target. 2009;17(8):652-61.
22. San Roman B, Irache JM, Gomez S, Tsapis N, Gamazo C, Espuelas MS. Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology. Eur J Pharm Biopharm. 2008;70(1):98-108.
23. Kaiser-Schulz G, Heit A, Quintanilla-Martinez L, Hammerschmidt F, Hess S, Jennen L, et al. Polylactide-coglycolide microspheres co-encapsulating recombinant tandem prion protein with CpG-oligonucleotide break self-tolerance to prion protein in wildtype mice and induce CD4 and CD8 T cell responses. J Immunol. 2007;179(5):2797-807.
24. Martinez Gomez JM, Fischer S, Csaba N, Kundig TM, Merkle HP, Gander B, et al. A protective allergy vaccine based on CpG-and protamine-containing PLGA microparticles. Pharm Res. 2007;24(10):1927-35. (Pubitemid 47389249)
25. Cruz LJ, Tacken PJ, Fokkink R, Joosten B, Stuart MC, Albericio F, et al. Targeted PLGA nano-but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. J Control Release. Feb. 13.
26. Kammona O, Alexopoulos HA, Karakosta P, Kotti K, Karageorgiou V, Kiparissides C. Nanocarrier aided nasal vaccination: an experimental and computational approach. Ind Eng Chem Res. 2011;50(2):590-601.
27. Wattendorf U, Coullerez G, Voros J, Textor M, Merkle HP. Mannose-based molecular patterns on stealth microspheres for receptor-specific targeting of human antigen-presenting cells. Langmuir. 2008;24(20):11790-802.
28. Lees CJ, Apostolopoulos V, Acres B, Ong CS, Popovski V, McKenzie IF. The effect of T1 and T2 cytokines on the cytotoxic T cell response to mannan-MUC1. Cancer Immunol Immunother. 2000;48(11):644-52. (Pubitemid 30064667)
29. Lees CJ, Apostolopoulos V, McKenzie IF. Cytokine production from murine CD4 and CD8 cells after mannan-MUC1 immunization. J Interferon Cytokine Res. 1999;19(12):1373-9. (Pubitemid 30032939)
30. Apostolopoulos V, Pietersz GA, Gordon S, Martinez-Pomares L, McKenzie IF. Aldehyde-mannan antigen complexes target the MHC class I antigen-presentation pathway. Eur J Immunol. 2000;30(6):1714-23. (Pubitemid 30342815)
31. Newman KD, Kwon GS, Miller GG, Chlumecky V, Samuel J. Cytoplasmic delivery of a macromolecular fluorescent probe by poly (d, l-lactic-co-glycolic acid) microspheres. J Biomed Mater Res. 2000;50(4):591-7. (Pubitemid 30225386)
32. Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA. In vivo targeting of dendritic cells in lymph nodes with poly (propylene sulfide) nanoparticles. J Control Release. 2006;112(1):26-34.
33. Reece JC, Vardaxis NJ, Marshall JA, Crowe SM, Cameron PU. Uptake of HIV and latex particles by fresh and cultured dendritic cells and monocytes. Immunol Cell Biol. 2001;79(3):255-63. (Pubitemid 32522174)
34. Grossmann C, Tenbusch M, Nchinda G, Temchura V, Nabi G, Stone GW, et al. Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands. BMC Immunol. 2009;10:43.
35. Ferwerda G, Meyer-Wentrup F, Kullberg BJ, Netea MG, Adema GJ. Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages. Cell Microbiol. 2008;10(10):2058-66.
36. Dennehy KM, Ferwerda G, Faro-Trindade I, Pyz E, Willment JA, Taylor PR, et al. Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol. 2008;38(2):500-6.
37. Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med. 2003;197(9):1107-17. (Pubitemid 36570066)