메뉴 건너뛰기




Volumn 5, Issue 4, 2013, Pages 717-742

Phylogenetic study of polyketide synthases and nonribosomal peptide synthetases involved in the biosynthesis of mycotoxins

Author keywords

ketosynthase; Acyl transferase; Adenylation; Condensation; Non ribosomal peptide synthetase; Phylogenies; Polyketide synthase; Secondary metabolites

Indexed keywords

ACYLTRANSFERASE; BETA KETOSYNTHASE; MYCOTOXIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; OCHRATOXIN; POLYKETIDE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

EID: 84877308775     PISSN: 20726651     EISSN: None     Source Type: Journal    
DOI: 10.3390/toxins5040717     Document Type: Article
Times cited : (74)

References (98)
  • 1
    • 9244234513 scopus 로고    scopus 로고
    • Biosynthesis of nonribosomal peptides
    • Finking, R.; Marahiel, M.A. Biosynthesis of nonribosomal peptides. Annu. Rev. Microbiol. 2004, 58, 453-488.
    • (2004) Annu. Rev. Microbiol , vol.58 , pp. 453-488
    • Finking, R.1    Marahiel, M.A.2
  • 2
    • 67650308266 scopus 로고    scopus 로고
    • Hidden biosynthetic treasures brought to light
    • Hertweck, C. Hidden biosynthetic treasures brought to light. Nat. Chem. Biol. 2009, 5, 450-452.
    • (2009) Nat. Chem. Biol , vol.5 , pp. 450-452
    • Hertweck, C.1
  • 3
    • 33748631825 scopus 로고    scopus 로고
    • Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: Logic, machinery, and mechanisms
    • Fischbach, M.A.; Walsh, C.T. Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: Logic, machinery, and mechanisms. Chem. Rev. 2006, 106, 3468-3496.
    • (2006) Chem. Rev , vol.106 , pp. 3468-3496
    • Fischbach, M.A.1    Walsh, C.T.2
  • 4
    • 0035023450 scopus 로고    scopus 로고
    • Multimodular biocatalysts for natural product assembly
    • Schwarzer, D.; Marahiel, M.A. Multimodular biocatalysts for natural product assembly. Naturwissenschaften 2001, 88, 93-101.
    • (2001) Naturwissenschaften , vol.88 , pp. 93-101
    • Schwarzer, D.1    Marahiel, M.A.2
  • 5
    • 0034887171 scopus 로고    scopus 로고
    • Polyketide biosynthesis: A millennium review
    • Staunton, J.; Weissman, K.J. Polyketide biosynthesis: A millennium review. Nat. Prod. Rep. 2001, 18, 380-416.
    • (2001) Nat. Prod. Rep , vol.18 , pp. 380-416
    • Staunton, J.1    Weissman, K.J.2
  • 6
    • 67649234111 scopus 로고    scopus 로고
    • Complex enzymes in microbial natural product biosynthesis, part B: Polyketides, Aminocoumarins and Carbohydrates
    • Chapter3: Fungal Type I Polyketide Synthases
    • Cox, R.J.; Simpson, T.J. Complex enzymes in microbial natural product biosynthesis, part B: Polyketides, aminocoumarins and carbohydrates. Chapter3: Fungal type I polyketide synthases. Methods Enzymol. 2009, 459, 49-98.
    • (2009) Methods Enzymol , vol.459 , pp. 49-98
    • Cox, R.J.1    Simpson, T.J.2
  • 7
    • 0036774667 scopus 로고    scopus 로고
    • Modification of post-PKS tailoring steps through combinatorial biosynthesis
    • Rix, U.; Fischer, C.; Remsing, L.L.; Rohr, J. Modification of post-PKS tailoring steps through combinatorial biosynthesis. Nat. Prod. Rep. 2002, 19, 542-580.
    • (2002) Nat. Prod. Rep , vol.19 , pp. 542-580
    • Rix, U.1    Fischer, C.2    Remsing, L.L.3    Rohr, J.4
  • 8
    • 64249111051 scopus 로고    scopus 로고
    • Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides
    • Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes
    • Meier, J.L.; Burkart, M.D. Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides. Chapter 9. Synthetic probes for polyketide and nonribosomal peptide biosynthetic enzymes. Methods Enzymol. 2009, 458, 219-254.
    • (2009) Methods Enzymol , vol.458 , pp. 219-254
    • Meier, J.L.1    Burkart, M.D.2
  • 9
    • 46049092624 scopus 로고    scopus 로고
    • Evolution and Taxonomic Distribution of Nonribosomal Peptide and Polyketide Synthases
    • Amoutzias, G.D.; Van de Peer, Y.; Mossialos, D. Evolution and taxonomic distribution of nonribosomal peptide and polyketide synthases. Future Microbiol. 2008, 3, 361-370.
    • (2008) Future Microbiol , vol.3 , pp. 361-370
    • Amoutzias, G.D.1    Van de Peer, Y.2    Mossialos, D.3
  • 10
    • 33947303415 scopus 로고    scopus 로고
    • Non-linear Enzymatic Logic In Natural Product Modular Mega-synthases and -synthetases
    • Haynes, S.W.; Challis, G.L. Non-linear enzymatic logic in natural product modular mega-synthases and -synthetases. Curr. Opin. Drug. Discov. Devel. 2007, 10, 203-218.
    • (2007) Curr. Opin. Drug. Discov. Devel , vol.10 , pp. 203-218
    • Haynes, S.W.1    Challis, G.L.2
  • 11
    • 33947694781 scopus 로고    scopus 로고
    • Natural products of filamentous fungi: Enzymes, genes, and their regulation
    • Hoffmeister, D.; Keller, N.P. Natural products of filamentous fungi: Enzymes, genes, and their regulation. Nat. Prod. Rep. 2007, 24, 393-416.
    • (2007) Nat. Prod. Rep , vol.24 , pp. 393-416
    • Hoffmeister, D.1    Keller, N.P.2
  • 12
    • 34547119075 scopus 로고    scopus 로고
    • Macrocyclization Strategies In Polyketide and Nonribosomal Peptide Biosynthesis
    • Kopp, F.; Marahiel, M.A. Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis. Nat. Prod. Rep. 2007, 24, 735-749.
    • (2007) Nat. Prod. Rep , vol.24 , pp. 735-749
    • Kopp, F.1    Marahiel, M.A.2
  • 13
    • 48749083335 scopus 로고    scopus 로고
    • Crystal structure of the termination module of a nonribosomal peptide synthetase
    • Tanovic, A.; Samel, S.A.; Essen, L.O.; Marahiel, M.A. Crystal structure of the termination module of a nonribosomal peptide synthetase. Science 2008, 321, 659-663.
    • (2008) Science , vol.321 , pp. 659-663
    • Tanovic, A.1    Samel, S.A.2    Essen, L.O.3    Marahiel, M.A.4
  • 14
    • 63849314526 scopus 로고    scopus 로고
    • A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans
    • Von Döhren, H. A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans. Fungal Genet. Biol. 2009, 46, S45-S52.
    • (2009) Fungal Genet. Biol , vol.46
    • Von Döhren, H.1
  • 15
  • 16
    • 78650200742 scopus 로고    scopus 로고
    • Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo
    • Evans, B.S.; Robinson, S.J.; Kelleher, N.L. Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo. Fungal Genet. Biol. 2011, 48, 49-61.
    • (2011) Fungal Genet. Biol , vol.48 , pp. 49-61
    • Evans, B.S.1    Robinson, S.J.2    Kelleher, N.L.3
  • 17
    • 77950949876 scopus 로고    scopus 로고
    • Non-ribosomal peptide synthetases of fungi
    • 1st ed, Anke, T., Weber, D., Eds, Springer: Heidelberg, Germany
    • Eisfeld, K. Non-ribosomal peptide synthetases of fungi. In Physiology and Genetics: Selected Basic and Applied Aspects, 1st ed.; Anke, T., Weber, D., Eds.; Springer: Heidelberg, Germany, 2009; Volume 15, pp. 305-330.
    • (2009) In Physiology and Genetics: Selected Basic and Applied Aspects , vol.15 , pp. 305-330
    • Eisfeld, K.1
  • 18
    • 0034796211 scopus 로고    scopus 로고
    • Hybrid peptide-polyketide natural products: Biosynthesis and prospects toward engineering novel molecules
    • Du, L.; Sánchez, C.; Shen, B. Hybrid peptide-polyketide natural products: Biosynthesis and prospects toward engineering novel molecules. Metab. Eng. 2001, 3, 78-95.
    • (2001) Metab. Eng , vol.3 , pp. 78-95
    • Du, L.1    Sánchez, C.2    Shen, B.3
  • 19
    • 39349109073 scopus 로고    scopus 로고
    • Emerging fusarium-mycotoxins fusaproliferin, beauvericin, enniatins, and moniliformin: A review
    • Jestoi, M. Emerging fusarium-mycotoxins fusaproliferin, beauvericin, enniatins, and moniliformin: A review. Crit. Rev. Food Sci. Nutr. 2008, 48, 21-49.
    • (2008) Crit. Rev. Food Sci. Nutr , vol.48 , pp. 21-49
    • Jestoi, M.1
  • 20
    • 0031079973 scopus 로고    scopus 로고
    • Metabolic pathway gene clusters in filamentous fungi
    • Keller, N.P.; Hohn, T.M. Metabolic pathway gene clusters in filamentous fungi. Fungal Genet. Biol. 1997, 21, 17-29.
    • (1997) Fungal Genet. Biol , vol.21 , pp. 17-29
    • Keller, N.P.1    Hohn, T.M.2
  • 23
    • 22844450779 scopus 로고    scopus 로고
    • Birth of a metabolic gene cluster in yeast by adaptive gene relocation
    • Wong, S.; Wolfe, K.H. Birth of a metabolic gene cluster in yeast by adaptive gene relocation. Nat. Genet. 2005, 37,777-782.
    • (2005) Nat. Genet , vol.37 , pp. 777-782
    • Wong, S.1    Wolfe, K.H.2
  • 24
    • 0033762670 scopus 로고    scopus 로고
    • Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: An hypothesis
    • Walton, J.D. Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: An hypothesis. Fungal Genet. Biol. 2000, 30, 167-171.
    • (2000) Fungal Genet. Biol , vol.30 , pp. 167-171
    • Walton, J.D.1
  • 25
    • 44649170477 scopus 로고    scopus 로고
    • Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi
    • Khaldi, N.; Collemare, J.; Lebrun, M.H.; Wolfe, K.H. Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi. Genome Biol. 2008, 9, R18.
    • (2008) Genome Biol , vol.9
    • Khaldi, N.1    Collemare, J.2    Lebrun, M.H.3    Wolfe, K.H.4
  • 26
    • 30544434099 scopus 로고    scopus 로고
    • Fungal secondary metabolism - from biochemistry to genomics
    • Keller, N.P.; Turner, G.; Bennett, J.W. Fungal secondary metabolism - from biochemistry to genomics. Nat. Rev. Microbiol. 2005, 3, 937-947.
    • (2005) Nat. Rev. Microbiol , vol.3 , pp. 937-947
    • Keller, N.P.1    Turner, G.2    Bennett, J.W.3
  • 27
    • 10744231115 scopus 로고    scopus 로고
    • Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles
    • Piel, J.; Höfer, I.; Hui, D. Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles. J. Bacteriol. 2004, 186, 1280-1286.
    • (2004) J. Bacteriol , vol.186 , pp. 1280-1286
    • Piel, J.1    Höfer, I.2    Hui, D.3
  • 28
    • 0038518196 scopus 로고    scopus 로고
    • Phylogenomics: Intersection of evolution and genomics
    • Eisen, J.A.; Fraser, C.M. Phylogenomics: Intersection of evolution and genomics. Science 2003, 300, 1706-1707.
    • (2003) Science , vol.300 , pp. 1706-1707
    • Eisen, J.A.1    Fraser, C.M.2
  • 29
    • 0347994901 scopus 로고    scopus 로고
    • Phylogenomic Analysis of Type I Polyketide Synthase Genes In Pathogenic and Saprobic Ascomycetes
    • Kroken, S.; Glass, N.L.; Taylor, J.W.; Yoder, O.C.; Turgeon, B.G. Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes. Proc. Natl. Acad. Sci. USA 2003, 100, 15670-15675.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15670-15675
    • Kroken, S.1    Glass, N.L.2    Taylor, J.W.3    Yoder, O.C.4    Turgeon, B.G.5
  • 30
    • 84887212800 scopus 로고    scopus 로고
    • Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi
    • Schmitt, I.; Lumbsch, H.T. Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi. PLoS One 2009, 4, e4437.
    • (2009) PLoS One , vol.e4437 , pp. 4
    • Schmitt, I.1    Lumbsch, H.T.2
  • 31
    • 84859078407 scopus 로고    scopus 로고
    • The natural product domain seeker NaPDoS: A phylogeny based bioinformatic tool to classify secondary metabolite gene diversity
    • Ziemert, N.; Podell, S.; Penn, K.; Badger, J.H.; Allen, E.; Jensen, P.R. The natural product domain seeker NaPDoS: A phylogeny based bioinformatic tool to classify secondary metabolite gene diversity. PLoS One 2012, 7, e34064.
    • (2012) PLoS One , vol.e34064 , pp. 7
    • Ziemert, N.1    Podell, S.2    Penn, K.3    Badger, J.H.4    Allen, E.5    Jensen, P.R.6
  • 32
    • 77149168140 scopus 로고    scopus 로고
    • Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships
    • Bushley, K.E.; Turgeon, B.G. Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships. BMC Evol. Biol. 2010, 10, 26.
    • (2010) BMC Evol. Biol , vol.10 , pp. 26
    • Bushley, K.E.1    Turgeon, B.G.2
  • 35
    • 33845291462 scopus 로고    scopus 로고
    • Nonribosomal peptide synthetase (NPS) genes in Fusarium graminearum, F. culmorum and F. pseudograminearium and identification of NPS2 as the producer of ferricrocin
    • Tobiasen, C.; Aahman, J.; Ravnholt, K.S.; Bjerrum, M.J.; Grell, M.N.; Giese, H. Nonribosomal peptide synthetase (NPS) genes in Fusarium graminearum, F. culmorum and F. pseudograminearium and identification of NPS2 as the producer of ferricrocin. Curr. Genet. 2007, 51, 43-58.
    • (2007) Curr. Genet , vol.51 , pp. 43-58
    • Tobiasen, C.1    Aahman, J.2    Ravnholt, K.S.3    Bjerrum, M.J.4    Grell, M.N.5    Giese, H.6
  • 36
    • 0141532923 scopus 로고    scopus 로고
    • Diversity of polyketide synthase gene sequences in Aspergillus species
    • Varga, J.; Rigó, K.; Kocsubé, S.; Farkas, B.; Pál, K. Diversity of polyketide synthase gene sequences in Aspergillus species. Res. Microbiol. 2003, 154, 593-600.
    • (2003) Res. Microbiol , vol.154 , pp. 593-600
    • Varga, J.1    Rigó, K.2    Kocsubé, S.3    Farkas, B.4    Pál, K.5
  • 39
    • 46649115560 scopus 로고    scopus 로고
    • Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical Starter Unit Effect
    • Crawford, J.M.; Vagstad, A.L.; Whitworth, K.P.; Townsend, C.A. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "Starter Unit Effect". ChemBioChem 2008, 9, 1019-1023.
    • (2008) ChemBioChem , vol.9 , pp. 1019-1023
    • Crawford, J.M.1    Vagstad, A.L.2    Whitworth, K.P.3    Townsend, C.A.4
  • 40
    • 67650273044 scopus 로고    scopus 로고
    • Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster
    • Cary, J.W.; Ehrlich, K.C.; Beltz, S.B.; Harris-Coward, P.; Klich, M.A. Characterization of the Aspergillus ochraceoroseus aflatoxin/sterigmatocystin biosynthetic gene cluster. Mycologia 2009, 101, 352-362.
    • (2009) Mycologia , vol.101 , pp. 352-362
    • Cary, J.W.1    Ehrlich, K.C.2    Beltz, S.B.3    Harris-Coward, P.4    Klich, M.A.5
  • 41
    • 33646459628 scopus 로고    scopus 로고
    • A polyketide synthase gene required for biosynthesis of the aflatoxin-like toxin, dothistromin
    • Bradshaw, R.E.; Jin, H.; Morgan, B.S.; Schwelm, A.; Teddy, O.R.; Young, C.A.; Zhang, S. A polyketide synthase gene required for biosynthesis of the aflatoxin-like toxin, dothistromin. Mycopathologia 2006, 161, 283-294.
    • (2006) Mycopathologia , vol.161 , pp. 283-294
    • Bradshaw, R.E.1    Jin, H.2    Morgan, B.S.3    Schwelm, A.4    Teddy, O.R.5    Young, C.A.6    Zhang, S.7
  • 44
    • 17644387189 scopus 로고    scopus 로고
    • The CTB1 gene encoding a fungal polyketide synthase is required for cercosporin biosynthesis and fungal virulence of Cercospora nicotianae
    • Choquer, M.; Dekkers, K.L.; Chen, H.Q.; Cao, L.; Ueng, P.P.; Daub, M.E.; Chung, K.R. The CTB1 gene encoding a fungal polyketide synthase is required for cercosporin biosynthesis and fungal virulence of Cercospora nicotianae. Mol. Plant Microbe Interact. 2005, 18, 468-476.
    • (2005) Mol. Plant Microbe Interact , vol.18 , pp. 468-476
    • Choquer, M.1    Dekkers, K.L.2    Chen, H.Q.3    Cao, L.4    Ueng, P.P.5    Daub, M.E.6    Chung, K.R.7
  • 45
    • 78649940975 scopus 로고    scopus 로고
    • Aspergillus Genomics and DHN-melanin Conidial Pigmentation
    • Varga, J., Samson, R.A., Eds.; Wageningen Academic Publishers: Wageningen, The Netherlands
    • Baker, S. Aspergillus Genomics and DHN-melanin Conidial Pigmentation. In Aspergillus in the Genomic Era; Varga, J., Samson, R.A., Eds.; Wageningen Academic Publishers: Wageningen, The Netherlands, 2008; pp. 73-82.
    • In Aspergillus in the Genomic Era , vol.2008 , pp. 73-82
    • Baker, S.1
  • 46
    • 27944479301 scopus 로고    scopus 로고
    • Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae
    • Kim, Y.T.; Lee, Y.R.; Jin, J.; Han, K.H.; Kim, H.; Kim, J.C.; Lee, T.; Yun, S.H.; Lee, Y.W. Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae. Mol. Microbiol. 2005, 58, 1102-1113.
    • (2005) Mol. Microbiol , vol.58 , pp. 1102-1113
    • Kim, Y.T.1    Lee, Y.R.2    Jin, J.3    Han, K.H.4    Kim, H.5    Kim, J.C.6    Lee, T.7    Yun, S.H.8    Lee, Y.W.9
  • 47
    • 33644945871 scopus 로고    scopus 로고
    • Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae
    • Gaffoor, I.; Trail, F. Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae. Appl. Environ. Microbiol. 2006, 72, 1793-1799.
    • (2006) Appl. Environ. Microbiol , vol.72 , pp. 1793-1799
    • Gaffoor, I.1    Trail, F.2
  • 48
    • 31644438873 scopus 로고    scopus 로고
    • Two polyketide synthase-encoding genes are required for biosynthesis of the polyketide virulence factor, T-toxin, by Cochliobolus heterostrophus
    • Baker, S.E.; Kroken, S.; Inderbitzin, P.; Asvarak, T.; Li, B.Y.; Shi, L.; Yoder, O.C.; Turgeon, B.G. Two polyketide synthase-encoding genes are required for biosynthesis of the polyketide virulence factor, T-toxin, by Cochliobolus heterostrophus. Mol. Plant Microbe Interact. 2006, 19, 139-149.
    • (2006) Mol. Plant Microbe Interact , vol.19 , pp. 139-149
    • Baker, S.E.1    Kroken, S.2    Inderbitzin, P.3    Asvarak, T.4    Li, B.Y.5    Shi, L.6    Yoder, O.C.7    Turgeon, B.G.8
  • 49
    • 0031775204 scopus 로고    scopus 로고
    • REMI-induced mutants of Mycosphaerella zeae-maydis lacking the polyketide PM-toxin are deficient in pathogenesis to corn
    • Yun, S.H.; Turgeon, B.G.; Yoder, O.C. REMI-induced mutants of Mycosphaerella zeae-maydis lacking the polyketide PM-toxin are deficient in pathogenesis to corn. Physiol. Mol. Plant P. 1998, 52, 53-66.
    • (1998) Physiol. Mol. Plant P , vol.52 , pp. 53-66
    • Yun, S.H.1    Turgeon, B.G.2    Yoder, O.C.3
  • 50
    • 84863701287 scopus 로고    scopus 로고
    • Identification of a polyketide synthase required for alternariol (aoh) and alternariol-9-methyl ether (ame) formation in Alternaria alternata
    • Saha, D.; Fetzner, R.; Burkhardt, B.; Podlech, J.; Metzler, M.; Dang, H.; Lawrence, C.; Fischer, R. Identification of a polyketide synthase required for alternariol (aoh) and alternariol-9-methyl ether (ame) formation in Alternaria alternata. PLoS One 2012, 7, e40564.
    • (2012) PLoS One , vol.e40564 , pp. 7
    • Saha, D.1    Fetzner, R.2    Burkhardt, B.3    Podlech, J.4    Metzler, M.5    Dang, H.6    Lawrence, C.7    Fischer, R.8
  • 51
    • 0033591447 scopus 로고    scopus 로고
    • Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
    • Kennedy, J.; Auclair, K.; Kendrew, S.G.; Park, C.; Vederas, J.C.; Hutchinson, C.R. Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. Science 1999, 284, 1368-1372.
    • (1999) Science , vol.284 , pp. 1368-1372
    • Kennedy, J.1    Auclair, K.2    Kendrew, S.G.3    Park, C.4    Vederas, J.C.5    Hutchinson, C.R.6
  • 52
    • 33751092257 scopus 로고    scopus 로고
    • Biosynthesis of lovastatin analogs with a broadly specific acyltransferase
    • Xie, X.; Watanabe, K.; Wojcicki, W.A.; Wang, C.C.; Tang, Y. Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. Chem. Biol. 2006, 13, 1161-1169.
    • (2006) Chem. Biol , vol.13 , pp. 1161-1169
    • Xie, X.1    Watanabe, K.2    Wojcicki, W.A.3    Wang, C.C.4    Tang, Y.5
  • 53
    • 33747476786 scopus 로고    scopus 로고
    • Detection of new fumonisin mycotoxins and fumonisin-like compounds by reversed-phase high-performance liquid chromatography/electrospray ionization ion trap mass spectrometry
    • Bartók, T.; Szécsi, A.; Szekeres, A.; Mesterházy, A.; Bartók, M. Detection of new fumonisin mycotoxins and fumonisin-like compounds by reversed-phase high-performance liquid chromatography/electrospray ionization ion trap mass spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 2447-2462.
    • (2006) Rapid Commun. Mass Spectrom , vol.20 , pp. 2447-2462
    • Bartók, T.1    Szécsi, A.2    Szekeres, A.3    Mesterházy, A.4    Bartók, M.5
  • 54
    • 0032847692 scopus 로고    scopus 로고
    • A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A
    • Proctor, R.H.; Desjardins, A.E.; Plattner, R.D.; Hohn, T.M. A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A. Fungal Genet. Biol. 1999, 27, 100-112.
    • (1999) Fungal Genet. Biol , vol.27 , pp. 100-112
    • Proctor, R.H.1    Desjardins, A.E.2    Plattner, R.D.3    Hohn, T.M.4
  • 55
    • 33749519986 scopus 로고    scopus 로고
    • Aspergillus niger genomics: Past, present and into the future
    • Baker, S.E. Aspergillus niger genomics: Past, present and into the future. Med. Mycol. 2006, 44, S17-S21.
    • (2006) Med. Mycol , vol.44
    • Baker, S.E.1
  • 61
    • 84979823686 scopus 로고    scopus 로고
    • Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae
    • Chang, P.-K.; Ehrlich, K.C.; Fujii, I. Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. Toxins 2009, 1, 74-99.
    • (2009) Toxins , vol.1 , pp. 74-99
    • Chang, P.-K.1    Ehrlich, K.C.2    Fujii, I.3
  • 62
    • 4644244128 scopus 로고    scopus 로고
    • Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum
    • Song, Z.; Cox, R.J.; Lazarus, C.M.; Simpson, T.J. Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum. ChemBioChem 2004, 5, 1196-1203.
    • (2004) ChemBioChem , vol.5 , pp. 1196-1203
    • Song, Z.1    Cox, R.J.2    Lazarus, C.M.3    Simpson, T.J.4
  • 63
    • 34948842874 scopus 로고    scopus 로고
    • Identification of a hybrid PKS/NRPS required for pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus
    • Maiya, S.; Grundmann, A.; Li, X.; Li, S.M.; Turner, G. Identification of a hybrid PKS/NRPS required for pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus. ChemBioChem 2007, 8, 1736-1743.
    • (2007) ChemBioChem , vol.8 , pp. 1736-1743
    • Maiya, S.1    Grundmann, A.2    Li, X.3    Li, S.M.4    Turner, G.5
  • 64
    • 34547817781 scopus 로고    scopus 로고
    • Molecular basis of cytochalasan biosynthesis in fungi: Gene cluster analysis and evidence for the involvement of a PKS-NRPS hybrid synthase by RNA silencing
    • Schümann, J.; Hertweck, C. Molecular basis of cytochalasan biosynthesis in fungi: Gene cluster analysis and evidence for the involvement of a PKS-NRPS hybrid synthase by RNA silencing. J. Am. Chem. Soc. 2007, 129, 9564-9565.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 9564-9565
    • Schümann, J.1    Hertweck, C.2
  • 65
    • 80555131032 scopus 로고    scopus 로고
    • Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1
    • Qiao, K.; Chooi, Y.H.; Tang, Y. Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1. Metab Eng. 2011, 13, 723-732.
    • (2011) Metab Eng , vol.13 , pp. 723-732
    • Qiao, K.1    Chooi, Y.H.2    Tang, Y.3
  • 67
    • 33645081957 scopus 로고    scopus 로고
    • Cloning and molecular characterization of Penicillium expansum genes upregulated under conditions permissive for patulin biosynthesis
    • White, S.; O'Callaghan, J.; Dobson, A.D. Cloning and molecular characterization of Penicillium expansum genes upregulated under conditions permissive for patulin biosynthesis. FEMS Microbiol. Lett. 2006, 255, 17-26.
    • (2006) FEMS Microbiol. Lett , vol.255 , pp. 17-26
    • White, S.1    O'Callaghan, J.2    Dobson, A.D.3
  • 68
    • 0346882655 scopus 로고    scopus 로고
    • A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus
    • O'Callaghan, J.; Caddick, M.X.; Dobson, A.D. A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus. Microbiology 2003, 149, 3485-3491.
    • (2003) Microbiology , vol.149 , pp. 3485-3491
    • O'Callaghan, J.1    Caddick, M.X.2    Dobson, A.D.3
  • 69
    • 57649158248 scopus 로고    scopus 로고
    • Aspergillus westerdijkiae polyketide synthase gene aoks1 is involved in the biosynthesis of ochratoxin A
    • Bacha, N.; Atoui, A.; Mathieu, F.; Liboz, T.; Lebrihi, A. Aspergillus westerdijkiae polyketide synthase gene aoks1 is involved in the biosynthesis of ochratoxin A. Fungal Genet. Biol. 2009, 46, 77-84.
    • (2009) Fungal Genet. Biol , vol.46 , pp. 77-84
    • Bacha, N.1    Atoui, A.2    Mathieu, F.3    Liboz, T.4    Lebrihi, A.5
  • 70
    • 23044502868 scopus 로고    scopus 로고
    • Cloning a Part of the Ochratoxin a Biosynthetic Gene Cluster of Penicillium Nordicum and Characterization of the Ochratoxin Polyketide Synthase Gene
    • Karolewiez, A.; Geisen, R. Cloning a part of the ochratoxin A biosynthetic gene cluster of Penicillium nordicum and characterization of the ochratoxin polyketide synthase gene. Syst. Appl. Microbiol. 2005, 28, 588-595.
    • (2005) Syst. Appl. Microbiol , vol.28 , pp. 588-595
    • Karolewiez, A.1    Geisen, R.2
  • 71
    • 57649205604 scopus 로고    scopus 로고
    • Characterisation of a pks gene which is expressed during ochratoxin A production by Aspergillus carbonarius
    • Gallo, A.; Perrone, G.; Solfrizzo, M.; Epifani, F.; Abbas, A.; Dobson, A.D.; Mulè, G. Characterisation of a pks gene which is expressed during ochratoxin A production by Aspergillus carbonarius. Int. J. Food Microbiol. 2009, 129, 8-15.
    • (2009) Int. J. Food Microbiol , vol.129 , pp. 8-15
    • Gallo, A.1    Perrone, G.2    Solfrizzo, M.3    Epifani, F.4    Abbas, A.5    Dobson, A.D.6    Mulè, G.7
  • 72
    • 0037373801 scopus 로고    scopus 로고
    • Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis
    • Proctor, R.H.; Brown, D.W.; Plattner, R.D.; Desjardins, A.E. Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis. Fungal Genet. Biol. 2003, 38, 237-249.
    • (2003) Fungal Genet. Biol , vol.38 , pp. 237-249
    • Proctor, R.H.1    Brown, D.W.2    Plattner, R.D.3    Desjardins, A.E.4
  • 73
    • 33846147344 scopus 로고    scopus 로고
    • Deletion analysis of FUM genes involved in tricarballylic ester formation during fumonisin biosynthesis
    • Butchko, R.A.; Plattner, R.D.; Proctor, R.H. Deletion analysis of FUM genes involved in tricarballylic ester formation during fumonisin biosynthesis. J. Agric. Food Chem. 2006, 54, 9398-9404.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 9398-9404
    • Butchko, R.A.1    Plattner, R.D.2    Proctor, R.H.3
  • 74
    • 33644527914 scopus 로고    scopus 로고
    • A bidomain nonribosomal peptide synthetase encoded by FUM14 catalyzes the formation of tricarballylic esters in the biosynthesis of fumonisins
    • Zaleta-Rivera, K.; Xu, C.; Yu, F.; Butchko, R.A.; Proctor, R.H.; Hidalgo-Lara, M.E.; Raza, A.; Dussault, P.H.; Du, L. A bidomain nonribosomal peptide synthetase encoded by FUM14 catalyzes the formation of tricarballylic esters in the biosynthesis of fumonisins. Biochemistry 2006, 45, 2561-2569.
    • (2006) Biochemistry , vol.45 , pp. 2561-2569
    • Zaleta-Rivera, K.1    Xu, C.2    Yu, F.3    Butchko, R.A.4    Proctor, R.H.5    Hidalgo-Lara, M.E.6    Raza, A.7    Dussault, P.H.8    Du, L.9
  • 76
    • 4444376010 scopus 로고    scopus 로고
    • The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans
    • Gardiner, D.M.; Cozijnsen, A.J.; Wilson, L.M.; Pedras, M.S.; Howlett, B.J. The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Mol. Microbiol. 2004, 53, 1307-1318.
    • (2004) Mol. Microbiol , vol.53 , pp. 1307-1318
    • Gardiner, D.M.1    Cozijnsen, A.J.2    Wilson, L.M.3    Pedras, M.S.4    Howlett, B.J.5
  • 77
    • 33746320424 scopus 로고    scopus 로고
    • Nonribosomal peptide biosynthesis: Point mutations and module skipping lead to chemical diversity
    • Wenzel, S.C.; Meiser, P.; Binz, T.M.; Mahmud, T.; Müller, R. Nonribosomal peptide biosynthesis: Point mutations and module skipping lead to chemical diversity. Angew. Chem. Int. Ed. Engl. 2006, 45, 2296-2301.
    • (2006) Angew. Chem. Int. Ed. Engl , vol.45 , pp. 2296-2301
    • Wenzel, S.C.1    Meiser, P.2    Binz, T.M.3    Mahmud, T.4    Müller, R.5
  • 78
    • 0036037587 scopus 로고    scopus 로고
    • Enniatin synthetase is a monomer with extended structure: Evidence For An Intramolecular Reaction Mechanism
    • Glinski, M.; Urbanke, C.; Hornbogen, T.; Zocher, R. Enniatin synthetase is a monomer with extended structure: Evidence for an intramolecular reaction mechanism. Arch. Microbiol. 2002, 178, 267-273.
    • (2002) Arch. Microbiol , vol.178 , pp. 267-273
    • Glinski, M.1    Urbanke, C.2    Hornbogen, T.3    Zocher, R.4
  • 79
    • 0027087171 scopus 로고
    • The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame
    • Scott-Craig, J.S.; Panaccione, D.G.; Pocard, J.A.; Walton, J.D. The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame. J. Biol. Chem. 1992, 267, 26044-26049.
    • (1992) J. Biol. Chem , vol.267 , pp. 26044-26049
    • Scott-Craig, J.S.1    Panaccione, D.G.2    Pocard, J.A.3    Walton, J.D.4
  • 80
    • 84870831090 scopus 로고    scopus 로고
    • New insight into the ochratoxin A biosynthetic pathway through deletion of a nonribosomal peptide synthetase gene in Aspergillus carbonarius
    • Gallo, A.; Bruno, K.S.; Solfrizzo, M.; Perrone, G.; Mulè, G.; Visconti, A.; Baker, S.E. New insight into the ochratoxin A biosynthetic pathway through deletion of a nonribosomal peptide synthetase gene in Aspergillus carbonarius. Appl. Environ. Microbiol. 2012, 78, 8208-8218.
    • (2012) Appl. Environ. Microbiol , vol.78 , pp. 8208-8218
    • Gallo, A.1    Bruno, K.S.2    Solfrizzo, M.3    Perrone, G.4    Mulè, G.5    Visconti, A.6    Baker, S.E.7
  • 81
    • 0346968186 scopus 로고    scopus 로고
    • Molecular cloning and analysis of the ergopeptine assembly system in the ergot fungus Claviceps purpurea
    • Correia, T.; Grammel, N.; Ortel, I.; Keller, U.; Tudzynski, P. Molecular cloning and analysis of the ergopeptine assembly system in the ergot fungus Claviceps purpurea. Chem. Biol. 2003, 10, 1281-1292.
    • (2003) Chem. Biol , vol.10 , pp. 1281-1292
    • Correia, T.1    Grammel, N.2    Ortel, I.3    Keller, U.4    Tudzynski, P.5
  • 82
    • 20444414907 scopus 로고    scopus 로고
    • The ergot alkaloid gene cluster in Claviceps purpurea: Extension of the cluster sequence and intra species evolution
    • Haarmann, T.; Machado, C.; Lübbe, Y.; Correia, T.; Schardl, C.L.; Panaccione, D.G.; Tudzynski, P. The ergot alkaloid gene cluster in Claviceps purpurea: Extension of the cluster sequence and intra species evolution. Phytochemistry 2005, 66, 1312-1320.
    • (2005) Phytochemistry , vol.66 , pp. 1312-1320
    • Haarmann, T.1    Machado, C.2    Lübbe, Y.3    Correia, T.4    Schardl, C.L.5    Panaccione, D.G.6    Tudzynski, P.7
  • 83
    • 0026800606 scopus 로고
    • Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution
    • Aharonowitz, Y.; Cohen, G.; Martin, J.F. Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution. Annu. Rev. Microbiol. 1992, 46, 461-495.
    • (1992) Annu. Rev. Microbiol , vol.46 , pp. 461-495
    • Aharonowitz, Y.1    Cohen, G.2    Martin, J.F.3
  • 84
    • 20444417098 scopus 로고    scopus 로고
    • Evolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors
    • Brakhage, A.A.; Al-Abdallah, Q.; Tüncher, A.; Spröte, P. Evolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors. Phytochemistry 2005, 66, 1200-1210.
    • (2005) Phytochemistry , vol.66 , pp. 1200-1210
    • Brakhage, A.A.1    Al-Abdallah, Q.2    Tüncher, A.3    Spröte, P.4
  • 85
    • 33646386406 scopus 로고    scopus 로고
    • Gene clusters for beta-lactam antibiotics and control of their expression: Why have clusters evolved, and from where did they originate
    • Liras, P.; Martín, J.F. Gene clusters for beta-lactam antibiotics and control of their expression: Why have clusters evolved, and from where did they originate? Int. Microbiol. 2006, 9, 9-19.
    • (2006) Int. Microbiol , vol.9 , pp. 9-19
    • Liras, P.1    Martín, J.F.2
  • 86
  • 88
    • 0037249633 scopus 로고    scopus 로고
    • The TIGRFAMs database of protein families
    • Haft, D.H.; Selengut, J.D.; White, O. The TIGRFAMs database of protein families. Nucleic Acids Res. 2003, 31, 371-373.
    • (2003) Nucleic Acids Res , vol.31 , pp. 371-373
    • Haft, D.H.1    Selengut, J.D.2    White, O.3
  • 89
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: Multiple sequence alignment with high accuracy and high throughput
    • Edgar, R.C. MUSCLE: Multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 2004, 32, 1792-1797.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 90
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • Tamura, K.; Peterson, D.; Peterson, N.; Stecher, G.; Nei, M.; Kumar, S. MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28, 2731-2739.
    • (2011) Mol. Biol. Evol , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 91
    • 50249100595 scopus 로고    scopus 로고
    • A rapid bootstrap algorithm for the RAxML Web servers
    • Stamatakis, A.; Hoover, P.; Rougemont, J. A rapid bootstrap algorithm for the RAxML Web servers. Syst. Biol. 2008, 57, 758-771.
    • (2008) Syst. Biol , vol.57 , pp. 758-771
    • Stamatakis, A.1    Hoover, P.2    Rougemont, J.3
  • 93
    • 0029853148 scopus 로고    scopus 로고
    • WWW-Query: An on-line retrieval system for biological sequence banks
    • Perrière, G.; Gouy, M. WWW-Query: An on-line retrieval system for biological sequence banks. Biochemie 1996, 78, 364-369.
    • (1996) Biochemie , vol.78 , pp. 364-369
    • Perrière, G.1    Gouy, M.2
  • 94
    • 72449164089 scopus 로고    scopus 로고
    • Acquisition of prokaryotic genes by fungal genomes
    • Marcet-Houben, M.; Gabaldón, T. Acquisition of prokaryotic genes by fungal genomes. Trends Genet. 2010, 26, 5-8.
    • (2010) Trends Genet , vol.26 , pp. 5-8
    • Marcet-Houben, M.1    Gabaldón, T.2
  • 95
    • 68349157380 scopus 로고    scopus 로고
    • Insertion of horizontally transferred genes within conserved syntenic regions of yeast genomes
    • Rolland, T.; Neuvéglise, C.; Sacerdot, C.; Dujon, B. Insertion of horizontally transferred genes within conserved syntenic regions of yeast genomes. PLoS One 2009, 4, e6515.
    • (2009) PLoS One , vol.e6515 , pp. 4
    • Rolland, T.1    Neuvéglise, C.2    Sacerdot, C.3    Dujon, B.4
  • 96
    • 79151477225 scopus 로고    scopus 로고
    • Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi
    • Slot, J.C.; Rokas, A. Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi. Curr. Biol. 2011, 21, 134-139.
    • (2011) Curr. Biol , vol.21 , pp. 134-139
    • Slot, J.C.1    Rokas, A.2
  • 97
    • 84870846937 scopus 로고    scopus 로고
    • Physiological and Molecular Aspects of Ochratoxin A Biosynthesis
    • Geisen, R.; Schmidt-Heydt, M. Physiological and Molecular Aspects of Ochratoxin A Biosynthesis. In Physiology and Genetics. The Mycota XV; Anke, T., Weber, D., Eds.; Springer-Verlag: Heidelberg, Germany, 2009; pp. 353-376.
    • In Physiology and Genetics , vol.2009 , pp. 353-376
    • Geisen, R.1    Schmidt-Heydt, M.2
  • 98
    • 34250710858 scopus 로고    scopus 로고
    • Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
    • Rausch, C.; Hoof, I.; Weber, T.; Wohlleben, W.; Huson, D.H. Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution. BMC Evol. Biol. 2007, 7, 78.
    • (2007) BMC Evol. Biol , vol.7 , pp. 78
    • Rausch, C.1    Hoof, I.2    Weber, T.3    Wohlleben, W.4    Huson, D.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.