Coenzyme Q10 rescues ethanol-induced corneal fibroblast apoptosis through the inhibition of caspase-2 activation

Journal of Biological Chemistry

Volumn 288, Issue 17, 2013, Pages 11689-11704

  Chen, Chun Chen ^a,b   Liou, Shiow Wen ^a,f,g   Chen, Chi Chih ^d   Chen, Wen Chung ^d   Hu, Fung Rong ^f   Wang, I Jong ^f,h   Lin, Shing Jong ^b,c,e  

^a TAIPEI CITY HOSPITAL   (Taiwan)

^b Instituteof Clinical Medicine   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d Division of Cardiology   (Taiwan)

^e TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^g TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^h CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PATHWAYS; APOPTOTIC PROTEINS; CASPASE-3 ACTIVATION; CORNEAL FIBROBLASTS; MITOCHONDRIAL DAMAGE; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL MEMBRANES; REACTIVE OXYGEN SPECIES;

CELL CULTURE; CELL MEMBRANES; ETHANOL; FIBROBLASTS; MITOCHONDRIA;

CELL DEATH;

ALCOHOL; CASPASE 2; CASPASE 3; CYTOCHROME C; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UBIDECARENONE; DRUG DERIVATIVE; SOLVENT; UBIQUINONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CORNEA CELL; CORNEA FIBROBLAST; COW; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FIBROBLAST; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; ANIMAL; BIOSYNTHESIS; CATTLE; CELL CULTURE; CORNEA; CYTOLOGY; GENE EXPRESSION REGULATION; METABOLISM; MITOCHONDRION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 2; CASPASE 3; CATTLE; CELLS, CULTURED; CORNEA; ENZYME ACTIVATION; ETHANOL; FIBROBLASTS; GENE EXPRESSION REGULATION; MITOCHONDRIA; PROTEIN TRANSPORT; SOLVENTS; TUMOR SUPPRESSOR PROTEIN P53; UBIQUINONE;

MLCS; MLOWN;

EID: 84876896003     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.401844     Document Type: Article

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