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Volumn 11, Issue 1, 2010, Pages 111-121

Coenzyme Q10 in neuromuscular and neurodegenerative disorders

Author keywords

Coenzyme Q10; CoQ10 deficiency; Idebenone; Mitochondria; Mitochondrial diseases; Neurodegeneration; Statins

Indexed keywords

ADENOSINE TRIPHOSPHATE; ATORVASTATIN; CREATINE; CREATINE KINASE; EZETIMIBE; IDEBENONE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; REMACEMIDE; SIMVASTATIN; THIOCTIC ACID; UBIDECARENONE; DRUG DERIVATIVE; UBIQUINONE;

EID: 77949440226     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945010790031018     Document Type: Review
Times cited : (125)

References (80)
  • 3
    • 34250676955 scopus 로고    scopus 로고
    • Mitochondrial diseases: Therapeutic approaches
    • DiMauro S, Mancuso M. Mitochondrial diseases: therapeutic approaches. Biosci Rep 2007; 27: 125-37.
    • (2007) Biosci Rep , vol.27 , pp. 125-137
    • DiMauro, S.1    Mancuso, M.2
  • 4
    • 13844316604 scopus 로고    scopus 로고
    • Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial
    • Sandor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial. Neurology 2005; 64: 713-5.
    • (2005) Neurology , vol.64 , pp. 713-715
    • Sandor, P.S.1    Di Clemente, L.2    Coppola, G.3    Saenger, U.4    Fumal, A.5    Magis, D.6
  • 5
    • 33846246327 scopus 로고    scopus 로고
    • Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine
    • Hershey AD, Powers SW, Vockell AL, Lecates SL, Ellinor PL, Segers A, et al. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache 2007; 47: 73-80.
    • (2007) Headache , vol.47 , pp. 73-80
    • Hershey, A.D.1    Powers, S.W.2    Vockell, A.L.3    Lecates, S.L.4    Ellinor, P.L.5    Segers, A.6
  • 7
    • 33947423399 scopus 로고    scopus 로고
    • Coenzyme Q10 in the treatment of hypertension: A meta-analysis of the clinical trials
    • Rosenfeldt FL, Haas SJ, Krum H, Hadj A, Ng K, Leong JY, et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens 2007; 21: 297-306.
    • (2007) J Hum Hypertens , vol.21 , pp. 297-306
    • Rosenfeldt, F.L.1    Haas, S.J.2    Krum, H.3    Hadj, A.4    Ng, K.5    Leong, J.Y.6
  • 11
    • 33947586652 scopus 로고    scopus 로고
    • Some observations upon biochemical causes of ataxia and a new disease entity ubiquinone, CoQ10 deficiency
    • Land JM, Heales SJ, Duncan AJ, Hargreaves IP. Some observations upon biochemical causes of ataxia and a new disease entity ubiquinone, CoQ10 deficiency. Neurochem Res 2007; 32: 837-43.
    • (2007) Neurochem Res , vol.32 , pp. 837-843
    • Land, J.M.1    Heales, S.J.2    Duncan, A.J.3    Hargreaves, I.P.4
  • 12
    • 0037972522 scopus 로고    scopus 로고
    • Mitochondrial respiratory-chain diseases
    • DiMauro S, Schon EA. Mitochondrial respiratory-chain diseases. N Engl J Med 2003; 348: 2656-68.
    • (2003) N Engl J Med , vol.348 , pp. 2656-2668
    • DiMauro, S.1    Schon, E.A.2
  • 13
    • 0035910414 scopus 로고    scopus 로고
    • The rotary machine of the cell, ATP synthase
    • Noji H, Yoshida M. The rotary machine of the cell, ATP synthase. J Biol Chem 2001; 276: 1665-68.
    • (2001) J Biol Chem , vol.276 , pp. 1665-1668
    • Noji, H.1    Yoshida, M.2
  • 15
    • 58149381936 scopus 로고    scopus 로고
    • Mitochondrial production of reactive oxygen species: Role of complex I and quinone analogues
    • Fato R, Bergamini C, Leoni S, Lenaz G. Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues. Biofactors 2008; 32: 31-9.
    • (2008) Biofactors , vol.32 , pp. 31-39
    • Fato, R.1    Bergamini, C.2    Leoni, S.3    Lenaz, G.4
  • 16
    • 2342594384 scopus 로고    scopus 로고
    • The mitochondrial production of reactive oxygen species in relation to aging and pathology
    • Genova ML, Pich MM, Bernacchia A, Bianchi C, Bovina A, Bovina C, et al. The mitochondrial production of reactive oxygen species in relation to aging and pathology. Ann N Y Acad Sci 2004; 1011: 86-100.
    • (2004) Ann N Y Acad Sci , vol.1011 , pp. 86-100
    • Genova, M.L.1    Pich, M.M.2    Bernacchia, A.3    Bianchi, C.4    Bovina, A.5    Bovina, C.6
  • 17
    • 33745628757 scopus 로고    scopus 로고
    • Generation of superoxide by the mitochondrial Complex I
    • Grivennikova VG, Vinogradov AD. Generation of superoxide by the mitochondrial Complex I. Biochim Biophys Acta 2006; 1757: 553-61.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 553-561
    • Grivennikova, V.G.1    Vinogradov, A.D.2
  • 18
    • 62249115660 scopus 로고    scopus 로고
    • Mitochondrial pathways for ROS formation and myocardial injury: The relevance of p66(Shc) and monoamine oxidase
    • Di Lisa F, Kaludercic N, Carpi A, Menabò R, Giorgio M. Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase. Basic Res Cardiol 2009; 104: 131-9.
    • (2009) Basic Res Cardiol , vol.104 , pp. 131-139
    • Di Lisa, F.1    Kaludercic, N.2    Carpi, A.3    Menabò, R.4    Giorgio, M.5
  • 19
    • 14744287295 scopus 로고    scopus 로고
    • Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10
    • Somayajulu M, McCarthy S, Hung M, Sikorska M, Borowy-Borowski H, Pandey S. Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10. Neurobiol Dis 2005; 18: 618-27.
    • (2005) Neurobiol Dis , vol.18 , pp. 618-627
    • Somayajulu, M.1    McCarthy, S.2    Hung, M.3    Sikorska, M.4    Borowy-Borowski, H.5    Pandey, S.6
  • 20
    • 0031005815 scopus 로고    scopus 로고
    • Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra
    • Ferrante RJ, Schulz JB, Kowall NW, Beal MF. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res 1997; 753: 157-62.
    • (1997) Brain Res , vol.753 , pp. 157-162
    • Ferrante, R.J.1    Schulz, J.B.2    Kowall, N.W.3    Beal, M.F.4
  • 21
    • 2442497176 scopus 로고    scopus 로고
    • Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients
    • Winkler-Stuck K, Wiedemann FR, Wallesch CW, Kunz WS. Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients. J Neurol Sci 2004; 220: 41-8.
    • (2004) J Neurol Sci , vol.220 , pp. 41-48
    • Winkler-Stuck, K.1    Wiedemann, F.R.2    Wallesch, C.W.3    Kunz, W.S.4
  • 22
    • 33646878524 scopus 로고    scopus 로고
    • Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons
    • Kooncumchoo P, Sharma S, Porter J, Govitrapong P, Ebadi M. Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons. J Mol Neurosci 2006; 28: 125-41.
    • (2006) J Mol Neurosci , vol.28 , pp. 125-141
    • Kooncumchoo, P.1    Sharma, S.2    Porter, J.3    Govitrapong, P.4    Ebadi, M.5
  • 23
    • 39849084236 scopus 로고    scopus 로고
    • Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism
    • Cleren C, Yang L, Lorenzo B, Calingasan NY, Schomer A, Sireci A, et al. Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism. J Neurochem 2008; 104: 1613-21.
    • (2008) J Neurochem , vol.104 , pp. 1613-1621
    • Cleren, C.1    Yang, L.2    Lorenzo, B.3    Calingasan, N.Y.4    Schomer, A.5    Sireci, A.6
  • 25
    • 26244447857 scopus 로고    scopus 로고
    • CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats
    • Moreira PI, Santos MS, Sena C, Nunes E, Seiça R, Oliveira CR. CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Exp Neurol 2005; 196: 112-9.
    • (2005) Exp Neurol , vol.196 , pp. 112-119
    • Moreira, P.I.1    Santos, M.S.2    Sena, C.3    Nunes, E.4    Seiça, R.5    Oliveira, C.R.6
  • 26
    • 58149373850 scopus 로고    scopus 로고
    • Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: An in vivo volume MRI study
    • Li G, Jack CR, Yang XF, Yang ES. Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study. Biofactors 2008; 32: 169-78.
    • (2008) Biofactors , vol.32 , pp. 169-178
    • Li, G.1    Jack, C.R.2    Yang, X.F.3    Yang, E.S.4
  • 27
    • 33646596554 scopus 로고    scopus 로고
    • Coenzyme Q10 modulates cognitive impairment against intracerebroventri-cular injection of streptozotocin in rats
    • Ishrat T, Khan MB, Hoda MN, Yousuf S, Ahmad M, Ansari MA, et al. Coenzyme Q10 modulates cognitive impairment against intracerebroventri-cular injection of streptozotocin in rats. Behav Brain Res 2006; 171: 9-16.
    • (2006) Behav Brain Res , vol.171 , pp. 9-16
    • Ishrat, T.1    Khan, M.B.2    Hoda, M.N.3    Yousuf, S.4    Ahmad, M.5    Ansari, M.A.6
  • 28
    • 13844298846 scopus 로고    scopus 로고
    • Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice
    • McDonald SR, Sohal RS, Forster MJ. Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. Free Radic Biol Med 2005; 38: 729-36.
    • (2005) Free Radic Biol Med , vol.38 , pp. 729-736
    • McDonald, S.R.1    Sohal, R.S.2    Forster, M.J.3
  • 29
    • 29244483093 scopus 로고    scopus 로고
    • Kasparová S, Sumbalová Z, Bystrick?? P, Kucharská J, Liptaj T, Mlynárik V, et al. Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. Neurochem Int 2006; 48: 93-9.
    • Kasparová S, Sumbalová Z, Bystrick?? P, Kucharská J, Liptaj T, Mlynárik V, et al. Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. Neurochem Int 2006; 48: 93-9.
  • 31
    • 70349487545 scopus 로고    scopus 로고
    • Neuroprotective Effects of Tetracyclines: Molecular Targets, Animal Models and Human Disease
    • Orsucci D, Calsolaro V, Mancuso M, Siciliano G. Neuroprotective Effects of Tetracyclines: Molecular Targets, Animal Models and Human Disease. CNS Neurol Disord Drug Targets 2009; 8: 222-31.
    • (2009) CNS Neurol Disord Drug Targets , vol.8 , pp. 222-231
    • Orsucci, D.1    Calsolaro, V.2    Mancuso, M.3    Siciliano, G.4
  • 32
    • 31644439986 scopus 로고    scopus 로고
    • Com-bination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice
    • Stack EC, Smith KM, Ryu H, Cormier K, Chen M, Hagerty SW, et al. Com-bination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice. Biochim Biophys Acta 2006; 1762: 373-80.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 373-380
    • Stack, E.C.1    Smith, K.M.2    Ryu, H.3    Cormier, K.4    Chen, M.5    Hagerty, S.W.6
  • 33
    • 63349103959 scopus 로고    scopus 로고
    • Water-soluble Coenzyme Q10 formulation (Q-ter) promotes outer hair cell survival in a guinea pig model of noise induced hearing loss (NIHL)
    • Fetoni AR, Piacentini R, Fiorita A, Paludetti G, Troiani D. Water-soluble Coenzyme Q10 formulation (Q-ter) promotes outer hair cell survival in a guinea pig model of noise induced hearing loss (NIHL). Brain Res 2009; 1257: 108-16.
    • (2009) Brain Res , vol.1257 , pp. 108-116
    • Fetoni, A.R.1    Piacentini, R.2    Fiorita, A.3    Paludetti, G.4    Troiani, D.5
  • 34
    • 40049094038 scopus 로고    scopus 로고
    • Antioxidant protection against acoustic trauma by coadministration of idebenone and vitamin E
    • Fetoni AR, Ferraresi A, Greca CL, Rizzo D, Sergi B, Tringali G, et al. Antioxidant protection against acoustic trauma by coadministration of idebenone and vitamin E. Neuroreport 2008; 19: 277-81.
    • (2008) Neuroreport , vol.19 , pp. 277-281
    • Fetoni, A.R.1    Ferraresi, A.2    Greca, C.L.3    Rizzo, D.4    Sergi, B.5    Tringali, G.6
  • 35
    • 33847404036 scopus 로고    scopus 로고
    • Mutations in coenzyme Q10 biosynthetic genes
    • DiMauro S, Quinzii CM, Hirano M. Mutations in coenzyme Q10 biosynthetic genes. J Clin Invest 2007; 117: 587-9.
    • (2007) J Clin Invest , vol.117 , pp. 587-589
    • DiMauro, S.1    Quinzii, C.M.2    Hirano, M.3
  • 37
    • 34248171499 scopus 로고    scopus 로고
    • The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene
    • Gempel K, Topaloglu H, Talim B, Schneiderat P, Schoser BG, Hans VH, et al. The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. Brain 2007; 130: 2037-44.
    • (2007) Brain , vol.130 , pp. 2037-2044
    • Gempel, K.1    Topaloglu, H.2    Talim, B.3    Schneiderat, P.4    Schoser, B.G.5    Hans, V.H.6
  • 39
    • 33847347629 scopus 로고    scopus 로고
    • Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders
    • Mollet J, Giurgea I, Schlemmer D, Dallner G, Chretien D, Delahodde A, et al. Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders. J Clin Invest 2007; 117: 765-72.
    • (2007) J Clin Invest , vol.117 , pp. 765-772
    • Mollet, J.1    Giurgea, I.2    Schlemmer, D.3    Dallner, G.4    Chretien, D.5    Delahodde, A.6
  • 40
    • 33845232634 scopus 로고    scopus 로고
    • Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations
    • Lòpez LC, Schuelke M, Quinzii CM, Kanki T, Rodenburg RJ, Naini A, et al. Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. Am J Hum Genet 2006; 79: 1125-9.
    • (2006) Am J Hum Genet , vol.79 , pp. 1125-1129
    • Lòpez, L.C.1    Schuelke, M.2    Quinzii, C.M.3    Kanki, T.4    Rodenburg, R.J.5    Naini, A.6
  • 41
    • 31544480133 scopus 로고    scopus 로고
    • A Mutation in Para-Hydroxybenzoate-Polyprenyl Transferase (COQ2) Causes Primary Coenzyme Q10 Deficiency
    • Quinzii CM, Naini A, Salviati L, Trevisson E, Navas P, Dimauro S, et al. A Mutation in Para-Hydroxybenzoate-Polyprenyl Transferase (COQ2) Causes Primary Coenzyme Q10 Deficiency. Am J Hum Genet 2006; 78: 345-9.
    • (2006) Am J Hum Genet , vol.78 , pp. 345-349
    • Quinzii, C.M.1    Naini, A.2    Salviati, L.3    Trevisson, E.4    Navas, P.5    Dimauro, S.6
  • 42
    • 13244277454 scopus 로고    scopus 로고
    • Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation
    • Quinzii CM, Kattah AG, Naini A, Akman HO, Mootha VK, DiMauro S, et al. Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation. Neurology 2005; 64: 539-41.
    • (2005) Neurology , vol.64 , pp. 539-541
    • Quinzii, C.M.1    Kattah, A.G.2    Naini, A.3    Akman, H.O.4    Mootha, V.K.5    DiMauro, S.6
  • 44
    • 41149134880 scopus 로고    scopus 로고
    • CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures
    • Mollet J, Delahodde A, Serre V, Chretien D, Schlemmer D, Lombes A, et al. CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures. Am J Hum Genet 2008; 82: 623-30.
    • (2008) Am J Hum Genet , vol.82 , pp. 623-630
    • Mollet, J.1    Delahodde, A.2    Serre, V.3    Chretien, D.4    Schlemmer, D.5    Lombes, A.6
  • 45
    • 41149121580 scopus 로고    scopus 로고
    • ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency
    • Lagier-Tourenne C, Tazir M, López LC, Quinzii CM, Assoum M, Drouot N, et al. ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet 2008; 82: 661-72.
    • (2008) Am J Hum Genet , vol.82 , pp. 661-672
    • Lagier-Tourenne, C.1    Tazir, M.2    López, L.C.3    Quinzii, C.M.4    Assoum, M.5    Drouot, N.6
  • 46
    • 65549087610 scopus 로고    scopus 로고
    • A Nonsense Mutation in COQ9 Causes Autosomal-Recessive Neonatal-Onset Primary Coenzyme Q10 Deficiency: A Potentially Treatable Form of Mitochondrial Disease
    • Duncan AJ, Bitner-Glindzicz M, Meunier B, Costello H, Hargreaves IP, López LC, et al. A Nonsense Mutation in COQ9 Causes Autosomal-Recessive Neonatal-Onset Primary Coenzyme Q10 Deficiency: A Potentially Treatable Form of Mitochondrial Disease. Am J Hum Genet 2009; 84: 558-66.
    • (2009) Am J Hum Genet , vol.84 , pp. 558-566
    • Duncan, A.J.1    Bitner-Glindzicz, M.2    Meunier, B.3    Costello, H.4    Hargreaves, I.P.5    López, L.C.6
  • 47
    • 33744526447 scopus 로고    scopus 로고
    • Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation
    • Artuch R, Brea-Calvo G, Briones P, Aracil A, Galván M, Espinós C, et al. Cerebellar ataxia with coenzyme Q10 deficiency: diagnosis and follow-up after coenzyme Q10 supplementation. J Neurol Sci 2006; 246: 153-8.
    • (2006) J Neurol Sci , vol.246 , pp. 153-158
    • Artuch, R.1    Brea-Calvo, G.2    Briones, P.3    Aracil, A.4    Galván, M.5    Espinós, C.6
  • 48
    • 45949099527 scopus 로고    scopus 로고
    • Early coenzyme Q10 supplementation in primary coenzyme Q10 deficiency
    • Montini G, Malaventura C, Salviati L. Early coenzyme Q10 supplementation in primary coenzyme Q10 deficiency. N Engl J Med 2008; 358: 2849-50.
    • (2008) N Engl J Med , vol.358 , pp. 2849-2850
    • Montini, G.1    Malaventura, C.2    Salviati, L.3
  • 49
    • 34248151929 scopus 로고    scopus 로고
    • Infantile and pediatric quinone deficiency diseases
    • Rotig A, Mollet J, Rio M, Munnich A. Infantile and pediatric quinone deficiency diseases. Mitochondrion 2007; 7: S112-21.
    • (2007) Mitochondrion , vol.7
    • Rotig, A.1    Mollet, J.2    Rio, M.3    Munnich, A.4
  • 51
    • 33746094282 scopus 로고    scopus 로고
    • Muscle coenzyme Q10 concentrations in patients with probable and definite diagnosis of respiratory chain disorders
    • Montero R, Artuch R, Briones P, Nascimento A, García-Cazorla A, Vilaseca MA, et al. Muscle coenzyme Q10 concentrations in patients with probable and definite diagnosis of respiratory chain disorders. Biofactors 2005; 25: 109-15.
    • (2005) Biofactors , vol.25 , pp. 109-115
    • Montero, R.1    Artuch, R.2    Briones, P.3    Nascimento, A.4    García-Cazorla, A.5    Vilaseca, M.A.6
  • 52
    • 40349092904 scopus 로고    scopus 로고
    • Systematic evaluation of muscle coenzyme Q10 content in children with mitochondrial respiratory chain enzyme deficiencies
    • Miles MV, Miles L, Tang PH, Horn PS, Steele PE, DeGrauw AJ, et al. Systematic evaluation of muscle coenzyme Q10 content in children with mitochondrial respiratory chain enzyme deficiencies. Mitochondrion 2008; 8: 170-80.
    • (2008) Mitochondrion , vol.8 , pp. 170-180
    • Miles, M.V.1    Miles, L.2    Tang, P.H.3    Horn, P.S.4    Steele, P.E.5    DeGrauw, A.J.6
  • 54
    • 4344684797 scopus 로고    scopus 로고
    • Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes)
    • Berbel-Garcia A, Barbera-Farre JR, Etessam JP, Salio AM, Cabello A, Gutierrez-Rivas E, et al. Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes). Clin Neuropharmacol 2004; 27: 187-91.
    • (2004) Clin Neuropharmacol , vol.27 , pp. 187-191
    • Berbel-Garcia, A.1    Barbera-Farre, J.R.2    Etessam, J.P.3    Salio, A.M.4    Cabello, A.5    Gutierrez-Rivas, E.6
  • 55
    • 58749085705 scopus 로고    scopus 로고
    • Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: A long-term follow-up study
    • Haginoya K, Miyabayashi S, Kikuchi M, Kojima A, Yamamoto K, Omura K, et al. Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study. J Neurol Sci 2009; 278: 112-4.
    • (2009) J Neurol Sci , vol.278 , pp. 112-114
    • Haginoya, K.1    Miyabayashi, S.2    Kikuchi, M.3    Kojima, A.4    Yamamoto, K.5    Omura, K.6
  • 56
    • 0030612535 scopus 로고    scopus 로고
    • Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study
    • Chen RS, Huang CC, Chu NS. Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study. Eur Neurol 1997; 37: 212-8.
    • (1997) Eur Neurol , vol.37 , pp. 212-218
    • Chen, R.S.1    Huang, C.C.2    Chu, N.S.3
  • 58
    • 10044235066 scopus 로고    scopus 로고
    • Isoprostanes: Markers and mediators of oxidative stress
    • Montuschi P, Barnes PJ, Roberts LJ II. Isoprostanes: markers and mediators of oxidative stress. FASEB J 2004; 18: 1791-800.
    • (2004) FASEB J , vol.18 , pp. 1791-1800
    • Montuschi, P.1    Barnes, P.J.2    Roberts II, L.J.3
  • 59
    • 0037403926 scopus 로고    scopus 로고
    • Patients with dystrophinopathy show evidence of increased oxidative stress
    • Rodriguez MC, Tarnopolsky MA. Patients with dystrophinopathy show evidence of increased oxidative stress. Free Radic Biol Med 2003; 34: 1217-20.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1217-1220
    • Rodriguez, M.C.1    Tarnopolsky, M.A.2
  • 60
    • 0034577267 scopus 로고    scopus 로고
    • Cytogenetic damage in peripheral lymphocytes of mitochondrial disease patients
    • Naccarati A, Molinu S, Mancuso M, Siciliano G, Migliore L. Cytogenetic damage in peripheral lymphocytes of mitochondrial disease patients. Neurol Sci 2000; 21: S963-5.
    • (2000) Neurol Sci , vol.21
    • Naccarati, A.1    Molinu, S.2    Mancuso, M.3    Siciliano, G.4    Migliore, L.5
  • 61
    • 0033216635 scopus 로고    scopus 로고
    • Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes
    • Tomasetti M, Littarru GP, Stocker R, Alleva R. Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes. Free Radic Biol Med 1999; 27: 1027-32.
    • (1999) Free Radic Biol Med , vol.27 , pp. 1027-1032
    • Tomasetti, M.1    Littarru, G.P.2    Stocker, R.3    Alleva, R.4
  • 62
    • 0345832230 scopus 로고    scopus 로고
    • Evaluation of cytogenetic and DNA damage in mitochondrial disease patients: Effects of coenzyme Q10 therapy
    • Migliore L, Molinu S, Naccarati A, Mancuso M, Rocchi A, Siciliano G. Evaluation of cytogenetic and DNA damage in mitochondrial disease patients: effects of coenzyme Q10 therapy. Mutagenesis 2004; 19: 43-9.
    • (2004) Mutagenesis , vol.19 , pp. 43-49
    • Migliore, L.1    Molinu, S.2    Naccarati, A.3    Mancuso, M.4    Rocchi, A.5    Siciliano, G.6
  • 63
    • 34249826635 scopus 로고    scopus 로고
    • The Role of Coenzyme Q10 in Statin-Associated Myopathy - A Systematic Review
    • Marcoff L, Thompson PD. The Role of Coenzyme Q10 in Statin-Associated Myopathy - A Systematic Review. J Am Coll Cardiol 2007; 49: 2231-7.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2231-2237
    • Marcoff, L.1    Thompson, P.D.2
  • 66
    • 33746848052 scopus 로고    scopus 로고
    • Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: A randomised trial
    • Berthold HK, Naini A, Di Mauro S, Hallikainen M, Gylling H, Krone W, et al. Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial. Drug Saftey 2006; 29: 703-12.
    • (2006) Drug Saftey , vol.29 , pp. 703-712
    • Berthold, H.K.1    Naini, A.2    Di Mauro, S.3    Hallikainen, M.4    Gylling, H.5    Krone, W.6
  • 67
    • 36049005012 scopus 로고    scopus 로고
    • Hokuriku lipid research group. Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: A randomized double-blind study
    • Mabuchi H, Nohara A, Kobayashi J, Kawashiri MA, Katsuda S, Inazu A, et al. Hokuriku lipid research group. Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study. Atherosclerosis 2007; 195: e182-9.
    • (2007) Atherosclerosis , vol.195
    • Mabuchi, H.1    Nohara, A.2    Kobayashi, J.3    Kawashiri, M.A.4    Katsuda, S.5    Inazu, A.6
  • 68
    • 54249094205 scopus 로고    scopus 로고
    • The coenzyme Q10 status of the brain regions of Parkinson's disease patients
    • Hargreaves IP, Lane A, Sleiman PM. The coenzyme Q10 status of the brain regions of Parkinson's disease patients. Neurosci Lett 2008; 447: 17-9.
    • (2008) Neurosci Lett , vol.447 , pp. 17-19
    • Hargreaves, I.P.1    Lane, A.2    Sleiman, P.M.3
  • 69
    • 0036771852 scopus 로고    scopus 로고
    • Effects of coenzyme Q10 in early Parkinson disease: Evidence of slowing of the functional decline
    • Shults CW, Oakes D, Kieburtz K, Beal MF, Haas R, Plumb S, et al. Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline. Arch Neurol 2002; 59: 1541-50.
    • (2002) Arch Neurol , vol.59 , pp. 1541-1550
    • Shults, C.W.1    Oakes, D.2    Kieburtz, K.3    Beal, M.F.4    Haas, R.5    Plumb, S.6
  • 70
    • 34447252358 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease
    • Storch A, Jost WH, Vieregge P, Spiegel J, Greulich W, Durner J, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease. Arch Neurol 2007; 64: 938-44.
    • (2007) Arch Neurol , vol.64 , pp. 938-944
    • Storch, A.1    Jost, W.H.2    Vieregge, P.3    Spiegel, J.4    Greulich, W.5    Durner, J.6
  • 71
    • 33846115045 scopus 로고    scopus 로고
    • A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease
    • The NINDS NET-PD Investigators
    • The NINDS NET-PD Investigators. A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. Neurology 2007; 68: 20-8.
    • (2007) Neurology , vol.68 , pp. 20-28
  • 72
    • 49249087500 scopus 로고    scopus 로고
    • Short-term effects of coenzyme Q10 in progressive supranuclear palsy: A randomized, placebo-controlled trial
    • Stamelou M, Reuss A, Pilatus U, Magerkurth J, Niklowitz P, Eggert KM, et al. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial. Mov Disord 2008; 23: 942-9.
    • (2008) Mov Disord , vol.23 , pp. 942-949
    • Stamelou, M.1    Reuss, A.2    Pilatus, U.3    Magerkurth, J.4    Niklowitz, P.5    Eggert, K.M.6
  • 75
    • 10644241578 scopus 로고    scopus 로고
    • An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients
    • Sohmiya M, Tanaka M, Suzuki Y, Tanino Y, Okamoto K, Yamamoto Y. An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. J Neurol Sci 2005; 228: 49-53.
    • (2005) J Neurol Sci , vol.228 , pp. 49-53
    • Sohmiya, M.1    Tanaka, M.2    Suzuki, Y.3    Tanino, Y.4    Okamoto, K.5    Yamamoto, Y.6
  • 78
    • 52249097807 scopus 로고    scopus 로고
    • Idebenone in Friedreich's ataxia
    • Tonon C, Lodi R. Idebenone in Friedreich's ataxia. Expert Opin Pharmacother 2008; 9: 2327-37.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 2327-2337
    • Tonon, C.1    Lodi, R.2
  • 79
    • 56049088295 scopus 로고    scopus 로고
    • Coenzyme Q10 and vitamin E deficiency in Friedreich's ataxia: Predictor of efficacy of vitamin E and coenzyme Q10 therapy
    • Cooper JM, Korlipara LV, Hart PE, Bradley JL, Schapira AH. Coenzyme Q10 and vitamin E deficiency in Friedreich's ataxia: predictor of efficacy of vitamin E and coenzyme Q10 therapy. Eur J Neurol. 2008; 15: 1371-9.
    • (2008) Eur J Neurol , vol.15 , pp. 1371-1379
    • Cooper, J.M.1    Korlipara, L.V.2    Hart, P.E.3    Bradley, J.L.4    Schapira, A.H.5
  • 80
    • 34548606803 scopus 로고    scopus 로고
    • Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: A randomised, placebo-controlled trial
    • Di Prospero NA, Baker A, Jeffries N, Fischbeck KH. Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial. Lancet Neurol 2007; 6: 878-86.
    • (2007) Lancet Neurol , vol.6 , pp. 878-886
    • Di Prospero, N.A.1    Baker, A.2    Jeffries, N.3    Fischbeck, K.H.4


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