DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

Oncogene

Volumn 28, Issue 18, 2009, Pages 1949-1959

  Olsson, M ^a   Vakifahmetoglu, H ^a   Abruzzo, P M ^a,c   Hogstrand K ^b   Grandien, A ^b   Zhivotovsky, B ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Apoptosis; Caspase 2; Caspase 8; DISC; DNA damage

Indexed keywords

CASPASE 2; CASPASE 8; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CISPLATIN; COMPLEMENTARY DNA; CYTOCHROME C; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; ETOPOSIDE; FAS ANTIGEN; FLUOROURACIL; MESSENGER RNA; P53 INDUCED PROTEIN WITH A DEATH DOMAIN; PROTEIN BID; PROTEIN P53; RETROVIRUS VECTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; FLICE INHIBITORY PROTEIN;

APOPTOSIS; ARTICLE; CELL STRAIN HCT116; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; CHEMISTRY; DRUG EFFECT; GENETICS; KINETICS; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANTIGENS, CD95; APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 2; CASPASE 8; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS; DNA DAMAGE; ENZYME ACTIVATION; FLUOROURACIL; GENES, P53; HCT116 CELLS; HUMANS; KINETICS; RNA, SMALL INTERFERING; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 66149103719     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.36     Document Type: Article

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