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Volumn 13, Issue 3, 2013, Pages 353-364

Flax terpenoid pathway as a source of health promoting compounds

Author keywords

Antioxidant; Flax; Isoprenoid; Mechanism; Signaling; Terpenoid

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ANTIOXIDANT; BETA CAROTENE; CAMPESTEROL; CANNABIDIOL; CANNABINOID; CAROTENOID; CASPASE 8; CD36 ANTIGEN; CYCLIC AMP; GAMMA TOCOPHEROL; INDUCIBLE NITRIC OXIDE SYNTHASE; INHIBITOR OF APOPTOSIS PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE A2; PHYTOSTEROL; PLATELET DERIVED GROWTH FACTOR; PREGNANE X RECEPTOR; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; SITOSTEROL; SQUALENE; STIGMASTEROL; TERPENOID; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; XANTHOPHYLL; ZEAXANTHIN;

EID: 84876841596     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/1389557511313030004     Document Type: Article
Times cited : (10)

References (127)
  • 2
    • 70349434717 scopus 로고    scopus 로고
    • Chemical composition and molecular structure of fibers from transgenic flax producing polyhydroxybutyrate, and mechanical properties and platelet aggregation of composite materials containing these fibers
    • Szopa, J.; Wrobel-Kwiatkowska, M.; Kulma, A.; Zuk, M.; Skorkowska-Telichowska, K.; Dyminska, L.; Maczka, M.; Hanuza, J.; Zebrowski, J.; Preisner, M. Chemical composition and molecular structure of fibers from transgenic flax producing polyhydroxybutyrate, and mechanical properties and platelet aggregation of composite materials containing these fibers. Compos Sci. Technol, 2009, 69, 2438-2446.
    • (2009) Compos Sci. Technol , vol.69 , pp. 2438-2446
    • Szopa, J.1    Wrobel-Kwiatkowska, M.2    Kulma, A.3    Zuk, M.4    Skorkowska-Telichowska, K.5    Dyminska, L.6    Maczka, M.7    Hanuza, J.8    Zebrowski, J.9    Preisner, M.10
  • 3
    • 84857139286 scopus 로고    scopus 로고
    • Polypropylene composites with natural fibers and wood - General mechanical property profiles
    • Sobczak, L.; Lang, R.W.; Haider, A. Polypropylene composites with natural fibers and wood - General mechanical property profiles. Compos Sci Technol, 2012, 72, 550-557.
    • (2012) Compos Sci Technol , vol.72 , pp. 550-557
    • Sobczak, L.1    Lang, R.W.2    Haider, A.3
  • 4
    • 80051931324 scopus 로고    scopus 로고
    • Fractionation of flax shives with pressurized aqueous ethanol
    • Buranov, A.U.; Mazza, G. Fractionation of flax shives with pressurized aqueous ethanol. Ind Crop Prod., 2012, 35, 77-87.
    • (2012) Ind Crop Prod , vol.35 , pp. 77-87
    • Buranov, A.U.1    Mazza, G.2
  • 6
    • 84856253004 scopus 로고    scopus 로고
    • Flaxseed dietary fiber supplements for suppression of appetite and food intake
    • Ibrugger, S.; Kristensen, M.; Mikkelsen, M.S.; Astrup, A. Flaxseed dietary fiber supplements for suppression of appetite and food intake. Appetite, 2012, 58, 490-495.
    • (2012) Appetite , vol.58 , pp. 490-495
    • Ibrugger, S.1    Kristensen, M.2    Mikkelsen, M.S.3    Astrup, A.4
  • 8
    • 28244479352 scopus 로고    scopus 로고
    • Volatile science? Metabolic engineering of terpenoids in plants
    • Aharoni, A.; Jongsma, M.A.; Bouwmeester, H.J. Volatile science? Metabolic engineering of terpenoids in plants. Trends Plant Sci., 2005, 10, 594-602.
    • (2005) Trends Plant Sci , vol.10 , pp. 594-602
    • Aharoni, A.1    Jongsma, M.A.2    Bouwmeester, H.J.3
  • 9
    • 33845736982 scopus 로고    scopus 로고
    • Biosynthesis and engineering of isoprenoid small molecules
    • Withers, S.T.; Keasling, J.D. Biosynthesis and engineering of isoprenoid small molecules. Appl Microbiol Biotechnol, 2007, 73, 980-990.
    • (2007) Appl Microbiol Biotechnol , vol.73 , pp. 980-990
    • Withers, S.T.1    Keasling, J.D.2
  • 10
    • 33747215629 scopus 로고    scopus 로고
    • Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves
    • Bartram, S.; Jux, A.; Gleixner, G.; Boland, W. Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves. Phytochemistry, 2006, 67, 1661-1672.
    • (2006) Phytochemistry , vol.67 , pp. 1661-1672
    • Bartram, S.1    Jux, A.2    Gleixner, G.3    Boland, W.4
  • 12
    • 77953137753 scopus 로고    scopus 로고
    • Biosynthesis, regulation and functions of tocochromanols in plants
    • Mene-Saffrane, L.; DellaPenna, D. Biosynthesis, regulation and functions of tocochromanols in plants. Plant Physiol Bioch., 2010, 48, 301-309.
    • (2010) Plant Physiol Bioch , vol.48 , pp. 301-309
    • Mene-Saffrane, L.1    Dellapenna, D.2
  • 13
    • 84860395687 scopus 로고    scopus 로고
    • The influence of carotenoid biosynthesis modification on the Fusarium culmorum and Fusarium oxysporum resistance in flax
    • Boba, A.; Kulma, A.; Kostyn, K.; Starzycki, M.; Starzycka, E.; Szopa, J. The influence of carotenoid biosynthesis modification on the Fusarium culmorum and Fusarium oxysporum resistance in flax. Physiol Mol Plant P., 2011, 76, 39-47.
    • (2011) Physiol Mol Plant P , vol.76 , pp. 39-47
    • Boba, A.1    Kulma, A.2    Kostyn, K.3    Starzycki, M.4    Starzycka, E.5    Szopa, J.6
  • 14
    • 0034657215 scopus 로고    scopus 로고
    • Plant sterols, biosynthesis, biological function and their importance to human nutrition
    • Piironen, V.; Lindsay, D.G.; Miettinen, T.A.; Toivo, J.; Lampi, A-M. Plant sterols, biosynthesis, biological function and their importance to human nutrition. J Sci Food Agr., 2000, 80, 939-966.
    • (2000) J Sci Food Agr , vol.80 , pp. 939-966
    • Piironen, V.1    Lindsay, D.G.2    Miettinen, T.A.3    Toivo, J.4    Lampi, A.-M.5
  • 16
    • 36348946871 scopus 로고    scopus 로고
    • Tocopherol, tocotrienol and plant sterol contents of vegetable oils and industrial fats
    • Schwartz, H.; Ollilainen, V.; Piironen, V.; Lampi, A-M. Tocopherol, tocotrienol and plant sterol contents of vegetable oils and industrial fats. J Food Compos Anal, 2008, 21, 152-161.
    • (2008) J Food Compos Anal , vol.21 , pp. 152-161
    • Schwartz, H.1    Ollilainen, V.2    Piironen, V.3    Lampi, A.-M.4
  • 17
    • 0030912065 scopus 로고    scopus 로고
    • Differences in free sterols content and composition associated with somatic embryogenesis, shoot organogenesis and calli growth of flax
    • Cunha, A.; Fernandes -Ferreira, M. Differences in free sterols content and composition associated with somatic embryogenesis, shoot organogenesis and calli growth of flax. Plant Sci., 1997, 124, 97-105.
    • (1997) Plant Sci , vol.124 , pp. 97-105
    • Cunha, A.1    Fernandes-Ferreira, M.2
  • 18
    • 77956907584 scopus 로고    scopus 로고
    • Enrichment of Carotenoids in Flaxseed by Introducing a Bacterial Phytoene Synthase Gene Plant Secondary Metabolism Engineering
    • Edited by Walker JM, Humana Press
    • Fujisawa, M.; Misawa, N.; Fett-Neto, A.G. Enrichment of Carotenoids in Flaxseed by Introducing a Bacterial Phytoene Synthase Gene Plant Secondary Metabolism Engineering. In Volume 643. Edited by Walker JM, Humana Press, Method Mol Biol., 2008, 201-211.
    • (2008) Method Mol Biol , vol.643 , pp. 201-211
    • Fujisawa, M.1    Misawa, N.2    Fett-Neto, A.G.3
  • 19
    • 43849088631 scopus 로고    scopus 로고
    • Chemical composition and oxidative stability of flax, safflower and poppy seed and seed oils
    • Bozan, B.; Temelli, F. Chemical composition and oxidative stability of flax, safflower and poppy seed and seed oils. Bioresour Technol, 2008, 99, 6354-6359.
    • (2008) Bioresour Technol , vol.99 , pp. 6354-6359
    • Bozan, B.1    Temelli, F.2
  • 21
    • 34548311578 scopus 로고    scopus 로고
    • Recent advances in Cannabis sativa research, biosynthetic studies and its potential in biotechnology
    • Sirikantaramas, S.; Taura, F.; Morimoto, S.; Shoyama, Y. Recent advances in Cannabis sativa research, biosynthetic studies and its potential in biotechnology. Curr Pharm Biotechnol, 2007, 8, 237-243.
    • (2007) Curr Pharm Biotechnol , vol.8 , pp. 237-243
    • Sirikantaramas, S.1    Taura, F.2    Morimoto, S.3    Shoyama, Y.4
  • 22
    • 0037376117 scopus 로고    scopus 로고
    • Singlet oxygen quenching by dietary carotenoids in a model membrane environment
    • Cantrell, A.; McGarvey, D.J.; Truscott, T.G.; Rancan, F.; Bohm, F. Singlet oxygen quenching by dietary carotenoids in a model membrane environment. Arch Biochem Biophys., 2003, 412, 47-54.
    • (2003) Arch Biochem Biophys , vol.412 , pp. 47-54
    • Cantrell, A.1    McGarvey, D.J.2    Truscott, T.G.3    Rancan, F.4    Bohm, F.5
  • 23
    • 3042698411 scopus 로고    scopus 로고
    • Susceptibility of lipids from different flax cultivars to peroxidation and its lowering by added antioxidants
    • Lukaszewicz, M.; Szopa, J.; Krasowska, A. Susceptibility of lipids from different flax cultivars to peroxidation and its lowering by added antioxidants. Food Chem., 2004, 88, 225-231.
    • (2004) Food Chem , vol.88 , pp. 225-231
    • Lukaszewicz, M.1    Szopa, J.2    Krasowska, A.3
  • 25
    • 33645924688 scopus 로고    scopus 로고
    • Terpenoids as Plant Antioxidants
    • Grassmann, J. Terpenoids as Plant Antioxidants. Vitamins & Hormones, 2005, 72, 505-535.
    • (2005) Vitamins & Hormones , vol.72 , pp. 505-535
    • Grassmann, J.1
  • 26
    • 0027280282 scopus 로고
    • Radioprotection of mice by dietary squalene
    • Storm, H.M.; Oh, S.Y.; Kimler, B.F.; Norton, S. Radioprotection of mice by dietary squalene. Lipids, 1993, 28, 555-559.
    • (1993) Lipids , vol.28 , pp. 555-559
    • Storm, H.M.1    Oh, S.Y.2    Kimler, B.F.3    Norton, S.4
  • 27
    • 54249135351 scopus 로고    scopus 로고
    • Squalene selectively protects mouse bone marrow progenitors against cisplatin and carboplatin-induced cytotoxicity in vivo without protecting tumor growth
    • Das, B.; Antoon, R.; Tsuchida, R.; Lotfi, S.; Morozova, O.; Farhat, W.; Malkin, D.; Koren, G.; Yeger, H.; Baruchel, S. Squalene selectively protects mouse bone marrow progenitors against cisplatin and carboplatin-induced cytotoxicity in vivo without protecting tumor growth. Neoplasia, 2008, 10, 1105-1119.
    • (2008) Neoplasia , vol.10 , pp. 1105-1119
    • Das, B.1    Antoon, R.2    Tsuchida, R.3    Lotfi, S.4    Morozova, O.5    Farhat, W.6    Malkin, D.7    Koren, G.8    Yeger, H.9    Baruchel, S.10
  • 28
    • 3142722028 scopus 로고    scopus 로고
    • Deactivation of O2 Singlet Oxygen by Carotenoids, Internal Conversion of Excited Encounter Complexes
    • Schmidt, R. Deactivation of O2 Singlet Oxygen by Carotenoids, Internal Conversion of Excited Encounter Complexes. J Phy Chem A., 2004, 108, 5509-5513.
    • (2004) J Phy Chem A , vol.108 , pp. 5509-5513
    • Schmidt, R.1
  • 29
    • 0034102823 scopus 로고    scopus 로고
    • Degradation of Lycopene, ex-Carotene, and p-Carotene During Lipid Peroxidation
    • Anguelova, T.; Warthesen, J. Degradation of Lycopene, ex-Carotene, and p-Carotene During Lipid Peroxidation. J Food Sci., 2000, 65, 71-75.
    • (2000) J Food Sci , vol.65 , pp. 71-75
    • Anguelova, T.1    Warthesen, J.2
  • 30
    • 0000203065 scopus 로고    scopus 로고
    • Effects of Lutein, Lycopene, Annatto, and y-Tocopherol on Autoxidation of Triglycerides
    • Haila, K.M.; Lievonen, S.M.; Heinonen, M.I. Effects of Lutein, Lycopene, Annatto, and y-Tocopherol on Autoxidation of Triglycerides. J Agr Food Chem., 1996, 44, 2096-2100.
    • (1996) J Agr Food Chem , vol.44 , pp. 2096-2100
    • Haila, K.M.1    Lievonen, S.M.2    Heinonen, M.I.3
  • 31
    • 84858304101 scopus 로고    scopus 로고
    • Interactions of dietary carotenoids with activated (singlet) oxygen and free radicals. Potential effects for human health
    • Bohm, F.; Edge, R.; Truscott, G. Interactions of dietary carotenoids with activated (singlet) oxygen and free radicals. Potential effects for human health. Mol Nutr Food Res., 2012, 56, 205-216.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 205-216
    • Bohm, F.1    Edge, R.2    Truscott, G.3
  • 32
    • 0042905774 scopus 로고    scopus 로고
    • Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation in hairless mice
    • Gonzalez, S.; Astner, S.; An, W.; Goukassian, D.; Pathak, M.A. Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation in hairless mice. J Invest Dermatol, 2003, 121, 399-405.
    • (2003) J Invest Dermatol , vol.121 , pp. 399-405
    • Gonzalez, S.1    Astner, S.2    An, W.3    Goukassian, D.4    Pathak, M.A.5
  • 33
    • 34249868200 scopus 로고    scopus 로고
    • Vitamin E, antioxidant and nothing more
    • Traber, M.G.; Atkinson, J. Vitamin E, antioxidant and nothing more. Free Radic Biol Med., 2007, 43, 4-15.
    • (2007) Free Radic Biol Med , vol.43 , pp. 4-15
    • Traber, M.G.1    Atkinson, J.2
  • 34
    • 0037087203 scopus 로고    scopus 로고
    • Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice, role of peroxynitrite
    • Beharka, A.A.; Wu, D.; Serafini, M.; Meydani, S.N. Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice, role of peroxynitrite. Free Radic Biol Med., 2002, 32, 503-511.
    • (2002) Free Radic Biol Med , vol.32 , pp. 503-511
    • Beharka, A.A.1    Wu, D.2    Serafini, M.3    Meydani, S.N.4
  • 35
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E, function and metabolism
    • Brigelius-Flohe, R.; Traber, M.G. Vitamin E, function and metabolism. FASEB J., 1999, 13, 1145-1155.
    • (1999) FASEB J , vol.13 , pp. 1145-1155
    • Brigelius-Flohe, R.1    Traber, M.G.2
  • 37
    • 0023933505 scopus 로고
    • The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin
    • Wefers, H.; Sies, H. The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E. Eur J Biochem., 1988, 174, 353-357.
    • (1988) E. Eur J Biochem , vol.174 , pp. 353-357
    • Wefers, H.1    Sies, H.2
  • 38
    • 24044449234 scopus 로고    scopus 로고
    • Alpha-tocopherol, roles in prevention and therapy of human disease
    • Tucker, J.M.; Townsend, D.M. Alpha-tocopherol, roles in prevention and therapy of human disease. Biomed Pharmacother., 2005, 59, 380-387.
    • (2005) Biomed Pharmacother , vol.59 , pp. 380-387
    • Tucker, J.M.1    Townsend, D.M.2
  • 39
    • 0022695839 scopus 로고
    • Effect of selected oat sterols on the deterioration of heated soybean oil
    • White, P.; Armstrong, L. Effect of selected oat sterols on the deterioration of heated soybean oil. J Am Oil Chem Soc, 1986, 63, 525-529.
    • (1986) J Am Oil Chem Soc , vol.63 , pp. 525-529
    • White, P.1    Armstrong, L.2
  • 41
    • 3042736080 scopus 로고    scopus 로고
    • Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention
    • Mo, H.; Elson, C.E. Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. Exp Biol Med (Maywood)., 2004, 229, 567-585.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 567-585
    • Mo, H.1    Elson, C.E.2
  • 42
    • 0032868926 scopus 로고    scopus 로고
    • Isoprenoid-mediated inhibition of mevalonate synthesis, potential application to cancer
    • Elson, C.E.; Peffley, D.M.; Hentosh, P.; Mo, H. Isoprenoid-mediated inhibition of mevalonate synthesis, potential application to cancer. Proc Soc Exp Biol Med., 1999, 221, 294-311.
    • (1999) Proc Soc Exp Biol Med , vol.221 , pp. 294-311
    • Elson, C.E.1    Peffley, D.M.2    Hentosh, P.3    Mo, H.4
  • 43
    • 0031843397 scopus 로고    scopus 로고
    • Chemopreventive effect of squalene on colon cancer
    • Rao, C.V.; Newmark, H.L.; Reddy, B.S. Chemopreventive effect of squalene on colon cancer. Carcinogenesis, 1998, 19, 287-290.
    • (1998) Carcinogenesis , vol.19 , pp. 287-290
    • Rao, C.V.1    Newmark, H.L.2    Reddy, B.S.3
  • 44
    • 0031022932 scopus 로고    scopus 로고
    • Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors
    • Katdare, M.; Singhal, H.; Newmark, H.; Osborne, M.P.; Telang, N.T. Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors. Cancer Lett., 1997, 111, 141-147.
    • (1997) Cancer Lett , vol.111 , pp. 141-147
    • Katdare, M.1    Singhal, H.2    Newmark, H.3    Osborne, M.P.4    Telang, N.T.5
  • 45
    • 0031846030 scopus 로고    scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone-induced lung tumorigenesis by dietary olive oil and squalene
    • Smith, T.J.; Yang, G.Y.; Seril, D.N.; Liao, J.; Kim, S. Inhibition of 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone-induced lung tumorigenesis by dietary olive oil and squalene. Carcinogenesis, 1998, 19, 703-706.
    • (1998) Carcinogenesis , vol.19 , pp. 703-706
    • Smith, T.J.1    Yang, G.Y.2    Seril, D.N.3    Liao, J.4    Kim, S.5
  • 46
    • 0026621668 scopus 로고
    • Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis
    • Murakoshi, M.; Nishino, H.; Tokuda, H.; Iwashima, A.; Okuzumi, J.; Kitano, H.; Iwasaki, R. Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis. Int J Cancer., 1992, 52, 950-952.
    • (1992) Int J Cancer , vol.52 , pp. 950-952
    • Murakoshi, M.1    Nishino, H.2    Tokuda, H.3    Iwashima, A.4    Okuzumi, J.5    Kitano, H.6    Iwasaki, R.7
  • 47
    • 0017197097 scopus 로고
    • Cocarcinogenic and tumor-promoting agents in tobacco carcinogenesis
    • Van Duuren, B.L.; Goldschmidt, B.M.; Cocarcinogenic and tumor-promoting agents in tobacco carcinogenesis. J Natl Cancer Inst., 1976, 56, 1237-1242.
    • (1976) J Natl Cancer Inst , vol.56 , pp. 1237-1242
    • van Duuren, B.L.1    Goldschmidt, B.M.2
  • 48
    • 0034655467 scopus 로고    scopus 로고
    • Geranylgeranyl-Pyrophosphate, an Isoprenoid of Mevalonate Cascade, Is a Critical Compound for Rat Primary Cultured Cortical Neurons to Protect the Cell Death Induced by 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibition
    • Tanaka, T.; Tatsuno, I.; Uchida, D.; Moroo, I.; Morio, H.; Nakamura, S.; Noguchi, Y.; Yasuda, T.; Kitagawa, M.; Saito, Y.; Hirai, A. Geranylgeranyl-Pyrophosphate, an Isoprenoid of Mevalonate Cascade, Is a Critical Compound for Rat Primary Cultured Cortical Neurons to Protect the Cell Death Induced by 3-Hydroxy-3-Methylglutaryl-CoA Reductase Inhibition. The Journal of Neuroscience, 2000, 20, 2852-2859.
    • (2000) The Journal of Neuroscience , vol.20 , pp. 2852-2859
    • Tanaka, T.1    Tatsuno, I.2    Uchida, D.3    Moroo, I.4    Morio, H.5    Nakamura, S.6    Noguchi, Y.7    Yasuda, T.8    Kitagawa, M.9    Saito, Y.10    Hirai, A.11
  • 49
    • 0033561642 scopus 로고    scopus 로고
    • Activation of the transforming growth factor beta signaling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol
    • Ariazi, E.A.; Satomi, Y.; Ellis, M.J.; Haag, J.D.; Shi, W.; Sattler, C.A.; Gould, M.N. Activation of the transforming growth factor beta signaling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol. Cancer Res., 1999, 59, 1917-1928.
    • (1999) Cancer Res , vol.59 , pp. 1917-1928
    • Ariazi, E.A.1    Satomi, Y.2    Ellis, M.J.3    Haag, J.D.4    Shi, W.5    Sattler, C.A.6    Gould, M.N.7
  • 50
    • 0036827604 scopus 로고    scopus 로고
    • Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells
    • Carnesecchi, S.; Bradaia, A.; Fischer, B.; Coelho, D.; Scholler-Guinard, M.; Gosse, F.; Raul, F. Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells. J Pharmacol Exp Ther., 2002, 303, 711-715.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 711-715
    • Carnesecchi, S.1    Bradaia, A.2    Fischer, B.3    Coelho, D.4    Scholler-Guinard, M.5    Gosse, F.6    Raul, F.7
  • 51
    • 0034967914 scopus 로고    scopus 로고
    • Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells
    • Carnesecchi, S.; Schneider, Y.; Ceraline, J.; Duranton, B.; Gosse, F.; Seiler, N.; Raul, F. Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells. J Pharmacol Exp Ther., 2001, 298, 197-200.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 197-200
    • Carnesecchi, S.1    Schneider, Y.2    Ceraline, J.3    Duranton, B.4    Gosse, F.5    Seiler, N.6    Raul, F.7
  • 52
    • 70949104196 scopus 로고    scopus 로고
    • Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74
    • Jesch, E.D.; Seo, J.M.; Carr, T.P.; Lee, J.Y. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells. Nutr Res., 2009, 29, 859-866.
    • (2009) Int Cells. Nutr Res , vol.29 , pp. 859-866
    • Jesch, E.D.1    Seo, J.M.2    Carr, T.P.3    Lee, J.Y.4
  • 53
    • 0036325649 scopus 로고    scopus 로고
    • Increased intestinal ABCA1 expression contributes to the decrease in cholesterol absorption after plant stanol consumption
    • Plat, J.; Mensink, R.P. Increased intestinal ABCA1 expression contributes to the decrease in cholesterol absorption after plant stanol consumption. FASEB J., 2002, 16, 1248-1253.
    • (2002) FASEB J , vol.16 , pp. 1248-1253
    • Plat, J.1    Mensink, R.P.2
  • 54
    • 33947380185 scopus 로고    scopus 로고
    • Regulation of intestinal cholesterol absorption
    • Wang, D.Q. Regulation of intestinal cholesterol absorption. Annu Rev Physiol., 2007, 69, 221-248.
    • (2007) Annu Rev Physiol , vol.69 , pp. 221-248
    • Wang, D.Q.1
  • 55
    • 0033851608 scopus 로고    scopus 로고
    • Phytosterols as Anticancer Dietary Components, Evidence and Mechanism of Action
    • Awad, A.B.; Fink, C.S. Phytosterols as Anticancer Dietary Components, Evidence and Mechanism of Action. J Nutr., 2000, 130, 2127-2130.
    • (2000) J Nutr , vol.130 , pp. 2127-2130
    • Awad, A.B.1    Fink, C.S.2
  • 56
    • 0032906518 scopus 로고    scopus 로고
    • The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners, inhibition of post marathon immune suppression and inflammation
    • Bouic, P.J.; Clark, A.; Lamprecht, J.; Freestone, M.; Pool, E.J.; Liebenberg, R.W.; Kotze, D.; van Jaarsveld, P.P. The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners, inhibition of post marathon immune suppression and inflammation. Int J Sports Med., 1999, 20, 258-262.
    • (1999) Int J Sports Med , vol.20 , pp. 258-262
    • Bouic, P.J.1    Clark, A.2    Lamprecht, J.3    Freestone, M.4    Pool, E.J.5    Liebenberg, R.W.6    Kotze, D.7    van Jaarsveld, P.P.8
  • 57
    • 26444588691 scopus 로고    scopus 로고
    • Antiatherogenic effects of dietary plant sterols are associated with inhibition of proinflammatory cytokine production in Apo E-KO mice
    • Nashed, B.; Yeganeh, B.; Hay Glass, K.T.; Moghadasian, M.H. Antiatherogenic effects of dietary plant sterols are associated with inhibition of proinflammatory cytokine production in Apo E-KO mice. J Nutr., 2005, 135, 2438-2444.
    • (2005) J Nutr , vol.135 , pp. 2438-2444
    • Nashed, B.1    Yeganeh, B.2    Hay Glass, K.T.3    Moghadasian, M.H.4
  • 58
    • 0142169324 scopus 로고    scopus 로고
    • Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7
    • Moreno, J.J. Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7. Free Radic Biol Med., 2003, 35, 1073-1081.
    • (2003) Free Radic Biol Med , vol.35 , pp. 1073-1081
    • Moreno, J.J.1
  • 59
    • 19544371395 scopus 로고    scopus 로고
    • Beta-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages
    • Vivancos, M.; Moreno, J.J. beta-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages. Free Radic Biol Med., 2005, 39, 91-97.
    • (2005) Free Radic Biol Med , vol.39 , pp. 91-97
    • Vivancos, M.1    Moreno, J.J.2
  • 60
    • 0035860643 scopus 로고    scopus 로고
    • Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens
    • Gutendorf, B.; Westendorf, J. Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology, 2001, 166, 79-89.
    • (2001) Toxicology , vol.166 , pp. 79-89
    • Gutendorf, B.1    Westendorf, J.2
  • 61
    • 34547429099 scopus 로고    scopus 로고
    • Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines
    • Newill, H.; Loske, R.; Wagner, J.; Johannes, C.; Lorenz, R.L, Lehmann, L. Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines. Mol Nutr Food Res., 2007, 51, 888-898.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 888-898
    • Newill, H.1    Loske, R.2    Wagner, J.3    Johannes, C.4    Lorenz, R.L.5    Lehmann, L.6
  • 62
    • 77949460855 scopus 로고    scopus 로고
    • The effects of pomegranate seed extract and beta-sitosterol on rat uterine contractions
    • Promprom, W.; Kupittayanant, P.; Indrapichate, K.; Wray, S.; Kupittayanant, S. The effects of pomegranate seed extract and beta-sitosterol on rat uterine contractions. Reprod Sci., 2009, 17, 288-296.
    • (2009) Reprod Sci , vol.17 , pp. 288-296
    • Promprom, W.1    Kupittayanant, P.2    Indrapichate, K.3    Wray, S.4    Kupittayanant, S.5
  • 63
    • 0018872473 scopus 로고
    • Protective effect of plant sterols against chemically induced colon tumors in rats
    • Raicht, R.F.; Cohen, B.I.; Fazzini, E.P.; Sarwal A.N.; Takahashi, M. Protective effect of plant sterols against chemically induced colon tumors in rats. Cancer Res., 1980, 40, 403-405.
    • (1980) Cancer Res , vol.40 , pp. 403-405
    • Raicht, R.F.1    Cohen, B.I.2    Fazzini, E.P.3    Sarwal, A.N.4    Takahashi, M.5
  • 64
    • 0029966199 scopus 로고    scopus 로고
    • Beta-Sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids
    • Awad, A.B.; Chen, Y.C.; Fink, C.S.; Hennessey, T. beta-Sitosterol inhibits HT-29 human colon cancer cell growth and alters membrane lipids. Anticancer Res., 1996, 16, 2797-2804.
    • (1996) Anticancer Res , vol.16 , pp. 2797-2804
    • Awad, A.B.1    Chen, Y.C.2    Fink, C.S.3    Hennessey, T.4
  • 65
    • 0034185334 scopus 로고    scopus 로고
    • Inhibition of growth and stimulation of apoptosis by beta-sitosterol treatment of MDA-MB-231 human breast cancer cells in culture
    • Awad, A.B.; Downie, A.C.; Fink, C.S. Inhibition of growth and stimulation of apoptosis by beta-sitosterol treatment of MDA-MB-231 human breast cancer cells in culture. Int J Mol Med., 2000, 5, 541-545.
    • (2000) Int J Mol Med , vol.5 , pp. 541-545
    • Awad, A.B.1    Downie, A.C.2    Fink, C.S.3
  • 66
    • 0031742610 scopus 로고    scopus 로고
    • Beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells
    • von Holtz, R.L.; Fink, C.S.; Awad, A.B. beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells. Nutr Cancer., 1998, 32, 8-12.
    • (1998) Nutr Cancer , vol.32 , pp. 8-12
    • von Holtz, R.L.1    Fink, C.S.2    Awad, A.B.3
  • 67
    • 34250213261 scopus 로고    scopus 로고
    • Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells
    • Moon, D.O.; Lee, K.J.; Choi, Y.H.; Kim, G.Y. Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells. Int Immunopharmacol., 2007, 7, 1044-1053.
    • (2007) Int Immunopharmacol , vol.7 , pp. 1044-1053
    • Moon, D.O.1    Lee, K.J.2    Choi, Y.H.3    Kim, G.Y.4
  • 68
    • 42749090904 scopus 로고    scopus 로고
    • Beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways
    • Moon, D-O.; Kim, M-O.; Choi, YH.; Kim, G-Y. beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Cancer Lett., 2008, 264, 181-191.
    • (2008) Cancer Lett , vol.264 , pp. 181-191
    • Moon, D.-O.1    Kim, M.-O.2    Choi, Y.H.3    Kim, G.-Y.4
  • 69
    • 34447115675 scopus 로고    scopus 로고
    • Beta-Sitosterol Induces Anti-proliferation and Apoptosis in Human Leukemic U937 Cells through Activation of Caspase-3 and Induction of Bax/Bcl-2 Ratio
    • Park, C.; Moon, D-O.; Rhu, C-H.; Choi, B.T.; Lee, W.H.; Kim, G-Y.; Choi, Y.H. beta-Sitosterol Induces Anti-proliferation and Apoptosis in Human Leukemic U937 Cells through Activation of Caspase-3 and Induction of Bax/Bcl-2 Ratio. Biological and Pharmaceutical Bulletin. 2007, 30, 1317-1323.
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , pp. 1317-1323
    • Park, C.1    Moon, D.-O.2    Rhu, C.-H.3    Choi, B.T.4    Lee, W.H.5    Kim, G.-Y.6    Choi, Y.H.7
  • 71
    • 79960053725 scopus 로고    scopus 로고
    • Beyond cholesterol-lowering effects of plant sterols, clinical and experimental evidence of anti-inflammatory properties
    • Othman, R.A.; Moghadasiian, M.H. Beyond cholesterol-lowering effects of plant sterols, clinical and experimental evidence of anti-inflammatory properties. Nutr Rev., 2011, 69, 371-382.
    • (2011) Nutr Rev , vol.69 , pp. 371-382
    • Othman, R.A.1    Moghadasiian, M.H.2
  • 72
    • 78649757010 scopus 로고    scopus 로고
    • Suppression of ovalbumin-induced Th2-driven airway inflammation by beta-sitosterol in a guinea pig model of asthma
    • Mahajan, S.G.; Mehta, A.A. Suppression of ovalbumin-induced Th2-driven airway inflammation by beta-sitosterol in a guinea pig model of asthma. Eur J Pharmacol,; 2011, 650, 458-464.
    • (2011) Eur J Pharmacol , vol.650 , pp. 458-464
    • Mahajan, S.G.1    Mehta, A.A.2
  • 73
    • 77951089588 scopus 로고    scopus 로고
    • Beta-sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells
    • Loizou, S.; Lekakis, I.; Chrousos, G.P.; Moutsatsou, P. Beta-sitosterol exhibits anti-inflammatory activity in human aortic endothelial cells. Mol Nutr Food Res., 2010, 54, 551-558.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 551-558
    • Loizou, S.1    Lekakis, I.2    Chrousos, G.P.3    Moutsatsou, P.4
  • 74
    • 84860388971 scopus 로고    scopus 로고
    • Beta-Sitosterol down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in J774A.1 murine macrophages
    • Valerio, M.; Awad, A.B. beta-Sitosterol down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in J774A.1 murine macrophages. Int Immunopharmacol., 2011, 11, 1012-1017.
    • (2011) Int Immunopharmacol , vol.11 , pp. 1012-1017
    • Valerio, M.1    Awad, A.B.2
  • 76
    • 0024378310 scopus 로고
    • Fatty acid desaturase activities are modulated by phytosterol incorporation in microsomes
    • Leikin, A.I.; Brenner, R.R.; Fatty acid desaturase activities are modulated by phytosterol incorporation in microsomes. Biochim Biophys Acta., 1989, 1005, 187-191.
    • (1989) Biochim Biophys Acta , vol.1005 , pp. 187-191
    • Leikin, A.I.1    Brenner, R.R.2
  • 77
    • 0028325325 scopus 로고
    • Effects of Stinging Nettle Root Extracts and Their Steroidal Components on the Na+, K+-ATPase of the Benign Prostatic Hyperplasia1
    • Hirano, T.; Homma, M.; Oka, K. Effects of Stinging Nettle Root Extracts and Their Steroidal Components on the Na+, K+-ATPase of the Benign Prostatic Hyperplasia1. Planta Med., 1994, 60, 30-33.
    • (1994) Planta Med , vol.60 , pp. 30-33
    • Hirano, T.1    Homma, M.2    Oka, K.3
  • 78
    • 0031775406 scopus 로고    scopus 로고
    • Phytosterol feeding induces alteration in testosterone metabolism in rat tissues
    • Awad, A.B.; Hartati, M.S.; Fink, C.S. Phytosterol feeding induces alteration in testosterone metabolism in rat tissues. J Nutri Biochem., 1998, 9, 712-717.
    • (1998) J Nutri Biochem , vol.9 , pp. 712-717
    • Awad, A.B.1    Hartati, M.S.2    Fink, C.S.3
  • 79
    • 0031921948 scopus 로고    scopus 로고
    • Beta-Sitosterol inhibits growth of HT-29 human colon cancer cells by activating the sphingomyelin cycle
    • Awad, A.B.; von Holtz, R.L.; Cone, J.P.; Fink, C.S.; Chen, Y.C. beta-Sitosterol inhibits growth of HT-29 human colon cancer cells by activating the sphingomyelin cycle. Anticancer Res., 1998, 18, 471-473.
    • (1998) Anticancer Res , vol.18 , pp. 471-473
    • Awad, A.B.1    von Holtz, R.L.2    Cone, J.P.3    Fink, C.S.4    Chen, Y.C.5
  • 80
    • 0141481039 scopus 로고    scopus 로고
    • Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist
    • Kaneko, E.; Matsuda, M.; Yamada, Y.; Tachibana, Y.; Shimomura, I.; Makishima, M.; Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. J Biol Chem., 2003, 278, 36091-36098.
    • (2003) J Biol Chem , vol.278 , pp. 36091-36098
    • Kaneko, E.1    Matsuda, M.2    Yamada, Y.3    Tachibana, Y.4    Shimomura, I.5    Makishima, M.6
  • 81
    • 77956188489 scopus 로고    scopus 로고
    • Molecular and dietary regulation of beta {ogonek}beta-carotene 15,15'-monooxygenase 1 (BCMO1)
    • Lietz, G.; Lange, J.; Rimbach, G. Molecular and dietary regulation of beta {ogonek}beta-carotene 15,15'-monooxygenase 1 (BCMO1). Arch Biochem Biophys, 2010, 502, 8-16.
    • (2010) Arch Biochem Biophys , vol.502 , pp. 8-16
    • Lietz, G.1    Lange, J.2    Rimbach, G.3
  • 82
    • 66849101522 scopus 로고    scopus 로고
    • Function of retinoic acid receptors during embryonic development
    • Mark, M.; Ghyselinck, N.B.; Chambon, P. Function of retinoic acid receptors during embryonic development. Nucl Recept Signal., 2009, 7, e002.
    • (2009) Nucl Recept Signal , vol.7
    • Mark, M.1    Ghyselinck, N.B.2    Chambon, P.3
  • 86
    • 0037015035 scopus 로고    scopus 로고
    • Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
    • Dinkova-Kostova, A.T.; Holtzclaw, W.D.; Cole, R.N.; Itoh, K.; Wakabayashi, N.; Katoh, Y.; Yamamoto, M.; Talalay, P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. P Natl A Sci, 2002, 99, 11908-11913.
    • (2002) P Natl a Sci , vol.99 , pp. 11908-11913
    • Dinkova-Kostova, A.T.1    Holtzclaw, W.D.2    Cole, R.N.3    Itoh, K.4    Wakabayashi, N.5    Katoh, Y.6    Yamamoto, M.7    Talalay, P.8
  • 87
    • 75149149494 scopus 로고    scopus 로고
    • Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15'-monooxygenase
    • Poliakov, E.; Gentleman, S.; Chander, P.; Cunningham, F.X.Jr.; Grigorenko, B.L.; Nemuhin, A.V.; Redmond, T.M. Biochemical evidence for the tyrosine involvement in cationic intermediate stabilization in mouse beta-carotene 15, 15'-monooxygenase. BMC Biochem., 2009, 10, 31.
    • (2009) BMC Biochem , vol.10 , pp. 31
    • Poliakov, E.1    Gentleman, S.2    Chander, P.3    Cunningham Jr., F.X.4    Grigorenko, B.L.5    Nemuhin, A.V.6    Redmond, T.M.7
  • 89
    • 83255186681 scopus 로고
    • Mammalian Carotenoid-oxygenases, Key players for carotenoid function and homeostasis
    • Lobo, G.P.; Amengual, J.; Palczewski, G.; Babino, D.; von Lintig J. Mammalian Carotenoid-oxygenases, Key players for carotenoid function and homeostasis. Biochim Biophys Acta., 2012, 1821, 78-87.
    • (1821) Biochim Biophys Acta , vol.2012 , pp. 78-87
    • Lobo, G.P.1    Amengual, J.2    Palczewski, G.3    Babino, D.4    von Lintig, J.5
  • 91
    • 34548142633 scopus 로고    scopus 로고
    • Beta-carotene inhibits tumor-specific angiogenesis by altering the cytokine profile and inhibits the nuclear translocation of transcription factors in B16F-10 melanoma cells
    • Guruvayoorappan, C; Kuttan, G. Beta-carotene inhibits tumor-specific angiogenesis by altering the cytokine profile and inhibits the nuclear translocation of transcription factors in B16F-10 melanoma cells. Integr Cancer Ther., 2007, 6, 258-270.
    • (2007) Integr Cancer Ther , vol.6 , pp. 258-270
    • Guruvayoorappan, C.1    Kuttan, G.2
  • 92
    • 36749049202 scopus 로고    scopus 로고
    • Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells
    • Kalariya, N.M.; Ramana, K.V.; Srivastava, S.K.; van Kuijk, F.J. Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Exp Eye Res., 2008, 86, 70-80.
    • (2008) Exp Eye Res , vol.86 , pp. 70-80
    • Kalariya, N.M.1    Ramana, K.V.2    Srivastava, S.K.3    van Kuijk, F.J.4
  • 93
    • 0027979264 scopus 로고
    • Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors
    • La Rosa, F.A.; Pierce, J.W.; Sonenshein, G.E. Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors. Mol Cell Biol, 1994, 14, 1039-1044.
    • (1994) Mol Cell Biol , vol.14 , pp. 1039-1044
    • la Rosa, F.A.1    Pierce, J.W.2    Sonenshein, G.E.3
  • 95
    • 0037312590 scopus 로고    scopus 로고
    • Beta-carotene regulates NF-kappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells
    • Palozza, P.; Serini, S.; Torsello, A.; Di Nicuolo, F.; Piccioni, E.; Ubaldi, V.; Pioli, C; Wolf F.I.; Calviello, G. Beta-carotene regulates NF-kappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells. J Nutr., 2003, 133, 381-388.
    • (2003) J Nutr , vol.133 , pp. 381-388
    • Palozza, P.1    Serini, S.2    Torsello, A.3    Di Nicuolo, F.4    Piccioni, E.5    Ubaldi, V.6    Pioli, C.7    Wolf, F.I.8    Calviello, G.9
  • 96
    • 4344570628 scopus 로고    scopus 로고
    • Beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate
    • Palozza, P.; Serini, S.; Di Nicuolo, F.; Boninsegna, A.; Torsello, A.; Maggiano, N.; Ranelletti, F.O.; Wolf, F.I.; Calviello, G.; Cittadini, A.; beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate. Carcinogenesis. 2004, 25, 1315-1325.
    • (2004) Carcinogenesis , vol.25 , pp. 1315-1325
    • Palozza, P.1    Serini, S.2    Di Nicuolo, F.3    Boninsegna, A.4    Torsello, A.5    Maggiano, N.6    Ranelletti, F.O.7    Wolf, F.I.8    Calviello, G.9    Cittadini, A.10
  • 97
    • 0035341998 scopus 로고    scopus 로고
    • Beta-carotene at high concentrations induces apoptosis by enhancing oxy-radical production in human adenocarcinoma cells
    • Palozza, P.; Calviello, G.; Serini, S.; Maggiano, N.; Lanza, P.; Ranelletti, F.O.; Bartoli, G.M. beta-carotene at high concentrations induces apoptosis by enhancing oxy-radical production in human adenocarcinoma cells. Free Radic Biol Med., 2001, 30, 1000-1007.
    • (2001) Free Radic Biol Med , vol.30 , pp. 1000-1007
    • Palozza, P.1    Calviello, G.2    Serini, S.3    Maggiano, N.4    Lanza, P.5    Ranelletti, F.O.6    Bartoli, G.M.7
  • 98
    • 0037050725 scopus 로고    scopus 로고
    • Regulation of cell cycle progression and apoptosis by beta-carotene in undifferentiated and differentiated HL-60 leukemia cells, possible involvement of a redox mechanism
    • Palozza, P.; Serini, S.; Torsello, A.; Boninsegna, A.; Covacci, V.; Maggiano, N.; Ranelletti, F.O.; Wolf F.I.; Calviello, G. Regulation of cell cycle progression and apoptosis by beta-carotene in undifferentiated and differentiated HL-60 leukemia cells, possible involvement of a redox mechanism. Int J Cancer., 2002, 97, 593-600.
    • (2002) Int J Cancer , vol.97 , pp. 593-600
    • Palozza, P.1    Serini, S.2    Torsello, A.3    Boninsegna, A.4    Covacci, V.5    Maggiano, N.6    Ranelletti, F.O.7    Wolf, F.I.8    Calviello, G.9
  • 99
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy, crossing the threshold
    • Fisher, D.E. Apoptosis in cancer therapy, crossing the threshold. Cell, 1994, 78, 539-542.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 100
    • 0034494960 scopus 로고    scopus 로고
    • Modulation of cell-cell communication in the cause and chemoprevention/chemotherapy of cancer
    • Trosko, J.E.; Chang, C.C. Modulation of cell-cell communication in the cause and chemoprevention/chemotherapy of cancer. Biofactors, 2000, 12, 259-263.
    • (2000) Biofactors , vol.12 , pp. 259-263
    • Trosko, J.E.1    Chang, C.C.2
  • 101
    • 0032100446 scopus 로고    scopus 로고
    • Caspase Activation Is Required for Nitric Oxide-Mediated, CD95(APO-1/Fas)-Dependent and Independent Apoptosis in Human Neoplastic Lymphoid Cells
    • Chlichlia, K.; Peter, M.E.; Rocha, M.; Scaffidi, C; Bucur, M.; Krammer, P.H.; Schirrmacher, V.; Umansky, V. Caspase Activation Is Required for Nitric Oxide-Mediated, CD95(APO-1/Fas)-Dependent and Independent Apoptosis in Human Neoplastic Lymphoid Cells. Blood, 1998, 91, 4311-4320.
    • (1998) Blood , vol.91 , pp. 4311-4320
    • Chlichlia, K.1    Peter, M.E.2    Rocha, M.3    Scaffidi, C.4    Bucur, M.5    Krammer, P.H.6    Schirrmacher, V.7    Umansky, V.8
  • 102
    • 84856596398 scopus 로고    scopus 로고
    • A Naturally Occurring Carotenoid, Lutein, Reduces PDGF and H2O2 Signaling and Compromised Migration in Cultured Vascular Smooth Muscle Cells
    • Lo, H.M.; Tsai, Y.J.; Du, W.Y.; Tsou, C.J.; Wu, W.B. A Naturally Occurring Carotenoid, Lutein, Reduces PDGF and H2O2 Signaling and Compromised Migration in Cultured Vascular Smooth Muscle Cells. J Biomed Sci., 2012, 19, 18.
    • (2012) J Biomed Sci , vol.19 , pp. 18
    • Lo, H.M.1    Tsai, Y.J.2    Du, W.Y.3    Tsou, C.J.4    Wu, W.B.5
  • 103
    • 0032522865 scopus 로고    scopus 로고
    • Alpha- and delta-tocopherol induce expression of hepatic alpha-tocopherol-transfer-protein mRNA
    • Fechner, H.; Schlame, M.; Guthmann, F.; Stevens, P.A.; Rustow, B. alpha- and delta-tocopherol induce expression of hepatic alpha-tocopherol-transfer-protein mRNA. Biochem J., 1998, 331, 577-581.
    • (1998) Biochem J , vol.331 , pp. 577-581
    • Fechner, H.1    Schlame, M.2    Guthmann, F.3    Stevens, P.A.4    Rustow, B.5
  • 104
    • 0037157196 scopus 로고    scopus 로고
    • Non-antioxidant molecular functions of alpha-tocopherol (vitamin E)
    • Azzi, A.; Ricciarelli, R.; Zingg, J.M. Non-antioxidant molecular functions of alpha-tocopherol (vitamin E). FEBS Lett, 2002, 519, 8-10.
    • (2002) FEBS Lett , vol.519 , pp. 8-10
    • Azzi, A.1    Ricciarelli, R.2    Zingg, J.M.3
  • 106
    • 77952318884 scopus 로고    scopus 로고
    • The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation
    • Johnson, K.G.; Kornfeld, K. The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation. Dev Biol, 2010, 341, 464-471.
    • (2010) Dev Biol , vol.341 , pp. 464-471
    • Johnson, K.G.1    Kornfeld, K.2
  • 107
    • 0032528866 scopus 로고    scopus 로고
    • Alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state
    • Ricciarelli, R.; Tasinato, A.; Clement, S.; Ozer, N.K.; Boscoboinik, D.; Azzi, A. Alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. Biochem J., 1998, 334, 243-249.
    • (1998) Biochem J , vol.334 , pp. 243-249
    • Ricciarelli, R.1    Tasinato, A.2    Clement, S.3    Ozer, N.K.4    Boscoboinik, D.5    Azzi, A.6
  • 109
    • 0029846809 scopus 로고    scopus 로고
    • Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism
    • Freedman, J.E.; Farhat, J.H.; Loscalzo, J.; Keaney, J.F. Jr. Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism. Circulation, 1996, 94, 2434-2440.
    • (1996) Circulation , vol.94 , pp. 2434-2440
    • Freedman, J.E.1    Farhat, J.H.2    Loscalzo, J.3    Keaney Jr., J.F.4
  • 111
    • 0032446835 scopus 로고    scopus 로고
    • Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells
    • Martin-Nizard, F.; Boullier, A.; Fruchart, J.C.; Duriez, P. Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells. J Cardiovasc Risk., 1998, 5, 339-345.
    • (1998) J Cardiovasc Risk , vol.5 , pp. 339-345
    • Martin-Nizard, F.1    Boullier, A.2    Fruchart, J.C.3    Duriez, P.4
  • 112
    • 0035150318 scopus 로고    scopus 로고
    • The effect of alpha-tocopherol on monocyte proatherogenic activity
    • Jialal, I.; Devaraj, S.; Kaul, N. The effect of alpha-tocopherol on monocyte proatherogenic activity. J Nutr., 2001, 131, 389S-394S.
    • (2001) J Nutr , vol.131
    • Jialal, I.1    Devaraj, S.2    Kaul, N.3
  • 113
    • 0032740397 scopus 로고    scopus 로고
    • Effect of vitamin E on human aortic endothelial cell production of chemokines and adhesion to monocytes
    • Wu, D.; Koga, T.; Martin, K.R.; Meydani, M. Effect of vitamin E on human aortic endothelial cell production of chemokines and adhesion to monocytes. Atherosclerosis, 1999, 147, 297-307.
    • (1999) Atherosclerosis , vol.147 , pp. 297-307
    • Wu, D.1    Koga, T.2    Martin, K.R.3    Meydani, M.4
  • 115
    • 0037428174 scopus 로고    scopus 로고
    • Alpha-tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-alpha-mediated downregulation in human smooth muscle cells
    • Villacorta, L.; Graca-Souza, A.V.; Ricciarelli, R.; Zingg, J.M.; Azzi, A. Alpha-tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-alpha-mediated downregulation in human smooth muscle cells. Circ Res., 2003, 92, 104-110.
    • (2003) Circ Res , vol.92 , pp. 104-110
    • Villacorta, L.1    Graca-Souza, A.V.2    Ricciarelli, R.3    Zingg, J.M.4    Azzi, A.5
  • 117
    • 0031912986 scopus 로고    scopus 로고
    • Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2
    • Grau, A.; Ortiz, A. Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2. Chem Phys Lipids., 1998, 91, 109-118.
    • (1998) Chem Phys Lipids , vol.91 , pp. 109-118
    • Grau, A.1    Ortiz, A.2
  • 118
    • 0036296032 scopus 로고    scopus 로고
    • First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation, crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution
    • Chandra, V.; Jasti, J.; Kaur, P.; Betzel, C.; Srinivasan, A.; Singh, T.P. First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation, crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution. J Mol Biol., 2002, 320, 215-222.
    • (2002) J Mol Biol , vol.320 , pp. 215-222
    • Chandra, V.1    Jasti, J.2    Kaur, P.3    Betzel, C.4    Srinivasan, A.5    Singh, T.P.6
  • 119
    • 0033043778 scopus 로고    scopus 로고
    • Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols
    • Yu, W.; Simmons-Menchaca, M.; Gapor, A.; Sanders, B.G.; Kline, K. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. Nutr Cancer., 1999, 33, 26-32.
    • (1999) Nutr Cancer , vol.33 , pp. 26-32
    • Yu, W.1    Simmons-Menchaca, M.2    Gapor, A.3    Sanders, B.G.4    Kline, K.5
  • 122
    • 0037427539 scopus 로고    scopus 로고
    • Succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery
    • Ni, J.; Chen, M.; Zhang, Y.; Li, R.; Huang, J.; Yeh, S. Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery. Biochem Biophys Res Commun., 2003, 300, 357-363.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 357-363
    • Ni, J.1    Chen, M.2    Zhang, Y.3    Li, R.4    Huang, J.5    Yeh, S.6    Vitamin, E.7
  • 123
    • 33646077406 scopus 로고    scopus 로고
    • Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Numakawa, Y.; Numakawa, T.; Matsumoto, T.; Yagasaki, Y.; Kumamaru, E.; Kunugi, H.; Taguchi, T.; Niki, E. Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J Neurochem., 2006, 97, 1191-1202.
    • (2006) J Neurochem , vol.97 , pp. 1191-1202
    • Numakawa, Y.1    Numakawa, T.2    Matsumoto, T.3    Yagasaki, Y.4    Kumamaru, E.5    Kunugi, H.6    Taguchi, T.7    Niki, E.8
  • 124
    • 33644891347 scopus 로고    scopus 로고
    • Tocotrienols, Vitamin E beyond tocopherols
    • Sen, C.K.; Khanna, S.; Roy, S. Tocotrienols, Vitamin E beyond tocopherols. Life Sci., 2006, 78, 2088-2098.
    • (2006) Life Sci , vol.78 , pp. 2088-2098
    • Sen, C.K.1    Khanna, S.2    Roy, S.3
  • 125
    • 35649015179 scopus 로고    scopus 로고
    • Alpha-Tocopherol Inhibits the Respiratory Burst in Human Monocytes. Journal of Biological Chemistry 1998, 273, 32801-32805. The orphan receptor GPR55 is a novel cannabinoid receptor
    • Ryberg, E.; Alpha-Tocopherol Inhibits the Respiratory Burst in Human Monocytes. Journal of Biological Chemistry 1998, 273, 32801-32805. The orphan receptor GPR55 is a novel cannabinoid receptor. Brit J Pharmacol, 2007, 152, 1092-1101.
    • (2007) Brit J Pharmacol , vol.152 , pp. 1092-1101
    • Ryberg, E.1
  • 126
    • 21644456607 scopus 로고    scopus 로고
    • Signal transduction activated by cannabinoid receptors
    • Diaz-Laviada, I.; Ruiz-Llorente, L. Signal transduction activated by cannabinoid receptors. Mini Rev Med Chem., 2005, 5, 619-630.
    • (2005) Mini Rev Med Chem , vol.5 , pp. 619-630
    • Diaz-Laviada, I.1    Ruiz-Llorente, L.2
  • 127
    • 77954177664 scopus 로고    scopus 로고
    • Cannabinoids and the immune system, an overview
    • Tanasescu, R.; Constantinescu, C.S. Cannabinoids and the immune system, an overview. Immunobiology, 2010, 215, 588-597.
    • (2010) Immunobiology , vol.215 , pp. 588-597
    • Tanasescu, R.1    Constantinescu, C.S.2


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