-
1
-
-
0029945201
-
β-carotene, carotenoids, and disease prevention in humans
-
Mayne, S. T. (1996) β-Carotene, carotenoids, and disease prevention in humans. FASEB J. 10: 690-701.
-
(1996)
FASEB J.
, vol.10
, pp. 690-701
-
-
Mayne, S.T.1
-
2
-
-
0028987719
-
β-carotene, vitamin E and vitamin C in different stages of experimental carcinogenesis
-
Gerster H. (1995) β-Carotene, vitamin E and vitamin C in different stages of experimental carcinogenesis. Eur. J. Clin. Nutr. 49: 155-168.
-
(1995)
Eur. J. Clin. Nutr.
, vol.49
, pp. 155-168
-
-
Gerster, H.1
-
3
-
-
9244262406
-
Effects of a combination of β-carotene and vitamin A on lung cancer and cardiovascular disease
-
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Jr., Valanis, B., Williams, J. H., Jr., Barnhart, S. & Hammar, S. (1996) Effects of a combination of β-carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 334: 1150-1155.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1150-1155
-
-
Omenn, G.S.1
Goodman, G.E.2
Thornquist, M.D.3
Balmes, J.4
Cullen, M.R.5
Glass, A.6
Keogh, J.P.7
Meyskens F.L., Jr.8
Valanis, B.9
Williams J.H., Jr.10
Barnhart, S.11
Hammar, S.12
-
4
-
-
0038692733
-
Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial
-
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Jr., Valanis, B., Williams, J. H., Jr., Barnhart, S. & Hammar, S. (1996) Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J. Natl. Cancer Inst. 88: 1550-1559.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1550-1559
-
-
Omenn, G.S.1
Goodman, G.E.2
Thornquist, M.D.3
Balmes, J.4
Cullen, M.R.5
Glass, A.6
Keogh, J.P.7
Meyskens F.L., Jr.8
Valanis, B.9
Williams J.H., Jr.10
Barnhart, S.11
Hammar, S.12
-
5
-
-
0010607277
-
The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers
-
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. (1994) The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 330: 1029-1035.
-
(1994)
N. Engl. J. Med
, vol.330
, pp. 1029-1035
-
-
-
6
-
-
0029956537
-
β-carotene and lung cancer promotion in heavy smokers - A plausible relationship?
-
Mayne, S. T., Handelman, G. J. & Beecher, G. (1996) β-Carotene and lung cancer promotion in heavy smokers - a plausible relationship? J. Natl. Cancer Inst. 88: 1513-1515.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1513-1515
-
-
Mayne, S.T.1
Handelman, G.J.2
Beecher, G.3
-
7
-
-
0033528079
-
Retinoid signaling and activator protein-1 expression in ferrets given β-carotene supplements and exposed to tobacco smoke
-
Wang, X. D., Liu, C., Bronson, R. T., Smith, D. E., Krinsky, N. I. & Russell, R. M. (1999) Retinoid signaling and Activator Protein-1 expression in ferrets given β-carotene supplements and exposed to tobacco smoke. J. Natl. Cancer Inst. 91: 60-66.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 60-66
-
-
Wang, X.D.1
Liu, C.2
Bronson, R.T.3
Smith, D.E.4
Krinsky, N.I.5
Russell, R.M.6
-
8
-
-
0036137616
-
Mitogenic and apoptotic signaling by carotenoids: Involvement of a redox mechanism
-
Palozza, P., Serini, S., Di Nicuolo, F. & Calviello, G. (2001) Mitogenic and apoptotic signaling by carotenoids: involvement of a redox mechanism. IUBMB Life 52: 1-5.
-
(2001)
IUBMB Life
, vol.52
, pp. 1-5
-
-
Palozza, P.1
Serini, S.2
Di Nicuolo, F.3
Calviello, G.4
-
9
-
-
0035341998
-
β-carotene at high concentrations induces apoptosis by enhancing oxy-radical production in human adenocarcinoma cells
-
Palozza, P., Calviello, G., Serini, S., Maggiano, N., Lanza, P., Ranelletti, F. O. & Bartoli, G. M. (2001) β-Carotene at high concentrations induces apoptosis by enhancing oxy-radical production in human adenocarcinoma cells. Free Radic. Biol. Med. 30: 1000-1007.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 1000-1007
-
-
Palozza, P.1
Calviello, G.2
Serini, S.3
Maggiano, N.4
Lanza, P.5
Ranelletti, F.O.6
Bartoli, G.M.7
-
10
-
-
0037050725
-
Regulation of cell cycle progression and apoptosis by β-carotene in undifferentiated and differentiated HL-60 leukemia cells: Possible involvement of a redox mechanism
-
Palozza, P., Serini, S., Torsello, A., Boninsegna, A., Covacci, V., Maggiano, M., Ranelletti, F. O., Wolf, F. I. & Calviello, G. (2002) Regulation of cell cycle progression and apoptosis by β-carotene in undifferentiated and differentiated HL-60 leukemia cells: possible involvement of a redox mechanism. Int. J. Cancer 97: 593-600.
-
(2002)
Int. J. Cancer
, vol.97
, pp. 593-600
-
-
Palozza, P.1
Serini, S.2
Torsello, A.3
Boninsegna, A.4
Covacci, V.5
Maggiano, M.6
Ranelletti, F.O.7
Wolf, F.I.8
Calviello, G.9
-
11
-
-
0029126754
-
Redox signalling by transcription factors NF-κB and AP-1 in the immune system
-
Schulze-Osthoff, K., Los, M. & Baeuerle P. A. (1995) Redox signalling by transcription factors NF-κB and AP-1 in the immune system. Biochem. Pharmacol. 50: 735-741.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 735-741
-
-
Schulze-Osthoff, K.1
Los, M.2
Baeuerle, P.A.3
-
12
-
-
0029984062
-
Antioxidant and redox regulation of gene transcription
-
Sen, C. H. & Packer, L. (1996) Antioxidant and redox regulation of gene transcription. FASEB J. 10: 709-720.
-
(1996)
FASEB J.
, vol.10
, pp. 709-720
-
-
Sen, C.H.1
Packer, L.2
-
13
-
-
0031044832
-
Redox regulation of NF-kappa B activation
-
Flohé, L., Brigelius-Flohé, R., Saliou, C., Traber, M. G. & Packer, L. (1997) Redox regulation of NF-kappa B activation. Free Radic. Biol. Med. 22: 1115-1126.
-
(1997)
Free Radic. Biol. Med.
, vol.22
, pp. 1115-1126
-
-
Flohé, L.1
Brigelius-Flohé, R.2
Saliou, C.3
Traber, M.G.4
Packer, L.5
-
14
-
-
0031595201
-
Redox signals and NF-κB activation in T cells
-
Ginn-Pease, M. E. & Whisler, R. L. (1998) Redox signals and NF-κB activation in T cells. Free Radic. Biol. Med. 25: 346-361.
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 346-361
-
-
Ginn-Pease, M.E.1
Whisler, R.L.2
-
15
-
-
0033216629
-
NF-κB as a primary regulator of the stress response
-
Mercurio, F. & Manning, A. M. (1999) NF-κB as a primary regulator of the stress response. Oncogene 18: 6163-6171.
-
(1999)
Oncogene
, vol.18
, pp. 6163-6171
-
-
Mercurio, F.1
Manning, A.M.2
-
16
-
-
0033990345
-
Oxidative stress and nuclear factor-κB activation
-
Bowie, A. & O'Neill, L. A. J. (2000) Oxidative stress and nuclear factor-κB activation. Biochem. Pharmacol. 59: 13-23.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 13-23
-
-
Bowie, A.1
O'Neill, L.A.J.2
-
17
-
-
0028174061
-
Function and activation of NF-κB in the immune system
-
Baeuerle, P. A. & Henkel, T. (1994) Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12: 141-179.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
18
-
-
0027979264
-
Differential regulation of the c-myc oncogene promoter by the NF-κB Rel family of transcription factors
-
La Rosa, F. A., Pierce, J. W. & Sonenshein, G. E. (1994) Differential regulation of the c-myc oncogene promoter by the NF-κB Rel family of transcription factors. Mol. Cell. Biol. 14: 1039-1044.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1039-1044
-
-
La Rosa, F.A.1
Pierce, J.W.2
Sonenshein, G.E.3
-
19
-
-
0029670250
-
G-Protein-coupled receptors in HL-60 human leukemia cells
-
Klinder, J. F., Wenzel-Seifert, K. & Seifert, R. (1996) G-Protein-coupled receptors in HL-60 human leukemia cells. Gen. Pharmacol. 27: 33-54.
-
(1996)
Gen. Pharmacol.
, vol.27
, pp. 33-54
-
-
Klinder, J.F.1
Wenzel-Seifert, K.2
Seifert, R.3
-
20
-
-
0030179151
-
Monocytes oxygenation activities are significantly influenced by non-enzymatic glycosylation of collagen
-
Scatena, R., Nocca, G., De Sole, P. & Giardina, B. (1996) Monocytes oxygenation activities are significantly influenced by non-enzymatic glycosylation of collagen. J. Biolumin. Chemilumin. 11: 207-212.
-
(1996)
J. Biolumin. Chemilumin.
, vol.11
, pp. 207-212
-
-
Scatena, R.1
Nocca, G.2
De Sole, P.3
Giardina, B.4
-
21
-
-
0025753537
-
Diverse carotenoids protect against chemically induced neoplastic transformation
-
Bertram, J. S., Pung, A., Churley, M., Kappock, IV, T. J., Wilkins, L. R. & Cooney, R. V. (1991) Diverse carotenoids protect against chemically induced neoplastic transformation. Carcinogenesis 12: 671-678.
-
(1991)
Carcinogenesis
, vol.12
, pp. 671-678
-
-
Bertram, J.S.1
Pung, A.2
Churley, M.3
Kappock T.J. IV4
Wilkins, L.R.5
Cooney, R.V.6
-
22
-
-
0027717968
-
Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
-
Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Örd, T. & Bredesen, D. E. (1993) Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science (Washington, DC) 262: 1274-1277.
-
(1993)
Science (Washington, DC)
, vol.262
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
Hahn, H.4
Gralla, E.B.5
Valentine, J.S.6
Örd, T.7
Bredesen, D.E.8
-
23
-
-
0024322509
-
Glutathione measurement by high-performance liquid chromatography separation and fluorimetric detection of the glutathione-orthophtaldehyde adduct
-
Neuschwander-Tetri, B. A. & Roll, F. J. (1989) Glutathione measurement by high-performance liquid chromatography separation and fluorimetric detection of the glutathione-orthophtaldehyde adduct. Anal. Biochem. 179: 236-241.
-
(1989)
Anal. Biochem.
, vol.179
, pp. 236-241
-
-
Neuschwander-Tetri, B.A.1
Roll, F.J.2
-
24
-
-
0033966074
-
β-carotene antagonizes the effects of elcosapentaenoic acid on cell growth and lipid peroxidation in WiDr adenocarcinoma cells
-
Palozza, P., Calviello, G., Maggiano, N., Lanza, P., Ranelletti, F. O. & Bartoli, G. M. (2000) β-Carotene antagonizes the effects of elcosapentaenoic acid on cell growth and lipid peroxidation in WiDr adenocarcinoma cells. Free Radic. Biol. Med. 28: 228-234.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 228-234
-
-
Palozza, P.1
Calviello, G.2
Maggiano, N.3
Lanza, P.4
Ranelletti, F.O.5
Bartoli, G.M.6
-
25
-
-
0021362463
-
β-carotene: An unusual type of lipid antioxidant
-
Burton, G. W., Ingold, K. U. (1984) β-Carotene: an unusual type of lipid antioxidant. Science (Washington, DC) 224: 569-573.
-
(1984)
Science (Washington, DC)
, vol.224
, pp. 569-573
-
-
Burton, G.W.1
Ingold, K.U.2
-
26
-
-
0031669520
-
Prooxidant actions of carotenoids in biologic systems
-
Palozza, P. (1998) Prooxidant actions of carotenoids in biologic systems. Nutr. Rev. 56: 257-265.
-
(1998)
Nutr. Rev.
, vol.56
, pp. 257-265
-
-
Palozza, P.1
-
27
-
-
0029868539
-
The dual roles of nutrients as antioxidants and prooxidants: Their effect on tumor cell growth
-
Schwartz, J. L. (1996) The dual roles of nutrients as antioxidants and prooxidants: their effect on tumor cell growth. J. Nutr. 126: 1221S-1227S.
-
(1996)
J. Nutr.
, vol.126
-
-
Schwartz, J.L.1
-
28
-
-
0034775553
-
Antioxidant and prooxidant properties of carotenoids
-
Young, A. J. & Lowe, G. M. (2001) Antioxidant and prooxidant properties of carotenoids. Arch. Biochem. Biophys. 385: 20-27.
-
(2001)
Arch. Biochem. Biophys.
, vol.385
, pp. 20-27
-
-
Young, A.J.1
Lowe, G.M.2
-
29
-
-
0031409891
-
Ascorbic acid and β-carotene as modulators of oxidative damage
-
Cozzi, R., Ricordy, R., Aglitti, T., Gatta, V., Perticone, P., De Salvia, R. (1997) Ascorbic acid and β-carotene as modulators of oxidative damage. Carcinogenesis 18: 223-228.
-
(1997)
Carcinogenesis
, vol.18
, pp. 223-228
-
-
Cozzi, R.1
Ricordy, R.2
Aglitti, T.3
Gatta, V.4
Perticone, P.5
De Salvia, R.6
-
30
-
-
0033950741
-
Effects of β-carotene on enzyme activity, intracellular reactive oxygen and membrane integrity with post confluent Caco-2 intestinal cells
-
Bestwick, C. S., Milne, L. (2000) Effects of β-carotene on enzyme activity, intracellular reactive oxygen and membrane integrity with post confluent Caco-2 intestinal cells. Biochim. Biophys. Acta 1474: 47-55.
-
(2000)
Biochim. Biophys. Acta
, vol.1474
, pp. 47-55
-
-
Bestwick, C.S.1
Milne, L.2
-
31
-
-
0025896688
-
Determinants of increase in plasma concentrations of β-carotene after chronic oral supplementation
-
Nierenberg, D. W., Stukel, T. A., Baron, J. A., Dain, B. S., Greenberg, E. R. (1991) Determinants of increase in plasma concentrations of β-carotene after chronic oral supplementation. Am. J. Clin. Nutr. 53: 1443-1449.
-
(1991)
Am. J. Clin. Nutr.
, vol.53
, pp. 1443-1449
-
-
Nierenberg, D.W.1
Stukel, T.A.2
Baron, J.A.3
Dain, B.S.4
Greenberg, E.R.5
-
32
-
-
0027400017
-
Beta-carotene accumulation in serum and skin
-
Prince, M. R., Frisoli, J. K. (1993) Beta-carotene accumulation in serum and skin. Am. J. Clin. Nutr. 57: 175-181.
-
(1993)
Am. J. Clin. Nutr.
, vol.57
, pp. 175-181
-
-
Prince, M.R.1
Frisoli, J.K.2
-
33
-
-
0036199442
-
Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by β-carotene through down-regulation of cyclin A and Bcl-2 family proteins
-
Palozza, P., Serini, S., Maggiano, M., Angelini, M., Boninsegna, A., Di Nicuolo, F., Ranelletti, F. O. & Calviello, G. (2002) Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by β-carotene through down-regulation of cyclin A and Bcl-2 family proteins. Carcinogenesis 23: 11-18.
-
(2002)
Carcinogenesis
, vol.23
, pp. 11-18
-
-
Palozza, P.1
Serini, S.2
Maggiano, M.3
Angelini, M.4
Boninsegna, A.5
Di Nicuolo, F.6
Ranelletti, F.O.7
Calviello, G.8
-
34
-
-
0025360652
-
Modulation of catalase activities in murine epidermal cells as a function of differentiation and exposure to 12-O-tetradecanoylphorbol-13-acetate
-
Reiners, J. J., Jr., Thai, G., Pavone, A., Rupp, T. & Kodari, E. (1990) Modulation of catalase activities in murine epidermal cells as a function of differentiation and exposure to 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis 11: 957-953.
-
(1990)
Carcinogenesis
, vol.11
, pp. 957-953
-
-
Reiners J.J., Jr.1
Thai, G.2
Pavone, A.3
Rupp, T.4
Kodari, E.5
-
35
-
-
0027997769
-
Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation
-
Shen, Q., Chada, S., Whitney, C. & Newburger, P. (1994) Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation. Blood 84: 3902-3908.
-
(1994)
Blood
, vol.84
, pp. 3902-3908
-
-
Shen, Q.1
Chada, S.2
Whitney, C.3
Newburger, P.4
-
36
-
-
0026350895
-
Increase of Cu, Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein
-
Steinkuhler, C., Sapora, O., Carri, M. T., Nagel, W., Marcocci, L., Circolo, M. R., Weser, U. & Rotilio, G. (1991) Increase of Cu, Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein. J. Biol. Chem. 266: 24580-24587.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 24580-24587
-
-
Steinkuhler, C.1
Sapora, O.2
Carri, M.T.3
Nagel, W.4
Marcocci, L.5
Circolo, M.R.6
Weser, U.7
Rotilio, G.8
-
37
-
-
0025915048
-
Characterization of products formed during the autooxidation of β-carotene
-
Handelman, G. J., van Kuijk, F.J.G.M., Chatteriee, A. & Krinsky, N. I. (1991) Characterization of products formed during the autooxidation of β-carotene. Free Radic. Biol. Med. 10: 427-433.
-
(1991)
Free Radic. Biol. Med.
, vol.10
, pp. 427-433
-
-
Handelman, G.J.1
Van Kuijk, F.J.G.M.2
Chatteriee, A.3
Krinsky, N.I.4
-
38
-
-
0025891156
-
Peroxyl radical oxidation of β-carotene: Formation of β-carotene epoxides
-
Kennedy, T. A. & Liebler, D. C. (1991) Peroxyl radical oxidation of β-carotene: formation of β-carotene epoxides. Chem. Res. Toxicol. 4: 290-295.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 290-295
-
-
Kennedy, T.A.1
Liebler, D.C.2
-
39
-
-
84986469609
-
Inhibitory effects of tocopherols and β-carotene on singlet oxygen-initiated photooxidation of methyl linoleate and soybean oil
-
Terao, J., Yamauchi, R., Murakami, H. & Matsushita, S. (1980) Inhibitory effects of tocopherols and β-carotene on singlet oxygen-initiated photooxidation of methyl linoleate and soybean oil. J. Food Process Preserv. 4: 79-93.
-
(1980)
J. Food Process Preserv.
, vol.4
, pp. 79-93
-
-
Terao, J.1
Yamauchi, R.2
Murakami, H.3
Matsushita, S.4
-
40
-
-
0000795228
-
Action of β-carotene on purified rapeseed oil during light storage
-
Haila, K. & Heinonen, M. (1994) Action of β-carotene on purified rapeseed oil during light storage. Lebensm.-Wiss. Technol. 27: 573-577.
-
(1994)
Lebensm.-Wiss. Technol.
, vol.27
, pp. 573-577
-
-
Haila, K.1
Heinonen, M.2
-
41
-
-
0026688491
-
β-carotene and α-tocopherol are synergistic antioxidants
-
Palozza, P. & Krinsky, N. I. (1992) β-Carotene and α-tocopherol are synergistic antioxidants. Arch. Biochem. Biophys. 297: 184-187.
-
(1992)
Arch. Biochem. Biophys.
, vol.297
, pp. 184-187
-
-
Palozza, P.1
Krinsky, N.I.2
-
44
-
-
0028887591
-
Flow cytometric analysis of the granulocyte respiratory burst: A comparison study of the fluorescent probes
-
Vowells, S. J., Sekhsaria, S., Malech, H. L., Shalit, M. & Fleisher, T. A. (1995) Flow cytometric analysis of the granulocyte respiratory burst: a comparison study of the fluorescent probes. J. Immunol. Methods 178: 89-97.
-
(1995)
J. Immunol. Methods
, vol.178
, pp. 89-97
-
-
Vowells, S.J.1
Sekhsaria, S.2
Malech, H.L.3
Shalit, M.4
Fleisher, T.A.5
-
45
-
-
0032783532
-
Dihydroflurescein diacetate is superior for detecting intracellular oxidants: Comparison with 2′, 7′-dichlorodihydrofluorescein diacetate, 5 (and 6)-carboxy-2′, 7′-dichlorodihydrofluorescein diacetate, and dihydrhodamine 123
-
Hempel, S. L., Buettner, G. R., O'Malley, Y. Q., Wessels, D. A. & Flaherty, D. M. (1999) Dihydroflurescein diacetate is superior for detecting intracellular oxidants: comparison with 2′, 7′-dichlorodihydrofluorescein diacetate, 5 (and 6)-carboxy-2′, 7′-dichlorodihydrofluorescein diacetate, and dihydrhodamine 123. Free Radic. Biol. Med. 27: 146-159.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 146-159
-
-
Hempel, S.L.1
Buettner, G.R.2
O'Malley, Y.Q.3
Wessels, D.A.4
Flaherty, D.M.5
-
46
-
-
0033024459
-
The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-kappa B
-
Shi, X., Dong, Z., Huang, C., Ma, W., Liu, K., Ye, J., Chen, F., Leonard, S. S., Ding, M., Castranova, V. & Vallyathan, V. (1999) The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-kappa B. Mol. Cell. Biochem. 194: 63-70.
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(1999)
Mol. Cell. Biochem.
, vol.194
, pp. 63-70
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Shi, X.1
Dong, Z.2
Huang, C.3
Ma, W.4
Liu, K.5
Ye, J.6
Chen, F.7
Leonard, S.S.8
Ding, M.9
Castranova, V.10
Vallyathan, V.11
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