A naturally occurring carotenoid, lutein, reduces PDGF and H 2O2signaling and compromised migration in cultured vascular smooth muscle cells

Journal of Biomedical Science

Volumn 19, Issue 1, 2012, Pages

  Lo, Huey Ming ^a,b   Tsai, Yih Jeng ^a   Du, Wen Yuan ^b   Tsou, Chih Jen ^b   Wu, Wen Bin ^b  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

binding; carotenoid; lutein; migration; oxidative stress; signaling

Indexed keywords

HYDROGEN PEROXIDE; LYCOPENE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C GAMMA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; XANTHOPHYLL; ZEAXANTHIN; ANTIOXIDANT; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CELL MOVEMENT; CELLS, CULTURED; FLOW CYTOMETRY; HYDROGEN PEROXIDE; LUTEIN; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; XANTHOPHYLLS;

EID: 84856596398     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-19-18     Document Type: Article

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