-
1
-
-
8844246477
-
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
-
Grundy SM, Cleeman JI, Merz CN, Brewer HBJ, Clark LT, et al. 2004. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Arterioscler. Thromb. Vasc. Biol. 24:e149-61
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
-
-
Grundy, S.M.1
Cleeman, J.I.2
Merz, C.N.3
Brewer, H.B.J.4
Clark, L.T.5
-
2
-
-
0023544459
-
Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population
-
Kesäniemi YA, Miettinen TA. 1997. Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population. Eur. J. Clin, Invest, 17:391-95
-
(1997)
Eur. J. Clin, Invest
, vol.17
, pp. 391-395
-
-
Kesäniemi, Y.A.1
Miettinen, T.A.2
-
3
-
-
0030725867
-
Long-term cholesterol-lowering effects of 4 fat-restricted diets in hypercholesterolemic and combined hyperlipidemic men. The Dietary Alternatives Study
-
Knopp RH, Walden CE, Retzlaff BM, McCann BS, Dowdy AA, et al. 1997. Long-term cholesterol-lowering effects of 4 fat-restricted diets in hypercholesterolemic and combined hyperlipidemic men. The Dietary Alternatives Study. J. Amer. Med. Assoc. 278:1509-15
-
(1997)
J. Amer. Med. Assoc
, vol.278
, pp. 1509-1515
-
-
Knopp, R.H.1
Walden, C.E.2
Retzlaff, B.M.3
McCann, B.S.4
Dowdy, A.A.5
-
4
-
-
0032955055
-
Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report ofthe Lyon Diet Heart Study
-
De Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. 1999. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report ofthe Lyon Diet Heart Study. Circulation 99:779-85
-
(1999)
Circulation
, vol.99
, pp. 779-785
-
-
De Lorgeril, M.1
Salen, P.2
Martin, J.L.3
Monjaud, I.4
Delaye, J.5
Mamelle, N.6
-
5
-
-
0033552130
-
Colesevelam hydrochloride (cholestagel): A new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects
-
Davidson MH, Dillon MA, Gordon B, Jones P, Samuels J, et al. 1999. Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects. Arch. Intern. Med. 159:1893-1900
-
(1999)
Arch. Intern. Med
, vol.159
, pp. 1893-1900
-
-
Davidson, M.H.1
Dillon, M.A.2
Gordon, B.3
Jones, P.4
Samuels, J.5
-
6
-
-
0034774221
-
Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: A 24-week randomized controlled trial
-
Insull WJ Toth P, Mullican W, Hunninghake D, Burke S, et al. 2001. Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: a 24-week randomized controlled trial. Mayo Clin. Proc. 76:971-82
-
(2001)
Mayo Clin. Proc
, vol.76
, pp. 971-982
-
-
Insull, W.J.1
Toth, P.2
Mullican, W.3
Hunninghake, D.4
Burke, S.5
-
7
-
-
0034973775
-
Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet
-
Maki KC, Davidson MH, Umporowicz DM, Schaefer EJ, Dicklin MR, et al. 2001. Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet. Am. J. Clin. Nutr. 74:33-43
-
(2001)
Am. J. Clin. Nutr
, vol.74
, pp. 33-43
-
-
Maki, K.C.1
Davidson, M.H.2
Umporowicz, D.M.3
Schaefer, E.J.4
Dicklin, M.R.5
-
8
-
-
0028822216
-
Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population
-
Miettinen TA, Puska P, Gylling H, Vanhanen H, Vartiainen E. 1995. Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population. N. Engl. J. Med. 333:1308-12
-
(1995)
N. Engl. J. Med
, vol.333
, pp. 1308-1312
-
-
Miettinen, T.A.1
Puska, P.2
Gylling, H.3
Vanhanen, H.4
Vartiainen, E.5
-
10
-
-
0035169826
-
ObelHyx Study Group. The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: A randomized, double-blind, placebo-controlled, multicentre study
-
Muls E, Kolanowski J, Scheen A, Van Gaal L. 2001. ObelHyx Study Group. The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled, multicentre study. Int. J. Obes. Relat. Metab. Disord. 25:1713-21
-
(2001)
Int. J. Obes. Relat. Metab. Disord
, vol.25
, pp. 1713-1721
-
-
Muls, E.1
Kolanowski, J.2
Scheen, A.3
Van Gaal, L.4
-
11
-
-
0034965751
-
Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia
-
Insull WJ Koren M, Davignon J, Sprecher D, Schrott H, et al. 2001. Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia. Atherosclerosis 157:137-44
-
(2001)
Atherosclerosis
, vol.157
, pp. 137-144
-
-
Insull, W.J.1
Koren, M.2
Davignon, J.3
Sprecher, D.4
Schrott, H.5
-
12
-
-
0037630623
-
The safety and immunogenicity of a CETP vaccine in healthy adults
-
Davidson MH, Maki K, Umporowicz D, Wheeler A, Rittershaus C, Ryan U. 2003. The safety and immunogenicity of a CETP vaccine in healthy adults. Atherosclerosis 169:113-20
-
(2003)
Atherosclerosis
, vol.169
, pp. 113-120
-
-
Davidson, M.H.1
Maki, K.2
Umporowicz, D.3
Wheeler, A.4
Rittershaus, C.5
Ryan, U.6
-
13
-
-
0032510318
-
Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl] -(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235): A designed, potent, orally active inhibitor of cholesterol absorption
-
Rosenblum SB, Huynh T, Afonso A, Davis HRJ, Yumibe N, et al. 1998. Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl] -(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption. J. Med. Chem. 41:973-80
-
(1998)
J. Med. Chem
, vol.41
, pp. 973-980
-
-
Rosenblum, S.B.1
Huynh, T.2
Afonso, A.3
Davis, H.R.J.4
Yumibe, N.5
-
14
-
-
0028341682
-
2-Azetidinones as inhibitors of cholesterol absorption
-
Burnett DA, Caplen MA, Davis HRJ, Burrier RE, Clader JW. 1994. 2-Azetidinones as inhibitors of cholesterol absorption. J. Med. Chem. 37:1733-36
-
(1994)
J. Med. Chem
, vol.37
, pp. 1733-1736
-
-
Burnett, D.A.1
Caplen, M.A.2
Davis, H.R.J.3
Burrier, R.E.4
Clader, J.W.5
-
15
-
-
0038054346
-
Ezetimbe Study Group. Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: A pooled analysis from two controlled phase III clinical studies
-
Knopp RH, Dujovne CA, Le Beaut A, Lipka LJ, Suresh R, Veltri EP. 2003. Ezetimbe Study Group. Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies. Int. J. Clin. Pract. 57:363-68
-
(2003)
Int. J. Clin. Pract
, vol.57
, pp. 363-368
-
-
Knopp, R.H.1
Dujovne, C.A.2
Le Beaut, A.3
Lipka, L.J.4
Suresh, R.5
Veltri, E.P.6
-
16
-
-
0034747715
-
Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: Results of a multicenter dose-ranging study
-
Dujovne CA, Bays H, Davidson MH, Knopp R, Hunninghake DB, et al. 2001. Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study. J. Clin. Pharmacol. 41:70-78
-
(2001)
J. Clin. Pharmacol
, vol.41
, pp. 70-78
-
-
Dujovne, C.A.1
Bays, H.2
Davidson, M.H.3
Knopp, R.4
Hunninghake, D.B.5
-
17
-
-
17944380533
-
Ezetimibe Study Group. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies
-
Bays HE, Moore PB, Drehobl MA, Rosenblatt S, Toth PD, et al. 2001. Ezetimibe Study Group. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies. Clin. Ther. 23:1209-30
-
(2001)
Clin. Ther
, vol.23
, pp. 1209-1230
-
-
Bays, H.E.1
Moore, P.B.2
Drehobl, M.A.3
Rosenblatt, S.4
Toth, P.D.5
-
18
-
-
0037111924
-
Esetimibe Study Group. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
-
Dujovne CA, Ettinger MP, McNeer JF, Lipka LJ, LeBeaut AP, et al. 2002. Esetimibe Study Group. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am, J. Cardiol. 90:1092-97
-
(2002)
Am, J. Cardiol
, vol.90
, pp. 1092-1097
-
-
Dujovne, C.A.1
Ettinger, M.P.2
McNeer, J.F.3
Lipka, L.J.4
LeBeaut, A.P.5
-
19
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
75
-
Berge KE, Tian H, Graf GA, Yu L, Grishin NV, et al. 2000. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290:1771-75
-
(1771)
Science
, vol.290
-
-
Berge, K.E.1
Tian, H.2
Graf, G.A.3
Yu, L.4
Grishin, N.V.5
-
20
-
-
0035158733
-
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
-
Lee MH, Lu K, Hazard S, Yu H, Shulenin S, et al. 2001. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat. Genet. 27:79-83
-
(2001)
Nat. Genet
, vol.27
, pp. 79-83
-
-
Lee, M.H.1
Lu, K.2
Hazard, S.3
Yu, H.4
Shulenin, S.5
-
21
-
-
0016366624
-
β-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters
-
Bhattacharyya AK, Connor WE. 1974. β-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters. J. Clin. Invest. 53:1033-43
-
(1974)
J. Clin. Invest
, vol.53
, pp. 1033-1043
-
-
Bhattacharyya, A.K.1
Connor, W.E.2
-
22
-
-
10744221008
-
Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption
-
Altmann SW, Davis HRJ, Zhu LJ, Yao X, Hoos LM, et al. 2004. Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption. Science 303:1201-4
-
(2004)
Science
, vol.303
, pp. 1201-1204
-
-
Altmann, S.W.1
Davis, H.R.J.2
Zhu, L.J.3
Yao, X.4
Hoos, L.M.5
-
23
-
-
4043124013
-
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
-
Davis HR, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, et al. 2004. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J. Biol. Chem. 279:33586-92
-
(2004)
J. Biol. Chem
, vol.279
, pp. 33586-33592
-
-
Davis, H.R.1
Zhu, L.J.2
Hoos, L.M.3
Tetzloff, G.4
Maguire, M.5
-
24
-
-
0037040172
-
Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine. A process mediated via ceramide hydrolysis
-
Kirby RJ, Zheng S, Tso P, Howles PN, Hui DY. 2002. Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine. A process mediated via ceramide hydrolysis. J. Biol. Chem. 277:4104-9
-
(2002)
J. Biol. Chem
, vol.277
, pp. 4104-4109
-
-
Kirby, R.J.1
Zheng, S.2
Tso, P.3
Howles, P.N.4
Hui, D.Y.5
-
25
-
-
0033616639
-
Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice
-
Weng W, Li L, Van Bennekum AM, Potter SH, Harrison EH, et al. 1999. Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice. Biochemistry 38:4143-49
-
(1999)
Biochemistry
, vol.38
, pp. 4143-4149
-
-
Weng, W.1
Li, L.2
Van Bennekum, A.M.3
Potter, S.H.4
Harrison, E.H.5
-
26
-
-
0242322024
-
Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice
-
Huggins KW, Camarota LM, Howles PN, Hui DY. 2003. Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice. J. Biol. Chem. 278:42899-905
-
(2003)
J. Biol. Chem
, vol.278
, pp. 42899-42905
-
-
Huggins, K.W.1
Camarota, L.M.2
Howles, P.N.3
Hui, D.Y.4
-
27
-
-
0041965752
-
Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: Studies in the gallstone-susceptible mouse
-
Wang DQH, Tazuma S, Cohen DE, Carey MC. 2003. Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse. Am. J. Physiol. 285:G494-502
-
(2003)
Am. J. Physiol
, vol.285
-
-
Wang, D.Q.H.1
Tazuma, S.2
Cohen, D.E.3
Carey, M.C.4
-
28
-
-
0032953973
-
Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis
-
Wang DQH, Lammert F, Cohen DE, Paigen B, Carey MC. 1999. Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis. Am. J. Physiol. 276:G751-60
-
(1999)
Am. J. Physiol
, vol.276
-
-
Wang, D.Q.H.1
Lammert, F.2
Cohen, D.E.3
Paigen, B.4
Carey, M.C.5
-
30
-
-
0034520194
-
Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
-
Lee RG, Willingham MC, Davis MA, Skinner KA, Rudel LL. 2000. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J. Lipid Res. 41:1991-2001
-
(2000)
J. Lipid Res
, vol.41
, pp. 1991-2001
-
-
Lee, R.G.1
Willingham, M.C.2
Davis, M.A.3
Skinner, K.A.4
Rudel, L.L.5
-
31
-
-
0031882256
-
Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: Interaction with saturated and unsaturated dietary fatty acids
-
van Greevenbroek MM, Robertus-Teunissen MG, Erkelens DW, de Bruin TW. 1998. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids. J. Lipid Res. 39:173-85
-
(1998)
J. Lipid Res
, vol.39
, pp. 173-185
-
-
van Greevenbroek, M.M.1
Robertus-Teunissen, M.G.2
Erkelens, D.W.3
de Bruin, T.W.4
-
32
-
-
0021367211
-
Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function
-
Bennett Clark S, Tercyak AM. 1984. Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function. J. Lipid Res. 25:148-59
-
(1984)
J. Lipid Res
, vol.25
, pp. 148-159
-
-
Bennett Clark, S.1
Tercyak, A.M.2
-
33
-
-
0021043541
-
Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit
-
Heider JG, Pickens CE, Kelly LA. 1983. Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit. J. Lipid Res. 24:1127-34
-
(1983)
J. Lipid Res
, vol.24
, pp. 1127-1134
-
-
Heider, J.G.1
Pickens, C.E.2
Kelly, L.A.3
-
34
-
-
0034529633
-
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice
-
Buhman KK, Accad M, Novak S, Choi RS, Wong JS, et al. 2000. Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice. Nat. Med. 6:1341-47
-
(2000)
Nat. Med
, vol.6
, pp. 1341-1347
-
-
Buhman, K.K.1
Accad, M.2
Novak, S.3
Choi, R.S.4
Wong, J.S.5
-
35
-
-
0027536829
-
Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits
-
Nielsen LB, Stender S, Kjeldsen K. 1993. Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits. Pharmacol. Toxicol. 72:148-51
-
(1993)
Pharmacol. Toxicol
, vol.72
, pp. 148-151
-
-
Nielsen, L.B.1
Stender, S.2
Kjeldsen, K.3
-
36
-
-
0028840812
-
Crilvastatin, a new 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, inhibits cholesterol absorption in genetically hypercholesterolemic rats
-
Hajri T, Ferezou J, Laruelle C, Lutton C. 1995. Crilvastatin, a new 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, inhibits cholesterol absorption in genetically hypercholesterolemic rats. Eur. J. Pharmacol. 286:131-36
-
(1995)
Eur. J. Pharmacol
, vol.286
, pp. 131-136
-
-
Hajri, T.1
Ferezou, J.2
Laruelle, C.3
Lutton, C.4
-
37
-
-
0026623506
-
Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man
-
Vanhanen H, Kesaniemi YA, Miettinen TA. 1992. Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man. Metabolism 41:588-95
-
(1992)
Metabolism
, vol.41
, pp. 588-595
-
-
Vanhanen, H.1
Kesaniemi, Y.A.2
Miettinen, T.A.3
-
38
-
-
0028821841
-
A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver, but not in the intestine
-
Young SG, Cham CM, Pitas RE, Burri BJ, Connolly A, et al. 1995. A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine. J. Clin. Invest. 96:2932-46
-
(1995)
J. Clin. Invest
, vol.96
, pp. 2932-2946
-
-
Young, S.G.1
Cham, C.M.2
Pitas, R.E.3
Burri, B.J.4
Connolly, A.5
-
39
-
-
23244453526
-
Reduced susceptibility to cholesterol gallstone formation in mice that do not produce apolipoprotein B48 in the intestine
-
Wang HH, Wang DQH. 2005. Reduced susceptibility to cholesterol gallstone formation in mice that do not produce apolipoprotein B48 in the intestine. Hepatology 42:894-904
-
(2005)
Hepatology
, vol.42
, pp. 894-904
-
-
Wang, H.H.1
Wang, D.Q.H.2
-
40
-
-
12644303527
-
Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step
-
Gordon DA, Jamil H, Gregg RE, Olofsson SO, Boren J. 1996. Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step. J. Biol. Chem. 271:33047-53
-
(1996)
J. Biol. Chem
, vol.271
, pp. 33047-33053
-
-
Gordon, D.A.1
Jamil, H.2
Gregg, R.E.3
Olofsson, S.O.4
Boren, J.5
-
41
-
-
0026470990
-
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
-
Wetterau JR, Aggerbeck LP, Bouma ME, Eisenberg C, Munck A, et al. 1992. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science 258:999-1001
-
(1992)
Science
, vol.258
, pp. 999-1001
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Bouma, M.E.3
Eisenberg, C.4
Munck, A.5
-
42
-
-
0034078501
-
Genetic determinants of plasma lipid response to dietary intervention: The role ofthe APOA1/C3/A4 gene cluster and the APOE gene
-
Ordovas JM, Schaefer EJ. 2000. Genetic determinants of plasma lipid response to dietary intervention: the role ofthe APOA1/C3/A4 gene cluster and the APOE gene. Br. J. Nutr. 83:S127-36
-
(2000)
Br. J. Nutr
, vol.83
-
-
Ordovas, J.M.1
Schaefer, E.J.2
-
43
-
-
0034762627
-
Alternate pathways of bile acid synthesis in the cholesterol 7α-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding
-
Schwarz M, Russell DW, Dietschy JM, Turley SD. 2001. Alternate pathways of bile acid synthesis in the cholesterol 7α-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding. J. Lipid Res. 42:1594-603
-
(2001)
J. Lipid Res
, vol.42
, pp. 1594-1603
-
-
Schwarz, M.1
Russell, D.W.2
Dietschy, J.M.3
Turley, S.D.4
-
44
-
-
0034671509
-
Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding
-
Repa JJ, Lund EG, Horton JD, Leitersdorf E, Russell DW, et al. 2000. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding. J. Biol. Chem. 275:39685-92
-
(2000)
J. Biol. Chem
, vol.275
, pp. 39685-39692
-
-
Repa, J.J.1
Lund, E.G.2
Horton, J.D.3
Leitersdorf, E.4
Russell, D.W.5
-
45
-
-
0023030762
-
Cholesterol gallstones in alloxan-diabetic mice
-
Akiyoshi T, Uchida K, Takase H, Nomura Y, Takeuchi N. 1986. Cholesterol gallstones in alloxan-diabetic mice. J. Lipid Res. 27:915-24
-
(1986)
J. Lipid Res
, vol.27
, pp. 915-924
-
-
Akiyoshi, T.1
Uchida, K.2
Takase, H.3
Nomura, Y.4
Takeuchi, N.5
-
46
-
-
0031957144
-
Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice
-
Voshol PJ, Havinga R, Wolters H, Ottenhoff R, Princen HM, et al. 1998. Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice. Gastroenterology 114:1024-34
-
(1998)
Gastroenterology
, vol.114
, pp. 1024-1034
-
-
Voshol, P.J.1
Havinga, R.2
Wolters, H.3
Ottenhoff, R.4
Princen, H.M.5
-
47
-
-
0000356477
-
Hyposecretion of biliary phospholipids significantly decreases the intestinal absorption of cholesterol in Mdr2 (-/-) and (+/-) mice
-
Abstr
-
Wang DQH, Lammert F, Cohen DE, Paigen B, Carey MC. 1998. Hyposecretion of biliary phospholipids significantly decreases the intestinal absorption of cholesterol in Mdr2 (-/-) and (+/-) mice. Gastroenterology 114:A913 (Abstr.)
-
(1998)
Gastroenterology
, vol.114
-
-
Wang, D.Q.H.1
Lammert, F.2
Cohen, D.E.3
Paigen, B.4
Carey, M.C.5
-
48
-
-
0141818009
-
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice
-
Dawson PA, Haywood J, Craddock AL, Wilson M, Tietjen M, et al. 2003. Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J. Biol. Chem. 278:33920-27
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33920-33927
-
-
Dawson, P.A.1
Haywood, J.2
Craddock, A.L.3
Wilson, M.4
Tietjen, M.5
-
49
-
-
85047693084
-
Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
-
Wang DQH, Schmitz F, Kopin AS, Carey MC. 2004. Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis. J. Clin. Invest. 114:521-28
-
(2004)
J. Clin. Invest
, vol.114
, pp. 521-528
-
-
Wang, D.Q.H.1
Schmitz, F.2
Kopin, A.S.3
Carey, M.C.4
-
50
-
-
0018140522
-
Cholesterol absorption and steroid excretion in cholesterol-fed guinea pigs
-
Traber MG, Ostwald R. 1978. Cholesterol absorption and steroid excretion in cholesterol-fed guinea pigs. J. Lipid Res. 19:448-56
-
(1978)
J. Lipid Res
, vol.19
, pp. 448-456
-
-
Traber, M.G.1
Ostwald, R.2
-
51
-
-
0020322491
-
Influence of small-bowel transit time on dietary cholesterol absorption in human beings
-
Ponz de Leon M, Iori R, Barbolini G, Pompei G, Zaniol P, Carulli N. 1982. Influence of small-bowel transit time on dietary cholesterol absorption in human beings. N. Engl. J. Med. 307:102-3
-
(1982)
N. Engl. J. Med
, vol.307
, pp. 102-103
-
-
Ponz de Leon, M.1
Iori, R.2
Barbolini, G.3
Pompei, G.4
Zaniol, P.5
Carulli, N.6
-
52
-
-
0035199905
-
Genetic factors at the enterocyte level account for variations in intestinal cholesterol absorption efficiency among inbred strains of mice
-
30
-
Wang DQH, Paigen B, Carey MC. 2001. Genetic factors at the enterocyte level account for variations in intestinal cholesterol absorption efficiency among inbred strains of mice. J. Lipid Res. 42:1820-30
-
(1820)
J. Lipid Res
, vol.42
-
-
Wang, D.Q.H.1
Paigen, B.2
Carey, M.C.3
-
53
-
-
0036846873
-
Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice
-
Wang DQH. 2002. Aging per se is an independent risk factor for cholesterol gallstone formation in gallstone susceptible mice. J. Lipid Res. 43:1950-59
-
(2002)
J. Lipid Res
, vol.43
, pp. 1950-1959
-
-
Wang, D.Q.H.1
-
54
-
-
0018646633
-
Increase in cholesterol intestinal absorption with aging in the rat
-
Hollander D, Morgan D. 1979. Increase in cholesterol intestinal absorption with aging in the rat. Exp. Gerontol. 14:201-4
-
(1979)
Exp. Gerontol
, vol.14
, pp. 201-204
-
-
Hollander, D.1
Morgan, D.2
-
55
-
-
33644859300
-
Role of intestinal sterol transporters Abcg5, Abcg8, and Npc1l1 in cholesterol absorption in mice: Gender and age effects
-
Duan P, Wang HH, Ohashi A, Wang DQH. 2006. Role of intestinal sterol transporters Abcg5, Abcg8, and Npc1l1 in cholesterol absorption in mice: gender and age effects. Am. J. Physiol. 290:G269-76
-
(2006)
Am. J. Physiol
, vol.290
-
-
Duan, P.1
Wang, H.H.2
Ohashi, A.3
Wang, D.Q.H.4
-
56
-
-
0031705365
-
Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets
-
Turley SD, Schwarz M, Spady DK, Dietschy JM. 1998. Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets. Hepatology 28:1088-94
-
(1998)
Hepatology
, vol.28
, pp. 1088-1094
-
-
Turley, S.D.1
Schwarz, M.2
Spady, D.K.3
Dietschy, J.M.4
-
57
-
-
3242694494
-
Estrogen receptor α, but not β, plays a major role in 17β-estradiol-induced murine cholesterol gallstones
-
Wang HH, Afdhal NH, Wang DQH. 2004. Estrogen receptor α, but not β, plays a major role in 17β-estradiol-induced murine cholesterol gallstones. Gastroenterology 127:239-49
-
(2004)
Gastroenterology
, vol.127
, pp. 239-249
-
-
Wang, H.H.1
Afdhal, N.H.2
Wang, D.Q.H.3
-
59
-
-
0024450180
-
Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma
-
Henriksson P, Einarsson K, Eriksson A, Kelter U, Angelin B. 1989. Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma. J. Clin. Invest. 84:811-16
-
(1989)
J. Clin. Invest
, vol.84
, pp. 811-816
-
-
Henriksson, P.1
Einarsson, K.2
Eriksson, A.3
Kelter, U.4
Angelin, B.5
-
60
-
-
0018140509
-
Age-related changes in cholesterol and bile acid metabolism in rats
-
Uchida K, Nomura Y, Kadowaki M, Takase H, Takano K, Takeuchi N. 1978. Age-related changes in cholesterol and bile acid metabolism in rats. J. Lipid Res. 19:544-52
-
(1978)
J. Lipid Res
, vol.19
, pp. 544-552
-
-
Uchida, K.1
Nomura, Y.2
Kadowaki, M.3
Takase, H.4
Takano, K.5
Takeuchi, N.6
-
61
-
-
0021811872
-
Influence of age on secretion of cholesterol and synthesis of bile acids by the liver
-
Einarsson K, Nilsell K, Leijd B, Angelin B. 1985. Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N. Engl. J. Med. 313:277-82
-
(1985)
N. Engl. J. Med
, vol.313
, pp. 277-282
-
-
Einarsson, K.1
Nilsell, K.2
Leijd, B.3
Angelin, B.4
-
62
-
-
0017842336
-
Effect of aging on biliary lipid composition and bile acid metabolism in normal Chilean women
-
Valdivieso V, Palma R, Wünkhaus R, Antezana C, Severín C, Contreras A. 1978. Effect of aging on biliary lipid composition and bile acid metabolism in normal Chilean women. Gastroenterology 74:871-74
-
(1978)
Gastroenterology
, vol.74
, pp. 871-874
-
-
Valdivieso, V.1
Palma, R.2
Wünkhaus, R.3
Antezana, C.4
Severín, C.5
Contreras, A.6
-
63
-
-
0019199986
-
Cholesterol absorption and turnover in rhesus monkey as measured by two methods
-
Bhattacharyya AK, Eggen DA. 1980. Cholesterol absorption and turnover in rhesus monkey as measured by two methods. J. Lipid Res. 21:518-24
-
(1980)
J. Lipid Res
, vol.21
, pp. 518-524
-
-
Bhattacharyya, A.K.1
Eggen, D.A.2
-
64
-
-
0015471598
-
Studies on the regulation of plasma cholesterol levels in squirrel monkeys of two genotypes
-
Lofland HBJ, Clarkson TB, St. Clair RW, Lehner NDM. 1972. Studies on the regulation of plasma cholesterol levels in squirrel monkeys of two genotypes. J. Lipid Res. 13:39-47
-
(1972)
J. Lipid Res
, vol.13
, pp. 39-47
-
-
Lofland, H.B.J.1
Clarkson, T.B.2
St. Clair, R.W.3
Lehner, N.D.M.4
-
65
-
-
0032440396
-
U-shape relationship between change in dietary cholesterol absorption and plasma lipoprotein responsiveness and evidence for extreme interindividual variation in dietary cholesterol absorption in humans
-
Sehayek E, Nath C, Heinemann T, McGee M, Seidman CE, et al. 1998. U-shape relationship between change in dietary cholesterol absorption and plasma lipoprotein responsiveness and evidence for extreme interindividual variation in dietary cholesterol absorption in humans. J. Lipid Res. 39:2415-22
-
(1998)
J. Lipid Res
, vol.39
, pp. 2415-2422
-
-
Sehayek, E.1
Nath, C.2
Heinemann, T.3
McGee, M.4
Seidman, C.E.5
-
66
-
-
0023256652
-
Heterogeneity of cholesterol homeostasis in man. Response to changes in dietary fat quality and cholesterol quantity
-
McNamara DJ, Kolb R, Parker TS, Batwin H, Samuel P, et al. 1987. Heterogeneity of cholesterol homeostasis in man. Response to changes in dietary fat quality and cholesterol quantity. J. Clin. Invest. 79:1729-39
-
(1987)
J. Clin. Invest
, vol.79
, pp. 1729-1739
-
-
McNamara, D.J.1
Kolb, R.2
Parker, T.S.3
Batwin, H.4
Samuel, P.5
-
67
-
-
0032913411
-
Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry
-
Bosner MS, Lange LG, Stenson WF, Ostlund REJ. 1999. Percent cholesterol absorption in normal women and men quantified with dual stable isotopic tracers and negative ion mass spectrometry. J. Lipid Res. 40:302-8
-
(1999)
J. Lipid Res
, vol.40
, pp. 302-308
-
-
Bosner, M.S.1
Lange, L.G.2
Stenson, W.F.3
Ostlund, R.E.J.4
-
68
-
-
0025156823
-
Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population
-
Miettinen TA, Tilvis RS, Kesaniemi YA. 1990. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am. J. Epidemiol. 131:20-31
-
(1990)
Am. J. Epidemiol
, vol.131
, pp. 20-31
-
-
Miettinen, T.A.1
Tilvis, R.S.2
Kesaniemi, Y.A.3
-
69
-
-
0029134079
-
Hyperand hyporesponsiveness to dietary fat and cholesterol among inbred mice: Searching for level and variability genes
-
Kirk EA, Moe GL, Caldwell MT, Lernmark JA, Wilson DL, LeBoeuf RC. 1995. Hyperand hyporesponsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes. J. Lipid Res. 36:1522-32
-
(1995)
J. Lipid Res
, vol.36
, pp. 1522-1532
-
-
Kirk, E.A.1
Moe, G.L.2
Caldwell, M.T.3
Lernmark, J.A.4
Wilson, D.L.5
LeBoeuf, R.C.6
-
70
-
-
0030829268
-
Genetic variation in cholesterol absorption efficiency among inbred strains of mice
-
Carter CP, Howles PN, Hui DY. 1997. Genetic variation in cholesterol absorption efficiency among inbred strains of mice. J. Nutr. 127:1344-48
-
(1997)
J. Nutr
, vol.127
, pp. 1344-1348
-
-
Carter, C.P.1
Howles, P.N.2
Hui, D.Y.3
-
71
-
-
0032973755
-
Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: Effect on cholesterol responsiveness
-
Jolley CD, Dietschy JM, Turley SD. 1999. Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: effect on cholesterol responsiveness. Am. J. Physiol. 276:G1117-24
-
(1999)
Am. J. Physiol
, vol.276
-
-
Jolley, C.D.1
Dietschy, J.M.2
Turley, S.D.3
-
72
-
-
0035200286
-
Genetic analysis of intestinal cholesterol absorption in inbred mice
-
2001
-
Schwarz M, Davis DL, Vick BR, Russell DW. 2001. Genetic analysis of intestinal cholesterol absorption in inbred mice. J. Lipid Res. 42:1801-11
-
(1911)
J. Lipid Res
, vol.42
-
-
Schwarz, M.1
Davis, D.L.2
Vick, B.R.3
Russell, D.W.4
-
74
-
-
0024347985
-
Sterol balance and cholesterol absorption in inbred strains of rabbits hypo- or hyperresponsive to dietary cholesterol
-
Beynen AC, Meijer GW, Lemmens AG, Glatz JFC, Versluis A, et al. 1989. Sterol balance and cholesterol absorption in inbred strains of rabbits hypo- or hyperresponsive to dietary cholesterol. Atherosclerosis 77:151-57
-
(1989)
Atherosclerosis
, vol.77
, pp. 151-157
-
-
Beynen, A.C.1
Meijer, G.W.2
Lemmens, A.G.3
Glatz, J.F.C.4
Versluis, A.5
-
75
-
-
0017745148
-
Strain differences in response to dietary cholesterol by JAX rabbits: Correlation with esterase patterns
-
van Zutphen LFM, Fox RR. 1977. Strain differences in response to dietary cholesterol by JAX rabbits: correlation with esterase patterns. Atherosclerosis 28:435-46
-
(1977)
Atherosclerosis
, vol.28
, pp. 435-446
-
-
van Zutphen, L.F.M.1
Fox, R.R.2
-
76
-
-
0036739547
-
Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption
-
Gylling EI, Miettinen TA. 2002. Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption. J. Lipid Res. 43:1472-76
-
(2002)
J. Lipid Res
, vol.43
, pp. 1472-1476
-
-
Gylling, E.I.1
Miettinen, T.A.2
-
77
-
-
0041912965
-
Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: An analysis of direct versus indirect methodologies
-
Wang DQH, Carey MC. 2003. Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies. J. Lipid Res. 44:1042-59
-
(2003)
J. Lipid Res
, vol.44
, pp. 1042-1059
-
-
Wang, D.Q.H.1
Carey, M.C.2
-
78
-
-
0018841909
-
Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: A case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis
-
Miettinen TA. 1980. Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. Eur. J. Clin. Invest. 10:27-35
-
(1980)
Eur. J. Clin. Invest
, vol.10
, pp. 27-35
-
-
Miettinen, T.A.1
-
79
-
-
0024451905
-
Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis
-
Salen G, Shore V, Tint GS, Forte T, Shefer S, et al. 1989. Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis. J. Lipid Res. 30:1319-30
-
(1989)
J. Lipid Res
, vol.30
, pp. 1319-1330
-
-
Salen, G.1
Shore, V.2
Tint, G.S.3
Forte, T.4
Shefer, S.5
-
80
-
-
0026766590
-
Increased sitosterol absorption is offset by rapid elimination to prevent accumulation in heterozygotes with sitosterolemia
-
Salen G, Tint GS, Shefer S, Shore V, Nguyen L. 1992. Increased sitosterol absorption is offset by rapid elimination to prevent accumulation in heterozygotes with sitosterolemia. Arterioscler. Thromb. 12:563-68
-
(1992)
Arterioscler. Thromb
, vol.12
, pp. 563-568
-
-
Salen, G.1
Tint, G.S.2
Shefer, S.3
Shore, V.4
Nguyen, L.5
-
81
-
-
0034657215
-
Plant sterols: Biosynthesis, biological function and their importance to human nutrition
-
Piironen V, Lindsay DG, Miettinen TA, Toivo J, Lampi AM. 2000. Plant sterols: biosynthesis, biological function and their importance to human nutrition. J. Sci. Food Agric. 80:939-66
-
(2000)
J. Sci. Food Agric
, vol.80
, pp. 939-966
-
-
Piironen, V.1
Lindsay, D.G.2
Miettinen, T.A.3
Toivo, J.4
Lampi, A.M.5
-
82
-
-
0035987032
-
Phytosterols, phytostanols, and their conjugates in foods: Structural diversity, quantitative analysis, and health-promoting uses
-
Moreau RA, Whitaker BD, Hicks KB. 2002. Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses. Prog. Lipid Res. 41:457-500
-
(2002)
Prog. Lipid Res
, vol.41
, pp. 457-500
-
-
Moreau, R.A.1
Whitaker, B.D.2
Hicks, K.B.3
-
83
-
-
0346731237
-
The discovery of ezetimibe: A view from outside the receptor
-
Clader JW. 2004. The discovery of ezetimibe: a view from outside the receptor. J. Med. Chem, 47:1-9
-
(2004)
J. Med. Chem
, vol.47
, pp. 1-9
-
-
Clader, J.W.1
-
84
-
-
0025259298
-
Uptake of cholesterol by small intestinal brush border membrane is protein-mediated
-
Thurnhofer H, Hauser H. 1990. Uptake of cholesterol by small intestinal brush border membrane is protein-mediated. Biochemistry 29:2142-48
-
(1990)
Biochemistry
, vol.29
, pp. 2142-2148
-
-
Thurnhofer, H.1
Hauser, H.2
-
85
-
-
0029588201
-
Cholesteryl ester absorption by small intestinal brush border membrane is protein-mediated
-
Compassi S, Werder M, Boffelli D, Weber FE, Hauser H, Schulthess G. 1995. Cholesteryl ester absorption by small intestinal brush border membrane is protein-mediated. Biochemistry 34:16473-82
-
(1995)
Biochemistry
, vol.34
, pp. 16473-16482
-
-
Compassi, S.1
Werder, M.2
Boffelli, D.3
Weber, F.E.4
Hauser, H.5
Schulthess, G.6
-
86
-
-
0032167658
-
Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21
-
Patel SB, Salen G, Hidaka H, Kwiterovich PO, Stalenhoef AF, et al. 1998. Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. J. Clin. Invest, 102:1041-44
-
(1998)
J. Clin. Invest
, vol.102
, pp. 1041-1044
-
-
Patel, S.B.1
Salen, G.2
Hidaka, H.3
Kwiterovich, P.O.4
Stalenhoef, A.F.5
-
87
-
-
0036731990
-
Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface
-
Graf GA, Li WP, Gerard RD, Gelissen I, White A, et al. 2002. Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J. Clin. Invest. 110:659-69
-
(2002)
J. Clin. Invest
, vol.110
, pp. 659-669
-
-
Graf, G.A.1
Li, W.P.2
Gerard, R.D.3
Gelissen, I.4
White, A.5
-
88
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
Yu L, Hammer RE, Li-Hawkins J, von Bergmann K, Lütjohann D, et al. 2002. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc. Natl. Acad. Sci. USA 99:16237-42
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16237-16242
-
-
Yu, L.1
Hammer, R.E.2
Li-Hawkins, J.3
von Bergmann, K.4
Lütjohann, D.5
-
89
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, et al. 2002. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest. 110:671-80
-
(2002)
J. Clin. Invest
, vol.110
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
Berge, K.E.4
Horton, J.D.5
-
90
-
-
0038614979
-
Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8
-
Yu L, York J, von Bergmann K, Lütjohann D, Cohen JC, Hobbs HH. 2003. Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.J. Biol. Chem, 278:15565-70
-
(2003)
J. Biol. Chem
, vol.278
, pp. 15565-15570
-
-
Yu, L.1
York, J.2
von Bergmann, K.3
Lütjohann, D.4
Cohen, J.C.5
Hobbs, H.H.6
-
91
-
-
3042601466
-
A mouse model of sitosterolemia: Absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
-
Klett EL, Lu K, Kosters A, Vink E, Lee MH, et al. 2004. A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med. 2:5-26
-
(2004)
BMC Med
, vol.2
, pp. 5-26
-
-
Klett, E.L.1
Lu, K.2
Kosters, A.3
Vink, E.4
Lee, M.H.5
-
92
-
-
0036203457
-
Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8
-
Berge KE, von Bergmann K, Lütjohann D, Guerra R, Grundy SM, et al. 2002. Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8. J. Lipid Res. 43:486-94
-
(2002)
J. Lipid Res
, vol.43
, pp. 486-494
-
-
Berge, K.E.1
von Bergmann, K.2
Lütjohann, D.3
Guerra, R.4
Grundy, S.M.5
-
93
-
-
3042522984
-
Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice
-
Duan P, Wang HH, Wang DQH. 2004. Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice. J. Lipid Res. 45:1312-23
-
(2004)
J. Lipid Res
, vol.45
, pp. 1312-1323
-
-
Duan, P.1
Wang, H.H.2
Wang, D.Q.H.3
-
94
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β
-
Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs HH, Mangelsdorf DJ. 2002. Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β. J. Biol. Chem. 277:18793-800
-
(2002)
J. Biol. Chem
, vol.277
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.H.5
Mangelsdorf, D.J.6
-
95
-
-
0141481039
-
Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist
-
Kaneko E, Matsuda M, Yamada Y, Tachibana Y, Shimomura I, Makishima M. 2003. Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. J. Biol. Chem. 278:36091-98
-
(2003)
J. Biol. Chem
, vol.278
, pp. 36091-36098
-
-
Kaneko, E.1
Matsuda, M.2
Yamada, Y.3
Tachibana, Y.4
Shimomura, I.5
Makishima, M.6
-
96
-
-
0036845043
-
Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte
-
Repa JJ, Dietschy JM, Turley SD. 2002. Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte. J. Lipid Res. 43:1864-74
-
(2002)
J. Lipid Res
, vol.43
, pp. 1864-1874
-
-
Repa, J.J.1
Dietschy, J.M.2
Turley, S.D.3
-
97
-
-
0034776367
-
Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function
-
van Heek M, Farley C, Compton DS, Hoos L, Davis HR. 2001. Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function. Br J. Pharmacol. 134:409-17
-
(2001)
Br J. Pharmacol
, vol.134
, pp. 409-417
-
-
van Heek, M.1
Farley, C.2
Compton, D.S.3
Hoos, L.4
Davis, H.R.5
-
98
-
-
0034003105
-
Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
-
van Heek M, Farley C, Compton DS, Hoos L, Alton KB, et al. 2000. Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663. Br. J. Pharmacol. 129:1748-54
-
(2000)
Br. J. Pharmacol
, vol.129
, pp. 1748-1754
-
-
van Heek, M.1
Farley, C.2
Compton, D.S.3
Hoos, L.4
Alton, K.B.5
-
99
-
-
0030863352
-
Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
-
Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, et al. 1997. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277:228-31
-
(1997)
Science
, vol.277
, pp. 228-231
-
-
Carstea, E.D.1
Morris, J.A.2
Coleman, K.G.3
Loftus, S.K.4
Zhang, D.5
-
100
-
-
0034655917
-
Evidence for a Niemann-Pick C (NPC) gene family: Identification and characterization of NPC1L1
-
Davies JP, Levy B, Ioannou YA. 2000. Evidence for a Niemann-Pick C (NPC) gene family: identification and characterization of NPC1L1. Genomics 65:137-45
-
(2000)
Genomics
, vol.65
, pp. 137-145
-
-
Davies, J.P.1
Levy, B.2
Ioannou, Y.A.3
-
101
-
-
20444371945
-
The target of ezetimibe is Niemann-Pick C1-like 1 (NPC1L1)
-
Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, et al. 2005. The target of ezetimibe is Niemann-Pick C1-like 1 (NPC1L1). Proc. Natl. Acad. Sci. USA 102:8132-37
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8132-8137
-
-
Garcia-Calvo, M.1
Lisnock, J.2
Bull, H.G.3
Hawes, B.E.4
Burnett, D.A.5
-
102
-
-
14844359992
-
Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein
-
Iyer SPN, Yao X, Crona JH, Hoos LM, Tetzloff G, et al. 2005. Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein. Biochim. Biophys. Acta 1722:282-92
-
(2005)
Biochim. Biophys. Acta
, vol.1722
, pp. 282-292
-
-
Iyer, S.P.N.1
Yao, X.2
Crona, J.H.3
Hoos, L.M.4
Tetzloff, G.5
-
103
-
-
1542618335
-
Annexin 2-caveolin 1 complex is a target of ezetimibe and regulates intestinal cholesterol transport
-
Smart EJ, de Rose RA, Farber SA. 2004. Annexin 2-caveolin 1 complex is a target of ezetimibe and regulates intestinal cholesterol transport. Proc. Natl. Acad. Sci. USA 101:3450-55
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3450-3455
-
-
Smart, E.J.1
de Rose, R.A.2
Farber, S.A.3
-
104
-
-
0032832985
-
A fluorescent cholesterol analog traces cholesterol absorption in hamsters and is esterified in vivo and in vitro
-
Sparrow CP, Patel S, Baffic J, Chao YS, Hernandez M, et al. 1999. A fluorescent cholesterol analog traces cholesterol absorption in hamsters and is esterified in vivo and in vitro. J. Lipid Res. 40:1747-57
-
(1999)
J. Lipid Res
, vol.40
, pp. 1747-1757
-
-
Sparrow, C.P.1
Patel, S.2
Baffic, J.3
Chao, Y.S.4
Hernandez, M.5
-
105
-
-
0034731470
-
Identification of binding proteins for cholesterol absorption inhibitors as components of the intestinal cholesterol transporter
-
Kramer W, Glombik H, Petry S, Heuer H, Schafer H, et al. 2000. Identification of binding proteins for cholesterol absorption inhibitors as components of the intestinal cholesterol transporter. FEBS Lett. 487:293-97
-
(2000)
FEBS Lett
, vol.487
, pp. 293-297
-
-
Kramer, W.1
Glombik, H.2
Petry, S.3
Heuer, H.4
Schafer, H.5
-
106
-
-
0034686663
-
Intestinal absorption of cholesterol is mediated by a saturable, inhabitable transporter
-
Hernandez M, Montenegro J, Steiner M, Kim D, Sparrow C, et al. 2000. Intestinal absorption of cholesterol is mediated by a saturable, inhabitable transporter. Biochim. Biophys. Acta 1486:232-42
-
(2000)
Biochim. Biophys. Acta
, vol.1486
, pp. 232-242
-
-
Hernandez, M.1
Montenegro, J.2
Steiner, M.3
Kim, D.4
Sparrow, C.5
-
107
-
-
0034686670
-
A target for cholesterol absorption inhibitors in the enterocyte brush border membrane
-
Detmers PA, Patel S, Hernandez M, Montenegro J, Lisnock JM, et al. 2000. A target for cholesterol absorption inhibitors in the enterocyte brush border membrane. Biochim. Biophys. Acta 1486:243-52
-
(2000)
Biochim. Biophys. Acta
, vol.1486
, pp. 243-252
-
-
Detmers, P.A.1
Patel, S.2
Hernandez, M.3
Montenegro, J.4
Lisnock, J.M.5
-
108
-
-
0037783980
-
Intestinal cholesterol absorption: Identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane
-
Kramer W, Girbig F, Corsiero D, Burger K, Fahrenholz F, et al. 2003. Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane. Biochim. Biophys. Acta 1633:13-26
-
(2003)
Biochim. Biophys. Acta
, vol.1633
, pp. 13-26
-
-
Kramer, W.1
Girbig, F.2
Corsiero, D.3
Burger, K.4
Fahrenholz, F.5
-
109
-
-
19944431827
-
Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane
-
Kramer W, Girbig F, Corsiero D, Pfenninger A, Frick W, et al. 2005. Aminopeptidase N (CD13) is a molecular target of the cholesterol absorption inhibitor ezetimibe in the enterocyte brush border membrane. J. Biol. Chem. 280:1306-20
-
(2005)
J. Biol. Chem
, vol.280
, pp. 1306-1320
-
-
Kramer, W.1
Girbig, F.2
Corsiero, D.3
Pfenninger, A.4
Frick, W.5
-
110
-
-
33645912053
-
Ezetimib influences the expression of raft-associated antigens in human monocytes
-
Orso E, Werner T, Wolf Z, Bandulik S, Kramer W, Schmitz G. 2006. Ezetimib influences the expression of raft-associated antigens in human monocytes. Cytometry 69A:206-8
-
(2006)
Cytometry
, vol.69 A
, pp. 206-208
-
-
Orso, E.1
Werner, T.2
Wolf, Z.3
Bandulik, S.4
Kramer, W.5
Schmitz, G.6
-
111
-
-
0032559005
-
Identification of a receptor mediating absorption of dietary cholesterol in the intestine
-
Hauser H, Dyer JH, Nandy A, Vega MA, Werder M, et al. 1998. Identification of a receptor mediating absorption of dietary cholesterol in the intestine. Biochemistry 37:17843-50
-
(1998)
Biochemistry
, vol.37
, pp. 17843-17850
-
-
Hauser, H.1
Dyer, J.H.2
Nandy, A.3
Vega, M.A.4
Werder, M.5
-
112
-
-
0034977594
-
Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine
-
Cai SF, Kirby RJ, Howles PN, Hui DY. 2001. Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine. J. Lipid Res. 42:902-9
-
(2001)
J. Lipid Res
, vol.42
, pp. 902-909
-
-
Cai, S.F.1
Kirby, R.J.2
Howles, P.N.3
Hui, D.Y.4
-
113
-
-
20244372520
-
Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice
-
Mardones P, Quinones V, Amigo L, Moreno M, Miquel JF, et al. 2001. Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. J. Lipid Res. 42:170-80
-
(2001)
J. Lipid Res
, vol.42
, pp. 170-180
-
-
Mardones, P.1
Quinones, V.2
Amigo, L.3
Moreno, M.4
Miquel, J.F.5
-
114
-
-
0037196569
-
The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption
-
Altmann SW, Davis HRJ Yao X, Laverty M, Compton DS, et al. 2002. The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption. Biochim. Biophys. Acta 1580:77-93
-
(2002)
Biochim. Biophys. Acta
, vol.1580
, pp. 77-93
-
-
Altmann, S.W.1
Davis, H.R.J.2
Yao, X.3
Laverty, M.4
Compton, D.S.5
-
115
-
-
0037062952
-
Susceptibility to murine cholesterol gallstone formation is not affected by partial disruption of the HDL receptor SR-BI
-
Wang DQH, Carey MC. 2002. Susceptibility to murine cholesterol gallstone formation is not affected by partial disruption of the HDL receptor SR-BI. Biochim, Biophys. Acta 1583:141-50
-
(2002)
Biochim, Biophys. Acta
, vol.1583
, pp. 141-150
-
-
Wang, D.Q.H.1
Carey, M.C.2
-
116
-
-
0034284918
-
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
-
Repa JJ, Turley SD, Lobaccaro JA, Medina J, Li L, et al. 2000. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers. Science 289:1524-29
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
Turley, S.D.2
Lobaccaro, J.A.3
Medina, J.4
Li, L.5
-
117
-
-
0343717914
-
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
-
McNeish J, Aiello RJ, Guyot D, Turi T, Gabel C, et al. 2000. High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1. Proc. Natl. Acad. Sci. USA 97:4245-50
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4245-4250
-
-
McNeish, J.1
Aiello, R.J.2
Guyot, D.3
Turi, T.4
Gabel, C.5
-
118
-
-
0035084652
-
ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism
-
Drobnik W, Lindenthal B, Lieser B, Ritter M, Weber TC, et al. 2001. ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism. Gastroenterology 120:1203-11
-
(2001)
Gastroenterology
, vol.120
, pp. 1203-1211
-
-
Drobnik, W.1
Lindenthal, B.2
Lieser, B.3
Ritter, M.4
Weber, T.C.5
-
119
-
-
0037072809
-
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1
-
Plosch T, Kok T, Bloks VW, Smit MJ, Havinga R, et al. 2002. Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1. J. Biol. Chem. 277:33870-77
-
(2002)
J. Biol. Chem
, vol.277
, pp. 33870-33877
-
-
Plosch, T.1
Kok, T.2
Bloks, V.W.3
Smit, M.J.4
Havinga, R.5
-
120
-
-
0037903046
-
ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens
-
Mulligan JD, Flowers MT, Tebon A, Bitgood JJ, Wellington C, et al. 2003. ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens. J. Biol. Chem. 278:13356-66
-
(2003)
J. Biol. Chem
, vol.278
, pp. 13356-13366
-
-
Mulligan, J.D.1
Flowers, M.T.2
Tebon, A.3
Bitgood, J.J.4
Wellington, C.5
-
121
-
-
0036795740
-
Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken
-
Attie AD, Hamon Y, Brooks-Wilson AR, Gray-Keller MP, MacDonald ML, et al. 2002. Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken. J. Lipid Res. 43:1610-17
-
(2002)
J. Lipid Res
, vol.43
, pp. 1610-1617
-
-
Attie, A.D.1
Hamon, Y.2
Brooks-Wilson, A.R.3
Gray-Keller, M.P.4
MacDonald, M.L.5
-
122
-
-
0035095882
-
Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues
-
Lawn RM, Wade DP, Couse TL, Wilcox JN. 2001. Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues. Arterioscler. Thromb. Vasc. Biol. 21:378-85
-
(2001)
Arterioscler. Thromb. Vasc. Biol
, vol.21
, pp. 378-385
-
-
Lawn, R.M.1
Wade, D.P.2
Couse, T.L.3
Wilcox, J.N.4
-
123
-
-
0036099122
-
Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans
-
Ostlund REJ, Racette SB, Okeke A, Stenson WF. 2002. Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans. Am. J. Clin. Nutr. 75:1000-4
-
(2002)
Am. J. Clin. Nutr
, vol.75
, pp. 1000-1004
-
-
Ostlund, R.E.J.1
Racette, S.B.2
Okeke, A.3
Stenson, W.F.4
-
124
-
-
0027729980
-
Comparison of intestinal absorption of cholesterol with different plant sterols in man
-
Heinemann T, Axtmann G, von Bergmann K. 1993. Comparison of intestinal absorption of cholesterol with different plant sterols in man. Eur. J. Clin. Invest. 23:827-31
-
(1993)
Eur. J. Clin. Invest
, vol.23
, pp. 827-831
-
-
Heinemann, T.1
Axtmann, G.2
von Bergmann, K.3
-
125
-
-
0033804429
-
Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet
-
Hallikainen MA, Sarkkinen ES, Gylling H, Erkkila AT, Uusitupa MI. 2000. Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet. Eur. J. Clin. Nutr. 54:715-25
-
(2000)
Eur. J. Clin. Nutr
, vol.54
, pp. 715-725
-
-
Hallikainen, M.A.1
Sarkkinen, E.S.2
Gylling, H.3
Erkkila, A.T.4
Uusitupa, M.I.5
-
126
-
-
0036083573
-
Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion
-
Nissinen M, Gylling H, Vuoristo M, Miettinen TA. 2002. Micellar distribution of cholesterol and phytosterols after duodenal plant stanol ester infusion. Am. J. Physiol. 282:G1009-15
-
(2002)
Am. J. Physiol
, vol.282
-
-
Nissinen, M.1
Gylling, H.2
Vuoristo, M.3
Miettinen, T.A.4
-
127
-
-
0024452728
-
Effects of sitosterol and sitostanol on micellar solubility of cholesterol
-
Ikeda I, Tanabe Y, Sugano M. 1989. Effects of sitosterol and sitostanol on micellar solubility of cholesterol. J. Nutr. Sci. Vitaminol. 35:361-69
-
(1989)
J. Nutr. Sci. Vitaminol
, vol.35
, pp. 361-369
-
-
Ikeda, I.1
Tanabe, Y.2
Sugano, M.3
-
128
-
-
0024264706
-
Discrimination between cholesterol and sitosterol for absorption in rats
-
Ikeda I, Tanaka K, Sugano M, Vahouny GV, Gallo LL. 1988. Discrimination between cholesterol and sitosterol for absorption in rats. J. Lipid Res. 29:1583-91
-
(1988)
J. Lipid Res
, vol.29
, pp. 1583-1591
-
-
Ikeda, I.1
Tanaka, K.2
Sugano, M.3
Vahouny, G.V.4
Gallo, L.L.5
-
129
-
-
0024210833
-
Inhibition of cholesterol absorption in rats by plant sterols
-
Ikeda I, Tanaka K, Sugano M, Vahouny GV, Gallo LL. 1988. Inhibition of cholesterol absorption in rats by plant sterols. J. Lipid Res. 29:1573-82
-
(1988)
J. Lipid Res
, vol.29
, pp. 1573-1582
-
-
Ikeda, I.1
Tanaka, K.2
Sugano, M.3
Vahouny, G.V.4
Gallo, L.L.5
-
130
-
-
0036482333
-
Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women
-
Plat J, Mensink RP. 2002. Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women. FASEB J. 16:258-60
-
(2002)
FASEB J
, vol.16
, pp. 258-260
-
-
Plat, J.1
Mensink, R.P.2
-
131
-
-
0036424159
-
Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia
-
Sudhop T, von Bergmann K. 2002. Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia. Drugs 62:2333-47
-
(2002)
Drugs
, vol.62
, pp. 2333-2347
-
-
Sudhop, T.1
von Bergmann, K.2
-
132
-
-
9544237127
-
2-Azetidinone cholesterol absorption inhibitors: Structure-activity relationships on the heterocyclic nucleus
-
Clader JW, Burnett DA, Caplen MA, Domalski MS, Dugar S, et al. 1996. 2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus. J. Med. Chem. 39:3684-93
-
(1996)
J. Med. Chem
, vol.39
, pp. 3684-3693
-
-
Clader, J.W.1
Burnett, D.A.2
Caplen, M.A.3
Domalski, M.S.4
Dugar, S.5
-
133
-
-
0030848734
-
In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461
-
van Heek M, France CF, Compton DS, McLeod RL, Yumibe NP, et al. 1997. In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461. J. Pharmacol. Exp. Ther. 283:157-63
-
(1997)
J. Pharmacol. Exp. Ther
, vol.283
, pp. 157-163
-
-
van Heek, M.1
France, C.F.2
Compton, D.S.3
McLeod, R.L.4
Yumibe, N.P.5
-
134
-
-
0034985134
-
A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe
-
Ezzet F, Krishna G, Wexler DB, Statkevich P, Kosoglou T, Batra VK. 2001. A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe. Clin. Ther. 23:871-85
-
(2001)
Clin. Ther
, vol.23
, pp. 871-885
-
-
Ezzet, F.1
Krishna, G.2
Wexler, D.B.3
Statkevich, P.4
Kosoglou, T.5
Batra, V.K.6
-
135
-
-
0344490262
-
Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial
-
Melani L, Mills R, Hassman D, Lipetz R, Lipka L, et al. 2003. Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Eur. Heart J. 24:717-28
-
(2003)
Eur. Heart J
, vol.24
, pp. 717-728
-
-
Melani, L.1
Mills, R.2
Hassman, D.3
Lipetz, R.4
Lipka, L.5
-
136
-
-
2942574385
-
Treatment of high-risk patients with ezetimibe plus simvastatin coadministration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals
-
Feldman T, Koren M, Insull WJ, McKenney J, Schrott H, et al. 2004. Treatment of high-risk patients with ezetimibe plus simvastatin coadministration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III low-density lipoprotein cholesterol goals. Am. J. Cardiol. 93:1481-86
-
(2004)
Am. J. Cardiol
, vol.93
, pp. 1481-1486
-
-
Feldman, T.1
Koren, M.2
Insull, W.J.3
McKenney, J.4
Schrott, H.5
-
137
-
-
0037188567
-
Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia
-
Gagne C, Gaudet D, Bruckert E. 2002. Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia. Circulation 105:2469-75
-
(2002)
Circulation
, vol.105
, pp. 2469-2475
-
-
Gagne, C.1
Gaudet, D.2
Bruckert, E.3
-
138
-
-
1442335817
-
Multicenter Sitosterolemia Study Group. Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia
-
Salen G, von Bergmann K, Lutjohann D, Kwiterovich P, Kane J, et al. 2004. Multicenter Sitosterolemia Study Group. Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia. Circulation 109:966-71
-
(2004)
Circulation
, vol.109
, pp. 966-971
-
-
Salen, G.1
von Bergmann, K.2
Lutjohann, D.3
Kwiterovich, P.4
Kane, J.5
-
139
-
-
33947368920
-
-
Arzneimittelkommission der deutschen Äerzteschaft. 2004. Myopathien bzw. Leberreaktionen unter Ezetimib (Ezetrol). Deutsches. Aerzteblatt. 101:A959 (Abstr.)
-
Arzneimittelkommission der deutschen Äerzteschaft. 2004. Myopathien bzw. Leberreaktionen unter Ezetimib (Ezetrol). Deutsches. Aerzteblatt. 101:A959 (Abstr.)
-
-
-
-
140
-
-
0021912469
-
Effects of the degree of saturation of dietary fat on the hepatic production of lipoproteins in the African green monkey
-
Johnson FL, St Clair RW, Rudel LL. 1985. Effects of the degree of saturation of dietary fat on the hepatic production of lipoproteins in the African green monkey. J. Lipid Res. 26:403-17
-
(1985)
J. Lipid Res
, vol.26
, pp. 403-417
-
-
Johnson, F.L.1
St Clair, R.W.2
Rudel, L.L.3
-
141
-
-
0023598027
-
Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats
-
Chen IS, Hotta SS, Ikeda I, Cassidy MM, Sheppard AJ, Vahouny GV 1987. Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats. J. Nutr. 117:1676-80
-
(1987)
J. Nutr
, vol.117
, pp. 1676-1680
-
-
Chen, I.S.1
Hotta, S.S.2
Ikeda, I.3
Cassidy, M.M.4
Sheppard, A.J.5
Vahouny, G.V.6
-
142
-
-
0036202294
-
Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers
-
Eckhardt ER, Wang DQH, Donovan JM, Carey MC. 2002. Dietary sphingomyelin suppresses intestinal cholesterol absorption by decreasing thermodynamic activity of cholesterol monomers. Gastroenterology 122:948-56
-
(2002)
Gastroenterology
, vol.122
, pp. 948-956
-
-
Eckhardt, E.R.1
Wang, D.Q.H.2
Donovan, J.M.3
Carey, M.C.4
-
143
-
-
0018129663
-
Dietary fiber and lymphatic absorption of cholesterol in the rat
-
Vahouny GV, Roy T, Gallo LL, Story JA, Kritchevsky D, et al. 1978. Dietary fiber and lymphatic absorption of cholesterol in the rat. Am. J. Clin. Nutr. 31:S208-10
-
(1978)
Am. J. Clin. Nutr
, vol.31
-
-
Vahouny, G.V.1
Roy, T.2
Gallo, L.L.3
Story, J.A.4
Kritchevsky, D.5
-
144
-
-
0031705644
-
Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia
-
Schwarz M, Russell DW, Dietschy JM, Turley SD. 1998. Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia. J. Lipid Res. 39:1833-43
-
(1998)
J. Lipid Res
, vol.39
, pp. 1833-1843
-
-
Schwarz, M.1
Russell, D.W.2
Dietschy, J.M.3
Turley, S.D.4
-
145
-
-
23044498557
-
Caveolin-1 is not required for murine intestinal cholesterol transport
-
Valasek MA, Weng J, Shaul PW, Anderson RG, Repa JJ. 2005. Caveolin-1 is not required for murine intestinal cholesterol transport. J. Biol. Chem. 280:28103-9
-
(2005)
J. Biol. Chem
, vol.280
, pp. 28103-28109
-
-
Valasek, M.A.1
Weng, J.2
Shaul, P.W.3
Anderson, R.G.4
Repa, J.J.5
-
146
-
-
15644365767
-
Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice
-
Weinstock PH, Bisgaier CL, Hayek T, Aalto-Setala K, Sehayek E, et al. 1997. Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice. J. Lipid Res. 38:1782-94
-
(1997)
J. Lipid Res
, vol.38
, pp. 1782-1794
-
-
Weinstock, P.H.1
Bisgaier, C.L.2
Hayek, T.3
Aalto-Setala, K.4
Sehayek, E.5
-
147
-
-
0028327242
-
Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior
-
Aalto-Setala K, Bisgaier CL, Ho A, Kieft KA, Traber MG, et al. 1994. Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior. J. Clin. Invest. 93:1776-86
-
(1994)
J. Clin. Invest
, vol.93
, pp. 1776-1786
-
-
Aalto-Setala, K.1
Bisgaier, C.L.2
Ho, A.3
Kieft, K.A.4
Traber, M.G.5
-
148
-
-
0344236149
-
Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice
-
Knight BL, Patel DD, Humphreys SM, Wiggins D, Gibbons GF. 2003. Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice. J. Lipid Res. 44:2049-58
-
(2003)
J. Lipid Res
, vol.44
, pp. 2049-2058
-
-
Knight, B.L.1
Patel, D.D.2
Humphreys, S.M.3
Wiggins, D.4
Gibbons, G.F.5
-
149
-
-
22344449773
-
Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1
-
van der Veen JN, Kruit JK, Havinga R, Baller JF, Chimini G, et al. 2005. Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1. Lipid Res. 46:526-34
-
(2005)
Lipid Res
, vol.46
, pp. 526-534
-
-
van der Veen, J.N.1
Kruit, J.K.2
Havinga, R.3
Baller, J.F.4
Chimini, G.5
-
150
-
-
0842304653
-
Rate of gastric emptying influences dietary cholesterol absorption efficiency in selected inbred strains of mice
-
Kirby RJ, Howies PN, Hui DY. 2004. Rate of gastric emptying influences dietary cholesterol absorption efficiency in selected inbred strains of mice. J. Lipid Res. 45:89-98
-
(2004)
J. Lipid Res
, vol.45
, pp. 89-98
-
-
Kirby, R.J.1
Howies, P.N.2
Hui, D.Y.3
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