Flavonoid engineering of flax potentiate its biotechnological application

BMC Biotechnology

Volumn 11, Issue , 2011, Pages

  Zuk, Magdalena ^a,e   Kulma, Anna ^a   Dymińska, Lucyna ^b   Szołtysek, Katarzyna ^b   Prescha, Anna ^c   Hanuza, Jerzy ^b,d   Szopa, Jan ^a,e  

^a UNIVERSITY OF WROC AW   (Poland)

^b WROCLAW UNIVERSITY OF ECONOMICS   (Poland)

^c WROCLAW MEDICAL UNIVERSITY   (Poland)

^d INSTITUTE OF LOW TEMPERATURE AND STRUCTURE RESEARCH   (Poland)

^e Linum Fundation   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS RESULTS; ANTIOXIDANT COMPOUNDS; BIOCHEMICAL ANALYSIS; BIOCHEMICAL DATA; BIOCHEMICAL PROPERTIES; BIOMEDICAL APPLICATIONS; BIOTECHNOLOGICAL APPLICATIONS; BREAST CANCER; CELLULOSE POLYMERS; FT-IR STUDY; IN-FIELD; INFLAMMATORY REACTION; IR BANDS; IR SPECTROSCOPY; KAEMPFEROL; LIGNANS; PHENOLIC ACIDS; PHENYLPROPANOID PATHWAYS; PLANT GROWTH; PLANT MATERIAL; PLANT METABOLITES; PROTECTIVE EFFECTS; SEED MATURATION; THIRD GENERATION; TRANSGENIC PLANTS; TRANSGENIC SEEDS; TRANSGENICS;

DISEASES; FATTY ACIDS; FIBERS; FLAVONOIDS; FLAX; FUNCTIONAL POLYMERS; GENES; GENETIC ENGINEERING; HYDROGEN BONDS; INFRARED SPECTROSCOPY; LINEN; METABOLITES; ORGANIC ACIDS; PHENOLS; SEED; SPECTRUM ANALYSIS; YARN;

PLANT EXTRACTS;

ANTIOXIDANT; CATECHIN; CELLULOSE; COUMARIC ACID; FATTY ACID; FERULIC ACID; FLAVONOID; KAEMPFEROL; LIGNAN; OIL; PLANT EXTRACT; POLYMER; METHANOL; PEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; VEGETABLE OIL;

ARTICLE; BIOCHEMISTRY; BIOMEDICAL ENGINEERING; CHEMICAL ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; FLAX; GENE EXPRESSION; HYDROGEN BOND; INFRARED SPECTROSCOPY; LIPID STORAGE; MATURATION; MEDICAL RECORD; NONHUMAN; OXIDATION; PLANT SEED; TRANSGENE; CHEMISTRY; GENETIC ENGINEERING; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROPHOTOMETRY; METABOLISM; METHODOLOGY; SCANNING ELECTRON MICROSCOPY; TRANSGENIC PLANT;

LINUM USITATISSIMUM;

CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOIDS; FLAX; GENETIC ENGINEERING; METHANOL; MICROSCOPY, ELECTRON, SCANNING; PEROXIDES; PLANT OILS; PLANTS, GENETICALLY MODIFIED; SEEDS; SPECTROPHOTOMETRY, INFRARED; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 79251577092     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-11-10     Document Type: Article

References (58)

1. Huang S, Milles DE. Gamma-linolenic acid: Metabolism and its roles in nutrition and medicine. 1996,
2. Huang S, Ziboh A. Gamma-linolenic acid: Recent advances in biotechnology and clinical applications. 2001, Champaign IAP.
3. Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine and Pharmacotheraphy 2002, 56:365-379.
4. Dribnenki J, Green AG. Linola 947- low linolenic flax. Canadian Journal of Plant Science 1995, 75:201-202.
5. Green AG. A mutant genotype of flax (Linum usitatissimum L.) containing very low levels of linolenic acid in its seed oil. Canadian Journal of Plant Science 1986, 66:499-503.
6. Czemplik M, Szopa J. Optimizing biomedical and industrial products development based on flax. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources 2009, 4(062).
7. Skórkowska-Telichowska K, Zuk M, Kulma A, Bugajska-Prusak A, Ratajczak K, Ga{ogonek}siorowski K, Kostyn K, Szopa J. New dressing materials derived from transgenic flax products to treat long-standing venous ulcers--a pilot study. Wound Repair and Regeneration 2010, 18:168-179.
8. Holton TA, Cornish E. Genetic and biochemistry of anthocyanin biosynthesis. Plant Cell 1995, 7:1071-1083. 10.1105/tpc.7.7.1071, 160913, 12242398.
9. Martens S, Mithöfer A. Flavones and flavone synthases. Phytochemistry 2005, 66:2399-2407. 10.1016/j.phytochem.2005.07.013, 16137727.
10. Winkel-Shirley B. Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology. Plant Physiol 2001, 126:485-493. 10.1104/pp.126.2.485, 1540115, 11402179.
11. Pietta PG. Flavonoids as Antioxidants. J Nat Prod 2000, 63:1035-1042. 10.1021/np9904509, 10924197.
12. Harborne JB, Williams C. Advances in flavonoids research since 1992. Phytochemistry 2000, 55:481-504. 10.1016/S0031-9422(00)00235-1, 11130659.
13. Cushni PT, Lamb A. Antimicrobial activity of flavonoids. Int J Antimicrob Agents 2005, 26:343-356. 10.1016/j.ijantimicag.2005.09.002, 16323269.
14. Ryan KG, Swinny EE, Markham KR, Winefield C. Flavonoid gene expression and UV photoprotection in transgenic and mutant Petunia leaves. Phytochemistry 2002, 59:23-32. 10.1016/S0031-9422(01)00404-6, 11754940.
15. Lee JH, Shim JS, Lee JS, Kim JK, Yang IS, Chung MS, Kim KH. Inhibition of pathogenic bacterial adhesion by acidic polysaccharide from green tea (Camellia sinensis). J Agric Food Chem 2006, 54:8717-8723. 10.1021/jf061603i, 17090112.
16. Arora A, Muraleedharan GN, Strasburg GM. Structure activity relationships for antioxidant activities of a series of flavonoids in a liposomal system. Free Radical Biol Med 1998, 9:1355-1363.
17. Lorenc-Kukuła K, Amarowicz R, Oszmiański J, Doermann P, Starzyki M, Skała J, Żuk M, Kulma A, Szopa J. Pleiotropic Effect of Phenolic Compounds Content Increases in Transgenic Flax Plant. J Agric Food Chem 2005, 53:3685-3692.
18. Prescha A, Siger A, Lorenc-Kukuła K, Biernat J, Nogala-Kałucka M, Szopa J. Badania nad składem i podatnościa{ogonek} na utlenianie oleju z nasion lnu modyfikowanego genetycznie. BROMAT.CHEM.TOKSYKOL 2008, XLI:286-292.
19. Lukaszewicz M, Matysiak-Kata I, Skała J, Fecka I, Cisowski W, Szopa J. Antioxidant capacity manipulation in transgenic potato tuber by changes in phenolic compounds content. Agric Food Chem 2004, 52:1526-1533.
20. Wróbel M, Zebrowski J, Szopa J. Polyhydroxybutyrate synthesis in transgenic flax. J.Biotech 2004, 107:41-54.
21. Logemann J, Schell J, Willmitzer L. A rapid method for the isolation of RNA from plant tissue. Anal Biochem 1987, 163:21-26. 10.1016/0003-2697(87)90086-8, 3039867.
22. Prescha A, Świe{ogonek}drych A, Biernat J, Szopa J. Increase in lipid content inpotato tubers modified by 14-3-3 gene overexpression. J Agric Food Chem 2001, 49:3638-3643. 10.1021/jf010258o, 11513640.
23. Naczk M, Shahidi F. Extraction and analysis of phenolics in food. J Chromatogr A 2004, 1054:95-111.
24. Velasco L, Goffman D. Tocopherol,plastochromanol and fatty acid patterns in the genus Linum. Plant Syst Evol 2000, 221:77-88.
25. Lorenc-Kukuła K, Zuk M, Kulma A, Czemplik M, Kostyn K, Skala J, Starzycki M, Szopa J. Enginiering flax with the GT Family I Solanum sogerandinum gycosyltransferase SsGT1 Confers Increased Resistance to Fusarium Infection. J Agric Food Chem 2009, 57(15):6698-6705.
26. Lukaszewicz M, Matysiak-Kata I, Aksamit A, Oszmianski J, Szopa J. 14-3-3 Protein regulation of the antioxidant capacity of transgenic potato tubers. Plant Sci 2002, 163:125-130.
27. Wróbel-Kwiatkowska M, Starzycki M, Żebrowski J, Oszmiański J, Szopa J. Engineering of PHB synthesis causes improved elastic properties of flax fibers. Biotechnol Prog 2007, 23:269-277.
28. Updegraff D. Semimicro determination of cellulose in biological materials. Anal Biochem 1969, 32:420-424. 10.1016/S0003-2697(69)80009-6, 5361396.
29. Iiyama K, Wallis A. Determination of lignin in herbaceous plants by an improved acetyl bromide procedure. J Food Sci and Agri 1990, 51:145-161.
30. Melton LD, Smith G. Isolation of cell wall and fractionation of cell wall polysaccharides. 2001,
31. Lorenc-Kukula K, Jafra S, Oszmianski J, Szopa J. Ectopic Expression of Anthocyanin 5-O-Glucosyltransferase in Potato Tuber Causes Increased Resistance to Bacteria. J Agric Food Chem 2005, 53:272-281. 10.1021/jf048449p, 15656661.
32. Lukaszewicz M, Szopa J, Krasowska A. Susceptibility of lipids from different flax cultivars to peroxidation and its lowering by added antioxidants. Food Chem 2004, 88:225-231.
33. Di Candilo M, Ranalli P, Bozzi C, Focher B, Mastromei G. Preliminary results of tests facing with the controlled retting of hemp. Industrial Crops and Products 2000, 11:197-203.
34. Easson LD, Molloy R. Retting-a key process in the production of high value fibre from flax. Outlook Agric 1996, 25:235-242.
35. Günzler H, Gremlich U. IR Spectroscopy. An Introduction, Wiley-VCh, Weinheim, Germany. 2002, Chapter 6.4:178.
36. Ram MS, Dowell FE, Seitz LM. FT-Raman spectra of unsoaked and NaOH-soaked wheat kernels, bran, and ferulic acid. Cereall Chemistry 2003, 80:188.
37. Sebastian S, Sundaraganesan N, Manoharan S. Molecular structure, spectroscopic studies and first-order molecular hyperpolarizabilities of ferulic acid by density functional study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2009, 74:312.
38. Socrates G. Infrared and Raman Characteristic Group Frequencies. 2001, Chapter 2:50. J Wiley & Sons, Ltd, Chichester, New York, Weinheim, Toronto, Brisbane, Singapore, third.
39. Wojtkowiak B, Chabanel M. Spectrochimie Moleculaire, Technique et Documentation. 1984, Chapter 4:114. Warszawa: PWN.
40. Zuk M, Dymińska L, Kulma A, Prescha A, Szopa J, Ma{ogonek}czka M, Szołtysek K, Hanuza J. IR and Raman studies of oil and seedcake extracts from natural and genetically modified flax seeds. Spectrochemica Acta Part A 2010,
41. Edwards HGM, Farwell DW, Webster D. Raman microscopy of untreated natural plant fibres. Spectrochimica Acta Part A 1997, 53:2383-2392.
42. Jahn A, Schroder MW, Futing M, Schenzel K, Diepenbrock W. Characterization of alkali treated flax fibres by means of FT Raman spectroscopy and environmental scanning electron microscopy. Spectrochim Acta Part A 2002, 58:2271-2279.
43. Wróbel-Kwiatkowska M, Szopa J, Dymińska L, Ma{ogonek}czka M, Hanuza J. Poly-3-hydroxy butyric acid interaction with the transgenic flax fibers: FT-IR and Raman spectra of the composite extracted from a GM flax. Biotechnology Progress 2009, 25:1489-1498.
44. Boeriu CG, Bravo D, Gosselink RJA, van Dam JEG. Characerisation of structure-dependent functional properties of lignin with infrared spectroscopy. Industr Crops and Prod 2004, 20:205.
45. Wróbel-Kwiatkowska M, Żuk M, Szopa J, Dymińska L, Ma{ogonek}czka M, Hanuza J. Poly-3-hydroxy butyric acid interaction with the transgenic flax fibers: FT-IR and Raman spectra of the composite extracted from a GM flax. Spectrochimica Acta Part A 2009, 73:286-294.
46. Htoo JK, Meng X, Patience JF, Dugan ME, Zijlstra RT. Effects of coextrusion of flaxseed and field pea on the digestibility of energy, ether extract, fatty acids, protein, and amino acids in grower-finisher pigs. J Anim Sci 2008, 86(11):2942-2951. 10.2527/jas.2007-0313, 18599674.
47. Bledzki AK, Faruk O, Sperber VE. Cars from Bio-Fibres. Macromol Mater Eng 2006, 291:449-457.
48. Schijlen EG, Ric de Vos CH, van Tunen AJ, Bovy AG. Modification of flavonoid biosynthesis in crop plants. Phytochemistry 2004, 65:2631-2648. 10.1016/j.phytochem.2004.07.028, 15464151.
49. Adlercreutz H. Phytoestrogens and cancer. Lancet Oncol 2002, 3:364-373. 10.1016/S1470-2045(02)00777-5, 12107024.
50. Besseau S, Hoffman L, Geoffroy P, Lapierre C, Pollet B, Legrand M. Flavonoid accumulation in Arabidopsis repressed in lignin synthesis affects auxin transport and plant growth. Plant Cell 2007, 19(1):148-162. 10.1105/tpc.106.044495, 1820963, 17237352.
51. Donaldson MS. Nutrition and cancer: a review of the evidence for an anti-cancer diet. NutrJ 2004, 3(19).
52. Sung MK, Lautens M, Thompson LU. Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. Anticancer res 1998, 18:1405-1408.
53. Saffron A, Whitehead SR. Phytoestrogens oestrogen synthesis and breast cancer. Journal of Steroid Biochemistry & Molecular Biology 2008, 108:186-195.
54. Westcott ND, Muir AD. Flax seed lignan in disease prevention and health promotion. Phytochem ReV 2003, 2:401-417.
55. Arts ICV, Hollman PCH. Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr 2005, 81:S317-S325.
56. Loh PS, Miller A, Reeves AD, Harvey SM, Overnell J. Optimised recovery of lignin-derived phenols in a Scottish fjord by the CuO oxidation method. J Environ Monit 2008, 10(10):1187-1194. 10.1039/b808970a, 19244642.
57. Prasad K. Secoizolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. Journal of Laboratory and Clinical Medicine 2001, 138(1):32-39. 10.1067/mlc.2001.115717, 11433226.
58. Prasad K. Oxidative stress as a mechanism of diabetes in diabetic BB prone rats: Effect of secoisolariciresinol diglucoside (SDG). Molecullar and Cellular Biochemistry 2000, 209:89-96.