메뉴 건너뛰기




Volumn 30, Issue 1, 2013, Pages 12-25

Molecular pathways and cellular metabolism in colorectal cancer

Author keywords

Adenoma; Biomarker; Colorectal cancer; Genetics; Metabolism; Molecular classification; Mutations; Prediction; Prognosis

Indexed keywords

TUMOR MARKER;

EID: 84876075247     PISSN: 02534886     EISSN: None     Source Type: Journal    
DOI: 10.1159/000347166     Document Type: Review
Times cited : (52)

References (125)
  • 1
    • 84869492886 scopus 로고    scopus 로고
    • Global burden of cancer in 2008: A systematic analysis of disability-Adjusted life-years in 12 world regions
    • Soerjomataram I, Lortet-Tieulent J, Parkin DM, Ferlay J, Mathers C, Forman D, Bray F: Global burden of cancer in 2008: A systematic analysis of disability-Adjusted life-years in 12 world regions. Lancet 2012; 380: 1840-1850
    • (2012) Lancet , vol.380 , pp. 1840-1850
    • Soerjomataram, I.1    Lortet-Tieulent, J.2    Parkin, D.M.3    Ferlay, J.4    Mathers, C.5    Forman, D.6    Bray, F.7
  • 3
    • 84859241733 scopus 로고    scopus 로고
    • Advances in the understanding and treatment of colorectal cancer
    • Soreide K, Berg M, Skudal BS, Nedrebo BS: Advances in the understanding and treatment of colorectal cancer. Discov Med 2011; 12: 393-404
    • (2011) Discov Med , vol.12 , pp. 393-404
    • Soreide, K.1    Berg, M.2    Skudal, B.S.3    Nedrebo, B.S.4
  • 4
    • 79953680733 scopus 로고    scopus 로고
    • Survival effect of implementing national treatment strategies for curatively resected colonic and rectal cancer
    • Nedrebo BS, Soreide K, Eriksen MT, Dorum LM, Kvaloy JT, Soreide JA, Korner H: Survival effect of implementing national treatment strategies for curatively resected colonic and rectal cancer. Br J Surg 2011; 98: 716-723
    • (2011) Br J Surg , vol.98 , pp. 716-723
    • Nedrebo, B.S.1    Soreide, K.2    Eriksen, M.T.3    Dorum, L.M.4    Kvaloy, J.T.5    Soreide, J.A.6    Korner, H.7
  • 7
    • 84860313256 scopus 로고    scopus 로고
    • Detection of DNA hypermethylation in remote media of patients with colorectal cancer: New biomarkers for colorectal carcinoma
    • Herbst A, Kolligs FT: Detection of DNA hypermethylation in remote media of patients with colorectal cancer: New biomarkers for colorectal carcinoma. Tumour Biol 2012; 33: 297-305
    • (2012) Tumour Biol , vol.33 , pp. 297-305
    • Herbst, A.1    Kolligs, F.T.2
  • 8
    • 79960262064 scopus 로고    scopus 로고
    • Colorectal cancer screening
    • Bretthauer M: Colorectal cancer screening. J Intern Med 2011; 270: 87-98
    • (2011) J Intern Med , vol.270 , pp. 87-98
    • Bretthauer, M.1
  • 9
    • 36448940917 scopus 로고    scopus 로고
    • Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers-ready for prime time?
    • Soreide K: Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers-ready for prime time? Tumour Biol 2007; 28: 290-300
    • (2007) Tumour Biol , vol.28 , pp. 290-300
    • Soreide, K.1
  • 10
    • 84864049574 scopus 로고    scopus 로고
    • Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy
    • Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT: Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy. Lancet 2012; 380: 219- 229
    • (2012) Lancet , vol.380 , pp. 219-229
    • Lee, I.M.1    Shiroma, E.J.2    Lobelo, F.3    Puska, P.4    Blair, S.N.5    Katzmarzyk, P.T.6
  • 11
    • 78649925012 scopus 로고    scopus 로고
    • Physical activity and gastrointestinal cancer prevention
    • Wolin KY, Tuchman H: Physical activity and gastrointestinal cancer prevention. Recent Results Cancer Res 2011; 186: 73-100
    • (2011) Recent Results Cancer Res , vol.186 , pp. 73-100
    • Wolin, K.Y.1    Tuchman, H.2
  • 12
    • 82955165002 scopus 로고    scopus 로고
    • Timing and intensity of recreational physical activity and the risk of subsite-specific colorectal cancer
    • Boyle T, Heyworth J, Bull F, McKerracher S, Platell C, Fritschi L: Timing and intensity of recreational physical activity and the risk of subsite-specific colorectal cancer. Cancer Causes Control 2011; 22: 1647-1658
    • (2011) Cancer Causes Control , vol.22 , pp. 1647-1658
    • Boyle, T.1    Heyworth, J.2    Bull, F.3    McKerracher, S.4    Platell, C.5    Fritschi, L.6
  • 13
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB: The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation. Cell Metab 2008; 7: 11-20
    • (2008) Cell Metab , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 14
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA: Hallmarks of cancer: The next generation. Cell 2011; 144: 646- 674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 15
    • 84868019043 scopus 로고    scopus 로고
    • Cancer cell metabolism: One hallmark, many faces
    • Cantor JR, Sabatini DM: Cancer cell metabolism: One hallmark, many faces. Cancer Discov 2012; 2: 881-898
    • (2012) Cancer Discov , vol.2 , pp. 881-898
    • Cantor, J.R.1    Sabatini, D.M.2
  • 16
    • 84865508873 scopus 로고    scopus 로고
    • Proteomics, genomics, and molecular biology in the personalized treatment of colorectal cancer
    • Carethers JM: Proteomics, genomics, and molecular biology in the personalized treatment of colorectal cancer. J Gastrointest Surg 2012; 16: 1648-1650
    • (2012) J Gastrointest Surg , vol.16 , pp. 1648-1650
    • Carethers, J.M.1
  • 20
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer C, Kinzler KW, Vogelstein B: Genetic instability in colorectal cancers. Nature 1997; 386: 623-627
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 21
  • 22
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B: Lessons from hereditary colorectal cancer. Cell 1996; 87: 159- 170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 24
    • 0037108710 scopus 로고    scopus 로고
    • Dissecting karyotypic patterns in colorectal tumors: Two distinct but overlapping pathways in the adenoma-carcinoma transition
    • Hoglund M, Gisselsson D, Hansen GB, Sall T, Mitelman F, Nilbert M: Dissecting karyotypic patterns in colorectal tumors: Two distinct but overlapping pathways in the adenoma-carcinoma transition. Cancer Res 2002; 62: 5939- 5946
    • (2002) Cancer Res , vol.62 , pp. 5939-5946
    • Hoglund, M.1    Gisselsson, D.2    Hansen, G.B.3    Sall, T.4    Mitelman, F.5    Nilbert, M.6
  • 25
    • 84866235428 scopus 로고    scopus 로고
    • Genetic and epigenetic events generate multiple pathways in colorectal cancer progression
    • Pancione M, Remo A, Colantuoni V: Genetic and epigenetic events generate multiple pathways in colorectal cancer progression. Pathol Res Int 2012; 2012: 509348
    • (2012) Pathol Res Int , vol.2012 , pp. 509348
    • Pancione, M.1    Remo, A.2    Colantuoni, V.3
  • 26
    • 39649118620 scopus 로고    scopus 로고
    • Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: Classification, molecular genetics, natural history, and clinical management
    • East JE, Saunders BP, Jass JR: Sporadic and syndromic hyperplastic polyps and serrated adenomas of the colon: Classification, molecular genetics, natural history, and clinical management. Gastroenterol Clin North Am 2008; 37: 25-46
    • (2008) Gastroenterol Clin North Am , vol.37 , pp. 25-46
    • East, J.E.1    Saunders, B.P.2    Jass, J.R.3
  • 28
    • 79751531115 scopus 로고    scopus 로고
    • The American College of Gastroenterology Emily Couric Lecture-The adenoma- carcinoma sequence revisited: Has the era of genetic tailoring finally arrived?
    • Ahnen DJ: The American College of Gastroenterology Emily Couric Lecture-The adenoma- carcinoma sequence revisited: Has the era of genetic tailoring finally arrived? Am J Gastroenterol 2011; 106: 190-198
    • (2011) Am J Gastroenterol , vol.106 , pp. 190-198
    • Ahnen, D.J.1
  • 31
    • 82555189387 scopus 로고    scopus 로고
    • Complex patterns of altered microrna expression during the adenoma-Adenocarcinoma sequence for microsatellitestable colorectal cancer
    • Bartley AN, Yao H, Barkoh BA, Ivan C, Mishra BM, Rashid A, Calin GA, Luthra R, Hamilton SR: Complex patterns of altered microrna expression during the adenoma-Adenocarcinoma sequence for microsatellitestable colorectal cancer. Clin Cancer Res 2011; 17: 7283-7293
    • (2011) Clin Cancer Res , vol.17 , pp. 7283-7293
    • Bartley, A.N.1    Yao, H.2    Barkoh, B.A.3    Ivan, C.4    Mishra, B.M.5    Rashid, A.6    Calin, G.A.7    Luthra, R.8    Hamilton, S.R.9
  • 32
    • 78649985198 scopus 로고    scopus 로고
    • Update on the serrated pathway to colorectal carcinoma
    • Snover DC: Update on the serrated pathway to colorectal carcinoma. Hum Pathol 2011; 42: 1-10
    • (2011) Hum Pathol , vol.42 , pp. 1-10
    • Snover, D.C.1
  • 33
    • 66549090189 scopus 로고    scopus 로고
    • Endoscopy, morphology, morphometry and molecular markers: Predicting cancer risk in colorectal adenoma
    • Soreide K, Nedrebo BS, Reite A, Thorsen K, Korner H: Endoscopy, morphology, morphometry and molecular markers: Predicting cancer risk in colorectal adenoma. Expert Rev Mol Diagn 2009; 9: 125-137
    • (2009) Expert Rev Mol Diagn , vol.9 , pp. 125-137
    • Soreide, K.1    Nedrebo, B.S.2    Reite, A.3    Thorsen, K.4    Korner, H.5
  • 35
    • 60249083789 scopus 로고    scopus 로고
    • Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: Potential implications for the surgical oncologist
    • Soreide K, Nedrebo BS, Knapp JC, Glomsaker TB, Soreide JA, Korner H: Evolving molecular classification by genomic and proteomic biomarkers in colorectal cancer: Potential implications for the surgical oncologist. Surg Oncol 2009; 18: 31-50
    • (2009) Surg Oncol , vol.18 , pp. 31-50
    • Soreide, K.1    Nedrebo, B.S.2    Knapp, J.C.3    Glomsaker, T.B.4    Soreide, J.A.5    Korner, H.6
  • 36
    • 58349085083 scopus 로고    scopus 로고
    • Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research
    • Soreide K: Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research. J Clin Pathol 2009; 62: 1-5.
    • (2009) J Clin Pathol , vol.62 , pp. 1-5
    • Soreide, K.1
  • 37
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B: Genetic instabilities in human cancers. Nature 1998; 396: 643-649
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 39
    • 79958255986 scopus 로고    scopus 로고
    • Identification of chromosome aberrations in sporadic microsatellite stable and unstable colorectal cancers using array comparative genomic hybridization
    • Dyrso T, Li J, Wang K, Lindebjerg J, Kolvraa S, Bolund L, Jakobsen A, Bruun-Petersen G, Li S, Cruger DG: Identification of chromosome aberrations in sporadic microsatellite stable and unstable colorectal cancers using array comparative genomic hybridization. Cancer Genet 2011; 204: 84-95
    • (2011) Cancer Genet , vol.204 , pp. 84-95
    • Dyrso, T.1    Li, J.2    Wang, K.3    Lindebjerg, J.4    Kolvraa, S.5    Bolund, L.6    Jakobsen, A.7    Bruun-Petersen, G.8    Li, S.9    Cruger, D.G.10
  • 42
    • 4344649186 scopus 로고    scopus 로고
    • Tumor karyotype predicts clinical outcome in colorectal cancer patients
    • Bardi G, Fenger C, Johansson B, Mitelman F, Heim S: Tumor karyotype predicts clinical outcome in colorectal cancer patients. J Clin Oncol 2004; 22: 2623-2634
    • (2004) J Clin Oncol , vol.22 , pp. 2623-2634
    • Bardi, G.1    Fenger, C.2    Johansson, B.3    Mitelman, F.4    Heim, S.5
  • 43
    • 84858166365 scopus 로고    scopus 로고
    • Molecular pathways: Microsatellite instability in colorectal cancer: Prognostic, predictive, and therapeutic implications
    • Sinicrope FA, Sargent DJ: Molecular pathways: Microsatellite instability in colorectal cancer: Prognostic, predictive, and therapeutic implications. Clin Cancer Res 2012; 18: 1506-1512
    • (2012) Clin Cancer Res , vol.18 , pp. 1506-1512
    • Sinicrope, F.A.1    Sargent, D.J.2
  • 45
    • 73449091519 scopus 로고    scopus 로고
    • DNA mismatch repair deficiency in sporadic colorectal cancer and lynch syndrome
    • Poulogiannis G, Frayling IM, Arends MJ: DNA mismatch repair deficiency in sporadic colorectal cancer and lynch syndrome. Histopathology 2010; 56: 167-179
    • (2010) Histopathology , vol.56 , pp. 167-179
    • Poulogiannis, G.1    Frayling, I.M.2    Arends, M.J.3
  • 46
    • 39049167505 scopus 로고    scopus 로고
    • Slip slidin' away: A duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
    • Royrvik EC, Ahlquist T, Rognes T, Lothe RA: Slip slidin' away: A duodecennial review of targeted genes in mismatch repair deficient colorectal cancer. Crit Rev Oncog 2007; 13: 229-257
    • (2007) Crit Rev Oncog , vol.13 , pp. 229-257
    • Royrvik, E.C.1    Ahlquist, T.2    Rognes, T.3    Lothe, R.A.4
  • 47
    • 77956067587 scopus 로고    scopus 로고
    • Lymph node harvest in colon cancer: Influence of microsatellite instability and proximal tumor location
    • Soreide K, Nedrebo BS, Soreide JA, Slewa A, Korner H: Lymph node harvest in colon cancer: Influence of microsatellite instability and proximal tumor location. World J Surg 2009; 33: 2695-2703
    • (2009) World J Surg , vol.33 , pp. 2695-2703
    • Soreide, K.1    Nedrebo, B.S.2    Soreide, J.A.3    Slewa, A.4    Korner, H.5
  • 48
    • 59449091416 scopus 로고    scopus 로고
    • Microsatellite instability and DNA ploidy in colorectal cancer: Potential implications for patients undergoing systematic surveillance after resection
    • Soreide K, Slewa A, Stokkeland PJ, van Diermen B, Janssen EA, Soreide JA, Baak JP, Korner H: Microsatellite instability and DNA ploidy in colorectal cancer: Potential implications for patients undergoing systematic surveillance after resection. Cancer 2009; 115: 271-282
    • (2009) Cancer , vol.115 , pp. 271-282
    • Soreide, K.1    Slewa, A.2    Stokkeland, P.J.3    Van Diermen, B.4    Janssen, E.A.5    Soreide, J.A.6    Baak, J.P.7    Korner, H.8
  • 49
    • 77957197346 scopus 로고    scopus 로고
    • Microsatellite instability as a marker of prognosis and response to therapy: A meta-Analysis of colorectal cancer survival data
    • Guastadisegni C, Colafranceschi M, Ottini L, Dogliotti E: Microsatellite instability as a marker of prognosis and response to therapy: A meta-Analysis of colorectal cancer survival data. Eur J Cancer 2010; 46: 2788-2798
    • (2010) Eur J Cancer , vol.46 , pp. 2788-2798
    • Guastadisegni, C.1    Colafranceschi, M.2    Ottini, L.3    Dogliotti, E.4
  • 53
    • 67650083194 scopus 로고    scopus 로고
    • Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-Analysis
    • Des Guetz G, Uzzan B, Nicolas P, Schischmanoff O, Perret GY, Morere JF: Microsatellite instability does not predict the efficacy of chemotherapy in metastatic colorectal cancer. A systematic review and meta-Analysis. Anticancer Res 2009; 29: 1615-1620
    • (2009) Anticancer Res , vol.29 , pp. 1615-1620
    • Des Guetz, G.1    Uzzan, B.2    Nicolas, P.3    Schischmanoff, O.4    Perret, G.Y.5    Morere, J.F.6
  • 54
    • 66949113291 scopus 로고    scopus 로고
    • Does microsatellite instability predict the efficacy of adjuvant chemotherapy in colorectal cancer? A systematic review with meta-Analysis
    • Des Guetz G, Schischmanoff O, Nicolas P, Perret GY, Morere JF, Uzzan B: Does microsatellite instability predict the efficacy of adjuvant chemotherapy in colorectal cancer? A systematic review with meta-Analysis. Eur J Cancer 2009; 45: 1890-1896
    • (2009) Eur J Cancer , vol.45 , pp. 1890-1896
    • Des Guetz, G.1    Schischmanoff, O.2    Nicolas, P.3    Perret, G.Y.4    Morere, J.F.5    Uzzan, B.6
  • 55
    • 77949270273 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer-The stable evidence
    • Vilar E, Gruber SB: Microsatellite instability in colorectal cancer-The stable evidence. Nat Rev Clin Oncol 2010; 7: 153-162
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 153-162
    • Vilar, E.1    Gruber, S.B.2
  • 56
    • 44449100509 scopus 로고    scopus 로고
    • Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia
    • Kim YS, Deng GR: Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia. Gut Liver 2007; 1: 1-11
    • (2007) Gut Liver , vol.1 , pp. 1-11
    • Kim, Y.S.1    Deng, G.R.2
  • 57
    • 77956103532 scopus 로고    scopus 로고
    • A review of the most promising biomarkers in colorectal cancer: One step closer to targeted therapy
    • Deschoolmeester V, Baay M, Specenier P, Lardon F, Vermorken JB: A review of the most promising biomarkers in colorectal cancer: One step closer to targeted therapy. Oncologist 2010; 15: 699-731
    • (2010) Oncologist , vol.15 , pp. 699-731
    • Deschoolmeester, V.1    Baay, M.2    Specenier, P.3    Lardon, F.4    Vermorken, J.B.5
  • 58
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass JR: Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007; 50: 113-130
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 59
    • 84868144489 scopus 로고    scopus 로고
    • Stratification and prognostic relevance of Jass's molecular classification of colorectal cancer
    • Zlobec I, Bihl MP, Foerster A, Rufle A, Terracciano L, Lugli A: Stratification and prognostic relevance of Jass's molecular classification of colorectal cancer. Front Oncol 2012; 2: 7.
    • (2012) Front Oncol , vol.2 , pp. 7
    • Zlobec, I.1    Bihl, M.P.2    Foerster, A.3    Rufle, A.4    Terracciano, L.5    Lugli, A.6
  • 61
    • 79958806016 scopus 로고    scopus 로고
    • Four molecular subtypes of colorectal cancer and their precursor lesions
    • Kang GH: Four molecular subtypes of colorectal cancer and their precursor lesions. Arch Pathol Lab Med 2011; 135: 698-703
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 698-703
    • Kang, G.H.1
  • 62
    • 84864613664 scopus 로고    scopus 로고
    • Interdisciplinary education to integrate pathology and epidemiology: Towards molecular and populationlevel health science
    • Ogino S, King EE, Beck AH, Sherman ME, Milner DA, Giovannucci E: Interdisciplinary education to integrate pathology and epidemiology: Towards molecular and populationlevel health science. Am J Epidemiol 2012; 176: 659-667
    • (2012) Am J Epidemiol , vol.176 , pp. 659-667
    • Ogino, S.1    King, E.E.2    Beck, A.H.3    Sherman, M.E.4    Milner, D.A.5    Giovannucci, E.6
  • 63
    • 84864579906 scopus 로고    scopus 로고
    • How many molecular subtypes? Implications of the unique tumor principle in personalized medicine
    • Ogino S, Fuchs CS, Giovannucci E: How many molecular subtypes? Implications of the unique tumor principle in personalized medicine. Expert Rev Mol Diagn 2012; 12: 621- 628
    • (2012) Expert Rev Mol Diagn , vol.12 , pp. 621-628
    • Ogino, S.1    Fuchs, C.S.2    Giovannucci, E.3
  • 64
    • 77949435827 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
    • Bardelli A, Siena S: Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer. J Clin Oncol 2010; 28: 1254- 1261
    • (2010) J Clin Oncol , vol.28 , pp. 1254-1261
    • Bardelli, A.1    Siena, S.2
  • 65
    • 84874180366 scopus 로고    scopus 로고
    • EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/ AKT pathways in colorectal cancer-implications for targeted therapy
    • Berg M, Soreide K: EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/ AKT pathways in colorectal cancer-implications for targeted therapy. Discov Med 2012; 14: 207-214
    • (2012) Discov Med , vol.14 , pp. 207-214
    • Berg, M.1    Soreide, K.2
  • 69
    • 0034845958 scopus 로고    scopus 로고
    • PKB/AKT: A key mediator of cell proliferation, survival and insulin responses?
    • Lawlor MA, Alessi DR: PKB/AKT: A key mediator of cell proliferation, survival and insulin responses? J Cell Sci 2001; 114: 2903-2910
    • (2001) J Cell Sci , vol.114 , pp. 2903-2910
    • Lawlor, M.A.1    Alessi, D.R.2
  • 71
    • 27844526600 scopus 로고    scopus 로고
    • Akt-dependent transformation: There is more to growth than just surviving
    • Plas DR, Thompson CB: Akt-dependent transformation: There is more to growth than just surviving. Oncogene 2005; 24: 7435-7442
    • (2005) Oncogene , vol.24 , pp. 7435-7442
    • Plas, D.R.1    Thompson, C.B.2
  • 72
    • 19044390942 scopus 로고    scopus 로고
    • The role of prostaglandins and other eicosanoids in the gastrointestinal tract
    • Wang D, Mann JR, DuBois RN: The role of prostaglandins and other eicosanoids in the gastrointestinal tract. Gastroenterology 2005; 128: 1445-1461
    • (2005) Gastroenterology , vol.128 , pp. 1445-1461
    • Wang, D.1    Mann, J.R.2    DuBois, R.N.3
  • 73
    • 0030894288 scopus 로고    scopus 로고
    • Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer
    • Levy GN: Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB J 1997; 11: 234-247
    • (1997) FASEB J , vol.11 , pp. 234-247
    • Levy, G.N.1
  • 74
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM: Cyclooxygenases: Structural, cellular, and molecular biology. Annu Rev Biochem 2000; 69: 145- 182
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 75
    • 0029924110 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide synthase Why two isoforms?
    • Williams CS, DuBois RN: Prostaglandin endoperoxide synthase: Why two isoforms? Am J Physiol 1996; 270:G393-G400
    • (1996) Am J Physiol , vol.270
    • Williams, C.S.1    DuBois, R.N.2
  • 76
    • 0028261042 scopus 로고
    • Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E 2
    • Pugh S, Thomas GA: Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E 2 . Gut 1994; 35: 675-678
    • (1994) Gut , vol.35 , pp. 675-678
    • Pugh, S.1    Thomas, G.A.2
  • 77
    • 0027371123 scopus 로고
    • Altered eicosanoid levels in human colon cancer
    • Rigas B, Goldman IS, Levine L: Altered eicosanoid levels in human colon cancer. J Lab Clin Med 1993; 122: 518-523
    • (1993) J Lab Clin Med , vol.122 , pp. 518-523
    • Rigas, B.1    Goldman, I.S.2    Levine, L.3
  • 78
    • 33644782816 scopus 로고    scopus 로고
    • Identification of a new class of prostaglandin transporter inhibitors and characterization of their biological effects on prostaglandin E 2 transport
    • Chi Y, Khersonsky SM, Chang YT, Schuster VL: Identification of a new class of prostaglandin transporter inhibitors and characterization of their biological effects on prostaglandin E 2 transport. J Pharmacol Exp Ther 2006; 316: 1346-1350
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 1346-1350
    • Chi, Y.1    Khersonsky, S.M.2    Chang, Y.T.3    Schuster, V.L.4
  • 80
    • 1242314857 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in colorectal cancer
    • Sinicrope FA, Gill S: Role of cyclooxygenase-2 in colorectal cancer. Cancer Metastasis Rev 2004; 23: 63-75
    • (2004) Cancer Metastasis Rev , vol.23 , pp. 63-75
    • Sinicrope, F.A.1    Gill, S.2
  • 82
    • 23844502011 scopus 로고    scopus 로고
    • Is COX-2 a 'collateral' target in cancer prevention?
    • Kashfi K, Rigas B: Is COX-2 a 'collateral' target in cancer prevention? Biochem Soc Trans 2005; 33: 724-727
    • (2005) Biochem Soc Trans , vol.33 , pp. 724-727
    • Kashfi, K.1    Rigas, B.2
  • 86
    • 0033913275 scopus 로고    scopus 로고
    • Translational studies on COX-2 inhibitors in the prevention and treatment of colon cancer
    • Gupta RA, DuBois RN: Translational studies on COX-2 inhibitors in the prevention and treatment of colon cancer. Ann NY Acad Sci 2000; 910: 196-204
    • (2000) Ann NY Acad Sci , vol.910 , pp. 196-204
    • Gupta, R.A.1    DuBois, R.N.2
  • 88
    • 34248231930 scopus 로고    scopus 로고
    • Can aspirin prevent colorectal cancer?
    • Chan AT: Can aspirin prevent colorectal cancer? Lancet 2007; 369: 1577-1578
    • (2007) Lancet , vol.369 , pp. 1577-1578
    • Chan, A.T.1
  • 89
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials
    • Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, Mehta Z: Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials. Lancet 2012; 379: 1591-1601
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3    Belch, J.F.4    Meade, T.W.5    Mehta, Z.6
  • 90
    • 56249120580 scopus 로고    scopus 로고
    • Proline oxidase, a p53-induced gene, targets COX-2/PGE 2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
    • Liu Y, Borchert GL, Surazynski A, Phang JM: Proline oxidase, a p53-induced gene, targets COX-2/PGE 2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers. Oncogene 2008; 27: 6729-6737
    • (2008) Oncogene , vol.27 , pp. 6729-6737
    • Liu, Y.1    Borchert, G.L.2    Surazynski, A.3    Phang, J.M.4
  • 92
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • Wang D, Dubois R: Prostaglandins and cancer. Gut 2006; 55: 115-122
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    Dubois, R.2
  • 93
    • 79952441106 scopus 로고    scopus 로고
    • Prevention: Will an aspirin a day keep the colorectal cancer away?
    • Berg M, Soreide K: Prevention: Will an aspirin a day keep the colorectal cancer away? Nat Rev Clin Oncol 2011; 8: 130-131
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 130-131
    • Berg, M.1    Soreide, K.2
  • 94
    • 84872853140 scopus 로고    scopus 로고
    • Global estimates of cancer prevalence for 27 sites in the adult population in 2008
    • Bray F, Ren JS, Masuyer E, Ferlay J: Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer 2013; 132: 1133-1145
    • (2013) Int J Cancer , vol.132 , pp. 1133-1145
    • Bray, F.1    Ren, J.S.2    Masuyer, E.3    Ferlay, J.4
  • 95
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: A cancer hallmark even Warburg did not anticipate
    • Ward PS, Thompson CB: Metabolic reprogramming: A cancer hallmark even Warburg did not anticipate. Cancer Cell 2012; 21: 297- 308
    • (2012) Cancer Cell , vol.21 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 96
    • 78649391422 scopus 로고    scopus 로고
    • Cellular metabolic stress: Considering how cells respond to nutrient excess
    • Wellen KE, Thompson CB: Cellular metabolic stress: Considering how cells respond to nutrient excess. Mol Cell 2010; 40: 323-332
    • (2010) Mol Cell , vol.40 , pp. 323-332
    • Wellen, K.E.1    Thompson, C.B.2
  • 97
    • 70450231612 scopus 로고    scopus 로고
    • Energetics, epigenetics, mitochondrial genetics
    • Wallace DC, Fan W: Energetics, epigenetics, mitochondrial genetics. Mitochondrion 2010; 10: 12-31
    • (2010) Mitochondrion , vol.10 , pp. 12-31
    • Wallace, D.C.1    Fan, W.2
  • 98
  • 100
    • 84868635149 scopus 로고    scopus 로고
    • Searching for consistently reported up- and down-regulated biomarkers in colorectal cancer: A systematic review of proteomic studies
    • Ma Y, Zhang P, Wang F, Qin H: Searching for consistently reported up- and down-regulated biomarkers in colorectal cancer: A systematic review of proteomic studies. Mol Biol Rep 2012; 39: 8483-8490
    • (2012) Mol Biol Rep , vol.39 , pp. 8483-8490
    • Ma, Y.1    Zhang, P.2    Wang, F.3    Qin, H.4
  • 101
    • 80052242132 scopus 로고    scopus 로고
    • Targeting cancer metabolism: A therapeutic window opens
    • Vander Heiden MG: Targeting cancer metabolism: A therapeutic window opens. Nat Rev Drug Discov 2011; 10: 671-684
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 671-684
    • Vander Heiden, M.G.1
  • 102
  • 106
    • 84870341638 scopus 로고    scopus 로고
    • Why your new cancer biomarker
    • may never work: Recurrent patterns and remarkable diversity in biomarker failures
    • Kern SE: Why your new cancer biomarker may never work: Recurrent patterns and remarkable diversity in biomarker failures. Cancer Res 2012; 72: 6097-6101
    • (2012) Cancer Res , vol.72 , pp. 6097-6101
    • Kern, S.E.1
  • 107
    • 33846620129 scopus 로고    scopus 로고
    • Diagnostic accuracy of serum-carcinoembryonic antigen in recurrent colorectal cancer: A receiver-operating characteristic curve analysis
    • Korner H, Soreide K, Stokkeland PJ, Soreide JA: Diagnostic accuracy of serum-carcinoembryonic antigen in recurrent colorectal cancer: A receiver-operating characteristic curve analysis. Ann Surg Oncol 2007; 14: 417-423
    • (2007) Ann Surg Oncol , vol.14 , pp. 417-423
    • Korner, H.1    Soreide, K.2    Stokkeland, P.J.3    Soreide, J.A.4
  • 108
    • 60549088708 scopus 로고    scopus 로고
    • Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer
    • Tan E, Gouvas N, Nicholls RJ, Ziprin P, Xynos E, Tekkis PP: Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer. Surg Oncol 2009; 18: 15-24
    • (2009) Surg Oncol , vol.18 , pp. 15-24
    • Tan, E.1    Gouvas, N.2    Nicholls, R.J.3    Ziprin, P.4    Xynos, E.5    Tekkis, P.P.6
  • 109
    • 0035660907 scopus 로고    scopus 로고
    • Carcinoembryonic antigen as an independent prognostic factor of recurrence and survival in patients resected for colorectal liver metastases: A systematic review
    • Watine J, Miedouge M, Friedberg B: Carcinoembryonic antigen as an independent prognostic factor of recurrence and survival in patients resected for colorectal liver metastases: A systematic review. Dis Colon Rectum 2001; 44: 1791-1799
    • (2001) Dis Colon Rectum , vol.44 , pp. 1791-1799
    • Watine, J.1    Miedouge, M.2    Friedberg, B.3
  • 110
    • 79952191257 scopus 로고    scopus 로고
    • Prognostic role of carcinoembryonic antigen is influenced by microsatellite instability genotype and stage in locally advanced colorectal cancers
    • Soreide K, Soreide JA, Korner H: Prognostic role of carcinoembryonic antigen is influenced by microsatellite instability genotype and stage in locally advanced colorectal cancers. World J Surg 2011; 35: 888-894
    • (2011) World J Surg , vol.35 , pp. 888-894
    • Soreide, K.1    Soreide, J.A.2    Korner, H.3
  • 116
    • 84867046113 scopus 로고    scopus 로고
    • A seven-gene signature aggregates a subgroup of stage II colon cancers with stage III
    • Laibe S, Lagarde A, Ferrari A, Monges G, Birnbaum D, Olschwang S: A seven-gene signature aggregates a subgroup of stage II colon cancers with stage III. OMICS 2012; 16: 560-565
    • (2012) OMICS , vol.16 , pp. 560-565
    • Laibe, S.1    Lagarde, A.2    Ferrari, A.3    Monges, G.4    Birnbaum, D.5    Olschwang, S.6
  • 117
    • 84863349895 scopus 로고    scopus 로고
    • High accordance in prognosis prediction of colorectal cancer across independent datasets by multi-gene module expression profiles
    • Li W, Wang R, Yan Z, Bai L, Sun Z: High accordance in prognosis prediction of colorectal cancer across independent datasets by multi-gene module expression profiles. PloS One 2012; 7:e33653
    • (2012) PloS One , vol.7
    • Li, W.1    Wang, R.2    Yan, Z.3    Bai, L.4    Sun, Z.5
  • 119
    • 84864190709 scopus 로고    scopus 로고
    • A network- based gene expression signature informs prognosis and treatment for colorectal cancer patients
    • Shi M, Beauchamp RD, Zhang B: A network- based gene expression signature informs prognosis and treatment for colorectal cancer patients. PloS One 2012; 7:e41292
    • (2012) PloS One , vol.7
    • Shi, M.1    Beauchamp, R.D.2    Zhang, B.3
  • 122
    • 84871190036 scopus 로고    scopus 로고
    • A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency
    • (E-pub ahead of print
    • Tian S, Roepman P, Popovici V, Michaut M, Majewski I, Salazar R, et al: A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency. J Pathol 2012 (E-pub ahead of print
    • (2012) J Pathol
    • Tian, S.1    Roepman, P.2    Popovici, V.3    Michaut, M.4    Majewski, I.5    Salazar, R.6
  • 123
    • 84860184315 scopus 로고    scopus 로고
    • Characterization of gene-environment interactions for colorectal cancer susceptibility loci
    • Hutter CM, Chang-Claude J, Slattery ML, Pflugeisen BM, Lin Y, Duggan D, et al: Characterization of gene-environment interactions for colorectal cancer susceptibility loci. Cancer Res 2012; 72: 2036-2044
    • (2012) Cancer Res , vol.72 , pp. 2036-2044
    • Hutter, C.M.1    Chang-Claude, J.2    Slattery, M.L.3    Pflugeisen, B.M.4    Lin, Y.5    Duggan, D.6
  • 125
    • 78751630983 scopus 로고    scopus 로고
    • Diagnostic accuracy and receiver-operating characteristics curve analysis in surgical research and decision making
    • Soreide K, Korner H, Soreide JA: Diagnostic accuracy and receiver-operating characteristics curve analysis in surgical research and decision making. Ann Surg 2011; 253: 27-34
    • (2011) Ann Surg , vol.253 , pp. 27-34
    • Soreide, K.1    Korner, H.2    Soreide, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.