Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers

Oncogene

Volumn 27, Issue 53, 2008, Pages 6729-6737

  Liu, Y ^a   Borchert, G L ^a   Surazynski, A ^b   Phang, J M ^b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Colorectal cancer; COX 2; Proline oxidase; Signaling cross talk; Tumor suppressor

Indexed keywords

BETA CATENIN; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; PROLINE DEHYDROGENASE; PROSTAGLANDIN E2; TETRACYCLINE; WNT PROTEIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; COLORECTAL CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; BETA CATENIN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; DINOPROSTONE; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PROLINE; PROLINE OXIDASE; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; WNT PROTEINS;

EID: 56249120580     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.322     Document Type: Article

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