메뉴 건너뛰기




Volumn 204, Issue 2, 2011, Pages 84-95

Identification of chromosome aberrations in sporadic microsatellite stable and unstable colorectal cancers using array comparative genomic hybridization

Author keywords

Array CGH; Chromosome instability; Colorectal cancer; Microsatellite instability; Microsatellite stability

Indexed keywords

PROTEIN P53; MICROSATELLITE DNA;

EID: 79958255986     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2010.08.019     Document Type: Article
Times cited : (17)

References (96)
  • 1
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319: 525-532.
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 2
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 3
    • 15844390729 scopus 로고    scopus 로고
    • Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
    • Thiagalingam S, Lengauer C, Leach FS, et al. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat Genet 1996;13:343-346.
    • (1996) Nat Genet , vol.13 , pp. 343-346
    • Thiagalingam, S.1    Lengauer, C.2    Leach, F.S.3
  • 4
    • 0023223410 scopus 로고
    • Localization of the gene for familial adenomatous polyposis on chromosome 5
    • Bodmer WF, Bailey CJ, Bodmer J, et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987;328:614-616.
    • (1987) Nature , vol.328 , pp. 614-616
    • Bodmer, W.F.1    Bailey, C.J.2    Bodmer, J.3
  • 5
    • 0025056930 scopus 로고
    • Identification of a chromosome 18q gene that is altered in colorectal cancers
    • Fearon ER, Cho KR, Nigro JM, et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (NY) 1990;247:49-56.
    • (1990) Science (NY) , vol.247 , pp. 49-56
    • Fearon, E.R.1    Cho, K.R.2    Nigro, J.M.3
  • 6
    • 0024536654 scopus 로고
    • Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
    • Baker SJ, Fearon ER, Nigro JM, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (NY) 1989;244:217-221.
    • (1989) Science (NY) , vol.244 , pp. 217-221
    • Baker, S.J.1    Fearon, E.R.2    Nigro, J.M.3
  • 7
    • 0020677360 scopus 로고
    • Characterization of a human colon/lung carcinoma oncogene
    • McCoy MS, Toole JJ, Cunningham JM, et al. Characterization of a human colon/lung carcinoma oncogene. Nature 1983;302:79-81.
    • (1983) Nature , vol.302 , pp. 79-81
    • McCoy, M.S.1    Toole, J.J.2    Cunningham, J.M.3
  • 8
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998;396:643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 9
    • 0036727291 scopus 로고    scopus 로고
    • Emerging concepts in colorectal neoplasia
    • Jass JR, Whitehall VL, Young J, et al. Emerging concepts in colorectal neoplasia. Gastroenterology 2002;123:862-876.
    • (2002) Gastroenterology , vol.123 , pp. 862-876
    • Jass, J.R.1    Whitehall, V.L.2    Young, J.3
  • 10
    • 0028859671 scopus 로고
    • Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
    • Liu B, Nicolaides NC, Markowitz S, et al. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat Genet 1995;9:48-55.
    • (1995) Nat Genet , vol.9 , pp. 48-55
    • Liu, B.1    Nicolaides, N.C.2    Markowitz, S.3
  • 11
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instability in colorectal cancers. Nature 1997;386:623-627.
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 12
    • 12444261784 scopus 로고    scopus 로고
    • Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma
    • Jones AM, Douglas EJ, Halford SE, et al. Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma. Oncogene 2005; 24:118-129.
    • (2005) Oncogene , vol.24 , pp. 118-129
    • Jones, A.M.1    Douglas, E.J.2    Halford, S.E.3
  • 13
    • 0035150962 scopus 로고    scopus 로고
    • Microsatellitestable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer
    • Hawkins NJ, Tomlinson I, Meagher A, et al. Microsatellitestable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer. Br J Cancer 2001;84: 232-236.
    • (2001) Br J Cancer , vol.84 , pp. 232-236
    • Hawkins, N.J.1    Tomlinson, I.2    Meagher, A.3
  • 14
    • 0037732863 scopus 로고    scopus 로고
    • Near-diploid and neartriploid human sporadic colorectal adenocarcinomas differ for KRAS2 and TP53 mutational status
    • Giaretti W, Venesio T, Sciutto A, et al. Near-diploid and neartriploid human sporadic colorectal adenocarcinomas differ for KRAS2 and TP53 mutational status. Genes Chromosomes Cancer 2003;37:207-213.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 207-213
    • Giaretti, W.1    Venesio, T.2    Sciutto, A.3
  • 15
    • 1242292420 scopus 로고    scopus 로고
    • Genomic instability and colon cancer
    • Grady WM. Genomic instability and colon cancer. Cancer metastasis reviews 2004;23:11-27.
    • (2004) Cancer metastasis reviews , vol.23 , pp. 11-27
    • Grady, W.M.1
  • 16
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990;345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 17
    • 0017166058 scopus 로고
    • Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
    • Benn PA. Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am J Human Genet 1976;28:465-473.
    • (1976) Am J Human Genet , vol.28 , pp. 465-473
    • Benn, P.A.1
  • 18
    • 0034597794 scopus 로고    scopus 로고
    • Telomere states and cell fates
    • Blackburn EH. Telomere states and cell fates. Nature 2000;408: 53-56.
    • (2000) Nature , vol.408 , pp. 53-56
    • Blackburn, E.H.1
  • 19
    • 0025143252 scopus 로고
    • Telomere reduction in human colorectal carcinoma and with ageing
    • Hastie ND, Dempster M, Dunlop MG, et al. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990; 346:866-868.
    • (1990) Nature , vol.346 , pp. 866-868
    • Hastie, N.D.1    Dempster, M.2    Dunlop, M.G.3
  • 21
    • 0027235369 scopus 로고
    • Cancer. A death in the life of p53
    • Lane DP. Cancer. A death in the life of p53. Nature 1993;362: 786-787.
    • (1993) Nature , vol.362 , pp. 786-787
    • Lane, D.P.1
  • 22
    • 0028569767 scopus 로고
    • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
    • Smith ML, Chen IT, Zhan Q, et al. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science (NY) 1994;266:1376-1380.
    • (1994) Science (NY) , vol.266 , pp. 1376-1380
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3
  • 23
    • 3142691130 scopus 로고    scopus 로고
    • Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas
    • Douglas EJ, Fiegler H, Rowan A, et al. Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Res 2004;64:4817-4825.
    • (2004) Cancer Res , vol.64 , pp. 4817-4825
    • Douglas, E.J.1    Fiegler, H.2    Rowan, A.3
  • 24
    • 1842475973 scopus 로고    scopus 로고
    • High-resolution analysis of DNA copy number alterations in colorectal cancer by arraybased comparative genomic hybridization
    • Nakao K, Mehta KR, Fridlyand J, et al. High-resolution analysis of DNA copy number alterations in colorectal cancer by arraybased comparative genomic hybridization. Carcinogenesis 2004;25:1345-1357.
    • (2004) Carcinogenesis , vol.25 , pp. 1345-1357
    • Nakao, K.1    Mehta, K.R.2    Fridlyand, J.3
  • 25
    • 33644860129 scopus 로고    scopus 로고
    • Genome-wide differences between microsatellite stable and unstable colorectal tumors
    • Camps J, Armengol G, del Rey J, et al. Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis 2006;27:419-428.
    • (2006) Carcinogenesis , vol.27 , pp. 419-428
    • Camps, J.1    Armengol, G.2    del Rey, J.3
  • 26
    • 33847148511 scopus 로고    scopus 로고
    • Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas
    • Lassmann S, Weis R, Makowiec F, et al. Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas. J Mol Med 2007;85:293-304.
    • (2007) J Mol Med , vol.85 , pp. 293-304
    • Lassmann, S.1    Weis, R.2    Makowiec, F.3
  • 27
    • 2342475733 scopus 로고    scopus 로고
    • BAC microarraybased comparative genomic hybridization
    • Snijders AM, Segraves R, Blackwood S, et al. BAC microarraybased comparative genomic hybridization. Methods Mol Biol 2004;256:39-56.
    • (2004) Methods Mol Biol , vol.256 , pp. 39-56
    • Snijders, A.M.1    Segraves, R.2    Blackwood, S.3
  • 29
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • Olshen AB, Venkatraman ES, Lucito R, et al. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 2004;5:557-572.
    • (2004) Biostatistics , vol.5 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3
  • 30
    • 27944455289 scopus 로고    scopus 로고
    • A comparison study: applying segmentation to array CGH data for downstream analyses
    • Willenbrock H, Fridlyand J. A comparison study: applying segmentation to array CGH data for downstream analyses. Bioinformatics 2005;21:4084-4091.
    • (2005) Bioinformatics , vol.21 , pp. 4084-4091
    • Willenbrock, H.1    Fridlyand, J.2
  • 31
    • 33745599876 scopus 로고    scopus 로고
    • Laser microdissection and microsatellite analysis of colorectal adenocarcinomas
    • Jensen LH, Cruger DG, Lindebjerg J, et al. Laser microdissection and microsatellite analysis of colorectal adenocarcinomas. Anticancer research 2006;26:2069-2074.
    • (2006) Anticancer research , vol.26 , pp. 2069-2074
    • Jensen, L.H.1    Cruger, D.G.2    Lindebjerg, J.3
  • 32
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on microsatellite instability for cancer detection and familial predisposition: development of internationalcriteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on microsatellite instability for cancer detection and familial predisposition: development of internationalcriteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-5257.
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3
  • 33
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993;363:558-561.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3
  • 34
    • 0036817451 scopus 로고    scopus 로고
    • Pathogenesis of colorectal cancer
    • Jass JR. Pathogenesis of colorectal cancer. Surg Clin N Am 2002;82:891-904.
    • (2002) Surg Clin N Am , vol.82 , pp. 891-904
    • Jass, J.R.1
  • 35
    • 0035100615 scopus 로고    scopus 로고
    • Prognostic significance of recurrent chromosomal aberrations detected by comparative genomic hybridization in sporadic colorectal cancer
    • De Angelis PM, Stokke T, Beigi M, et al. Prognostic significance of recurrent chromosomal aberrations detected by comparative genomic hybridization in sporadic colorectal cancer. Int J Colorect Dis 2001;16:38-45.
    • (2001) Int J Colorect Dis , vol.16 , pp. 38-45
    • De Angelis, P.M.1    Stokke, T.2    Beigi, M.3
  • 36
    • 0032436224 scopus 로고    scopus 로고
    • Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation
    • Meijer GA, Hermsen MA, Baak JP, et al. Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation. J Clin Pathol 1998;51:901-909.
    • (1998) J Clin Pathol , vol.51 , pp. 901-909
    • Meijer, G.A.1    Hermsen, M.A.2    Baak, J.P.3
  • 37
    • 0029866286 scopus 로고    scopus 로고
    • Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors
    • Ried T, Knutzen R, Steinbeck R, et al. Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors. Genes Chromosomes Cancer 1996;15:234-245.
    • (1996) Genes Chromosomes Cancer , vol.15 , pp. 234-245
    • Ried, T.1    Knutzen, R.2    Steinbeck, R.3
  • 38
    • 0027240519 scopus 로고
    • Identification of the von Hippel-Lindau disease tumor suppressor gene
    • Latif F, Tory K, Gnarra J, et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science (NY) 1993; 260:1317-1320.
    • (1993) Science (NY) , vol.260 , pp. 1317-1320
    • Latif, F.1    Tory, K.2    Gnarra, J.3
  • 39
    • 0028788184 scopus 로고
    • Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas
    • Eng C, Crossey PA, Mulligan LM, et al. Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas. J Med Genet 1995;32:934-937.
    • (1995) J Med Genet , vol.32 , pp. 934-937
    • Eng, C.1    Crossey, P.A.2    Mulligan, L.M.3
  • 40
    • 0029061518 scopus 로고
    • Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene
    • Kuzmin I, Duh FM, Latif F, et al. Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene. Oncogene 1995;10:2185-2194.
    • (1995) Oncogene , vol.10 , pp. 2185-2194
    • Kuzmin, I.1    Duh, F.M.2    Latif, F.3
  • 41
    • 0028857959 scopus 로고
    • Microcell mediated chromosome transfer maps the Fanconi anaemia group D gene to chromosome 3p
    • Whitney M, Thayer M, Reifsteck C, et al. Microcell mediated chromosome transfer maps the Fanconi anaemia group D gene to chromosome 3p. Nat Genet 1995;11:341-343.
    • (1995) Nat Genet , vol.11 , pp. 341-343
    • Whitney, M.1    Thayer, M.2    Reifsteck, C.3
  • 42
    • 7344247650 scopus 로고    scopus 로고
    • Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene
    • Sekido Y, Ahmadian M, Wistuba II, et al. Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene. Oncogene 1998;16: 3151-3157.
    • (1998) Oncogene , vol.16 , pp. 3151-3157
    • Sekido, Y.1    Ahmadian, M.2    Wistuba, I.I.3
  • 43
    • 7844226649 scopus 로고    scopus 로고
    • Homozygous deletions at 3p12 in breast and lung cancer
    • Sundaresan V, Chung G, Heppell-Parton A, et al. Homozygous deletions at 3p12 in breast and lung cancer. Oncogene 1998;17: 1723-1729.
    • (1998) Oncogene , vol.17 , pp. 1723-1729
    • Sundaresan, V.1    Chung, G.2    Heppell-Parton, A.3
  • 44
    • 36148946432 scopus 로고    scopus 로고
    • Evaluation of the 3p21.3 tumoursuppressor gene cluster
    • Hesson LB, Cooper WN, Latif F. Evaluation of the 3p21.3 tumoursuppressor gene cluster. Oncogene 2007;26:7283-7301.
    • (2007) Oncogene , vol.26 , pp. 7283-7301
    • Hesson, L.B.1    Cooper, W.N.2    Latif, F.3
  • 45
    • 0034327412 scopus 로고    scopus 로고
    • The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium
    • Lerman MI, Minna JD. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. Cancer Res 2000;60:6116-6133.
    • (2000) Cancer Res , vol.60 , pp. 6116-6133
    • Lerman, M.I.1    Minna, J.D.2
  • 46
    • 0026531915 scopus 로고
    • A gene from human chromosome region 3p21 with reduced expression in small cell lung cancer
    • Carritt B, Kok K, van den Berg A, et al. A gene from human chromosome region 3p21 with reduced expression in small cell lung cancer. Cancer Res 1992;52:1536-1541.
    • (1992) Cancer Res , vol.52 , pp. 1536-1541
    • Carritt, B.1    Kok, K.2    van den Berg, A.3
  • 47
    • 0027180655 scopus 로고
    • A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme
    • Kok K, Hofstra R, Pilz A, et al. A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme. Proc Natl Acad Sci USA 1993;90:6071-6075.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6071-6075
    • Kok, K.1    Hofstra, R.2    Pilz, A.3
  • 48
    • 0347667234 scopus 로고    scopus 로고
    • TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation
    • Lee SY, Lee SY, Choi Y. TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation. J Exp Med 1997;185:1275-1285.
    • (1997) J Exp Med , vol.185 , pp. 1275-1285
    • Lee, S.Y.1    Lee, S.Y.2    Choi, Y.3
  • 49
    • 0032438240 scopus 로고    scopus 로고
    • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint
    • Bao S, Shen X, Shen K, et al. The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. Cell Growth Differ 1998;9:961-967.
    • (1998) Cell Growth Differ , vol.9 , pp. 961-967
    • Bao, S.1    Shen, X.2    Shen, K.3
  • 50
    • 0032540927 scopus 로고    scopus 로고
    • Van de Weyer I, Laus MC, et al
    • Parker AE, Van de Weyer I, Laus MC, et al. Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene. J Biol Chem 1998;273:18340-18346.
    • (1998) J Biol Chem , vol.273 , pp. 18340-18346
    • Parker, A.E.1
  • 51
    • 0033135471 scopus 로고    scopus 로고
    • HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma
    • Bao S, Chang MS, Auclair D, et al. HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma. Cancer Res 1999; 59:2023-2028.
    • (1999) Cancer Res , vol.59 , pp. 2023-2028
    • Bao, S.1    Chang, M.S.2    Auclair, D.3
  • 52
    • 0032842429 scopus 로고    scopus 로고
    • Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma
    • von Deimling F, Scharf JM, Liehr T, et al. Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma. Human Genet 1999;105:17-27.
    • (1999) Human Genet , vol.105 , pp. 17-27
    • von Deimling, F.1    Scharf, J.M.2    Liehr, T.3
  • 53
    • 0035886873 scopus 로고    scopus 로고
    • Human Rad17 is phosphorylated upon DNA damage and also overexpressed in primary non-small cell lung cancer tissues
    • Wang X, Wang L, Callister MD, et al. Human Rad17 is phosphorylated upon DNA damage and also overexpressed in primary non-small cell lung cancer tissues. Cancer Res 2001;61: 7417-7421.
    • (2001) Cancer Res , vol.61 , pp. 7417-7421
    • Wang, X.1    Wang, L.2    Callister, M.D.3
  • 54
    • 38549157617 scopus 로고    scopus 로고
    • Downregulation of RAD17 in head and neck cancer
    • Zhao M, Begum S, Ha PK, et al. Downregulation of RAD17 in head and neck cancer. Head Neck 2008;30:35-42.
    • (2008) Head Neck , vol.30 , pp. 35-42
    • Zhao, M.1    Begum, S.2    Ha, P.K.3
  • 55
    • 0029912970 scopus 로고    scopus 로고
    • Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
    • Ando-Akatsuka Y, Saitou M, Hirase T, et al. Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. The J Cell Biol 1996;133:43-47.
    • (1996) The J Cell Biol , vol.133 , pp. 43-47
    • Ando-Akatsuka, Y.1    Saitou, M.2    Hirase, T.3
  • 56
    • 0027744129 scopus 로고
    • Occludin: a novel integral membrane protein localizing at tight junctions
    • Furuse M, Hirase T, Itoh M, et al. Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol. 1993; 123(6 Pt 2):1777-1788.
    • (1993) J Cell Biol , vol.123 , Issue.6 PART 2 , pp. 1777-1788
    • Furuse, M.1    Hirase, T.2    Itoh, M.3
  • 57
    • 0032820577 scopus 로고    scopus 로고
    • Increased tight junctional permeability is associated with the development of colon cancer
    • Soler AP, Miller RD, Laughlin KV, et al. Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis 1999;20:1425-1431.
    • (1999) Carcinogenesis , vol.20 , pp. 1425-1431
    • Soler, A.P.1    Miller, R.D.2    Laughlin, K.V.3
  • 58
    • 0030787772 scopus 로고    scopus 로고
    • Expression of occludin, tight-junction-associated protein, in human digestive tract
    • Kimura Y, Shiozaki H, Hirao M, et al. Expression of occludin, tight-junction-associated protein, in human digestive tract. Am J Pathol 1997;151:45-54.
    • (1997) Am J Pathol , vol.151 , pp. 45-54
    • Kimura, Y.1    Shiozaki, H.2    Hirao, M.3
  • 59
    • 0036773176 scopus 로고    scopus 로고
    • Polarized distribution of carcinoembryonic antigen is associated with a tight junction molecule in human colorectal adenocarcinoma
    • Tobioka H, Isomura H, Kokai Y, et al. Polarized distribution of carcinoembryonic antigen is associated with a tight junction molecule in human colorectal adenocarcinoma. J Pathol 2002; 198:207-212.
    • (2002) J Pathol , vol.198 , pp. 207-212
    • Tobioka, H.1    Isomura, H.2    Kokai, Y.3
  • 60
    • 16444374786 scopus 로고    scopus 로고
    • Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study
    • Resnick MB, Konkin T, Routhier J, et al. Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study. Mod Pathol 2004;18:511-518.
    • (2004) Mod Pathol , vol.18 , pp. 511-518
    • Resnick, M.B.1    Konkin, T.2    Routhier, J.3
  • 61
    • 3042749705 scopus 로고    scopus 로고
    • Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation
    • Billings SD, Walsh SV, Fisher C, et al. Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation. Mod Pathol 2004;17:141-149.
    • (2004) Mod Pathol , vol.17 , pp. 141-149
    • Billings, S.D.1    Walsh, S.V.2    Fisher, C.3
  • 62
    • 4544385704 scopus 로고    scopus 로고
    • Tight junction-associated proteins (occludin, ZO-1, claudin-1, claudin-4) in squamous cell carcinoma and Bowen's disease
    • Morita K, Tsukita S, Miyachi Y. Tight junction-associated proteins (occludin, ZO-1, claudin-1, claudin-4) in squamous cell carcinoma and Bowen's disease. Br J Dermatol 2004;151: 328-334.
    • (2004) Br J Dermatol , vol.151 , pp. 328-334
    • Morita, K.1    Tsukita, S.2    Miyachi, Y.3
  • 63
    • 0034762756 scopus 로고    scopus 로고
    • Occludin expression in microvessels of neoplastic and non-neoplastic human brain
    • Papadopoulos MC, Saadoun S, Woodrow CJ, et al. Occludin expression in microvessels of neoplastic and non-neoplastic human brain. Neuropathol Appl Neurobiol 2001;27:384-395.
    • (2001) Neuropathol Appl Neurobiol , vol.27 , pp. 384-395
    • Papadopoulos, M.C.1    Saadoun, S.2    Woodrow, C.J.3
  • 64
    • 1242274549 scopus 로고    scopus 로고
    • Occludin expression decreases with the progression of human endometrial carcinoma
    • Tobioka H, Isomura H, Kokai Y, et al. Occludin expression decreases with the progression of human endometrial carcinoma. Hum Pathol 2004;35:159-164.
    • (2004) Hum Pathol , vol.35 , pp. 159-164
    • Tobioka, H.1    Isomura, H.2    Kokai, Y.3
  • 65
    • 33749484749 scopus 로고    scopus 로고
    • Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosisassociated genes
    • Osanai M, Murata M, Nishikiori N, et al. Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosisassociated genes. Cancer Res 2006;66:9125-9133.
    • (2006) Cancer Res , vol.66 , pp. 9125-9133
    • Osanai, M.1    Murata, M.2    Nishikiori, N.3
  • 66
    • 34249882821 scopus 로고    scopus 로고
    • Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells
    • Osanai M, Murata M, Nishikiori N, et al. Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells. Cancer Sci 2007;98: 1027-1034.
    • (2007) Cancer Sci , vol.98 , pp. 1027-1034
    • Osanai, M.1    Murata, M.2    Nishikiori, N.3
  • 67
    • 0033576617 scopus 로고    scopus 로고
    • Eplin, epithelial protein lost in neoplasm
    • Maul RS, Chang DD. EPLIN, epithelial protein lost in neoplasm. Oncogene 1999;18:7838-7841.
    • (1999) Oncogene , vol.18 , pp. 7838-7841
    • Maul, R.S.1    Chang, D.D.2
  • 68
    • 0037415614 scopus 로고    scopus 로고
    • EPLIN regulates actin dynamics by cross-linking and stabilizing filaments
    • Maul RS, Song Y, Amann KJ, et al. EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. J Cell Biol 2003;160:399-407.
    • (2003) J Cell Biol , vol.160 , pp. 399-407
    • Maul, R.S.1    Song, Y.2    Amann, K.J.3
  • 69
    • 0035853078 scopus 로고    scopus 로고
    • ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma
    • Su GH, Bansal R, Murphy KM, et al. ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma. Proc Natl Acad Sci USA 2001;98:3254-3257.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3254-3257
    • Su, G.H.1    Bansal, R.2    Murphy, K.M.3
  • 70
    • 0027328191 scopus 로고
    • Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity
    • ten Dijke P, Ichijo H, Franzen P, et al. Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene 1993;8:2879-2887.
    • (1993) Oncogene , vol.8 , pp. 2879-2887
    • ten Dijke, P.1    Ichijo, H.2    Franzen, P.3
  • 71
    • 0346992379 scopus 로고    scopus 로고
    • Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14
    • Pereira G, Schiebel E. Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14. Science (NY) 2003; 302:2120-2124.
    • (2003) Science (NY) , vol.302 , pp. 2120-2124
    • Pereira, G.1    Schiebel, E.2
  • 72
    • 33846031245 scopus 로고    scopus 로고
    • A mutation in separase causes genome instability and increased susceptibility to epithelial cancer
    • Shepard JL, Amatruda JF, Finkelstein D, et al. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes Dev 2007;21:55-59
    • (2007) Genes Dev , vol.21 , pp. 55-59
    • Shepard, J.L.1    Amatruda, J.F.2    Finkelstein, D.3
  • 73
    • 0033575347 scopus 로고    scopus 로고
    • Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
    • Zou H, McGarry TJ, Bernal T, et al. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science (NY) 1999;285:418-422.
    • (1999) Science (NY) , vol.285 , pp. 418-422
    • Zou, H.1    McGarry, T.J.2    Bernal, T.3
  • 74
    • 1642338831 scopus 로고    scopus 로고
    • HumanMCRS2,a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length
    • Song H, Li Y, Chen G, et al.HumanMCRS2,a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length. Biochem Biophys Res Commun 2004;316:1116-1123.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 1116-1123
    • Song, H.1    Li, Y.2    Chen, G.3
  • 75
    • 0032491539 scopus 로고    scopus 로고
    • MM-1, a novel c-Mycassociating protein that represses transcriptional activity of c-Myc
    • Mori K, Maeda Y, Kitaura H, et al. MM-1, a novel c-Mycassociating protein that represses transcriptional activity of c-Myc. J Biol Chem 1998;273:29794-29800.
    • (1998) J Biol Chem , vol.273 , pp. 29794-29800
    • Mori, K.1    Maeda, Y.2    Kitaura, H.3
  • 76
    • 0038642016 scopus 로고    scopus 로고
    • Identification and characterization of three new components of the mSin3A corepressor complex
    • Fleischer TC, Yun UJ, Ayer DE. Identification and characterization of three new components of the mSin3A corepressor complex. Mol Cell Biol 2003;23:3456-3467.
    • (2003) Mol Cell Biol , vol.23 , pp. 3456-3467
    • Fleischer, T.C.1    Yun, U.J.2    Ayer, D.E.3
  • 77
    • 0141706721 scopus 로고    scopus 로고
    • mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells
    • David G, Turner GM, Yao Y, et al. mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells. Genes Dev 2003;17:2396-2405.
    • (2003) Genes Dev , vol.17 , pp. 2396-2405
    • David, G.1    Turner, G.M.2    Yao, Y.3
  • 78
    • 40549126830 scopus 로고    scopus 로고
    • Mitotic regulation by NIMA-related kinases
    • O'Regan L, Blot J, Fry AM. Mitotic regulation by NIMA-related kinases. Cell Div 2007;2:25.
    • (2007) Cell Div , vol.2 , pp. 25
    • O'Regan, L.1    Blot, J.2    Fry, A.M.3
  • 79
    • 0032504942 scopus 로고    scopus 로고
    • Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12
    • Husmann K, Sers C, Fietze E, et al. Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12. Oncogene 1998;17:1305-1312.
    • (1998) Oncogene , vol.17 , pp. 1305-1312
    • Husmann, K.1    Sers, C.2    Fietze, E.3
  • 80
    • 0037171945 scopus 로고    scopus 로고
    • The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells
    • Sers C, Husmann K, Nazarenko I, et al. The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNgamma-induced cell death in human ovarian carcinoma cells. Oncogene 2002;21:2829-2839.
    • (2002) Oncogene , vol.21 , pp. 2829-2839
    • Sers, C.1    Husmann, K.2    Nazarenko, I.3
  • 81
    • 0024542620 scopus 로고
    • Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11
    • Nakamura Y, Larsson C, Julier C, et al. Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11. Am J Hum Genet 1989;44:751-755.
    • (1989) Am J Hum Genet , vol.44 , pp. 751-755
    • Nakamura, Y.1    Larsson, C.2    Julier, C.3
  • 82
    • 0024394627 scopus 로고
    • Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11
    • Thakker RV, Bouloux P, Wooding C, et al. Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11. N Engl J Med 1989;321:218-224.
    • (1989) N Engl J Med , vol.321 , pp. 218-224
    • Thakker, R.V.1    Bouloux, P.2    Wooding, C.3
  • 83
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science NY 1996;271:350-353.
    • (1996) Science NY , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 84
    • 0028321495 scopus 로고
    • Allelic loss of chromosome 18q and prognosis in colorectal cancer
    • Jen J, Kim H, Piantadosi S, et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N Engl J Med 1994;331: 213-221.
    • (1994) N Engl J Med , vol.331 , pp. 213-221
    • Jen, J.1    Kim, H.2    Piantadosi, S.3
  • 85
    • 0029955460 scopus 로고    scopus 로고
    • The DCC protein and prognosis in colorectal cancer
    • Shibata D, Reale MA, Lavin P, et al. The DCC protein and prognosis in colorectal cancer. N Engl J Med 1996;335: 1727-1732.
    • (1996) N Engl J Med , vol.335 , pp. 1727-1732
    • Shibata, D.1    Reale, M.A.2    Lavin, P.3
  • 86
    • 15244355514 scopus 로고    scopus 로고
    • DNA copy number changes at 8q11-24 in metastasized colorectal cancer
    • Buffart TE, Coffa J, Hermsen MA, et al. DNA copy number changes at 8q11-24 in metastasized colorectal cancer. Cell Oncol 2005;27:57-65.
    • (2005) Cell Oncol , vol.27 , pp. 57-65
    • Buffart, T.E.1    Coffa, J.2    Hermsen, M.A.3
  • 87
    • 27744552327 scopus 로고    scopus 로고
    • Involvement of cyclin D3 in liver metastasis of colorectal cancer, revealed by genome-wide copy-number analysis
    • Tanami H, Tsuda H, Okabe S, et al. Involvement of cyclin D3 in liver metastasis of colorectal cancer, revealed by genome-wide copy-number analysis. Lab Invest 2005;85:1118-1129.
    • (2005) Lab Invest , vol.85 , pp. 1118-1129
    • Tanami, H.1    Tsuda, H.2    Okabe, S.3
  • 88
    • 33845649043 scopus 로고    scopus 로고
    • Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization
    • Kim MY, Yim SH, Kwon MS, et al. Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization. Gastroenterology 2006;131:1913-1924.
    • (2006) Gastroenterology , vol.131 , pp. 1913-1924
    • Kim, M.Y.1    Yim, S.H.2    Kwon, M.S.3
  • 89
    • 0020028066 scopus 로고
    • Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line
    • Collins S, Groudine M. Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line. Nature 1982;298:679-681.
    • (1982) Nature , vol.298 , pp. 679-681
    • Collins, S.1    Groudine, M.2
  • 90
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science (NY) 1998;281: 1509-1512.
    • (1998) Science (NY) , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3
  • 91
    • 0037430255 scopus 로고    scopus 로고
    • 8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas
    • Ioannidis P, Mahaira L, Papadopoulou A, et al. 8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas. Int J Cancer 2003;104:54-59.
    • (2003) J Cancer , vol.104 , pp. 54-59
    • Ioannidis, P.1    Mahaira, L.2    Papadopoulou, A.3
  • 92
    • 0037025201 scopus 로고    scopus 로고
    • Sustained loss of a neoplastic phenotype by brief inactivation of MYC
    • Jain M, Arvanitis C, Chu K, et al. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science (NY) 2002;297: 102-104.
    • (2002) Science (NY) , vol.297 , pp. 102-104
    • Jain, M.1    Arvanitis, C.2    Chu, K.3
  • 93
    • 34247187543 scopus 로고    scopus 로고
    • Myc deletion rescues Apc deficiency in the small intestine
    • Sansom OJ, Meniel VS, Muncan V, et al. Myc deletion rescues Apc deficiency in the small intestine. Nature 2007;446:676-679.
    • (2007) Nature , vol.446 , pp. 676-679
    • Sansom, O.J.1    Meniel, V.S.2    Muncan, V.3
  • 94
    • 7744220635 scopus 로고    scopus 로고
    • MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • Shachaf CM, Kopelman AM, Arvanitis C, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004;431:1112-1117.
    • (2004) Nature , vol.431 , pp. 1112-1117
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3
  • 95
    • 0022572014 scopus 로고
    • Alterations of myc, myb, and rasHa proto-oncogenes in cancers are frequent and show clinical correlation
    • Yokota J, Tsunetsugu-Yokota Y, Battifora H, et al. Alterations of myc, myb, and rasHa proto-oncogenes in cancers are frequent and show clinical correlation. Science (NY) 1986;231:261-265.
    • (1986) Science (NY) , vol.231 , pp. 261-265
    • Yokota, J.1    Tsunetsugu-Yokota, Y.2    Battifora, H.3
  • 96
    • 0033598978 scopus 로고    scopus 로고
    • Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability
    • Georgiades IB, Curtis LJ, Morris RM, et al. Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability. Oncogene 1999;18:7933-7940.
    • (1999) Oncogene , vol.18 , pp. 7933-7940
    • Georgiades, I.B.1    Curtis, L.J.2    Morris, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.