메뉴 건너뛰기




Volumn 23, Issue 1-2, 2004, Pages 63-75

Role of cyclooxygenase-2 in colorectal cancer

Author keywords

Colorectal cancer; Coxibs; Cyclooxygenase 2; NSAIDs; Tumorigenesis

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; NS 983; PROSTACYCLIN; ROFECOXIB; SULFIDE; SULFONE DERIVATIVE; SULINDAC; SULINDAC SULFIDE; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 1242314857     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025863029529     Document Type: Review
Times cited : (185)

References (121)
  • 2
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun MJ, Namboodiri MM, Heath CW Jr. Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 325(23): 1593-1596, 1991
    • (1991) N Engl J Med , vol.325 , Issue.23 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 6
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
    • DuBois RN, Radhika A, Reddy BS, Entingh AJ: Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology 110(4): 1259-1262, 1996
    • (1996) Gastroenterology , vol.110 , Issue.4 , pp. 1259-1262
    • DuBois, R.N.1    Radhika, A.2    Reddy, B.S.3    Entingh, A.J.4
  • 9
    • 0032006784 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
    • Kawamori T, Rao CV, Seibert K, Reddy BS: Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 58(3): 409-412, 1998
    • (1998) Cancer Res , vol.58 , Issue.3 , pp. 409-412
    • Kawamori, T.1    Rao, C.V.2    Seibert, K.3    Reddy, B.S.4
  • 14
    • 0033971402 scopus 로고    scopus 로고
    • Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointestinal toxicity?
    • Feldman M, McMahon AT: Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointestinal toxicity? Ann Intern Med 132(2): 134-143, 2001
    • (2001) Ann Intern Med , vol.132 , Issue.2 , pp. 134-143
    • Feldman, M.1    McMahon, A.T.2
  • 16
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM: Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69: 145-182, 2000
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 18
    • 0029583372 scopus 로고
    • Inflammation, reproduction, cancer and all that... The regulation and role of the inducible prostaglandin synthase
    • Herschman HR, Xie W, Reddy S: Inflammation, reproduction, cancer and all that.... The regulation and role of the inducible prostaglandin synthase. Bioessays 17(12): 1031-1037, 1995
    • (1995) Bioessays , vol.17 , Issue.12 , pp. 1031-1037
    • Herschman, H.R.1    Xie, W.2    Reddy, S.3
  • 19
    • 0030049390 scopus 로고    scopus 로고
    • Prostaglandin synthase 2
    • Herschman HR: Prostaglandin synthase 2. Biochim Biophys Acta 1299(1): 125-140, 1996
    • (1996) Biochim Biophys Acta , vol.1299 , Issue.1 , pp. 125-140
    • Herschman, H.R.1
  • 20
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • Xie WL, Chipman JG, Robertson DL, Erikson RL, Simmons DL: Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88(7): 2692-2696, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.7 , pp. 2692-2696
    • Xie, W.L.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.L.4    Simmons, D.L.5
  • 21
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR: TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 266(20): 12866-12872, 1991
    • (1991) J Biol Chem , vol.266 , Issue.20 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 22
    • 0026730021 scopus 로고
    • Human cyclooxygenase-2 cDNA
    • Hla T, Neilson K: Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 89(16): 7384-7388, 1992
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.16 , pp. 7384-7388
    • Hla, T.1    Neilson, K.2
  • 24
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • FitzGerald GA, Patrono C: The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 345(6): 433-442, 2001
    • (2001) N Engl J Med , vol.345 , Issue.6 , pp. 433-442
    • FitzGerald, G.A.1    Patrono, C.2
  • 25
    • 0032702213 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibitors: Discovery, selectivity and the future
    • Marnett LJ, Kalgutkar AS: Cyclooxygenase 2 inhibitors: Discovery, selectivity and the future. Trends Pharmacol Sci 20(11): 465-469, 1999
    • (1999) Trends Pharmacol Sci , vol.20 , Issue.11 , pp. 465-469
    • Marnett, L.J.1    Kalgutkar, A.S.2
  • 26
    • 0032815687 scopus 로고    scopus 로고
    • Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers
    • Sinicrope FA, Lemoine M, Xi L, Lynch PM, Cleary KR, Shen Y, Frazier ML: Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers. Gastroenterology 117(2): 350-358, 1999
    • (1999) Gastroenterology , vol.117 , Issue.2 , pp. 350-358
    • Sinicrope, F.A.1    Lemoine, M.2    Xi, L.3    Lynch, P.M.4    Cleary, K.R.5    Shen, Y.6    Frazier, M.L.7
  • 29
    • 0032833473 scopus 로고    scopus 로고
    • High expression of cyclooxygenase-2 in macrophages of human colonic adenoma
    • Bamba H, Ota S, Kato A, Adachi A, Itoyama S, Matsuzaki F: High expression of cyclooxygenase-2 in macrophages of human colonic adenoma. Int J Cancer 83(4): 470-475, 1999
    • (1999) Int J Cancer , vol.83 , Issue.4 , pp. 470-475
    • Bamba, H.1    Ota, S.2    Kato, A.3    Adachi, A.4    Itoyama, S.5    Matsuzaki, F.6
  • 33
    • 0037086261 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ
    • Half E, Tang XM, Gwyn K, Sahin A, Wathen K, Sinicrope FA: Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ. Cancer Res 62(6): 1676-1681, 2002
    • (2002) Cancer Res , vol.62 , Issue.6 , pp. 1676-1681
    • Half, E.1    Tang, X.M.2    Gwyn, K.3    Sahin, A.4    Wathen, K.5    Sinicrope, F.A.6
  • 34
    • 0033199017 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs
    • Molina MA, Sitja-Arnau M, Lemoine MG, Frazier ML, Sinicrope FA: Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs. Cancer Res 59(17): 4356-4362, 1999
    • (1999) Cancer Res , vol.59 , Issue.17 , pp. 4356-4362
    • Molina, M.A.1    Sitja-Arnau, M.2    Lemoine, M.G.3    Frazier, M.L.4    Sinicrope, F.A.5
  • 36
    • 0033173218 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in Barrett's esophagus, Barrett's adenocarcinomas, and esophageal SCC: Ready for clinical trials
    • Lord RV, Danenberg KD, Danenberg PV: Cyclooxygenase-2 in Barrett's esophagus, Barrett's adenocarcinomas, and esophageal SCC: Ready for clinical trials. Am J Gastroenterol 94(8): 2313-2315, 1999
    • (1999) Am J Gastroenterol , vol.94 , Issue.8 , pp. 2313-2315
    • Lord, R.V.1    Danenberg, K.D.2    Danenberg, P.V.3
  • 39
    • 0036229792 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia
    • Yamagata R, Shimoyama T, Fukuda S, Yoshimura T, Tanaka M, Munakata A: Cyclooxygenase-2 expression is increased in early intestinal-type gastric cancer and gastric mucosa with intestinal metaplasia. Eur J Gastroenterol Hepatol 14(4): 359-363, 2002
    • (2002) Eur J Gastroenterol Hepatol , vol.14 , Issue.4 , pp. 359-363
    • Yamagata, R.1    Shimoyama, T.2    Fukuda, S.3    Yoshimura, T.4    Tanaka, M.5    Munakata, A.6
  • 42
    • 0033918259 scopus 로고    scopus 로고
    • Differential expression of cyclooxygenase 2 in human colorectal cancer
    • Hull M, Langman M: Differential expression of cyclooxygenase 2 in human colorectal cancer. Gut 47(1): 154, 2000
    • (2000) Gut , vol.47 , Issue.1 , pp. 154
    • Hull, M.1    Langman, M.2
  • 45
    • 0036895867 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps
    • Sonoshita M, Takaku K, Oshima M, Sugihara K, Taketo MM: Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps. Cancer Res 62(23): 6846-6849, 2002
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6846-6849
    • Sonoshita, M.1    Takaku, K.2    Oshima, M.3    Sugihara, K.4    Taketo, M.M.5
  • 49
    • 0034681117 scopus 로고    scopus 로고
    • Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype
    • Toyota M, Ohe-Toyota M, Ahuja N, Issa JP: Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype. Proc Natl Acad Sci USA 97(2): 710-715, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.2 , pp. 710-715
    • Toyota, M.1    Ohe-Toyota, M.2    Ahuja, N.3    Issa, J.P.4
  • 50
    • 0035881311 scopus 로고    scopus 로고
    • Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor
    • Lal G, Ash C, Hay K, Redston M, Kwong E, Hancock B, Mak T, Kargman S, Evans JF, Gallinger S: Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. Cancer Res 61(16): 6131-6136, 2001
    • (2001) Cancer Res , vol.61 , Issue.16 , pp. 6131-6136
    • Lal, G.1    Ash, C.2    Hay, K.3    Redston, M.4    Kwong, E.5    Hancock, B.6    Mak, T.7    Kargman, S.8    Evans, J.F.9    Gallinger, S.10
  • 52
    • 0028200879 scopus 로고
    • Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents
    • Pereira MA, Barnes LH, Rassman VL, Kelloff GV, Steele VE: Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents. Carcinogenesis 15(5): 1049-1054, 1994
    • (1994) Carcinogenesis , vol.15 , Issue.5 , pp. 1049-1054
    • Pereira, M.A.1    Barnes, L.H.2    Rassman, V.L.3    Kelloff, G.V.4    Steele, V.E.5
  • 53
    • 0034650771 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis
    • Reddy BS, Hirose Y, Lubet R, Steele V, Kelloff G, Paulson S, Seibert K, Rao CV: Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res 60(2): 293-297, 2000
    • (2000) Cancer Res , vol.60 , Issue.2 , pp. 293-297
    • Reddy, B.S.1    Hirose, Y.2    Lubet, R.3    Steele, V.4    Kelloff, G.5    Paulson, S.6    Seibert, K.7    Rao, C.V.8
  • 55
    • 0034665122 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
    • Jacoby RF, Seibert K, Cole CE, Kelloff G, Lubet RA: The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 60(18): 5040-5044, 2000
    • (2000) Cancer Res , vol.60 , Issue.18 , pp. 5040-5044
    • Jacoby, R.F.1    Seibert, K.2    Cole, C.E.3    Kelloff, G.4    Lubet, R.A.5
  • 56
    • 0035866401 scopus 로고    scopus 로고
    • Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
    • Oshima M, Murai N, Kargman S, Arguello M, Luk P, Kwong E, Taketo MM, Evans JF: Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 61(4): 1733-1740, 2001
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1733-1740
    • Oshima, M.1    Murai, N.2    Kargman, S.3    Arguello, M.4    Luk, P.5    Kwong, E.6    Taketo, M.M.7    Evans, J.F.8
  • 58
    • 0035912711 scopus 로고    scopus 로고
    • Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin
    • Neufang G, Furstenberger G, Heidt M, Marks F, Muller-Decker K: Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin. Proc Natl Acad Sci USA 98(13): 7629-7634, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.13 , pp. 7629-7634
    • Neufang, G.1    Furstenberger, G.2    Heidt, M.3    Marks, F.4    Muller-Decker, K.5
  • 61
    • 0029825362 scopus 로고    scopus 로고
    • Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling
    • Moss SF, Scholes JV, Holt PR: Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling. Dig Dis Sci 41(11): 2238-2247, 1996
    • (1996) Dig Dis Sci , vol.41 , Issue.11 , pp. 2238-2247
    • Moss, S.F.1    Scholes, J.V.2    Holt, P.R.3
  • 62
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN: Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83(3): 493-501, 1995
    • (1995) Cell , vol.83 , Issue.3 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 63
    • 0036829336 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells
    • Sun Y, Tang XM, Half E, Kuo MT, Sinicrope FA: Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. Cancer Res 62(21): 6323-6328, 2002
    • (2002) Cancer Res , vol.62 , Issue.21 , pp. 6323-6328
    • Sun, Y.1    Tang, X.M.2    Half, E.3    Kuo, M.T.4    Sinicrope, F.A.5
  • 64
    • 0036735391 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis- inducing ligand-induced apoptosis in human colon cancer cells
    • Tang X, Sun YJ, Half E, Kuo MT, Sinicrope F: Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells. Cancer Res 62(17): 4903-4908, 2002
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4903-4908
    • Tang, X.1    Sun, Y.J.2    Half, E.3    Kuo, M.T.4    Sinicrope, F.5
  • 65
    • 0037026582 scopus 로고    scopus 로고
    • Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells
    • He Q, Luo X, Huang Y, Sheikh MS: Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells. Oncogene 21(39): 6032-6040, 2002
    • (2002) Oncogene , vol.21 , Issue.39 , pp. 6032-6040
    • He, Q.1    Luo, X.2    Huang, Y.3    Sheikh, M.S.4
  • 66
    • 0032901304 scopus 로고    scopus 로고
    • Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms
    • Shattuck-Brandt RL, Lamps LW, Heppner Goss KJ, DuBois RN, Matrisian LM: Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. Mol Carcinog 24(3): 177-187, 1999
    • (1999) Mol Carcinog , vol.24 , Issue.3 , pp. 177-187
    • Shattuck-Brandt, R.L.1    Lamps, L.W.2    Heppner Goss, K.J.3    DuBois, R.N.4    Matrisian, L.M.5
  • 67
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii M, Kawano S, DuBois RN: Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 94(7): 3336-3340, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.7 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 68
    • 0036926092 scopus 로고    scopus 로고
    • Cyclooxygenase-2 increased the angiogenic and metastatic potential of tumor cells
    • Li G, Yang T, Yan J: Cyclooxygenase-2 increased the angiogenic and metastatic potential of tumor cells. Biochem Biophys Res Commun 299(5): 886-886, 2002
    • (2002) Biochem Biophys Res Commun , vol.299 , Issue.5 , pp. 886-886
    • Li, G.1    Yang, T.2    Yan, J.3
  • 69
    • 0034662627 scopus 로고    scopus 로고
    • Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases
    • Attiga FA, Fernandez PM, Weeraratna AT, Manyak MJ, Patierno SR: Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. Cancer Res 60(16): 4629-4637, 2000
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4629-4637
    • Attiga, F.A.1    Fernandez, P.M.2    Weeraratna, A.T.3    Manyak, M.J.4    Patierno, S.R.5
  • 70
    • 0020967295 scopus 로고
    • Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat
    • Peterson HI: Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat. Invasion Metastasis 3(3): 151-159, 1983
    • (1983) Invasion Metastasis , vol.3 , Issue.3 , pp. 151-159
    • Peterson, H.I.1
  • 71
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
    • Jones MK, Wang H, Peskar BM, Levin E, Itani RM, Sarfeh IJ, Tarnawski AS: Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 5(12): 1418-1423, 1999
    • (1999) Nat Med , vol.5 , Issue.12 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3    Levin, E.4    Itani, R.M.5    Sarfeh, I.J.6    Tarnawski, A.S.7
  • 72
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN: Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93(5): 705-716, 1998
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 73
    • 0034029780 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants
    • Majima M, Hayashi I, Muramatsu M, Katada J, Yamashina S, Katori M: Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants. Br J Pharmacol 130(3): 641-649, 2000
    • (2000) Br J Pharmacol , vol.130 , Issue.3 , pp. 641-649
    • Majima, M.1    Hayashi, I.2    Muramatsu, M.3    Katada, J.4    Yamashina, S.5    Katori, M.6
  • 75
    • 0033567459 scopus 로고    scopus 로고
    • Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis
    • Daniel TO, Liu H, Morrow JD, Crews BC, Marnett LJ: Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Res 59(18): 4574-4577, 1999
    • (1999) Cancer Res , vol.59 , Issue.18 , pp. 4574-4577
    • Daniel, T.O.1    Liu, H.2    Morrow, J.D.3    Crews, B.C.4    Marnett, L.J.5
  • 77
    • 0030879456 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression
    • Elder DJ, Halton DE, Hague A, Paraskeva C: Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: Independence from COX-2 protein expression Clin Cancer Res 3(10): 1679-1683, 1997
    • (1997) Clin Cancer Res , vol.3 , Issue.10 , pp. 1679-1683
    • Elder, D.J.1    Halton, D.E.2    Hague, A.3    Paraskeva, C.4
  • 79
    • 0029115954 scopus 로고
    • Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells
    • Shiff SJ, Qiao L, Tsai LL, Rigas B: Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells. J Clin Invest 96(1): 491-503, 1995
    • (1995) J Clin Invest , vol.96 , Issue.1 , pp. 491-503
    • Shiff, S.J.1    Qiao, L.2    Tsai, L.L.3    Rigas, B.4
  • 81
    • 0034326837 scopus 로고    scopus 로고
    • Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models
    • Williams CS, Watson AJ, Sheng H, Helou R, Shao J, DuBois RN: Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models. Cancer Res 60(21): 6045-6051, 2000
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 6045-6051
    • Williams, C.S.1    Watson, A.J.2    Sheng, H.3    Helou, R.4    Shao, J.5    DuBois, R.N.6
  • 82
    • 0031000902 scopus 로고    scopus 로고
    • Modulation of apoptosis by sulindac, curcumin, phenylethyl-3- methylcaffeate, and 6-phenylhexyl isothiocyanate: Apoptotic index as a biomarker in colon cancer chemoprevention and promotion
    • Samaha HS, Kelloff GJ, Steele V, Rao CV, Reddy BS: Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: Apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res 57(7): 1301-1305, 1997
    • (1997) Cancer Res , vol.57 , Issue.7 , pp. 1301-1305
    • Samaha, H.S.1    Kelloff, G.J.2    Steele, V.3    Rao, C.V.4    Reddy, B.S.5
  • 85
    • 0034602188 scopus 로고    scopus 로고
    • Role of BAX in the apoptotic response to anticancer agents
    • Zhang L, Yu J, Park BH, Kinzler KW, Vogelstein B: Role of BAX in the apoptotic response to anticancer agents. Science 290(5493): 989-992, 2000
    • (2000) Science , vol.290 , Issue.5493 , pp. 989-992
    • Zhang, L.1    Yu, J.2    Park, B.H.3    Kinzler, K.W.4    Vogelstein, B.5
  • 86
    • 0030602860 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway
    • Hanif R, Pittas A, Feng Y, Koutsos MI, Qiao L, Staiano-Coico L, Shiff SI, Rigas B: Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem Pharmacol 52(2): 237-245, 1996
    • (1996) Biochem Pharmacol , vol.52 , Issue.2 , pp. 237-245
    • Hanif, R.1    Pittas, A.2    Feng, Y.3    Koutsos, M.I.4    Qiao, L.5    Staiano-Coico, L.6    Shiff, S.I.7    Rigas, B.8
  • 87
    • 0033575760 scopus 로고    scopus 로고
    • Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
    • Zhang X, Morham SG, Langenbach R, Young DA: Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J Exp Med 190(4): 451-459, 1999
    • (1999) J Exp Med , vol.190 , Issue.4 , pp. 451-459
    • Zhang, X.1    Morham, S.G.2    Langenbach, R.3    Young, D.A.4
  • 89
    • 0034019416 scopus 로고    scopus 로고
    • Apoptosis induction and cyclooxygenase-2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase-2-selective non- Steroidal anti-inflammatory drug NS-398
    • Elder DJ, Halton DE, Crew TE, Paraskeva C: Apoptosis induction and cyclooxygenase-2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase-2-selective non-steroidal anti-inflammatory drug NS-398. Int J Cancer 86(4): 553-560, 2000
    • (2000) Int J Cancer , vol.86 , Issue.4 , pp. 553-560
    • Elder, D.J.1    Halton, D.E.2    Crew, T.E.3    Paraskeva, C.4
  • 92
    • 0028167846 scopus 로고
    • Inhibition of NF-kappa B by sodium salicylate and aspirin
    • Kopp E, Ghosh S: Inhibition of NF-kappa B by sodium salicylate and aspirin. Science 265(5174): 956-959, 1994
    • (1994) Science , vol.265 , Issue.5174 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 93
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibits activation of the NF-kappaB pathway
    • Yamamoto Y, Yin MJ, Lin KM, Gaynor RB: Sulindac inhibits activation of the NF-kappaB pathway. J Biol Chem 274(38): 27307-27314, 1999
    • (1999) J Biol Chem , vol.274 , Issue.38 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 94
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
    • Yin MJ, Yamamoto Y, Gaynor RB: The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 396(6706): 77-80, 1998
    • (1998) Nature , vol.396 , Issue.6706 , pp. 77-80
    • Yin, M.J.1    Yamamoto, Y.2    Gaynor, R.B.3
  • 95
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann JM, Lenhard JM, Oliver BB, Ringold GM, Kliewer SA: Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 272(6): 3406-3410, 1997
    • (1997) J Biol Chem , vol.272 , Issue.6 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 96
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He TC, Chan TA, Vogelstein B, Kinzler KW: PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99(3): 335-345, 1999
    • (1999) Cell , vol.99 , Issue.3 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 97
    • 0035956850 scopus 로고    scopus 로고
    • Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
    • Park BH, Vogelstein B, Kinzler KW: Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc Natl Acad Sci USA 98(5): 2598-2603, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.5 , pp. 2598-2603
    • Park, B.H.1    Vogelstein, B.2    Kinzler, K.W.3
  • 98
    • 0030025365 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and breast cancer
    • Harris RE, Namboodiri KK, Farrar WB: Nonsteroidal antiinflammatory drugs and breast cancer. Epidemiology 7(2): 203-205, 1996
    • (1996) Epidemiology , vol.7 , Issue.2 , pp. 203-205
    • Harris, R.E.1    Namboodiri, K.K.2    Farrar, W.B.3
  • 99
    • 0034039306 scopus 로고    scopus 로고
    • Nested case-control study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage
    • Sharpe CR, Collet JP, McNutt M, Belzile E, Boivin JF, Hanley JA: Nested case-control study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage. Br J Cancer 83(1): 112-120, 2000
    • (2000) Br J Cancer , vol.83 , Issue.1 , pp. 112-120
    • Sharpe, C.R.1    Collet, J.P.2    McNutt, M.3    Belzile, E.4    Boivin, J.F.5    Hanley, J.A.6
  • 104
    • 0029851291 scopus 로고    scopus 로고
    • Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines
    • Liu XH, Rose DP: Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines. Cancer Res 56(22): 5125-5127, 1996
    • (1996) Cancer Res , vol.56 , Issue.22 , pp. 5125-5127
    • Liu, X.H.1    Rose, D.P.2
  • 105
    • 0037166271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: Evidence for involvement of AP-1 and PEA3
    • Subbaramaiah K, Norton L, Gerald W, Dannenberg AJ: Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: Evidence for involvement of AP-1 and PEA3. J Biol Chem 277(21): 18649-18657, 2002
    • (2002) J Biol Chem , vol.277 , Issue.21 , pp. 18649-18657
    • Subbaramaiah, K.1    Norton, L.2    Gerald, W.3    Dannenberg, A.J.4
  • 111
    • 0034706411 scopus 로고    scopus 로고
    • Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis
    • Watson DJ, Harper SE, Zhao PL, Quan H, Bolognese JA, Simon TJ: Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis. Arch Intern Med 160(19): 2998-3003, 2000
    • (2000) Arch Intern Med , vol.160 , Issue.19 , pp. 2998-3003
    • Watson, D.J.1    Harper, S.E.2    Zhao, P.L.3    Quan, H.4    Bolognese, J.A.5    Simon, T.J.6
  • 112
    • 0036789104 scopus 로고    scopus 로고
    • Stratifying the risk of NSAID-related upper gastrointestinal clinical events: Results of a double-blind outcomes study in patients with rheumatoid arthritis
    • Laine L, Bombardier C, Hawkey CJ, Davis B, Shapiro D, Brett C, Reicin A: Stratifying the risk of NSAID-related upper gastrointestinal clinical events: Results of a double-blind outcomes study in patients with rheumatoid arthritis. Gastroenterology 123(4): 1006-1012, 2002
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1006-1012
    • Laine, L.1    Bombardier, C.2    Hawkey, C.J.3    Davis, B.4    Shapiro, D.5    Brett, C.6    Reicin, A.7
  • 114
    • 0037027050 scopus 로고    scopus 로고
    • COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease
    • Ray WA, Stein CM, Daugherty JR, Hall K, Arbogast PG, Griffin MR: COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. Lancet 360(9339): 1071-1073, 2002
    • (2002) Lancet , vol.360 , Issue.9339 , pp. 1071-1073
    • Ray, W.A.1    Stein, C.M.2    Daugherty, J.R.3    Hall, K.4    Arbogast, P.G.5    Griffin, M.R.6
  • 115
    • 0035934070 scopus 로고    scopus 로고
    • Risk of cardiovascular events associated with selective COX-2 inhibitors
    • Mukherjee D, Nissen SE, Topol EJ: Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 286(8): 954-959, 2001
    • (2001) JAMA , vol.286 , Issue.8 , pp. 954-959
    • Mukherjee, D.1    Nissen, S.E.2    Topol, E.J.3
  • 117
    • 0037311125 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice
    • Yao M, Kargman S, Lam EC, Kelly CR, Zheng Y, Luk P, Kwong E, Evans JF, Wolfe MM: Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. Cancer Res 63(3): 586-592, 2003
    • (2003) Cancer Res , vol.63 , Issue.3 , pp. 586-592
    • Yao, M.1    Kargman, S.2    Lam, E.C.3    Kelly, C.R.4    Zheng, Y.5    Luk, P.6    Kwong, E.7    Evans, J.F.8    Wolfe, M.M.9
  • 119
    • 0030070735 scopus 로고    scopus 로고
    • Phase I trial of sulindac plus 5-fluorouracil and levamisole: Potential adjuvant therapy for colon carcinoma
    • Sinicrope FA, Pazdur R, Levin B: Phase I trial of sulindac plus 5-fluorouracil and levamisole: Potential adjuvant therapy for colon carcinoma. Clin Cancer Res 2(1): 37-41, 1996
    • (1996) Clin Cancer Res , vol.2 , Issue.1 , pp. 37-41
    • Sinicrope, F.A.1    Pazdur, R.2    Levin, B.3
  • 120


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.