Dissecting karyotypic patterns in colorectal tumors: Two distinct but overlapping pathways in the adenoma-carcinoma transition

Cancer Research

Volumn 62, Issue 20, 2002, Pages 5939-5946

  Höglund, Mattias ^a   Gisselsson, David ^a   Hansen, Gunnar B ^a   Säll, Torbjörn ^b   Mitelman, Felix ^a   Nilbert, Mef ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMA; ARTICLE; CARCINOMA; CELL TRANSFORMATION; CHROMOSOME 12P; CHROMOSOME 1P; CHROMOSOME 7Q; CHROMOSOME ABERRATION; COLORECTAL TUMOR; CONTROLLED STUDY; CYTOGENETICS; DISEASE COURSE; EVOLUTION; HUMAN; HUMAN CELL; HUMAN TISSUE; KARYOTYPE; MALIGNANT TRANSFORMATION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADENOMA; CARCINOMA; CHROMOSOME ABERRATIONS; COLORECTAL NEOPLASMS; DATABASES, GENETIC; DISEASE PROGRESSION; HUMANS; KARYOTYPING; NUCLEIC ACID HYBRIDIZATION;

EID: 0037108710     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Pisani, P., Parkin, M. D., Bray, F., and Ferlay, J. Estimates of the worldwide mortality from 25 cancers in 1990. Int. J. Cancer, 83: 18-29, 1999.
2. Houlston, R. S., and Tomlinson, I. P. M. Genetic prognostic markers in colorectal cancer. J. Clin. Pathol. Mol. Pathol., 50: 281-288, 1997.
3. Fearon, E., and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759-767, 1990.
4. Lengauer, C., Kinzler, K. W., and Vogelstein, B. Genetic instability in colorectal cancers. Nature (Lond.), 386: 623-627, 1997.
5. Thibodeau, S. N., Bren, G., and Dchaid, D. Microsatellite instability in cancer of the proximal colon. Science (Wash. DC), 260: 816-819, 1993.
6. Bardi, G., Sukhikh, T., Pandis, N., Fenger, C., Kronborg, O., and Heim, S. Karyotypic characterization of colorectal adenocarcinomas. Genes Chromosomes Cancer, 12: 97-109, 1995.
7. Heim, S., and Mitelman, F. Cancer Cytogenetics, New York: Wiley-Liss, 1995.
8. Ried, T., Knutzen, R., Steinbeck, R., Blegen, H., Schrock, E., Heselmayer, K., du Manoir, S., and Auer, G. Comparative genomic hybridization reveals a specific pattern of gains and losses during the genesis of colorectal tumors. Genes Chromosomes Cancer, 15: 234-245, 1996.
9. Meijer, G. A., Hermsen, M. A., Baak, J. P., van Diest, P. J., Meuwissen, S. G., Belien, J. A., Hoovers, J. M., Joenje, H., Snijders, P. J., and Walboomers, J. M. Progression from adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation. J. Clin. Pathol., 51: 901-909, 1998.
10. DeAngelis, P. M., Calusen, O. P. F, Schjolberg, A., and Stokke, T. Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour ploidy, genotypes and phenotypes. Br. J. Cancer. 80: 526-535, 1999.
11. Aragane, H., Sakamura, C., Nakanishi, M., Yasuoka, R., Fujita, Y., Tanguchi, H., Hagiwara, A., Yamagushi, T., Abe, T., Inazawa, J., and Yamagishi, H. Chromosomal aberrations in colorectal cancers and liver metastases analyzed by comparative genomic hybridization. Int. J. Cancer, 94: 623-629, 2001.
12. Zhou, W., Goodman, S. N., Galizia, G., Lieto, E., Ferraraccio, F., Pignatelli, C., Purdie, C. A., Piris, J., Morris, R., Harrison, D. J, Pay, P. B., Cuilford, A., Romans, K. E., Montgomery, E. A., Choti, M. A., Kinzler K. W., and Vogelstein, B. Counting alleles to predict recurrence of early-stage colorectal cancers. Lancet, 359: 219-225, 2002.
13. Höglund, M., Gisselsson. D., Mandahl, N., Johansson, B., Merterns, F., Mitelman, F., and Säll, T. Multivariate analyses of genomic imbalances in solid tumors reveal distinct and converging pathways of karyotypic evolution. Genes Chromosomes Cancer, 31: 156-171, 2001.
14. Höglund, M., Gisselsson, D., Säll, T., and Mitelman, F. Coping with complexity: Multivariate analysis of tumor karyotypes. Cancer Genet. Cytogenet., 135: 103-109, 2002.
15. Mooney, C. Z., and Duval, R. D. Bootstrapping: A Nonparametric Approach to Statistical Inference. Sage University Paper Series on Quantitative Applications in the Social Sciences, Series No. 07-095. Thousand Oaks, CA: Sage, 1993.
16. Höglund, M., Gisselsson, D., Hansen, G. B., Säll, T., and Mitelman, F. Multivariate analysis of chromosomal imbalances in breast cancer delineates cytogenetic pathways and reveals complex relationships among imbalances. Cancer Res., 62: 2675-2680, 2002.
17. Affifi, A., and Azen, S. (eds.). Statistical Analysis: A Computor Oriented Approach, pp. 318-324. New York: Academic Press, 1979.
18. Höglund, M., Säll, T., Heim, S., Mitelman, F., Mandahl, N., and Fadl-Elmula, I. Identification of cytogenetic subgroups and karyotypic pathways in transitional cell carcinoma. Cancer Res., 61: 8241-8246, 2001.
19. Clausen, S. Applied Correspondence Analysis: An Introduction. Sage University Papers Series on Quantitative Applications in the Social Sciences, Series No. 07-121. Thousand Oaks, CA: Sage, 1988.