-
1
-
-
0025894713
-
P53 mutations in human cancers
-
Hollstein, M.; Sidransky, D.; Vogelstein, B.; Harris, C.C. p53 mutations in human cancers. Science, 1991, 253(5015), 49-53.
-
(1991)
Science
, vol.253
, Issue.5015
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
2
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt, M.S.; Bennett, W.P.; Hollstein, M.; Harris, C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 1994, 54(18), 4855-4878.
-
(1994)
Cancer Res
, vol.54
, Issue.18
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
3
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y.; Maya, R.; Kazaz, A.; Oren, M. Mdm2 promotes the rapid degradation of p53. Nature, 1997, 387(6630), 296-299.
-
(1997)
Nature
, vol.387
, Issue.6630
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
4
-
-
0033959744
-
MDM2--master regulator of the p53 tumor suppressor protein
-
Momand, J.; Wu, H. H.; Dasgupta, G. MDM2--master regulator of the p53 tumor suppressor protein. Gene, 2000, 242(1-2), 15-29.
-
(2000)
Gene
, vol.242
, Issue.1-2
, pp. 15-29
-
-
Momand, J.1
Wu, H.H.2
Dasgupta, G.3
-
5
-
-
65349103899
-
Blinded by the Light: The Growing Complexity of p53
-
Vousden, K. H.; Prives, C. Blinded by the Light: The Growing Complexity of p53. Cell, 2009, 137(3), 413-431.
-
(2009)
Cell
, vol.137
, Issue.3
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
6
-
-
70349438905
-
The expanding universe of p53 targets
-
Menendez, D.; Inga, A.; Resnick, M. A. The expanding universe of p53 targets. Nat. Rev. Cancer, 2009, 9(10), 724-737.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.10
, pp. 724-737
-
-
Menendez, D.1
Inga, A.2
Resnick, M.A.3
-
7
-
-
70349459599
-
P53 and metabolism
-
Vousden, K. H.; Ryan, K. M. p53 and metabolism. Nat. Rev. Cancer, 2009, 9(10), 691-700.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.10
, pp. 691-700
-
-
Vousden, K.H.1
Ryan, K.M.2
-
8
-
-
41149105243
-
ROS and p53: A versatile partnership
-
Liu, B.; Chen, Y.; St Clair, D. K. ROS and p53: a versatile partnership. Free Radic. Biol. Med., 2008, 44(8), 1529-1535.
-
(2008)
Free Radic. Biol. Med
, vol.44
, Issue.8
, pp. 1529-1535
-
-
Liu, B.1
Chen, Y.2
St. Clair, D.K.3
-
9
-
-
67349086630
-
The mitochondrial p53 pathway
-
Vaseva, A. V.; Moll, U. M. The mitochondrial p53 pathway. Biochim. Biophys. Acta, 2009, 1787(5), 414-420.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, Issue.5
, pp. 414-420
-
-
Vaseva, A.V.1
Moll, U.M.2
-
10
-
-
27144488229
-
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
-
Achanta, G.; Sasaki, R.; Feng, L.; Carew, J. S.; Lu, W.; Pelicano, H.; Keating, M. J.; Huang, P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J., 2005, 24(19), 3482-3492.
-
(2005)
EMBO J
, vol.24
, Issue.19
, pp. 3482-3492
-
-
Achanta, G.1
Sasaki, R.2
Feng, L.3
Carew, J.S.4
Lu, W.5
Pelicano, H.6
Keating, M.J.7
Huang, P.8
-
11
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace, D. C. Mitochondrial diseases in man and mouse. Science, 1999, 283(5407), 1482-8.
-
(1999)
Science
, vol.283
, Issue.5407
, pp. 1482-1488
-
-
Wallace, D.C.1
-
13
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. On the origin of cancer cells. Science, 1956, 123(3191), 309-314.
-
(1956)
Science
, vol.123
, Issue.3191
, pp. 309-314
-
-
Warburg, O.1
-
14
-
-
58149136865
-
Roles of p53, MYC and HIF-1 in regulating glycolysis -the seventh hallmark of cancer
-
Yeung, S. J.; Pan, J.; Lee, M. H. Roles of p53, MYC and HIF-1 in regulating glycolysis -the seventh hallmark of cancer. Cell Mol. Life Sci., 2008, 65(24), 3981-3999.
-
(2008)
Cell Mol. Life Sci
, vol.65
, Issue.24
, pp. 3981-3999
-
-
Yeung, S.J.1
Pan, J.2
Lee, M.H.3
-
15
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
Schwartzenberg-Bar-Yoseph, F.; Armoni, M.; Karnieli, E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res., 2004, 64(7), 2627-2633.
-
(2004)
Cancer Res
, vol.64
, Issue.7
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
16
-
-
43049139541
-
P53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
-
Kawauchi, K.; Araki, K.; Tobiume, K.; Tanaka, N. p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat. Cell Biol., 2008, 10(5), 611-618.
-
(2008)
Nat. Cell Biol
, vol.10
, Issue.5
, pp. 611-618
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
17
-
-
62549161375
-
Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-Nacetyl glucosamine modification
-
Kawauchi, K.; Araki, K.; Tobiume, K.; Tanaka, N. Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-Nacetyl glucosamine modification. Proc. Natl. Acad Sci. U S A., 2009, 106(9), 3431-3436.
-
(2009)
Proc. Natl. Acad Sci. U S A
, vol.106
, Issue.9
, pp. 3431-3436
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
18
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh, H.; Lleonart, M. E.; Gil, J.; Wang, J.; Degan, P.; Peters, G.; Martinez, D.; Carnero, A.; Beach, D. Glycolytic enzymes can modulate cellular life span. Cancer Res., 2005, 65(1), 177-185.
-
(2005)
Cancer Res
, vol.65
, Issue.1
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
19
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad, K.; Tsuruta, A.; Selak, M. A.; Vidal, M. N.; Nakano, K.; Bartrons, R.; Gottlieb, E.; Vousden, K. H. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell, 2006, 126(1), 107-120.
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
20
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
Matoba, S.; Kang, J. G.; Patino, W. D.; Wragg, A.; Boehm, M.; Gavrilova, O.; Hurley, P. J.; Bunz, F.; Hwang, P. M. p53 regulates mitochondrial respiration. Science, 2006, 312(5780), 1650-1653.
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
21
-
-
0033257077
-
Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a wellcontrolled wild-type p53 expression system
-
Okamura, S.; Ng, C. C.; Koyama, K.; Takei, Y.; Arakawa, H.; Monden, M.; Nakamura, Y. Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a wellcontrolled wild-type p53 expression system. Oncol. Res., 1999, 11(6), 281-285.
-
(1999)
Oncol. Res
, vol.11
, Issue.6
, pp. 281-285
-
-
Okamura, S.1
Ng, C.C.2
Koyama, K.3
Takei, Y.4
Arakawa, H.5
Monden, M.6
Nakamura, Y.7
-
22
-
-
65449137587
-
Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis
-
Lebedeva, M. A.; Eaton, J. S.; Shadel, G. S. Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis. Biochim. Biophys. Acta, 2009, 1787(5), 328-334.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, Issue.5
, pp. 328-334
-
-
Lebedeva, M.A.1
Eaton, J.S.2
Shadel, G.S.3
-
23
-
-
70349655709
-
P53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content
-
11 p following 712
-
Park, J. Y.; Wang, P. Y.; Matsumoto, T.; Sung, H. J.; Ma, W.; Choi, J. W.; Anderson, S. A.; Leary, S. C.; Balaban, R. S.; Kang, J. G.; Hwang, P. M. p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content. Circ. Res., 2009, 105(7), 705-712, 11 p following 712.
-
(2009)
Circ. Res
, vol.105
, Issue.7
, pp. 705-712
-
-
Park, J.Y.1
Wang, P.Y.2
Matsumoto, T.3
Sung, H.J.4
Ma, W.5
Choi, J.W.6
Anderson, S.A.7
Leary, S.C.8
Balaban, R.S.9
Kang, J.G.10
Hwang, P.M.11
-
24
-
-
34249811206
-
Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion
-
Bourdon, A.; Minai, L.; Serre, V.; Jais, J. P.; Sarzi, E.; Aubert, S.; Chretien, D.; de Lonlay, P.; Paquis-Flucklinger, V.; Arakawa, H.; Nakamura, Y.; Munnich, A.; Rotig, A. Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nat. Genet., 2007, 39(6), 776-780.
-
(2007)
Nat. Genet
, vol.39
, Issue.6
, pp. 776-780
-
-
Bourdon, A.1
Minai, L.2
Serre, V.3
Jais, J.P.4
Sarzi, E.5
Aubert, S.6
Chretien, D.7
de Lonlay, P.8
Paquis-Flucklinger, V.9
Arakawa, H.10
Nakamura, Y.11
Munnich, A.12
Rotig, A.13
-
25
-
-
0035078395
-
Direct influence of the p53 tumor suppressor on mitochondrial biogenesis and function
-
Donahue, R. J.; Razmara, M.; Hoek, J. B.; Knudsen, T. B. Direct influence of the p53 tumor suppressor on mitochondrial biogenesis and function. FASEB J., 2001, 15(3), 635-644.
-
(2001)
FASEB J
, vol.15
, Issue.3
, pp. 635-644
-
-
Donahue, R.J.1
Razmara, M.2
Hoek, J.B.3
Knudsen, T.B.4
-
26
-
-
33645729664
-
The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells
-
Chen, D.; Yu, Z.; Zhu, Z.; Lopez, C. D. The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells. Cancer Res., 2006, 66(7), 3485-3494.
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3485-3494
-
-
Chen, D.1
Yu, Z.2
Zhu, Z.3
Lopez, C.D.4
-
27
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina, A. A.; Budanov, A. V.; Ilyinskaya, G. V.; Agapova, L. S.; Kravchenko, J. E.; Chumakov, P. M. The antioxidant function of the p53 tumor suppressor. Nat. Med., 2005, 11(12), 1306-1313.
-
(2005)
Nat. Med
, vol.11
, Issue.12
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
28
-
-
2142815107
-
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
-
Budanov, A. V.; Sablina, A. A.; Feinstein, E.; Koonin, E. V.; Chumakov, P. M. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science, 2004, 304(5670), 596-600.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 596-600
-
-
Budanov, A.V.1
Sablina, A.A.2
Feinstein, E.3
Koonin, E.V.4
Chumakov, P.M.5
-
29
-
-
11144356558
-
P53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis
-
Hussain, S. P.; Amstad, P.; He, P.; Robles, A.; Lupold, S.; Kaneko, I.; Ichimiya, M.; Sengupta, S.; Mechanic, L.; Okamura, S.; Hofseth, L. J.; Moake, M.; Nagashima, M.; Forrester, K. S.; Harris, C. C. p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis. Cancer Res., 2004, 64(7), 2350-2356.
-
(2004)
Cancer Res
, vol.64
, Issue.7
, pp. 2350-2356
-
-
Hussain, S.P.1
Amstad, P.2
He, P.3
Robles, A.4
Lupold, S.5
Kaneko, I.6
Ichimiya, M.7
Sengupta, S.8
Mechanic, L.9
Okamura, S.10
Hofseth, L.J.11
Moake, M.12
Nagashima, M.13
Forrester, K.S.14
Harris, C.C.15
-
30
-
-
1942520427
-
Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses
-
Yoon, K. A.; Nakamura, Y.; Arakawa, H. Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses. J. Hum. Genet., 2004, 49(3), 134-140.
-
(2004)
J. Hum. Genet
, vol.49
, Issue.3
, pp. 134-140
-
-
Yoon, K.A.1
Nakamura, Y.2
Arakawa, H.3
-
31
-
-
33751009381
-
Regulation of AIF expression by p53
-
Stambolsky, P.; Weisz, L.; Shats, I.; Klein, Y.; Goldfinger, N.; Oren, M.; Rotter, V. Regulation of AIF expression by p53. Cell Death Differ., 2006, 13(12), 2140-2149.
-
(2006)
Cell Death Differ
, vol.13
, Issue.12
, pp. 2140-2149
-
-
Stambolsky, P.1
Weisz, L.2
Shats, I.3
Klein, Y.4
Goldfinger, N.5
Oren, M.6
Rotter, V.7
-
32
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak, K.; Xia, Y.; Zweier, J. L.; Kinzler, K. W.; Vogelstein, B. A model for p53-induced apoptosis. Nature, 1997, 389(6648), 300-305.
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
33
-
-
69249123718
-
Proline oxidase functions as a mitochondrial tumor suppressor in human cancers
-
Liu, Y.; Borchert, G. L.; Donald, S. P.; Diwan, B. A.; Anver, M.; Phang, J. M. Proline oxidase functions as a mitochondrial tumor suppressor in human cancers. Cancer Res., 2009, 69(16), 6414-6422.
-
(2009)
Cancer Res
, vol.69
, Issue.16
, pp. 6414-6422
-
-
Liu, Y.1
Borchert, G.L.2
Donald, S.P.3
Diwan, B.A.4
Anver, M.5
Phang, J.M.6
-
34
-
-
67650087634
-
Regulation and function of proline oxidase under nutrient stress
-
Pandhare, J.; Donald, S. P.; Cooper, S. K.; Phang, J. M. Regulation and function of proline oxidase under nutrient stress. J. Cell Biochem., 2009, 107(4), 759-768.
-
(2009)
J. Cell Biochem
, vol.107
, Issue.4
, pp. 759-768
-
-
Pandhare, J.1
Donald, S.P.2
Cooper, S.K.3
Phang, J.M.4
-
35
-
-
0035266127
-
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species
-
Donald, S. P.; Sun, X. Y.; Hu, C. A.; Yu, J.; Mei, J. M.; Valle, D.; Phang, J. M. Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species. Cancer Res., 2001, 61(5), 1810-1815.
-
(2001)
Cancer Res
, vol.61
, Issue.5
, pp. 1810-1815
-
-
Donald, S.P.1
Sun, X.Y.2
Hu, C.A.3
Yu, J.4
Mei, J.M.5
Valle, D.6
Phang, J.M.7
-
36
-
-
24944529262
-
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells
-
Liu, Y.; Borchert, G. L.; Donald, S. P.; Surazynski, A.; Hu, C. A.; Weydert, C. J.; Oberley, L. W.; Phang, J. M. MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis, 2005, 26(8), 1335-1342.
-
(2005)
Carcinogenesis
, vol.26
, Issue.8
, pp. 1335-1342
-
-
Liu, Y.1
Borchert, G.L.2
Donald, S.P.3
Surazynski, A.4
Hu, C.A.5
Weydert, C.J.6
Oberley, L.W.7
Phang, J.M.8
-
37
-
-
70449093664
-
GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress
-
Ide, T.; Brown-Endres, L.; Chu, K.; Ongusaha, P. P.; Ohtsuka, T.; El-Deiry, W. S.; Aaronson, S. A.; Lee, S. W. GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress. Mol. Cell, 2009, 36(3), 379-392.
-
(2009)
Mol. Cell
, vol.36
, Issue.3
, pp. 379-392
-
-
Ide, T.1
Brown-Endres, L.2
Chu, K.3
Ongusaha, P.P.4
Ohtsuka, T.5
El-Deiry, W.S.6
Aaronson, S.A.7
Lee, S.W.8
-
38
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton, D.; Wilkinson, S.; O'Prey, J.; Syed, N.; Smith, P.; Harrison, P. R.; Gasco, M.; Garrone, O.; Crook, T.; Ryan, K. M. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell, 2006, 126(1), 121-134.
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
39
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
Feng, Z.; Zhang, H.; Levine, A. J.; Jin, S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc. Natl. Acad Sci. U S A., 2005, 102(23), 8204-8209.
-
(2005)
Proc. Natl. Acad Sci. U S A
, vol.102
, Issue.23
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
40
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
Ravikumar, B.; Vacher, C.; Berger, Z.; Davies, J. E.; Luo, S.; Oroz, L. G.; Scaravilli, F.; Easton, D. F.; Duden, R.; O'Kane, C. J.; Rubinsztein, D. C. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet, 2004, 36(6), 585-595.
-
(2004)
Nat Genet
, vol.36
, Issue.6
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
41
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi, R. K.; Yu, D.; Lum, J. J.; Bui, T.; Christophorou, M. A.; Evan, G. I.; Thomas-Tikhonenko, A.; Thompson, C. B. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J. Clin. Invest., 2007, 117(2), 326-336.
-
(2007)
J. Clin. Invest
, vol.117
, Issue.2
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
Thomas-Tikhonenko, A.7
Thompson, C.B.8
-
42
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang, H.; Bosch-Marce, M.; Shimoda, L. A.; Tan, Y. S.; Baek, J. H.; Wesley, J. B.; Gonzalez, F. J.; Semenza, G. L. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J. Biol. Chem., 2008, 283(16), 10892-10903.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.16
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
43
-
-
50249145608
-
A dual role of p53 in the control of autophagy
-
Tasdemir, E.; Chiara Maiuri, M.; Morselli, E.; Criollo, A.; D'Amelio, M.; Djavaheri-Mergny, M.; Cecconi, F.; Tavernarakis, N.; Kroemer, G. A dual role of p53 in the control of autophagy. Autophagy, 2008, 4(6), 810-814.
-
(2008)
Autophagy
, vol.4
, Issue.6
, pp. 810-814
-
-
Tasdemir, E.1
Chiara, M.M.2
Morselli, E.3
Criollo, A.4
D'amelio, M.5
Djavaheri-Mergny, M.6
Cecconi, F.7
Tavernarakis, N.8
Kroemer, G.9
-
44
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
Tasdemir, E.; Maiuri, M. C.; Galluzzi, L.; Vitale, I.; Djavaheri-Mergny, M.; D'Amelio, M.; Criollo, A.; Morselli, E.; Zhu, C.; Harper, F.; Nannmark, U.; Samara, C.; Pinton, P.; Vicencio, J. M.; Carnuccio, R.; Moll, U. M.; Madeo, F.; Paterlini-Brechot, P.; Rizzuto, R.; Szabadkai, G.; Pierron, G.; Blomgren, K.; Tavernarakis, N.; Codogno, P.; Cecconi, F.; Kroemer, G. Regulation of autophagy by cytoplasmic p53. Nat. Cell Biol., 2008, 10(6), 676-687.
-
(2008)
Nat. Cell Biol
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
45
-
-
70350575440
-
Modulation of intracellular ROS levels by TIGAR controls autophagy
-
Bensaad, K.; Cheung, E. C.; Vousden, K. H. Modulation of intracellular ROS levels by TIGAR controls autophagy. EMBO J., 2009, 28(19), 3015-3026.
-
(2009)
EMBO J
, vol.28
, Issue.19
, pp. 3015-3026
-
-
Bensaad, K.1
Cheung, E.C.2
Vousden, K.H.3
-
46
-
-
48449101433
-
P53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
-
Budanov, A. V.; Karin, M. p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell, 2008, 134(3), 451-460.
-
(2008)
Cell
, vol.134
, Issue.3
, pp. 451-460
-
-
Budanov, A.V.1
Karin, M.2
-
47
-
-
34248194200
-
The regulation of AMPK beta1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
-
Feng, Z.; Hu, W.; de Stanchina, E.; Teresky, A. K.; Jin, S.; Lowe, S.; Levine, A. J. The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res., 2007, 67(7), 3043-3053.
-
(2007)
Cancer Res
, vol.67
, Issue.7
, pp. 3043-3053
-
-
Feng, Z.1
Hu, W.2
de Stanchina, E.3
Teresky, A.K.4
Jin, S.5
Lowe, S.6
Levine, A.J.7
-
48
-
-
0029885334
-
Repression of the insulin receptor promoter by the tumor suppressor gene product p53: A possible mechanism for receptor overexpression in breast cancer
-
Webster, N. J.; Resnik, J. L.; Reichart, D. B.; Strauss, B.; Haas, M.; Seely, B. L. Repression of the insulin receptor promoter by the tumor suppressor gene product p53: a possible mechanism for receptor overexpression in breast cancer. Cancer Res., 1996, 56(12), 2781-2788.
-
(1996)
Cancer Res
, vol.56
, Issue.12
, pp. 2781-2788
-
-
Webster, N.J.1
Resnik, J.L.2
Reichart, D.B.3
Strauss, B.4
Haas, M.5
Seely, B.L.6
-
49
-
-
0029757120
-
Wild-type and mutant p53 differentially regulate transcription of the insulinlike growth factor I receptor gene
-
Werner, H.; Karnieli, E.; Rauscher, F. J.; LeRoith, D. Wild-type and mutant p53 differentially regulate transcription of the insulinlike growth factor I receptor gene. Proc. Natl. Acad Sci. U S A., 1996, 93(16), 8318-8323.
-
(1996)
Proc. Natl. Acad Sci. U S A
, vol.93
, Issue.16
, pp. 8318-8323
-
-
Werner, H.1
Karnieli, E.2
Rauscher, F.J.3
Leroith, D.4
-
50
-
-
33749478922
-
Cancer's molecular sweet tooth and the Warburg effect
-
Kim, J. W.; Dang, C. V. Cancer's molecular sweet tooth and the Warburg effect. Cancer Res., 2006, 66(18), 8927-8930.
-
(2006)
Cancer Res
, vol.66
, Issue.18
, pp. 8927-8930
-
-
Kim, J.W.1
Dang, C.V.2
-
51
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou, I.; Cairns, R. A.; Fontana, L.; Lim, A. L.; Denko, N. C. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab., 2006, 3(3), 187-197.
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
52
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang, H.; Gao, P.; Fukuda, R.; Kumar, G.; Krishnamachary, B.; Zeller, K. I.; Dang, C. V.; Semenza, G. L. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell, 2007, 11(5), 407-420.
-
(2007)
Cancer Cell
, vol.11
, Issue.5
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
Dang, C.V.7
Semenza, G.L.8
-
53
-
-
0032524285
-
P53 inhibits hypoxia-inducible factor-stimulated transcription
-
Blagosklonny, M. V.; An, W. G.; Romanova, L. Y.; Trepel, J.; Fojo, T.; Neckers, L. p53 inhibits hypoxia-inducible factor-stimulated transcription. J. Biol. Chem., 1998, 273(20), 11995-11998.
-
(1998)
J. Biol. Chem
, vol.273
, Issue.20
, pp. 11995-11998
-
-
Blagosklonny, M.V.1
An, W.G.2
Romanova, L.Y.3
Trepel, J.4
Fojo, T.5
Neckers, L.6
-
54
-
-
1842665662
-
Mitochondrial signaling: The retrograde response
-
Butow, R. A.; Avadhani, N. G. Mitochondrial signaling: the retrograde response. Mol. Cell, 2004, 14(1), 1-15.
-
(2004)
Mol. Cell
, vol.14
, Issue.1
, pp. 1-15
-
-
Butow, R.A.1
Avadhani, N.G.2
-
55
-
-
0031717105
-
The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
-
Hardie, D. G.; Carling, D.; Carlson, M. The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu. Rev. Biochem., 1998, 67, 821-855.
-
(1998)
Annu. Rev. Biochem
, vol.67
, pp. 821-855
-
-
Hardie, D.G.1
Carling, D.2
Carlson, M.3
-
56
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones, R. G.; Plas, D. R.; Kubek, S.; Buzzai, M.; Mu, J.; Xu, Y.; Birnbaum, M. J.; Thompson, C. B. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol. Cell, 2005, 18(3), 283-93.
-
(2005)
Mol. Cell
, vol.18
, Issue.3
, pp. 283-293
-
-
Jones, R.G.1
Plas, D.R.2
Kubek, S.3
Buzzai, M.4
Mu, J.5
Xu, Y.6
Birnbaum, M.J.7
Thompson, C.B.8
-
57
-
-
67749089562
-
A hyperfused mitochondrial state achieved at G1-S regulates cyclin
-
Mitra, K.; Wunder, C.; Roysam, B.; Lin, G.; Lippincott-Schwartz, J. A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc. Natl. Acad Sci. USA., 2009, 106(29), 11960-11965.
-
(2009)
E Buildup and Entry Into S Phase. Proc. Natl. Acad Sci. USA
, vol.106
, Issue.29
, pp. 11960-11965
-
-
Mitra, K.1
Wunder, C.2
Roysam, B.3
Lin, G.4
Lippincott-Schwartz, J.5
-
58
-
-
42949152052
-
Activation of AMPactivated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress
-
Okoshi, R.; Ozaki, T.; Yamamoto, H.; Ando, K.; Koida, N.; Ono, S.; Koda, T.; Kamijo, T.; Nakagawara, A.; Kizaki, H. Activation of AMPactivated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress. J. Biol. Chem., 2008, 283(7), 3979-3987.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.7
, pp. 3979-3987
-
-
Okoshi, R.1
Ozaki, T.2
Yamamoto, H.3
Ando, K.4
Koida, N.5
Ono, S.6
Koda, T.7
Kamijo, T.8
Nakagawara, A.9
Kizaki, H.10
-
59
-
-
10344221083
-
Complex III releases superoxide to both sides of the inner mitochondrial membrane
-
Muller, F. L.; Liu, Y.; Van Remmen, H. Complex III releases superoxide to both sides of the inner mitochondrial membrane. J. Biol. Chem., 2004, 279(47), 49064-49073.
-
(2004)
J. Biol. Chem
, vol.279
, Issue.47
, pp. 49064-49073
-
-
Muller, F.L.1
Liu, Y.2
van Remmen, H.3
-
60
-
-
0019073929
-
The metabolic fate of mitochondrial hydrogen peroxide
-
Nohl, H.; Jordan, W. The metabolic fate of mitochondrial hydrogen peroxide. Eur. J. Biochem., 1980, 111(1), 203-210.
-
(1980)
Eur. J. Biochem
, vol.111
, Issue.1
, pp. 203-210
-
-
Nohl, H.1
Jordan, W.2
-
61
-
-
0036889794
-
Nitric oxide inhibition of mitochondrial respiration and its role in cell death
-
Brown, G. C.; Borutaite, V. Nitric oxide inhibition of mitochondrial respiration and its role in cell death. Free Radic. Biol. Med., 2002, 33(11), 1440-1450.
-
(2002)
Free Radic. Biol. Med
, vol.33
, Issue.11
, pp. 1440-1450
-
-
Brown, G.C.1
Borutaite, V.2
-
62
-
-
0035863011
-
Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space
-
Han, D.; Williams, E.; Cadenas, E. Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space. Biochem. J., 2001, 353(Pt 2), 411-416.
-
(2001)
Biochem. J
, vol.353
, Issue.Pt 2
, pp. 411-416
-
-
Han, D.1
Williams, E.2
Cadenas, E.3
-
63
-
-
0029944812
-
Anion channels of the inner membrane of mammalian and yeast mitochondria
-
Ballarin, C.; Sorgato, M. C. Anion channels of the inner membrane of mammalian and yeast mitochondria. J. Bioenerg. Biomembr., 1996, 28(2), 125-130.
-
(1996)
J. Bioenerg. Biomembr
, vol.28
, Issue.2
, pp. 125-130
-
-
Ballarin, C.1
Sorgato, M.C.2
-
64
-
-
0029685882
-
VDAC, a channel in the outer mitochondrial membrane
-
Colombini, M.; Blachly-Dyson, E.; Forte, M. VDAC, a channel in the outer mitochondrial membrane. Ion. Channels., 1996, 4, 169-202.
-
(1996)
Ion. Channels
, vol.4
, pp. 169-202
-
-
Colombini, M.1
Blachly-Dyson, E.2
Forte, M.3
-
65
-
-
0020427486
-
Biology of disease: Free radicals and tissue injury
-
Freeman, B. A.; Crapo, J. D. Biology of disease: free radicals and tissue injury. Lab. Invest., 1982, 47(5), 412-426.
-
(1982)
Lab. Invest
, vol.47
, Issue.5
, pp. 412-426
-
-
Freeman, B.A.1
Crapo, J.D.2
-
66
-
-
0029082812
-
Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism
-
Guidot, D. M.; Repine, J. E.; Kitlowski, A. D.; Flores, S. C.; Nelson, S. K.; Wright, R. M.; McCord, J. M. Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism. J. Clin. Invest., 1995, 96(2), 1131-1136.
-
(1995)
J. Clin. Invest
, vol.96
, Issue.2
, pp. 1131-1136
-
-
Guidot, D.M.1
Repine, J.E.2
Kitlowski, A.D.3
Flores, S.C.4
Nelson, S.K.5
Wright, R.M.6
McCord, J.M.7
-
67
-
-
0027361046
-
Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
-
Hainaut, P.; Milner, J. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res., 1993, 53(19), 4469-4473.
-
(1993)
Cancer Res
, vol.53
, Issue.19
, pp. 4469-4473
-
-
Hainaut, P.1
Milner, J.2
-
68
-
-
0346690271
-
Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells
-
Cobbs, C. S.; Whisenhunt, T. R.; Wesemann, D. R.; Harkins, L. E.; Van Meir, E. G.; Samanta, M. Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells. Cancer Res., 2003, 63(24), 8670-8673.
-
(2003)
Cancer Res
, vol.63
, Issue.24
, pp. 8670-8673
-
-
Cobbs, C.S.1
Whisenhunt, T.R.2
Wesemann, D.R.3
Harkins, L.E.4
van Meir, E.G.5
Samanta, M.6
-
69
-
-
0029013621
-
Role of cysteine residues in regulation of p53 function
-
Rainwater, R.; Parks, D.; Anderson, M. E.; Tegtmeyer, P.; Mann, K. Role of cysteine residues in regulation of p53 function. Mol. Cell Biol., 1995, 15(7), 3892-3903.
-
(1995)
Mol. Cell Biol
, vol.15
, Issue.7
, pp. 3892-3903
-
-
Rainwater, R.1
Parks, D.2
Anderson, M.E.3
Tegtmeyer, P.4
Mann, K.5
-
70
-
-
65349127078
-
Watching the watcher: Regulation of p53 by mitochondria
-
Holley, A. K.; St Clair, D. K. Watching the watcher: regulation of p53 by mitochondria. Future Oncol., 2009, 5(1), 117-130.
-
(2009)
Future Oncol
, vol.5
, Issue.1
, pp. 117-130
-
-
Holley, A.K.1
St. Clair, D.K.2
-
71
-
-
59949097619
-
Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure
-
Nomura, T.; Kamada, R.; Ito, I.; Chuman, Y.; Shimohigashi, Y.; Sakaguchi, K. Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure. Biopolymers, 2009, 91(1), 78-84.
-
(2009)
Biopolymers
, vol.91
, Issue.1
, pp. 78-84
-
-
Nomura, T.1
Kamada, R.2
Ito, I.3
Chuman, Y.4
Shimohigashi, Y.5
Sakaguchi, K.6
-
72
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
Jayaraman, L.; Murthy, K. G.; Zhu, C.; Curran, T.; Xanthoudakis, S.; Prives, C. Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev., 1997, 11(5), 558-570.
-
(1997)
Genes Dev
, vol.11
, Issue.5
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
73
-
-
0033544915
-
Thioredoxin-dependent redox regulation of p53-mediated p21 activation
-
Ueno, M.; Masutani, H.; Arai, R. J.; Yamauchi, A.; Hirota, K.; Sakai, T.; Inamoto, T.; Yamaoka, Y.; Yodoi, J.; Nikaido, T. Thioredoxin-dependent redox regulation of p53-mediated p21 activation. J. Biol. Chem., 1999, 274(50), 35809-35815.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.50
, pp. 35809-35815
-
-
Ueno, M.1
Masutani, H.2
Arai, R.J.3
Yamauchi, A.4
Hirota, K.5
Sakai, T.6
Inamoto, T.7
Yamaoka, Y.8
Yodoi, J.9
Nikaido, T.10
-
74
-
-
0035849784
-
Modulation of p53 dependent gene expression and cell death through thioredoxin-thioredoxin reductase by the Interferon-Retinoid combination
-
Hu, J.; Ma, X.; Lindner, D. J.; Karra, S.; Hofmann, E. R.; Reddy, S. P.; Kalvakolanu, D. V., Modulation of p53 dependent gene expression and cell death through thioredoxin-thioredoxin reductase by the Interferon-Retinoid combination. Oncogene, 2001, 20(31), 4235-4248.
-
(2001)
Oncogene
, vol.20
, Issue.31
, pp. 4235-4248
-
-
Hu, J.1
Ma, X.2
Lindner, D.J.3
Karra, S.4
Hofmann, E.R.5
Reddy, S.P.6
Kalvakolanu, D.V.7
-
75
-
-
20444427605
-
Stressinduced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species
-
Karawajew, L.; Rhein, P.; Czerwony, G.; Ludwig, W. D. Stressinduced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species. Blood, 2005, 105(12), 4767-4775.
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4767-4775
-
-
Karawajew, L.1
Rhein, P.2
Czerwony, G.3
Ludwig, W.D.4
-
76
-
-
0034632669
-
Redox regulation of p53 during hypoxia
-
Chandel, N. S.; Vander Heiden, M. G.; Thompson, C. B.; Schumacker, P. T. Redox regulation of p53 during hypoxia. Oncogene, 2000, 19(34), 3840-3848.
-
(2000)
Oncogene
, vol.19
, Issue.34
, pp. 3840-3848
-
-
Chandel, N.S.1
Vander Heiden, M.G.2
Thompson, C.B.3
Schumacker, P.T.4
-
77
-
-
0029948586
-
Oxidative stress is involved in the UV activation of p53
-
Renzing, J.; Hansen, S.; Lane, D. P. Oxidative stress is involved in the UV activation of p53. J. Cell Sci., 1996, 109 (Pt 5)(1105-1112.
-
(1996)
J. Cell Sci
, vol.109
, Issue.PART. 5
, pp. 1105-1112
-
-
Renzing, J.1
Hansen, S.2
Lane, D.P.3
-
78
-
-
0036294999
-
A role for mitochondria as potential regulators of cellular life span
-
Xu, D.; Finkel, T. A role for mitochondria as potential regulators of cellular life span. Biochem. Biophys. Res. Commun., 2002, 294(2), 245-248.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.294
, Issue.2
, pp. 245-248
-
-
Xu, D.1
Finkel, T.2
-
79
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman, D. The biologic clock: the mitochondria? J. Am. Geriatr Soc., 1972, 20(4), 145-147.
-
(1972)
J. Am. Geriatr Soc
, vol.20
, Issue.4
, pp. 145-147
-
-
Harman, D.1
-
80
-
-
85047695800
-
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
-
Trinei, M.; Giorgio, M.; Cicalese, A.; Barozzi, S.; Ventura, A.; Migliaccio, E.; Milia, E.; Padura, I. M.; Raker, V. A.; Maccarana, M.; Petronilli, V.; Minucci, S.; Bernardi, P.; Lanfrancone, L.; Pelicci, P. G., A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene, 2002, 21(24), 3872-3878.
-
(2002)
Oncogene
, vol.21
, Issue.24
, pp. 3872-3878
-
-
Trinei, M.1
Giorgio, M.2
Cicalese, A.3
Barozzi, S.4
Ventura, A.5
Migliaccio, E.6
Milia, E.7
Padura, I.M.8
Raker, V.A.9
Maccarana, M.10
Petronilli, V.11
Minucci, S.12
Bernardi, P.13
Lanfrancone, L.14
Pelicci, P.G.15
-
81
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio, M.; Migliaccio, E.; Orsini, F.; Paolucci, D.; Moroni, M.; Contursi, C.; Pelliccia, G.; Luzi, L.; Minucci, S.; Marcaccio, M.; Pinton, P.; Rizzuto, R.; Bernardi, P.; Paolucci, F.; Pelicci, P. G., Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell, 2005, 122(2), 221-233.
-
(2005)
Cell
, vol.122
, Issue.2
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
82
-
-
16444382174
-
PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells
-
Liu, Z.; Lu, H.; Shi, H.; Du, Y.; Yu, J.; Gu, S.; Chen, X.; Liu, K. J.; Hu, C. A. PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells. Cancer Res, 2005, 65(5), 1647-1654.
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1647-1654
-
-
Liu, Z.1
Lu, H.2
Shi, H.3
Du, Y.4
Yu, J.5
Gu, S.6
Chen, X.7
Liu, K.J.8
Hu, C.A.9
-
83
-
-
0033229866
-
P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
-
Li, P. F.; Dietz, R.; von Harsdorf, R. p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J., 1999, 18(21), 6027-6036.
-
(1999)
EMBO J
, vol.18
, Issue.21
, pp. 6027-6036
-
-
Li, P.F.1
Dietz, R.2
von Harsdorf, R.3
-
84
-
-
0034775927
-
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
-
Hwang, P. M.; Bunz, F.; Yu, J.; Rago, C.; Chan, T. A.; Murphy, M. P.; Kelso, G. F.; Smith, R. A.; Kinzler, K. W.; Vogelstein, B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nat. Med., 2001, 7(10), 1111-1117.
-
(2001)
Nat. Med
, vol.7
, Issue.10
, pp. 1111-1117
-
-
Hwang, P.M.1
Bunz, F.2
Yu, J.3
Rago, C.4
Chan, T.A.5
Murphy, M.P.6
Kelso, G.F.7
Smith, R.A.8
Kinzler, K.W.9
Vogelstein, B.10
-
85
-
-
0037126392
-
The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis
-
Liu, G.; Chen, X. The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis. Oncogene, 2002, 21(47), 7195-7204.
-
(2002)
Oncogene
, vol.21
, Issue.47
, pp. 7195-7204
-
-
Liu, G.1
Chen, X.2
-
86
-
-
33644542078
-
Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells
-
Zhao, R.; Xiang, N.; Domann, F. E.; Zhong, W. Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells. Cancer Res., 2006, 66(4), 2296-2304.
-
(2006)
Cancer Res
, vol.66
, Issue.4
, pp. 2296-2304
-
-
Zhao, R.1
Xiang, N.2
Domann, F.E.3
Zhong, W.4
-
87
-
-
0036080832
-
Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes
-
Kulisz, A.; Chen, N.; Chandel, N. S.; Shao, Z.; Schumacker, P. T. Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes. Am. J. Physiol. Lung Cell Mol. Physiol., 2002, 282(6), L1324-1329.
-
(2002)
Am. J. Physiol. Lung Cell Mol. Physiol
, vol.282
, Issue.6
-
-
Kulisz, A.1
Chen, N.2
Chandel, N.S.3
Shao, Z.4
Schumacker, P.T.5
-
88
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
-
Bulavin, D. V.; Saito, S.; Hollander, M. C.; Sakaguchi, K.; Anderson, C. W.; Appella, E.; Fornace, A. J. Jr. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J., 1999, 18(23), 6845-6854.
-
(1999)
EMBO J
, vol.18
, Issue.23
, pp. 6845-6854
-
-
Bulavin, D.V.1
Saito, S.2
Hollander, M.C.3
Sakaguchi, K.4
Anderson, C.W.5
Appella, E.6
Fornace Jr., A.J.7
-
89
-
-
57049095435
-
ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes
-
Liu, J.; Mao, W.; Ding, B.; Liang, C. S. ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol., 2008, 295(5), H1956-1965.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol
, vol.295
, Issue.5
-
-
Liu, J.1
Mao, W.2
Ding, B.3
Liang, C.S.4
-
90
-
-
15744376049
-
Involvement of mitogenactivated protein kinases in adriamycin-induced cardiomyopathy
-
Lou, H.; Danelisen, I.; Singal, P. K. Involvement of mitogenactivated protein kinases in adriamycin-induced cardiomyopathy. Am. J. Physiol. Heart Circ. Physiol., 2005, 288(4), H1925-930.
-
(2005)
Am. J. Physiol. Heart Circ. Physiol
, vol.288
, Issue.4
-
-
Lou, H.1
Danelisen, I.2
Singal, P.K.3
-
91
-
-
33744943247
-
Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells
-
Chua, C. C.; Liu, X.; Gao, J.; Hamdy, R. C.; Chua, B. H. Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells. Am. J. Physiol. Heart Circ. Physiol., 2006, 290(6), H2606-2613.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.290
, Issue.6
-
-
Chua, C.C.1
Liu, X.2
Gao, J.3
Hamdy, R.C.4
Chua, B.H.5
-
92
-
-
0141891251
-
Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation
-
Chen, K.; Albano, A.; Ho, A.; Keaney, J. F. Jr. Activation of p53 by oxidative stress involves platelet-derived growth factor-beta receptor-mediated ataxia telangiectasia mutated (ATM) kinase activation. J. Biol. Chem., 2003, 278(41), 39527-39533.
-
(2003)
J. Biol. Chem
, vol.278
, Issue.41
, pp. 39527-39533
-
-
Chen, K.1
Albano, A.2
Ho, A.3
Keaney Jr., J.F.4
-
93
-
-
34250758020
-
H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion
-
Furukawa, A.; Tada-Oikawa, S.; Kawanishi, S.; Oikawa, S. H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion. Cell Physiol. Biochem., 2007, 20(1-4), 45-54.
-
(2007)
Cell Physiol. Biochem
, vol.20
, Issue.1-4
, pp. 45-54
-
-
Furukawa, A.1
Tada-Oikawa, S.2
Kawanishi, S.3
Oikawa, S.4
-
94
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin, S.; Moyal, L.; Shieh, S.; Taya, Y.; Anderson, C. W.; Chessa, L.; Smorodinsky, N. I.; Prives, C.; Reiss, Y.; Shiloh, Y.; Ziv, Y. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science, 1998, 281(5383), 1674-1677.
-
(1998)
Science
, vol.281
, Issue.5383
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
95
-
-
34250375254
-
Mitochondrial and nuclear p53 localization in cardiomyocytes: Redox modulation by doxorubicin (Adriamycin)?
-
Nithipongvanitch, R.; Ittarat, W.; Cole, M. P.; Tangpong, J.; Clair, D. K.; Oberley, T. D. Mitochondrial and nuclear p53 localization in cardiomyocytes: redox modulation by doxorubicin (Adriamycin)? Antioxid Redox Signal, 2007, 9(7), 1001-1008.
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.7
, pp. 1001-1008
-
-
Nithipongvanitch, R.1
Ittarat, W.2
Cole, M.P.3
Tangpong, J.4
Clair, D.K.5
Oberley, T.D.6
-
96
-
-
0031017323
-
Mitochondrial participation in the intracellular Ca2+ network
-
Babcock, D. F.; Herrington, J.; Goodwin, P. C.; Park, Y. B.; Hille, B. Mitochondrial participation in the intracellular Ca2+ network. J. Cell Biol., 1997, 136(4), 833-844.
-
(1997)
J. Cell Biol
, vol.136
, Issue.4
, pp. 833-844
-
-
Babcock, D.F.1
Herrington, J.2
Goodwin, P.C.3
Park, Y.B.4
Hille, B.5
-
97
-
-
0037038669
-
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
-
Amuthan, G.; Biswas, G.; Ananadatheerthavarada, H. K.; Vijayasarathy, C.; Shephard, H. M.; Avadhani, N. G. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene, 2002, 21(51), 7839-7849.
-
(2002)
Oncogene
, vol.21
, Issue.51
, pp. 7839-7849
-
-
Amuthan, G.1
Biswas, G.2
Ananadatheerthavarada, H.K.3
Vijayasarathy, C.4
Shephard, H.M.5
Avadhani, N.G.6
-
98
-
-
0037080987
-
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
-
Arnould, T.; Vankoningsloo, S.; Renard, P.; Houbion, A.; Ninane, N.; Demazy, C.; Remacle, J.; Raes, M. CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. EMBO J., 2002, 21(1-2), 53-63.
-
(2002)
EMBO J
, vol.21
, Issue.1-2
, pp. 53-63
-
-
Arnould, T.1
Vankoningsloo, S.2
Renard, P.3
Houbion, A.4
Ninane, N.5
Demazy, C.6
Remacle, J.7
Raes, M.8
-
99
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko, N. D.; Zaika, A.; Moll, U. M. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J. Biol. Chem., 2000, 275(21), 16202-16212.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.21
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
100
-
-
72549085096
-
Transcription-independent p53 apoptosis: An alternative route to death
-
Speidel, D. Transcription-independent p53 apoptosis: an alternative route to death. Trends Cell Biol., 2009, 20(1), 14-24.
-
(2009)
Trends Cell Biol
, vol.20
, Issue.1
, pp. 14-24
-
-
Speidel, D.1
-
101
-
-
77649190277
-
Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer
-
Ahn, B. Y.; Trinh, D. L.; Zajchowski, L. D.; Lee, B.; Elwi, A. N.; Kim, S. W. Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer. Oncogene, 2010, 29(8), 1155-1166.
-
(2010)
Oncogene
, vol.29
, Issue.8
, pp. 1155-1166
-
-
Ahn, B.Y.1
Trinh, D.L.2
Zajchowski, L.D.3
Lee, B.4
Elwi, A.N.5
Kim, S.W.6
-
102
-
-
33847276654
-
Monoubiquitylation promotes mitochondrial p53 translocation
-
Marchenko, N. D.; Wolff, S.; Erster, S.; Becker, K.; Moll, U. M. Monoubiquitylation promotes mitochondrial p53 translocation. EMBO J., 2007, 26(4), 923-934.
-
(2007)
EMBO J
, vol.26
, Issue.4
, pp. 923-934
-
-
Marchenko, N.D.1
Wolff, S.2
Erster, S.3
Becker, K.4
Moll, U.M.5
-
103
-
-
53149085250
-
Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease
-
Boopathi, E.; Srinivasan, S.; Fang, J. K.; Avadhani, N. G. Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease. Mol. Cell, 2008, 32(1), 32-42.
-
(2008)
Mol. Cell
, vol.32
, Issue.1
, pp. 32-42
-
-
Boopathi, E.1
Srinivasan, S.2
Fang, J.K.3
Avadhani, N.G.4
-
104
-
-
67650501132
-
MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway
-
Mancini, F.; Di Conza, G.; Pellegrino, M.; Rinaldo, C.; Prodosmo, A.; Giglio, S.; D'Agnano, I.; Florenzano, F.; Felicioni, L.; Buttitta, F.; Marchetti, A.; Sacchi, A.; Pontecorvi, A.; Soddu, S.; Moretti, F. MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway. EMBO J., 2009, 28(13), 1926-1939.
-
(2009)
EMBO J
, vol.28
, Issue.13
, pp. 1926-1939
-
-
Mancini, F.1
Di Conza, G.2
Pellegrino, M.3
Rinaldo, C.4
Prodosmo, A.5
Giglio, S.6
D'agnano, I.7
Florenzano, F.8
Felicioni, L.9
Buttitta, F.10
Marchetti, A.11
Sacchi, A.12
Pontecorvi, A.13
Soddu, S.14
Moretti, F.15
-
105
-
-
41449100068
-
Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion
-
Liu, J.; St Clair, D. K.; Gu, X.; Zhao, Y. Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion. FEBS Lett., 2008, 582(9), 1319-1324.
-
(2008)
FEBS Lett
, vol.582
, Issue.9
, pp. 1319-1324
-
-
Liu, J.1
St. Clair, D.K.2
Gu, X.3
Zhao, Y.4
-
106
-
-
67651174517
-
P53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress
-
Ventura, N.; Rea, S. L.; Schiavi, A.; Torgovnick, A.; Testi, R.; Johnson, T. E. p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. Aging Cell, 2009, 8(4), 380-393.
-
(2009)
Aging Cell
, vol.8
, Issue.4
, pp. 380-393
-
-
Ventura, N.1
Rea, S.L.2
Schiavi, A.3
Torgovnick, A.4
Testi, R.5
Johnson, T.E.6
-
107
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden, K. H.; Lu, X. Live or let die: the cell's response to p53. Nat. Rev. Cancer, 2002, 2(8), 594-604.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.8
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
108
-
-
0036606407
-
Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277
-
Buzek, J.; Latonen, L.; Kurki, S.; Peltonen, K.; Laiho, M. Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277. Nucleic Acids Res., 2002, 30(11), 2340-2348.
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.11
, pp. 2340-2348
-
-
Buzek, J.1
Latonen, L.2
Kurki, S.3
Peltonen, K.4
Laiho, M.5
-
109
-
-
0242552555
-
Influence of induced reactive oxygen species in p53-mediated cell fate decisions
-
Macip, S.; Igarashi, M.; Berggren, P.; Yu, J.; Lee, S. W.; Aaronson, S. A. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Mol. Cell Biol., 2003, 23(23), 8576-8585.
-
(2003)
Mol. Cell Biol
, vol.23
, Issue.23
, pp. 8576-8585
-
-
Macip, S.1
Igarashi, M.2
Berggren, P.3
Yu, J.4
Lee, S.W.5
Aaronson, S.A.6
-
110
-
-
0031940986
-
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
-
Melov, S.; Schneider, J. A.; Day, B. J.; Hinerfeld, D.; Coskun, P.; Mirra, S. S.; Crapo, J. D.; Wallace, D. C. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nat. Genet., 1998, 18(2), 159-163.
-
(1998)
Nat. Genet
, vol.18
, Issue.2
, pp. 159-163
-
-
Melov, S.1
Schneider, J.A.2
Day, B.J.3
Hinerfeld, D.4
Coskun, P.5
Mirra, S.S.6
Crapo, J.D.7
Wallace, D.C.8
-
111
-
-
0031035767
-
Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase
-
Zhong, W.; Oberley, L. W.; Oberley, T. D.; Clair, St D. K. Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase. Oncogene, 1997, 14(4), 481-490.
-
(1997)
Oncogene
, vol.14
, Issue.4
, pp. 481-490
-
-
Zhong, W.1
Oberley, L.W.2
Oberley, T.D.3
St. Clair, D.K.4
-
112
-
-
0035945676
-
Reciprocal downregulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis
-
Drane, P.; Bravard, A.; Bouvard, V.; May, E. Reciprocal downregulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis. Oncogene, 2001, 20(4), 430-439.
-
(2001)
Oncogene
, vol.20
, Issue.4
, pp. 430-439
-
-
Drane, P.1
Bravard, A.2
Bouvard, V.3
May, E.4
-
113
-
-
33746819118
-
Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression
-
Dhar, S. K.; Xu, Y.; Chen, Y.; Clair, St D. K. Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression. J. Biol. Chem., 2006, 281(31), 21698-21709.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.31
, pp. 21698-21709
-
-
Dhar, S.K.1
Xu, Y.2
Chen, Y.3
St. Clair, D.K.4
-
114
-
-
77951219693
-
Nuclear factor kappa-B-and specificity protein 1-dependent p53-mediated bi-directional regulation of the human manganese superoxide dismutase gene
-
Jan 8, Epub
-
Dhar, S. K.; Xu, Y.; Clair, St D. K. Nuclear factor kappa-B-and specificity protein 1-dependent p53-mediated bi-directional regulation of the human manganese superoxide dismutase gene. J. Biol. Chem., 2010, Jan 8, Epub.
-
(2010)
J. Biol. Chem
-
-
Dhar, S.K.1
Xu, Y.2
St. Clair, D.K.3
-
115
-
-
18144382261
-
P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase
-
Zhao, Y.; Chaiswing, L.; Velez, J. M.; Batinic-Haberle, I.; Colburn, N. H.; Oberley, T. D.; Clair, St D. K. p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. Cancer Res., 2005, 65(9), 3745-3750.
-
(2005)
Cancer Res
, vol.65
, Issue.9
, pp. 3745-3750
-
-
Zhao, Y.1
Chaiswing, L.2
Velez, J.M.3
Batinic-Haberle, I.4
Colburn, N.H.5
Oberley, T.D.6
St. Clair, D.K.7
-
116
-
-
4344566202
-
Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells
-
Mahyar-Roemer, M.; Fritzsche, C.; Wagner, S.; Laue, M.; Roemer, K. Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells. Oncogene, 2004, 23(37), 6226-6236.
-
(2004)
Oncogene
, vol.23
, Issue.37
, pp. 6226-6236
-
-
Mahyar-Roemer, M.1
Fritzsche, C.2
Wagner, S.3
Laue, M.4
Roemer, K.5
-
117
-
-
0030604728
-
P53 Protein exhibits 3'-to-5' exonuclease activity
-
Mummenbrauer, T.; Janus, F.; Muller, B.; Wiesmuller, L.; Deppert, W.; Grosse, F. p53 Protein exhibits 3'-to-5' exonuclease activity. Cell, 1996, 85(7), 1089-1099.
-
(1996)
Cell
, vol.85
, Issue.7
, pp. 1089-1099
-
-
Mummenbrauer, T.1
Janus, F.2
Muller, B.3
Wiesmuller, L.4
Deppert, W.5
Grosse, F.6
-
118
-
-
0037448658
-
P53-associated 3'-->5' exonuclease activity in nuclear and cytoplasmic compartments of cells
-
Lilling, G.; Elena, N.; Sidi, Y.; Bakhanashvili, M. p53-associated 3'-->5' exonuclease activity in nuclear and cytoplasmic compartments of cells. Oncogene, 2003, 22(2), 233-245.
-
(2003)
Oncogene
, vol.22
, Issue.2
, pp. 233-245
-
-
Lilling, G.1
Elena, N.2
Sidi, Y.3
Bakhanashvili, M.4
-
119
-
-
56349167583
-
P53 in mitochondria enhances the accuracy of DNA synthesis
-
Bakhanashvili, M.; Grinberg, S.; Bonda, E.; Simon, A. J.; Moshitch-Moshkovitz, S.; Rahav, G. p53 in mitochondria enhances the accuracy of DNA synthesis. Cell Death Differ., 2008, 15(12), 1865-1874.
-
(2008)
Cell Death Differ
, vol.15
, Issue.12
, pp. 1865-1874
-
-
Bakhanashvili, M.1
Grinberg, S.2
Bonda, E.3
Simon, A.J.4
Moshitch-Moshkovitz, S.5
Rahav, G.6
-
120
-
-
4444323263
-
P53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria
-
de Souza-Pinto, N. C.; Harris, C. C.; Bohr, V. A. p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria. Oncogene, 2004, 23(39), 6559-6568.
-
(2004)
Oncogene
, vol.23
, Issue.39
, pp. 6559-6568
-
-
de Souza-Pinto, N.C.1
Harris, C.C.2
Bohr, V.A.3
-
121
-
-
0038418297
-
P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA
-
Yoshida, Y.; Izumi, H.; Torigoe, T.; Ishiguchi, H.; Itoh, H.; Kang, D.; Kohno, K. P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA. Cancer Res., 2003, 63(13), 3729-3734.
-
(2003)
Cancer Res
, vol.63
, Issue.13
, pp. 3729-3734
-
-
Yoshida, Y.1
Izumi, H.2
Torigoe, T.3
Ishiguchi, H.4
Itoh, H.5
Kang, D.6
Kohno, K.7
-
122
-
-
59749094729
-
Physical and functional interactions between human mitochondrial single-stranded DNAbinding protein and tumour suppressor p53
-
Wong, T. S.; Rajagopalan, S.; Townsley, F. M.; Freund, S. M.; Petrovich, M.; Loakes, D.; Fersht, A. R. Physical and functional interactions between human mitochondrial single-stranded DNAbinding protein and tumour suppressor p53. Nucleic Acids Res., 2009, 37(2), 568-581.
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.2
, pp. 568-581
-
-
Wong, T.S.1
Rajagopalan, S.2
Townsley, F.M.3
Freund, S.M.4
Petrovich, M.5
Loakes, D.6
Fersht, A.R.7
-
123
-
-
34249029995
-
Evidence for p53 as guardian of the cardiomyocyte mitochondrial genome following acute adriamycin treatment
-
Nithipongvanitch, R.; Ittarat, W.; Velez, J. M.; Zhao, R.; Clair, St D. K.; Oberley, T. D. Evidence for p53 as guardian of the cardiomyocyte mitochondrial genome following acute adriamycin treatment. J. Histochem. Cytochem., 2007, 55(6), 629-639.
-
(2007)
J. Histochem. Cytochem
, vol.55
, Issue.6
, pp. 629-639
-
-
Nithipongvanitch, R.1
Ittarat, W.2
Velez, J.M.3
Zhao, R.4
St. Clair, D.K.5
Oberley, T.D.6
-
124
-
-
68549083716
-
Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents
-
Kienhofer, J.; Haussler, D. J.; Ruckelshausen, F.; Muessig, E.; Weber, K.; Pimentel, D.; Ullrich, V.; Burkle, A.; Bachschmid, M. M. Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J., 2009, 23(7), 2034-2044.
-
(2009)
FASEB J
, vol.23
, Issue.7
, pp. 2034-2044
-
-
Kienhofer, J.1
Haussler, D.J.2
Ruckelshausen, F.3
Muessig, E.4
Weber, K.5
Pimentel, D.6
Ullrich, V.7
Burkle, A.8
Bachschmid, M.M.9
-
125
-
-
38949203787
-
Is mitochondrial generation of reactive oxygen species a trigger for autophagy?
-
Chen, Y.; Gibson, S. B. Is mitochondrial generation of reactive oxygen species a trigger for autophagy? Autophagy, 2008, 4(2), 246-248.
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 246-248
-
-
Chen, Y.1
Gibson, S.B.2
-
126
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval, R.; Shvets, E.; Fass, E.; Shorer, H.; Gil, L.; Elazar, Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J., 2007, 26(7), 1749-1760.
-
(2007)
EMBO J
, vol.26
, Issue.7
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
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