Oxidative stress is involved in the UV activation of p53

Journal of Cell Science

Volumn 109, Issue 5, 1996, Pages 1105-1112

  Renzing, Jochen ^a   Hansen, Silke ^a   Lane, David P ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

DNA damage; Ionizing radiation; N acetylcysteine; Oxidative stress; p53; UV C

Indexed keywords

ACETYLCYSTEINE; DNA; PROTEIN P53;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; GENE INDUCTION; IONIZING RADIATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; RADIATION INJURY; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

3T3 CELLS; ACETYLCYSTEINE; ANIMALS; BASE SEQUENCE; CELL LINE; DNA DAMAGE; FIBROBLASTS; G1 PHASE; MICE; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; RADIATION TOLERANCE; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

ANIMALIA; VERTEBRATA;

EID: 0029948586     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Bargonetti, J., Friedman, P. N., Kern, S. E., Vogelstein, B. and Prives, C. (1991). Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell 65, 1083-1091.
2. Bose, B., Agarwal, S. and Chatterjee, S. N. (1990). Membrane lipid peroxidation by UV-A: mechanism and implications. Biotechnol. Appl. Biochem. 12, 557-561.
3. Chowdary, D. R., Dermody, J. J., Jha, K. K. and Ozer, H. L. (1994). Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway. Mol. Cell Biol. 14, 1997-2003.
4. Devary, Y., Gottlieb, R. A., Smeal, T. and Karin, M. (1992). The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71, 1081-1091.
5. el Deiry, W., Kern, S. E., Pietenpol, J. A., Kinzler, K. W. and Vogelstein, B. (1992). Definition of a consensus binding site for p53. Nature Genet. 1, 45-49.
6. Ewing, D. (1991). Can ·OH scavengers protect against direct UV-C damage in vivo? Int. J. Radiat. Biol. 60, 449-452.
7. Farmer, G., Bargonetti, J., Zhu, H., Friedman, P., Prywes, R. and Prives, C. (1992). Wild-type p53 activates transcription in vitro [see comments]. Nature 358, 83-86.
8. Fornace, J. A. J. (1982). Measurement of M. Luteus endonuclease-sensitive lesions by alkaline elution. Mutat. Res. 94, 263-276.
9. Frebourg, T., Barbier, N., Kassel, J., Ng, Y. S., Romero, P. and Friend, S. H. (1992). A functional screen for germ line p53 mutations based on transcriptional activation. Cancer Res. 52, 6976-6978.
10. Fritsche, M., Haessler, C. and Brandner, G. (1993). Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8, 307-318.
11. Gedik, C. M., Ewen, S. W. and Collins, A. R. (1992). Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells. Int. J. Radiat. Biol. 62, 313-320.
12. Ghosh, R., Amstrad, P. and Cerutti, P. (1993). UVB-induced DNA breaks interfere with transcriptional induction of c-fos. Mol. Cell. Biol. 13, 6992-6999.
13. 1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol. Cell Biol 14, 6264-6277.
14. Halazonetis and Kandil, A. N. (1993). Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding to select p53 mutants. EMBO J. 12, 5057-5064.
15. Hall, P. A., McKee, P. H., Menage, H. D., Dover, R. and Lane, D. P. (1993). High levels of p53 protein in UV-irradiated normal human skin. Oncogene 8, 203-207.
16. Hansen, S., Hupp, T. R. and Lane, D. P. (1996). Allosteric regulation of the thermo-stability and DNA binding activity of human p53 by specific interacting proteins. J. Biol. Chem. 271, 3917-3924.
17. Herrlich, P., Sachsenmaier, C., Radler, P. A., Gebel, S., Blattner, C. and Rahmsdorf, H. J. (1994). The mammalian UV response: mechanism of DNA damage induced gene expression. Advan. Enzyme Regul. 34, 381-395.
18. Huang, R. P. and Adamson, E. D. (1995). A biological role for Egr-1 in cell survival following ultra-violet irradiation. Oncogene 10, 467-475.
19. Hupp, T. R., Meek, D. W., Midgley, C. A. and Lane, D. P. (1992). Regulation of the specific DNA binding function of p53. Cell 71, 875-86.
20. Hupp, T. R. and Lane, D. P. (1994). Allosteric activation of latent p53 tetramers. Curr. Biol. 4, 865-875.
21. Hupp, T. R., Sparks, A. and Lane, D. P. (1995). Small peptides activate the latent DNA binding function of p53. Cell 83, 237-245.
22. Jackson, D. A., Hassan, A. B., Errington, R. J. and Cook, P. R. (1994) Sites in human nuclei where damage induced by ultraviolet light is repaired: localization relative to transcription sites and concentrations of proliferating cell nuclear antigen and the tumour suppressor protein, p53. J. Cell Sci. 107, 1753-1760.
23. Jurkiewicz, B. A. and Buettner, G. R. (1994). Ultraviolet light-induced free radical formation in skin: an electron paramagnetic resonance study. Photochem. Photobiol. 59, 1-4.
24. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. and Craig, R. W. (1991). Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51, 6304-6311.
25. Kikugawa, K., Hiramoto, K., Okamoto, Y. and Hasegawa, Y. K. (1994). Enhancement of nitrogen dioxide-induced lipid peroxidation and DNA strand breaking by cysteine and glutathione. Free Radical Res. 21, 399-408.
26. Konishi, T., Kagan, V., Matsugo, S. and Packer, L. (1991). UV induces oxy-and chromanoxyl free radicals in microsomes by a new photosensitive organic hydroperoxide, N,N′-bis(2-hydroperoxy-2-methoxyethyl)- 1,4,5,8-naphtalene-tetra-carboxylic-diimide. Biochem. Biophys Res. Commun. 175, 129-133.
27. Lane, D. P. (1992). p53, guardian of the genome. Nature 358, 15-16.
28. Lu, X. and Lane, D. P. (1993). Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell 75, 765-778.
29. Maltzman, W. and Czyzyk, L. (1984). UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol. Cell Biol. 4, 1689-1694.
30. Meister, A. (1991). Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol. Ther. 51, 155-194.
31. Messmer, U. K., Ankarcrona, M., Nicotera, P. and Brune, B. (1994). p53 expression in nitric oxide-induced apoptosis. FEBS Lett. 355, 23-26.
32. Milne, D. M., Campbell, L. E., Campbell, D. G. and Meek, D. W. (1995). p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J. Biol. Chem. 270, 5511-5518.
33. Molinari, M. and Milner, J. (1995). p53 in complex with DNA is resistant to ubiquitin-dependent proteolysis in the presence of HPV-16 E6. Oncogene 10, 1849-1854.
34. Mosner, J., Mummenbrauer, T., Bauer, C., Sczakiel, G., Grosse, F. and Deppert, W. (1995). Negative feedback regulation of wild-type p53 biosynthesis. EMBO J. 14, 4442-4449.
35. Muramatsu, T., Tada, H., Kobayashi, N., Yamji, M., Shirai, T. and Ohnishi, T. (1992). Induction of the 72-kD heat shock protein in organ-cultured normal human skin. J. Invest. Dermatol. 98, 786-790.
36. Nelson, W. G. and Kastan, M. B. (1994). DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell Biol. 14, 1815-1823.
37. Ogura, R., Sugiyama, M., Nishi, J. and Haramaki, N. (1991). Mechanism of lipid radical formation following exposure of epidermal homogenate to ultraviolet light. J. Invest. Dermatol. 97, 1044-1047.
38. Oren, M., Maltzman, W. and Levine, A. J. (1981). Post-translational regulation of the 54k cellular tumor antigen in normal and transformed cells. Mol. Cell Biol. 1, 101-110.
39. Peak, J. G. and Peak, M. J. (1991). Comparison of initial yields of DNA-to-protein crosslinks and single-strand breaks induced in cultured human cells by far- and near-ultraviolet light, blue light and X-rays. Mutat. Res. 246, 187-191.
40. Pinhasi, K. O., Michalovitz, D., Ben, Z. A. and Oren, M. (1986). Specific interaction between the p53 cellular tumour antigen and major heat shock proteins. Nature 320, 182-184.
41. Plumb, M., Frampton, J., Wainwright, H., Walker, M., Macleod, K., Goodwin, G. and Harrison, P. (1989). GATAAG; a cis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression. Nucl. Acids Res. 17, 73-92.
42. Renzing, J. and Lane, D. (1995). p53-dependent growth arrest following calcium phosphate-mediated transfection of murine fibroblasts. Oncogene 10, 1865-1868.
43. Santoro, C., Mermod, N., Andrews, P. C. and Tjian, R. (1988). A family of human CCAAT-box-binding proteins active in transcription and DNA-replication - cloning and expression of multiple cDNAs. Nature 334, 218-224.
44. Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J. and Howley, P. M. (1990). The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63, 1129-1136.
45. Schreck, R., Albermann, K. and Baeuerle, P. A. (1992). Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radical Res. Commun. 17, 221-237.
46. Schreiber, E., Matthias, P., Müller, M. M. and Schaffner, W. (1989). Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucl. Acids Res. 17, 6419.
47. Schwartz, J. L., Antoniades, D. Z. and Zhao, S. (1993). Molecular and biochemical reprogramming of oncogenesis through the activity of prooxidants and antioxidants. Ann NY Acad. Sci. 686, 262-278 (discussion 278-279).
48. Sgonc, R., Boeck, G., Dietrich, H., Gruber, J., Recheis, H. and Wick, G. (1994). Simultaneous determination of cell surface antigens and apoptosis. Trends Genet. 10, 41-42.
49. Sturzbecher, H. W., Addison, C. and Jenkins, J. R. (1988). Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells. Mol. Cell Biol. 8, 3740-3747.
50. Sun, X., Shimizu, H. and Yamamoto, K. I. (1995). Identification of a novel p53 promotor element involved in genotoxic stress-inducible p53 gene expression. Mol. Cell Biol. 15, 4489-4496.
51. Suzuki, K. and Watanabe, M. (1992). Augmented expression of HSP72 protein in normal human fibroblasts irradiated with ultraviolet light. Biochem. Biophys. Res. Commun. 186, 1257-1264.
52. Vaughan, A. T. M., Gordon, D. J., Grdina, D. J. and Milner, A. E. (1990). Analysis of radiation and chemical damage in mammalian cells. In Flow Cytometry (ed. M. G. Ormerod). IRL Press, Oxford, New York, Tokyo.
53. Yewdell, J. W., Gannon, J. V. and Lane, D. P. (1986). Monoclonal antibody analysis of p53 expression in normal and transformed cells. J. Virol. 59, 444-452.
54. Yonish Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A. and Oren, M. (1991). Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352, 345-347.
55. Zhan, Q., Carrier, F. and Fornace, A. J. Jr (1993). Induction of cellular p53 activity by DNA-damaging agents and growth arrest [published erratum appears in Mol. Cell Biol. (1993) 13, 5928]. Mol. Cell Biol. 13, 4242-4250.