메뉴 건너뛰기




Volumn 4, Issue 1, 2013, Pages

Immunoexcitatory mechanisms in glioma proliferation, invasion and occasional metastasis

Author keywords

Glioblastoma; immunoexcitotoxicity; inflammatory cytokines; metastasis; tumor invasion

Indexed keywords

AMPA RECEPTOR; CALCIUM ION; CURCUMIN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; QUERCETIN; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875181212     PISSN: None     EISSN: 21527806     Source Type: Journal    
DOI: 10.4103/2152-7806.106577     Document Type: Review
Times cited : (14)

References (130)
  • 1
    • 58149340584 scopus 로고    scopus 로고
    • The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas
    • Abou-Ghazal M, Yang DS, Qiao W, Reina-Ortiz C, Wei J, Kong LY, et al. The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas. Clin Cancer Res 2008;14:8228-35.
    • (2008) Clin Cancer Res , vol.14 , pp. 8228-8235
    • Abou-Ghazal, M.1    Yang, D.S.2    Qiao, W.3    Reina-Ortiz, C.4    Wei, J.5    Kong, L.Y.6
  • 2
    • 0037097249 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and cyclooxygenase-2 after excitotoxic damage to the immature rat brain
    • Acarin L, Peluffo H, Gonsalez B, Castellano B. Expression of inducible nitric oxide synthase and cyclooxygenase-2 after excitotoxic damage to the immature rat brain. J Neurosci Res 2002;68:745-54.
    • (2002) J Neurosci Res , vol.68 , pp. 745-754
    • Acarin, L.1    Peluffo, H.2    Gonsalez, B.3    Castellano, B.4
  • 3
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal BB. Nuclear factor-kappaB: The enemy within. Cancer Cell 2004;6:203-8.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 4
    • 0033579163 scopus 로고    scopus 로고
    • Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity
    • Ali IU, Schriml LM, Dean M. Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 1999;91:1922-32.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1922-1932
    • Ali, I.U.1    Schriml, L.M.2    Dean, M.3
  • 5
    • 34347238938 scopus 로고    scopus 로고
    • Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways
    • Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol 2007;72:29-39.
    • (2007) Mol Pharmacol , vol.72 , pp. 29-39
    • Aoki, H.1    Takada, Y.2    Kondo, S.3    Sawaya, R.4    Aggarwal, B.B.5    Kondo, Y.6
  • 6
    • 0037118575 scopus 로고    scopus 로고
    • Akt2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
    • Bacus SS, Altomare DA, Lyass L, Chin DM, Farrell MP, Gurova K, et al. Akt2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival. Oncogene 2002;21:3532-40.
    • (2002) Oncogene , vol.21 , pp. 3532-3540
    • Bacus, S.S.1    Altomare, D.A.2    Lyass, L.3    Chin, D.M.4    Farrell, M.P.5    Gurova, K.6
  • 7
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, Mclendon RE, Hao Y, Shi Q, Hielmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756-60.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hielmeland, A.B.6
  • 9
    • 22544483518 scopus 로고    scopus 로고
    • Modular effects of interleukin-1beta and tumor necrosis factor-Alpha on AMPA-induced excitotoxicity in mouse organotypic slice cultures
    • Bernadino L, Xapelli S, Silva AP, Jakobsen B, Poulsen FR, Oliverira CR, et al. Modular effects of interleukin-1beta and tumor necrosis factor-Alpha on AMPA-induced excitotoxicity in mouse organotypic slice cultures. J Neurosci 2005;25:6734-44.
    • (2005) J Neurosci , vol.25 , pp. 6734-6744
    • Bernadino, L.1    Xapelli, S.2    Silva, A.P.3    Jakobsen, B.4    Poulsen, F.R.5    Oliverira, C.R.6
  • 10
    • 34247848682 scopus 로고    scopus 로고
    • Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival
    • Bian XW, Yang SX, Chen JH, Ping YF, Zhou XD, Wang QL, et al. Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival. Neurosurgery 2007;61:570-8.
    • (2007) Neurosurgery , vol.61 , pp. 570-578
    • Bian, X.W.1    Yang, S.X.2    Chen, J.H.3    Ping, Y.F.4    Zhou, X.D.5    Wang, Q.L.6
  • 12
    • 82955171270 scopus 로고    scopus 로고
    • Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis
    • Blaylock R, Maroon J. Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis. Surg Neurol Int 2011;2:107.
    • (2011) Surg Neurol Int , vol.2 , pp. 107
    • Blaylock, R.1    Maroon, J.2
  • 14
    • 77954317769 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis and excitotoxicity: From pathological mechanism to therapeutic target
    • Bogaert E, d'Ydewalle C, Van Den Bosch L. Amyotrophic lateral sclerosis and excitotoxicity: From pathological mechanism to therapeutic target. CNS Neurol Disord Drug Targets 2010;9:297-304.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 297-304
    • Bogaert, E.1    D'Ydewalle, C.2    Van Den Bosch, L.3
  • 16
    • 28544453276 scopus 로고    scopus 로고
    • Prognostic and clinical implications of IL-6 expression in glioblastoma multiforme
    • Chang CY, Li MC, Liao SL, Huang YL, Shen CC, Pan HC. Prognostic and clinical implications of IL-6 expression in glioblastoma multiforme. J Clin Neurosci 2005;12:930-3.
    • (2005) J Clin Neurosci , vol.12 , pp. 930-933
    • Chang, C.Y.1    Li, M.C.2    Liao, S.L.3    Huang, Y.L.4    Shen, C.C.5    Pan, H.C.6
  • 17
    • 18244393785 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance
    • Chang HJ, Yoo BC, Lim SB, Jeong SY, Kim WH, Park JG. Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance. Clin Cancer Res 2005;11:3288-95.
    • (2005) Clin Cancer Res , vol.11 , pp. 3288-3295
    • Chang, H.J.1    Yoo, B.C.2    Lim, S.B.3    Jeong, S.Y.4    Kim, W.H.5    Park, J.G.6
  • 18
    • 0028577356 scopus 로고
    • Tumor necrosis factor-Alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
    • Chao CC, Hu S. Tumor necrosis factor-Alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev Neurosci 1994;16:172-9.
    • (1994) Dev Neurosci , vol.16 , pp. 172-179
    • Chao, C.C.1    Hu, S.2
  • 19
    • 22144488038 scopus 로고    scopus 로고
    • Proinflammatory cytokines and apoptsis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats
    • Chaparro-Huerta V, Rivera-Cervantes MC, Flores-Soto ME, Gomez-Pinedo U, Beas-Zarate C. Proinflammatory cytokines and apoptsis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats. J Neuroimmunol 2005;165:53-62.
    • (2005) J Neuroimmunol , vol.165 , pp. 53-62
    • Chaparro-Huerta, V.1    Rivera-Cervantes, M.C.2    Flores-Soto, M.E.3    Gomez-Pinedo, U.4    Beas-Zarate, C.5
  • 20
    • 36849021582 scopus 로고    scopus 로고
    • Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF Kappa B pathway
    • Choi BH, Kim CG, Lim Y, Shin SY, Lee YH. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF Kappa B pathway. Cancer Lett 2008;259:111-8.
    • (2008) Cancer Lett , vol.259 , pp. 111-118
    • Choi, B.H.1    Kim, C.G.2    Lim, Y.3    Shin, S.Y.4    Lee, Y.H.5
  • 21
    • 80053073264 scopus 로고    scopus 로고
    • Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice
    • Choi KY, Chang K, Pickel JM, Badger JD 2nd, Roche KW. Expression of the metabotropic glutamate receptor 5 (mGluR5) induces melanoma in transgenic mice. Proc Natl Acad Sci USA 2011;108:15219-24.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 15219-15224
    • Choi, K.Y.1    Chang, K.2    Pickel, J.M.3    Badger II, J.D.4    Roche, K.W.5
  • 23
  • 25
    • 84866181541 scopus 로고    scopus 로고
    • Hypoxia control to normalize pathologic angiogenesis: Potential role for endothelial precursor cells and miRNAs regulation
    • Collet G, Skrzypek K, Grillion C, Matejuk A, El Hafni-Rahbi B, Lamerant-Favel N, et al. Hypoxia control to normalize pathologic angiogenesis: Potential role for endothelial precursor cells and miRNAs regulation. Vascul Pharmacol 2012;56:252-61.
    • (2012) Vascul Pharmacol , vol.56 , pp. 252-261
    • Collet, G.1    Skrzypek, K.2    Grillion, C.3    Matejuk, A.4    El Hafni-Rahbi, B.5    Lamerant-Favel, N.6
  • 26
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability. Carcinogenesis 2009;30:1073-81.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 27
    • 40849120593 scopus 로고    scopus 로고
    • Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
    • Cortesio CL, Chan KT, Perrin BJ, Burton NO, Zhang S, Zhang ZY, et al. Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. J Cell Biol 2008;180:957-71.
    • (2008) J Cell Biol , vol.180 , pp. 957-971
    • Cortesio, C.L.1    Chan, K.T.2    Perrin, B.J.3    Burton, N.O.4    Zhang, S.5    Zhang, Z.Y.6
  • 28
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z Inflammation and cancer. Nature 2002;420:860-7.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 29
    • 0035911230 scopus 로고    scopus 로고
    • Inflammatory cells and cancer: Think different!
    • Coussens LM, Werb Z Inflammatory cells and cancer: Think different! J Exp Med 2001;193:F23-6.
    • (2001) J Exp Med , vol.193
    • Coussens, L.M.1    Werb, Z.2
  • 30
    • 43149104379 scopus 로고    scopus 로고
    • Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation
    • de Groot JF, Piao Y, Lu L, Fuller GN, Yung WK. Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation. J Neurooncol 2008;88:121-33.
    • (2008) J Neurooncol , vol.88 , pp. 121-133
    • De Groot, J.F.1    Piao, Y.2    Lu, L.3    Fuller, G.N.4    Yung, W.K.5
  • 31
    • 0038312031 scopus 로고    scopus 로고
    • Calcium-permeable AMPA/kainite receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors
    • Deng W, Rosenberg PA, Volpe JJ, Jensen FE. Calcium-permeable AMPA/kainite receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. Proc Natl Acad Sci USA 2003;100:6801-6.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6801-6806
    • Deng, W.1    Rosenberg, P.A.2    Volpe, J.J.3    Jensen, F.E.4
  • 33
    • 58149314184 scopus 로고    scopus 로고
    • CXCR4 mediates the proliferation of glioblastoma progenitor cells
    • Ehtesham M, Mapara KY, Stevenson CB, Thompson RC. CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Lett 2009;274:305-12.
    • (2009) Cancer Lett , vol.274 , pp. 305-312
    • Ehtesham, M.1    Mapara, K.Y.2    Stevenson, C.B.3    Thompson, R.C.4
  • 35
    • 32944459561 scopus 로고    scopus 로고
    • Activation of the nuclear factor kappaB pathway by astrocyte gene-1: Implications for tumor progression and metastasis
    • Emdad L, Sarkar D, Su ZZ, Randolph A, Boukerche H, Valerie K, et al. Activation of the nuclear factor kappaB pathway by astrocyte gene-1: Implications for tumor progression and metastasis. Cancer Res 2006;66:1509-16.
    • (2006) Cancer Res , vol.66 , pp. 1509-1516
    • Emdad, L.1    Sarkar, D.2    Su, Z.Z.3    Randolph, A.4    Boukerche, H.5    Valerie, K.6
  • 37
    • 0032545761 scopus 로고    scopus 로고
    • Priming in the brain, an immunologically privileged organ, elicits anti-tumor immunity
    • Fathallah-Shaykh HM, Gao W, Cho M, Herrera MA. Priming in the brain, an immunologically privileged organ, elicits anti-tumor immunity. In J Cancer 1998;75:266-76.
    • (1998) J Cancer , vol.75 , pp. 266-276
    • Fathallah-Shaykh, H.M.1    Gao, W.2    Cho, M.3    Herrera, M.A.4
  • 38
    • 56149092503 scopus 로고    scopus 로고
    • Cell death after spinal cord injury is exacerbated by rapid TNF-Alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane
    • Ferguson AR, Christensen RN, Gensel JC, Miller BA, Sun F, Beattie EC, et al. Cell death after spinal cord injury is exacerbated by rapid TNF-Alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane. J Neurosci 2008;28:11391-400.
    • (2008) J Neurosci , vol.28 , pp. 11391-11400
    • Ferguson, A.R.1    Christensen, R.N.2    Gensel, J.C.3    Miller, B.A.4    Sun, F.5    Beattie, E.C.6
  • 39
    • 34547197024 scopus 로고    scopus 로고
    • Spheres isolated from 9 L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells
    • Ghods AJ, Irvin D, Liu G, Yuan X, Abdulkadir IR, Tunici B, et al. Spheres isolated from 9 L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells. Stem Cells 2007;25:1645-53.
    • (2007) Stem Cells , vol.25 , pp. 1645-1653
    • Ghods, A.J.1    Irvin, D.2    Liu, G.3    Yuan, X.4    Abdulkadir, I.R.5    Tunici, B.6
  • 40
    • 0037135560 scopus 로고    scopus 로고
    • Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells
    • Giannone G, Ronde P, Gaire M, Haiech J, Takeda K. Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells. J Biol Chem 2002;277:26364-71.
    • (2002) J Biol Chem , vol.277 , pp. 26364-26371
    • Giannone, G.1    Ronde, P.2    Gaire, M.3    Haiech, J.4    Takeda, K.5
  • 41
    • 0034772516 scopus 로고    scopus 로고
    • Sulfasalazine, a potent suppressor of lymphoma growth by inhibition if the x(c)-cystine transporter: A new action for an old drug
    • Gout PW, Buckley AR, Simms CR, Bruchovsky N. Sulfasalazine, a potent suppressor of lymphoma growth by inhibition if the x(c)-cystine transporter: A new action for an old drug. Leukemia 2001;15:1633-40.
    • (2001) Leukemia , vol.15 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 42
    • 0041880122 scopus 로고    scopus 로고
    • SOX2 functions to maintain neural progenitor identity
    • Graham V, Khudyakov J, Ellis P, Pevny L. SOX2 functions to maintain neural progenitor identity. Neuron 2003;39:749-65.
    • (2003) Neuron , vol.39 , pp. 749-765
    • Graham, V.1    Khudyakov, J.2    Ellis, P.3    Pevny, L.4
  • 43
    • 0028168159 scopus 로고
    • TNF-Alpha increases the frequency of spontaneous miniature synaptic currents in cultured rat hippocampal neurons
    • Grassi F, Miles AM, Monaco L, Puntuieri A, Santoni A, Eusebi F. TNF-Alpha increases the frequency of spontaneous miniature synaptic currents in cultured rat hippocampal neurons. Brain Res 1994;65:226-30.
    • (1994) Brain Res , vol.65 , pp. 226-230
    • Grassi, F.1    Miles, A.M.2    Monaco, L.3    Puntuieri, A.4    Santoni, A.5    Eusebi, F.6
  • 44
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liasions: STAT3 and NF-kappaB collaboration and crosstalk in cancer
    • Grivennikov SI, Karin M. Dangerous liasions: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev 2010;21:11-9.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 45
    • 77957592789 scopus 로고    scopus 로고
    • Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
    • Gupta SC, Kim JH, Prasad S, Aggarwal BB. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metastasis Rev 2010;29:405-34.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 405-434
    • Gupta, S.C.1    Kim, J.H.2    Prasad, S.3    Aggarwal, B.B.4
  • 46
    • 0032558822 scopus 로고    scopus 로고
    • Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
    • Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr Biol 1998;8:1195-8.
    • (1998) Curr Biol , vol.8 , pp. 1195-1198
    • Haas-Kogan, D.1    Shalev, N.2    Wong, M.3    Mills, G.4    Yount, G.5    Stokoe, D.6
  • 47
    • 78649478724 scopus 로고    scopus 로고
    • Peripheral glutamate signaling in head and neck areas
    • Haas HS, Linecker A, Pfragner R, Sadjak A. Peripheral glutamate signaling in head and neck areas. Head Neck 2010;32:1554-72.
    • (2010) Head Neck , vol.32 , pp. 1554-1572
    • Haas, H.S.1    Linecker, A.2    Pfragner, R.3    Sadjak, A.4
  • 48
    • 3242674366 scopus 로고    scopus 로고
    • Cycloogenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: Correlation with angiogenesis and prognostic significance
    • Hara A, Okayasu I. Cycloogenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: Correlation with angiogenesis and prognostic significance. Acta Neuropathol 2004;108:43-8.
    • (2004) Acta Neuropathol , vol.108 , pp. 43-48
    • Hara, A.1    Okayasu, I.2
  • 50
    • 0027979670 scopus 로고
    • Generation of cytotoxic immune responses during the progression of a rat glioma
    • Holladay FP, Choudhuri R, Heitz T, Wood GW. Generation of cytotoxic immune responses during the progression of a rat glioma. J Neurosurg 1994;80:90-6.
    • (1994) J Neurosurg , vol.80 , pp. 90-96
    • Holladay, F.P.1    Choudhuri, R.2    Heitz, T.3    Wood, G.W.4
  • 51
    • 33748532939 scopus 로고    scopus 로고
    • The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
    • Hussain SF, Yang D, Suki D, Aldape K, Grimm E, Heimberger AB. The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro Oncol 2006;8:261-79.
    • (2006) Neuro Oncol , vol.8 , pp. 261-279
    • Hussain, S.F.1    Yang, D.2    Suki, D.3    Aldape, K.4    Grimm, E.5    Heimberger, A.B.6
  • 52
    • 70449367087 scopus 로고    scopus 로고
    • Curcumin analogue GO-YO30 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas
    • Hutzen B, Friedman L, Sobo M, Likn L, Cen L, De Angelis S, et al. Curcumin analogue GO-YO30 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas. In J Oncol 2009;35:867-72.
    • (2009) J Oncol , vol.35 , pp. 867-872
    • Hutzen, B.1    Friedman, L.2    Sobo, M.3    Likn, L.4    Cen, L.5    De Angelis, S.6
  • 53
    • 34547438107 scopus 로고    scopus 로고
    • Ca 2+-permeable AMPA receptors regulate growth of human glioblastoma via Akt activation
    • Ischiuchi S, Yoshida Y, Sugawara K, Aihara M, Ohtani T, Watanabe T, et al. Ca 2+-permeable AMPA receptors regulate growth of human glioblastoma via Akt activation. J Neurosci 2007;27:7987-8001.
    • (2007) J Neurosci , vol.27 , pp. 7987-8001
    • Ischiuchi, S.1    Yoshida, Y.2    Sugawara, K.3    Aihara, M.4    Ohtani, T.5    Watanabe, T.6
  • 54
    • 0036732391 scopus 로고    scopus 로고
    • Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells
    • Ischiuchi S, Tsuzuki K, Yoshida N, Hagimura N, Okado H, Miwa A, et al. Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells. Nat Med 2002;8:971-8.
    • (2002) Nat Med , vol.8 , pp. 971-978
    • Ischiuchi, S.1    Tsuzuki, K.2    Yoshida, N.3    Hagimura, N.4    Okado, H.5    Miwa, A.6
  • 55
    • 78449292592 scopus 로고    scopus 로고
    • Calpain 2 is required for glioblastoma cell invasion: Regulation of matrix metalloproteinase 2
    • Jang HS, Lai S, Greenwood JA. Calpain 2 is required for glioblastoma cell invasion: Regulation of matrix metalloproteinase 2. Neurochem Res 2010;35:1796-804.
    • (2010) Neurochem Res , vol.35 , pp. 1796-1804
    • Jang, H.S.1    Lai, S.2    Greenwood, J.A.3
  • 56
    • 0028889739 scopus 로고
    • Stimulation of inotropic glutamate receptors activates transcription factor NF-κB in primary neurons
    • Kaltschmidt C, Kaltschmidt B, Bacuerle PA. Stimulation of inotropic glutamate receptors activates transcription factor NF-κB in primary neurons. Proc Nat Acad Sci USA 1995;92:9618-22.
    • (1995) Proc Nat Acad Sci USA , vol.92 , pp. 9618-9622
    • Kaltschmidt, C.1    Kaltschmidt, B.2    Bacuerle, P.A.3
  • 57
    • 20444389341 scopus 로고    scopus 로고
    • Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1
    • Kang DC, Su ZZ, Sarkar D, Emdad L, Volsky DJ, Fisher PB. Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene 2005;353:8-15.
    • (2005) Gene , vol.353 , pp. 8-15
    • Kang, D.C.1    Su, Z.Z.2    Sarkar, D.3    Emdad, L.4    Volsky, D.J.5    Fisher, P.B.6
  • 58
  • 59
    • 35348879054 scopus 로고    scopus 로고
    • Silymarin and epithelial cancer chemoprevention: How close are we to bedside?
    • Kaur M, Agarwal R. Silymarin and epithelial cancer chemoprevention: How close are we to bedside? Toxicol Appl Pharmacol 2007;224:350-9.
    • (2007) Toxicol Appl Pharmacol , vol.224 , pp. 350-359
    • Kaur, M.1    Agarwal, R.2
  • 60
    • 33748750051 scopus 로고    scopus 로고
    • Cancer immunosuppression and autoimmune disease: Beyond immunosuppressive networks for tumor immunity
    • Kim R, Emi M, Tanabe K. Cancer immunosuppression and autoimmune disease: Beyond immunosuppressive networks for tumor immunity. Immunology 2006;119:254-64.
    • (2006) Immunology , vol.119 , pp. 254-264
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 61
    • 0032601166 scopus 로고    scopus 로고
    • Primary and secondary glioblastomas: From concept to clinical diagnosis
    • Kleihues P, Ohgaki H. Primary and secondary glioblastomas: From concept to clinical diagnosis. Neuro-Oncolol 1999;1:44-51.
    • (1999) Neuro-Oncolol , vol.1 , pp. 44-51
    • Kleihues, P.1    Ohgaki, H.2
  • 62
    • 0033964354 scopus 로고    scopus 로고
    • Phenotype vs genotype in the evolution of astrocytic brain tumors
    • Kleihues P, Ohgaki H. Phenotype vs genotype in the evolution of astrocytic brain tumors. Toxicol Pathol 2000;28:164-70.
    • (2000) Toxicol Pathol , vol.28 , pp. 164-170
    • Kleihues, P.1    Ohgaki, H.2
  • 63
    • 0030201466 scopus 로고    scopus 로고
    • Intracellular Ca2+ fluctuations modulate the rate of neuronal migration
    • Kumuro H, Rakic P. Intracellular Ca2+ fluctuations modulate the rate of neuronal migration. Neuron 1996;17:275-85.
    • (1996) Neuron , vol.17 , pp. 275-285
    • Kumuro, H.1    Rakic, P.2
  • 64
    • 51349137454 scopus 로고    scopus 로고
    • Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
    • Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 2008;269:199-225.
    • (2008) Cancer Lett , vol.269 , pp. 199-225
    • Kunnumakkara, A.B.1    Anand, P.2    Aggarwal, B.B.3
  • 65
    • 44849089702 scopus 로고    scopus 로고
    • Pten haploinsufficency accelerates formation of high-grade astrocytomas
    • Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, et al. Pten haploinsufficency accelerates formation of high-grade astrocytomas. Cancer Res 2008;68:3286-94.
    • (2008) Cancer Res , vol.68 , pp. 3286-3294
    • Kwon, C.H.1    Zhao, D.2    Chen, J.3    Alcantara, S.4    Li, Y.5    Burns, D.K.6
  • 66
    • 22644446255 scopus 로고    scopus 로고
    • Tuning of macrophage responses by Stat3-inducing cytokines: Molecular mechanisms and consequences in infection
    • Lang R. Tuning of macrophage responses by Stat3-inducing cytokines: Molecular mechanisms and consequences in infection. Immunobiology 2005;210:63-76.
    • (2005) Immunobiology , vol.210 , pp. 63-76
    • Lang, R.1
  • 67
    • 39849101377 scopus 로고    scopus 로고
    • Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity
    • Leonoudakis D, Zhao P, Beattie EC. Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity. J Neurosci 2008;28:2119-30.
    • (2008) J Neurosci , vol.28 , pp. 2119-2130
    • Leonoudakis, D.1    Zhao, P.2    Beattie, E.C.3
  • 68
    • 79960282808 scopus 로고    scopus 로고
    • Redox properties of the tissue factor Cys186-Cys209 disulfide bond
    • Liang HP, Brophy TM, Hogg PJ. Redox properties of the tissue factor Cys186-Cys209 disulfide bond. Biochem J 2011;437:455-60.
    • (2011) Biochem J , vol.437 , pp. 455-460
    • Liang, H.P.1    Brophy, T.M.2    Hogg, P.J.3
  • 69
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, Podsypania K, Bose S, Wamg SI, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypania, K.4    Bose, S.5    Wamg, S.I.6
  • 70
    • 33947270928 scopus 로고    scopus 로고
    • Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects through the PI3K/mTOR/ETS2 pathway
    • Li M, Zhang Z, Hill DL, Wang H, Zhang R. Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects through the PI3K/mTOR/ETS2 pathway. Cancer Res 2007;67:1988-96.
    • (2007) Cancer Res , vol.67 , pp. 1988-1996
    • Li, M.1    Zhang, Z.2    Hill, D.L.3    Wang, H.4    Zhang, R.5
  • 71
    • 84934443974 scopus 로고    scopus 로고
    • Curcumin as a chemosensitizer
    • Limtrakul P. Curcumin as a chemosensitizer. Adv Exp Med Biol 2007;595:269-300.
    • (2007) Adv Exp Med Biol , vol.595 , pp. 269-300
    • Limtrakul, P.1
  • 72
    • 22244458242 scopus 로고    scopus 로고
    • AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling
    • Lin CY, Lynch G, Gall CM. AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling. J Neurochem 2005;94:531-46.
    • (2005) J Neurochem , vol.94 , pp. 531-546
    • Lin, C.Y.1    Lynch, G.2    Gall, C.M.3
  • 73
    • 84934436717 scopus 로고    scopus 로고
    • Molecular targets of curcumin
    • Lin JK. Molecular targets of curcumin. Adv Exp Med Biol 2007;595:227-43.
    • (2007) Adv Exp Med Biol , vol.595 , pp. 227-243
    • Lin, J.K.1
  • 74
    • 79959794242 scopus 로고    scopus 로고
    • PI3Kinase signaling in glioblastoma
    • Lino MM, Merio A. PI3Kinase signaling in glioblastoma. J Neurooncol 2011;103:417-27.
    • (2011) J Neurooncol , vol.103 , pp. 417-427
    • Lino, M.M.1    Merio, A.2
  • 75
    • 33745006396 scopus 로고    scopus 로고
    • Ischemic insults direct glutamate receptor subunit 2-lacking AMPA receptors to synaptic sites
    • Liu B, Liao M, Mielke JG, Ning K, Chen Y, Li L, et al. Ischemic insults direct glutamate receptor subunit 2-lacking AMPA receptors to synaptic sites. J Neurosci 2006;26:5309-19.
    • (2006) J Neurosci , vol.26 , pp. 5309-5319
    • Liu, B.1    Liao, M.2    Mielke, J.G.3    Ning, K.4    Chen, Y.5    Li, L.6
  • 77
    • 20444442744 scopus 로고    scopus 로고
    • Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulates kinase
    • Lubin FD, Jhonston LD, Sweatt JD, Anderson AE. Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulates kinase. Neuroscience 2005;133:969-81.
    • (2005) Neuroscience , vol.133 , pp. 969-981
    • Lubin, F.D.1    Jhonston, L.D.2    Sweatt, J.D.3    Anderson, A.E.4
  • 81
    • 22144461394 scopus 로고    scopus 로고
    • Enteral formula selection: A product Review of Selected Product Catagories
    • Malone A. Enteral formula selection: A product Review of Selected Product Catagories. Pract Gastroenterol 2006;44-74.
    • (2006) Pract Gastroenterol , pp. 44-74
    • Malone, A.1
  • 82
    • 1842581857 scopus 로고    scopus 로고
    • Cutting edge: Human CD4+CD25+Tcells restrain the maturation and antigen-presenting function of dendritric cells
    • Misra N, Bayry J, Lacroix-Desmazes S, Kazatchkine MD, Kaveri SV. Cutting edge: Human CD4+CD25+Tcells restrain the maturation and antigen-presenting function of dendritric cells. J Immunol 2004;172:4676-80.
    • (2004) J Immunol , vol.172 , pp. 4676-4680
    • Misra, N.1    Bayry, J.2    Lacroix-Desmazes, S.3    Kazatchkine, M.D.4    Kaveri, S.V.5
  • 83
    • 27144483873 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 and faculititive glucose transporters GLUT1 and GLUT3: Putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes
    • Mobasheri A, Richardson S, Mobasheri R, Sakibael M, Hoyland JA. Hypoxia inducible factor-1 and faculititive glucose transporters GLUT1 and GLUT3: Putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes. Histol Histopathol 2005;20:1327-38.
    • (2005) Histol Histopathol , vol.20 , pp. 1327-1338
    • Mobasheri, A.1    Richardson, S.2    Mobasheri, R.3    Sakibael, M.4    Hoyland, J.A.5
  • 85
    • 73549104022 scopus 로고    scopus 로고
    • Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicity
    • Noch E, Khalili K. Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicity. Cancer Biol Ther 2009;8:1791-7.
    • (2009) Cancer Biol Ther , vol.8 , pp. 1791-1797
    • Noch, E.1    Khalili, K.2
  • 87
    • 84866147745 scopus 로고    scopus 로고
    • Current ternds in targeted therapies for glioblastoma multiforme
    • Ohka F, Natsume A, Wakabayashi T. Current ternds in targeted therapies for glioblastoma multiforme. Neurol Res Int 2012;2012:878425.
    • (2012) Neurol Res Int , vol.2012 , pp. 878425
    • Ohka, F.1    Natsume, A.2    Wakabayashi, T.3
  • 88
    • 0014937190 scopus 로고
    • Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine
    • Olney JW, Ho OL. Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine. Nature 1970;227:609-11.
    • (1970) Nature , vol.227 , pp. 609-611
    • Olney, J.W.1    Ho, O.L.2
  • 89
    • 0019202311 scopus 로고
    • Brain damage in mice from voluntary ingestion of glutamate and aspartate
    • Olney JW, Labruyere J, de Gubareff T. Brain damage in mice from voluntary ingestion of glutamate and aspartate. Neurobiol Toxicol 1980;2:125-9.
    • (1980) Neurobiol Toxicol , vol.2 , pp. 125-129
    • Olney, J.W.1    Labruyere, J.2    De Gubareff, T.3
  • 90
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: A crucial transcription factor for glial and neuronal cell function
    • O'Neill LA, Kaltschmidt C. NF-κB: A crucial transcription factor for glial and neuronal cell function. Trends Neurosci 1997;20:252-58.
    • (1997) Trends Neurosci , vol.20 , pp. 252-258
    • O'Neill, L.A.1    Kaltschmidt, C.2
  • 91
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999;18:6853-66.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 92
    • 0347480436 scopus 로고    scopus 로고
    • Differentiation of substrate and non-substrate inhibitors of transport system xc(-): And obligate exchanger of L-glutamate and L-cystine
    • Patel SA, Warren BA, Rhoderick JF, Bridges RJ. Differentiation of substrate and non-substrate inhibitors of transport system xc(-): And obligate exchanger of L-glutamate and L-cystine. Neuropharmacology 2004;46:273-84.
    • (2004) Neuropharmacology , vol.46 , pp. 273-284
    • Patel, S.A.1    Warren, B.A.2    Rhoderick, J.F.3    Bridges, R.J.4
  • 93
    • 67649619278 scopus 로고    scopus 로고
    • AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matric
    • Piao Y, Lu L, de Groot J. AMPA receptors promote perivascular glioma invasion via beta1 integrin-dependent adhesion to the extracellular matric. Neuro Oncol 2009;11:260-73.
    • (2009) Neuro Oncol , vol.11 , pp. 260-273
    • Piao, Y.1    Lu, L.2    De Groot, J.3
  • 95
    • 33745188839 scopus 로고    scopus 로고
    • Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
    • Plant K, Pelkey KA, Bortolotto ZA, Morita D, Terashima A, McBain CJ, et al. Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation. Nat Neurosci 2006;9:602-4.
    • (2006) Nat Neurosci , vol.9 , pp. 602-604
    • Plant, K.1    Pelkey, K.A.2    Bortolotto, Z.A.3    Morita, D.4    Terashima, A.5    McBain, C.J.6
  • 96
    • 84855708762 scopus 로고    scopus 로고
    • HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
    • Qiang L, Wu T, Zhang HW, Lu N, Hu R, Wang YJ, et al. HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway. Cell Death Differ 2012;19:284-94.
    • (2012) Cell Death Differ , vol.19 , pp. 284-294
    • Qiang, L.1    Wu, T.2    Zhang, H.W.3    Lu, N.4    Hu, R.5    Wang, Y.J.6
  • 97
    • 67650581533 scopus 로고    scopus 로고
    • Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma
    • Ravenna L, Sale P, Di Vito M, Russo A, Salvatori L, Tafani M, et al. Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma. Prostate 2009;69:1245-55.
    • (2009) Prostate , vol.69 , pp. 1245-1255
    • Ravenna, L.1    Sale, P.2    Di Vito, M.3    Russo, A.4    Salvatori, L.5    Tafani, M.6
  • 98
    • 79952184099 scopus 로고    scopus 로고
    • Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma
    • Reynes G, Vila V, Martin M, Parada A, Fleitas T, Reganon E, et al. Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma. J Neurooncol 2011;102:35-41.
    • (2011) J Neurooncol , vol.102 , pp. 35-41
    • Reynes, G.1    Vila, V.2    Martin, M.3    Parada, A.4    Fleitas, T.5    Reganon, E.6
  • 100
    • 0344642991 scopus 로고    scopus 로고
    • Baseline levels of glucose metabolites, glutamate and glycerol in malignant gliom assessed by sterotatic microdialysis
    • Roslin M, Henricksson R, Bergstrom P, Ungerstedt U, Bergenheim AT. Baseline levels of glucose metabolites, glutamate and glycerol in malignant gliom assessed by sterotatic microdialysis. J Neuro-oncol 2003;61:151-60.
    • (2003) J Neuro-oncol , vol.61 , pp. 151-160
    • Roslin, M.1    Henricksson, R.2    Bergstrom, P.3    Ungerstedt, U.4    Bergenheim, A.T.5
  • 102
    • 0027177239 scopus 로고
    • Responses of human glioblastoma cells to human natural tumor necrosis factor-Alpha: Susceptibility, mechanics of resistance and cytokine production studies
    • Sakuma S, Sawamura Y, Tada M, Aida T, Abe H, Suzuki K, et al. Responses of human glioblastoma cells to human natural tumor necrosis factor-Alpha: Susceptibility, mechanics of resistance and cytokine production studies. J Neurooncol 1993;15:197-208.
    • (1993) J Neurooncol , vol.15 , pp. 197-208
    • Sakuma, S.1    Sawamura, Y.2    Tada, M.3    Aida, T.4    Abe, H.5    Suzuki, K.6
  • 103
    • 9144273408 scopus 로고    scopus 로고
    • Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells
    • Schwanborn J, Lindecke A. Elvers M, Horojschi V, Kerick M, Rafigh M, et al. Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Geonomics 2003;4:46.
    • (2003) BMC Geonomics , vol.4 , pp. 46
    • Schwanborn, J.1    Lindecke, A.2    Elvers, M.3    Horojschi, V.4    Kerick, M.5    Rafigh, M.6
  • 104
    • 78549283855 scopus 로고    scopus 로고
    • Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
    • Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, et al. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res 2010;70:8981-7.
    • (2010) Cancer Res , vol.70 , pp. 8981-8987
    • Seltzer, M.J.1    Bennett, B.D.2    Joshi, A.D.3    Gao, P.4    Thomas, A.G.5    Ferraris, D.V.6
  • 105
    • 82255162738 scopus 로고    scopus 로고
    • Targeting inflammation-induced transcription factor activation: An open frontier for glioma therapy
    • Sen E. Targeting inflammation-induced transcription factor activation: An open frontier for glioma therapy. Drug Discov Today 2011;16:1044-51.
    • (2011) Drug Discov Today , vol.16 , pp. 1044-1051
    • Sen, E.1
  • 106
    • 0029952677 scopus 로고    scopus 로고
    • Possible involvement of calpain in the growth of estrogen receptor positive breast cancer cells
    • Shiba E, Kim S, Fujitani M, Kambayashi I, Tsujimoto S, Shimomura K, et al. Possible involvement of calpain in the growth of estrogen receptor positive breast cancer cells. Anticancer Res 1996;16:773-7.
    • (1996) Anticancer Res , vol.16 , pp. 773-777
    • Shiba, E.1    Kim, S.2    Fujitani, M.3    Kambayashi, I.4    Tsujimoto, S.5    Shimomura, K.6
  • 107
    • 70350712285 scopus 로고    scopus 로고
    • Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worst outcome
    • Shnaper S, Desbaillets I, Brown DA, Murat A, Migliavacca E, Schluep M, et al. Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worst outcome. In J Cancer 2009;125:2624-30.
    • (2009) J Cancer , vol.125 , pp. 2624-2630
    • Shnaper, S.1    Desbaillets, I.2    Brown, D.A.3    Murat, A.4    Migliavacca, E.5    Schluep, M.6
  • 109
    • 67349168435 scopus 로고    scopus 로고
    • Role of macrophages in tumor progression
    • Siveen KS, Kuttan G. Role of macrophages in tumor progression. Immunol Lett 2009;123:97-102.
    • (2009) Immunol Lett , vol.123 , pp. 97-102
    • Siveen, K.S.1    Kuttan, G.2
  • 111
    • 0023583117 scopus 로고
    • Plasma amino acid concentrations in normal adults ingesting aspartame and monosodium L-glutamate as part of a soup/beverage meal
    • Stegink LD, Filer LJ Jr, Baker GL. Plasma amino acid concentrations in normal adults ingesting aspartame and monosodium L-glutamate as part of a soup/beverage meal. Metabolism 1987;36:1073-9.
    • (1987) Metabolism , vol.36 , pp. 1073-1079
    • Stegink, L.D.1    Filer Jr., L.J.2    Baker, G.L.3
  • 112
    • 16244376446 scopus 로고    scopus 로고
    • Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-Alpha
    • Stellwagen D, Beattie EC, Seo JY, Malenka RC. Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-Alpha. J Neurosci 2005;25:3219-28.
    • (2005) J Neurosci , vol.25 , pp. 3219-3228
    • Stellwagen, D.1    Beattie, E.C.2    Seo, J.Y.3    Malenka, R.C.4
  • 113
    • 27344452342 scopus 로고    scopus 로고
    • NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth
    • Stepulak A, Sifringer M, Rzeski W, Endesfelder S, Gratopp A, Pohl EE, et al. NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth. Proc Natl Acad Sci USA 2005;102:15605-10.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15605-15610
    • Stepulak, A.1    Sifringer, M.2    Rzeski, W.3    Endesfelder, S.4    Gratopp, A.5    Pohl, E.E.6
  • 115
    • 77957274653 scopus 로고    scopus 로고
    • Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment
    • Tafani M, Russo A, Di Vito M, Sale P, Pellegrini L, Schito L, et al. Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment. Cancer Sci 2010;101:1014-23.
    • (2010) Cancer Sci , vol.101 , pp. 1014-1023
    • Tafani, M.1    Russo, A.2    Di Vito, M.3    Sale, P.4    Pellegrini, L.5    Schito, L.6
  • 116
    • 79953865922 scopus 로고    scopus 로고
    • Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma
    • Tafani M, Di Vito M, Frati A, Pelligrini L, De Dantis E, Sette G, et al. Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma. J Neuroinflammation 2011;8:32.
    • (2011) J Neuroinflammation , vol.8 , pp. 32
    • Tafani, M.1    Di Vito, M.2    Frati, A.3    Pelligrini, L.4    De Dantis, E.5    Sette, G.6
  • 118
    • 77956322561 scopus 로고    scopus 로고
    • Neurotoxicity by microglia: Mechanisms and potential therapeutic strategy
    • Takeuchi H Neurotoxicity by microglia: Mechanisms and potential therapeutic strategy. Clin Exp Neuroimmunol 2010;1:12-21.
    • (2010) Clin Exp Neuroimmunol , vol.1 , pp. 12-21
    • Takeuchi, H.1
  • 119
  • 120
    • 0033634827 scopus 로고    scopus 로고
    • Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and stauroporine
    • Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP, et al. Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and stauroporine. Mol Cell 2000;6:909-19.
    • (2000) Mol Cell , vol.6 , pp. 909-919
    • Walker, E.H.1    Pacold, M.E.2    Perisic, O.3    Stephens, L.4    Hawkins, P.T.5    Wymann, M.P.6
  • 122
    • 73949147048 scopus 로고    scopus 로고
    • Regulation of cancer invasion by reactive oxygen species and Tks family scaffold proteins
    • Weaver AM. Regulation of cancer invasion by reactive oxygen species and Tks family scaffold proteins. Sci Signal 2009;2:56.
    • (2009) Sci Signal , vol.2 , pp. 56
    • Weaver, A.M.1
  • 124
    • 33749375248 scopus 로고    scopus 로고
    • Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/KF-kB signaling
    • Widera D, Mikenberg I, Elvers M, Kaltschmidt C, Kaltschmidt B. Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/KF-kB signaling. BMC Neurosci 2006;7:64.
    • (2006) BMC Neurosci , vol.7 , pp. 64
    • Widera, D.1    Mikenberg, I.2    Elvers, M.3    Kaltschmidt, C.4    Kaltschmidt, B.5
  • 125
    • 78049270536 scopus 로고    scopus 로고
    • Glioma cancer stem cells induce immunosuppressive macrophages/microglia
    • Wu A, Wei J, Kong LK, Wang Y, Priebe W, Oiao W, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 2010;12:1113-25.
    • (2010) Neuro Oncol , vol.12 , pp. 1113-1125
    • Wu, A.1    Wei, J.2    Kong, L.K.3    Wang, Y.4    Priebe, W.5    Oiao, W.6
  • 126
    • 0033198997 scopus 로고    scopus 로고
    • Glioma cells release excitotoxic concentrations of glutamate
    • Ye ZC, Sontheimer H. Glioma cells release excitotoxic concentrations of glutamate. Cancer Res 1999;59:4383-91.
    • (1999) Cancer Res , vol.59 , pp. 4383-4391
    • Ye, Z.C.1    Sontheimer, H.2
  • 127
    • 0033573392 scopus 로고    scopus 로고
    • Compromised glutamate transport in human glioma cells: Reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange
    • Ye ZC, Rothstein JD, Sontheimer H. Compromised glutamate transport in human glioma cells: Reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange. J Neurosci 1999;19:10767-77.
    • (1999) J Neurosci , vol.19 , pp. 10767-10777
    • Ye, Z.C.1    Rothstein, J.D.2    Sontheimer, H.3
  • 129
    • 33644928754 scopus 로고    scopus 로고
    • Green tea and its polyphenol catechins: Medicinal uses in cancer and noncancer applications
    • Zaveri NT. Green tea and its polyphenol catechins: Medicinal uses in cancer and noncancer applications. Life Sci 2006;78:2073-80.
    • (2006) Life Sci , vol.78 , pp. 2073-2080
    • Zaveri, N.T.1
  • 130
    • 0034652697 scopus 로고    scopus 로고
    • Fractalkine modulate TNF-Alpha secretion and neurotoxicity induced by microglial activation
    • Zujovic V, Benavides J, Vige X, Carter C, Taupin V. Fractalkine modulate TNF-Alpha secretion and neurotoxicity induced by microglial activation. Glia 2000;29:305-15.
    • (2000) Glia , vol.29 , pp. 305-315
    • Zujovic, V.1    Benavides, J.2    Vige, X.3    Carter, C.4    Taupin, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.