Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

Cancer Cell

Volumn 18, Issue 3, 2010, Pages 207-219

  Wang, Jian Bin ^a   Erickson, Jon W ^a   Fuji, Reina ^a,c   Ramachandran, Sekar ^a   Gao, Ping ^b   Dinavahi, Ramani ^b   Wilson, Kristin F ^a   Ambrosio, Andre L B ^a,d   Dias, Sandra M G ^a,d   Dang, Chi V ^b   Cerione, Richard A ^a  

^a Department of Obstetrics Gynecology   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GENENTECH INC   (United States)

^d LABORATÓRIO NACIONAL DE LUZ SÍNCROTRON   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; ENZYME INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CARCINOGENESIS; CATALYSIS; CELL METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CELL TRANSFORMATION; DRUG EFFECTS; ENZYMOLOGY; FEMALE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; ENZYME INHIBITORS; FEMALE; FIBROBLASTS; GLUTAMINASE; HUMANS; MICE; MITOCHONDRIA; NIH 3T3 CELLS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 77956497712     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2010.08.009     Document Type: Article

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