Fractalkine modulates TNF-α secretion and neurotoxicity induced by microglial activation

GLIA

Volumn 29, Issue 4, 2000, Pages 305-315

  Zujovic, Violetta ^a   Benavides, Jesús ^a   Vigé, Xavier ^a   Carter, Christopher ^a   Taupin, Véronique ^a,b  

^a SANOFI   (France)

^b NONE   (France)

Author keywords

Chemokine; Fractalkine receptor; Hippocampus; LPS; Microglia; Neuronal death; Rat

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE (C X3 C MOTIF) LIGAND 1; CHEMOKINE (C-X3-C MOTIF) LIGAND 1; CX3C CHEMOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; NERVE PROTEIN; TUMOR NECROSIS FACTOR ALPHA; V28 RECEPTOR; VIRUS RECEPTOR;

ANIMAL; ARTICLE; ASTROCYTE; BIOSYNTHESIS; CELL CULTURE; CELL SURVIVAL; COCULTURE; CYTOLOGY; DEGENERATIVE DISEASE; DRUG EFFECT; ENCEPHALITIS; HIPPOCAMPUS; METABOLISM; MICROGLIA; NERVE CELL; PHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION;

ANIMALS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES, CX3C; CHEMOKINES, CXC; COCULTURE TECHNIQUES; ENCEPHALITIS; HIPPOCAMPUS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICROGLIA; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; RATS; RECEPTORS, CYTOKINE; RECEPTORS, HIV; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034652697     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(20000215)29:4<305::AID-GLIA2>3.0.CO;2-V     Document Type: Article

References (45)

1. 3C motif. Nature 385:640-644.
2. Benveniste EN. 1997. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J Mol Med 75:165-173.
3. Bronstein DM, Perez-Otano I, Sun V, Mullis Sawin SB, Chan J , Wu G-C, Hudson L-Y, Kong J-S, McMillian MK. 1995. Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures. Brain Res 704:112-116.
4. 3C chemokine fractalkine. Biochem Biophys Res Commun 253:728-732.
5. 3C chemokine fractalkine and a fusion coreceptor for HIV-1. J Biol Chem 273:23799-23804.
6. Devalaraja MN, Richmond A. 1999. Multiple chemotactic factors: fine control and redundancy? Trends Pharmacol Sci 20:151-156.
7. Emerit MB, Segovia J, Alho H, Mastrangelo MJ, Wise BC. 1989. Hippocampal membranes contain a neurotrophic activity that stimulates cholinergic properties of fetal rat septal neurons cultured under serum-free conditions. J Neurochem 52:952-961.
8. Gourmala NG, Limonta S, Bochelen D, Sauter A, Boddeke HW. 1999. Localisation of macrophage inflammatory protein: macrophage inflammatory protein 1 expression in rat brain after peripheral administration of lipopolysaccharide and focal cerebral ischemia. Neuroscience 88:1255-1266.
9. Hall GL, Compston A, Scolding NJ. 1997. β-interferon and multiple sclerosis. Trends Neurosci 20:63-67.
10. 3CR1-expressing microglia. Proc Natl Acad Sci USA 95:10896-10901.
11. Hausmann EHS, Berman NEJ, Wang Y-Y, Meara JB, Wood GW, Klein RM. 1998. Selective mRNA expression following brain injury. Brain Res 788:49-59.
12. Horuk R. 1999. Chemokine receptors and HIV-1: the fusion of two major research fields. Immunol Today 20:89-94.
13. 3CR1, which mediates both leukocyte migration and adhesion. Cell 91:521-530.
14. Jiang Y, Salafranca MN, Adhikari S, Xia Y, Feng L, Sonntag MK, deFiebre CM, Pennell NA, Streit W J, Harrison JK. 1998. Chemokine receptor expression in cultured rat glia and rat experimental allergic encephalomyelitis. J Neuroimmunol 186:1-12.
15. Kanazawa N, Nakamura T, Tashiro K, Muramatsu M, Morita K, Yoneda K, Inaba K, Imamura S, Honjo T. 1999. Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells. Eur J Immunol 29:1925-1932.
16. Karpus WJ, Luckas NW, McRae BL, Strieter RM, Kunkel SL, Miller SD. 1995. An important role for the chemokine macrophage inflammatory protein-1α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol 155:5003-5010.
17. Kennedy KJ, Strieter RM, Kundel SL, Lukacs NW, Karpus WJ. 1998. Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1 α and monocyte chemotactic protein-1. J Neuroimmunol 92:98-108.
18. Khandaker MH, Xu L, Rahimpour R, Mitchell G, DeVries ME, Pickering JG, Singhal SK, Feldman RD, Kelvin DJ. 1998. CXCR1 and CXCR2 are rapidly down modulated by bacterial endotoxin through a unique agonist-independent, tyrosine kinase-dependent mechanism. J Immunol 161:1930-1938.
19. Kossman T, Stahel PF, Lenzlinger PM, Redl H, Dubs RW, Trentz O, Schlag G, Morganti-Kossman MC. 1997. Interleukin-8 released into the cerebrospinal fluid after brain injury is associated with blood-brain-barrier dysfunction and nerve growth factor production. J Cereb Blood Flow Metab 17:280-289.
20. Littman DR. 1998. Chemokine receptors: keys to AIDS pathogenesis? Cell 93:667-680.
21. Meda L, Cassatella MA, Szendrei GI, Otvos L Jr, Baron P, Villalba M, Ferrari D, Rossi F. 1995. Activation of microglial cells by β-amyloid protein and Interferon-γ. Nature 374:647-650.
22. Mennicken F, Maki R, DeSouza EB, Quirion R. 1999. Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning. Trends Pharmacol Sci 20:73-78.
23. Merrill JE, Koyanagi Y, Zack J, Thomas L, Martin F, Chen IS. 1992. Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1. J Virol 66:2217-2225.
24. Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. 1993. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 151:2132-2141.
25. Meucci O, Fatatis A, Simen AA, Bushell TJ, Gray PW, Miller RJ. 1998. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc Natl Acad Sci USA 95:14500-14505.
26. Mullen RJ, Buck CR, Smith AM. 1992. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116:201-211.
27. Murphy GM, Jia X-C, Song Y, Ong E, Shrivastava R, Bocchini V, Lee Y L, Eng L F. 1995. Macrophage inflammatory protein 1-α mRNA expression in an immortalized microglial cell line and cortical astrocyte cultures. J Neurosci Res 40:755-763.
28. 3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? FEBS Lett 429:167-172.
29. Ohtani Y, Minami M, Kawagushi N, Nishiyori A, Yamamoto J, Takami S, Satoh M. 1998. Expression of SDF-1α and CXCR4 chemokine receptor mRNA in cultured rat glial and neuronal cells. Neuroscience 249:163-166.
30. Pan Y, Lloyd C, Zhou H, Dollch S, Deeds J, Gonzalo J-A, Vath J, Gosselin M, Ma J, Dussault B, Woolf E, Alperin G, Culpepper J, Gutierrez-Ramos JC, Gearing D. 1997. Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature 387:611-617.
31. Proudfoot AEI, Wells TNC, Clapham PR. 1999. Chemokine receptors - future therapeutic targets for HIV? Biochem Pharmacol 57:451-463.
32. Rossi DL, Hardiman G, Copeland, NG, Gibert DJ, Jenkins N, Zlotnik A, Bazan JF. 1998. Cloning and characterization of a new type of mouse chemokine. Genomics 47:163-170.
33. Ruff MR, Gifford GE. 1981. Tumor necrosis factor. In: Pick E, editor. Lymphokines. Vol 2. San Diego: Academic Press. p 235-272.
34. Sallusto F, Schaerli P, Loetscher P, Schaniel C, Lenig D, Mackay CR, Qin S, Lanzavecchia A. 1998. Rapid and coordinate switch in chemokine receptor expression during dendritic maturation. Eur J Immunol 28:2760-2769.
35. Schwaeble WJ, Stover CM, Schall TJ, Dairaghi DJ, Trinder PKE, Linington C, Iglesias A, Schubart A, Lynch NJ, Weihe E, Schäfer MKH. 1998. Neuronal expression of fractalkine in the presence and absence of inflammation. FEBS Lett 439:203-207.
36. Selmaj KW, Raine CS, Cannella B, Brosnan CF. 1991. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87:949-954.
37. Selmaj KW, Raine CS. 1988. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339-346.
38. Sharief MK, Hentges R. 1991. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis. N Engl J Med 325:467-472.
39. Shi B, Raina J, Lorenzo A, Busciglio J, Gabudza D. 1998. Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia. J Neurovirol 4:281-290.
40. Sorensen TL, Tani M, Jensen J, Pierce V, Luchinetti C, Folcik VA, Qin S, Rottman J, Sellebjerg F, Strieter RM, Frederiksen JL, Ransohoff RM. 1999. Expression of specific chemokines and chemokines receptors in the central nervous system of multiple sclerosis patients. J Clin Invest 103:807-815.
41. Spleiss O, Gourmala N, Boddeke HW, Sauter A, Fiebich BL, Berger M, Gebicke-Haerter PJ. 1998. Cloning rat HIV-1-chemokine co-receptor CKR5 from microglia and upregulation of its mRNA in ischémie endotoxemic rat brain. J Neurosci Res 53:16-28.
42. Spranger M, Fontana A. 1996. Activation of microglia: a dangerous interlude in immune function in the brain. Neuroscientist 2:293-299.
43. Wells TNC, Power CA, Proudfoot AEI. 1998. Definition, function and pathophysiological significance of chemokine receptors. Trends Pharmacol Sci 19:376-380.
44. Yeung MC, Pulliam L, Lau AS. 1995. The HIV envelope protein gp120 is toxic to human brain-cell cultures through the induction of interleukin-6 and tumor necrosis factor a. AIDS 9:137-143.
45. Zhou Y, Yand Y, Warr G, Bravo R. 1999. LPS down regulates the expression of chemokine receptor CCR2 in mice and abolishes macrophage infiltration in acute inflammation. J Leukoc Biol 65:265-269.