메뉴 건너뛰기




Volumn 132, Issue 1, 2013, Pages 1-16

Systems genetics in "-omics" era: Current and future development

Author keywords

Genetic network; Genome wide association studies; High throughput technology; Systems genetics

Indexed keywords


EID: 84873718401     PISSN: 14317613     EISSN: 16117530     Source Type: Journal    
DOI: 10.1007/s12064-012-0168-x     Document Type: Review
Times cited : (18)

References (210)
  • 1
    • 77958508815 scopus 로고    scopus 로고
    • SLOPE: A quick and accurate method for locating non-SNP structural variation from targeted next-generation sequence data
    • 10.1093/bioinformatics/btq528 20876606 1:CAS:528:DC%2BC3cXhtlensbrP
    • Abel HJ, Duncavage EJ, Becker N, Armstrong JR, Magrini VJ, Pfeifer JD (2010) SLOPE: a quick and accurate method for locating non-SNP structural variation from targeted next-generation sequence data. Bioinformatics 26(21):2684-2688. doi: 10.1093/bioinformatics/btq528
    • (2010) Bioinformatics , vol.26 , Issue.21 , pp. 2684-2688
    • Abel, H.J.1    Duncavage, E.J.2    Becker, N.3    Armstrong, J.R.4    Magrini, V.J.5    Pfeifer, J.D.6
  • 2
    • 79951961326 scopus 로고    scopus 로고
    • AGE: Defining breakpoints of genomic structural variants at single-nucleotide resolution, through optimal alignments with gap excision
    • 10.1093/bioinformatics/btq713 21233167 1:CAS:528:DC%2BC3MXis1ersL4%3D
    • Abyzov A, Gerstein M (2011) AGE: defining breakpoints of genomic structural variants at single-nucleotide resolution, through optimal alignments with gap excision. Bioinformatics 27(5):595-603. doi: 10.1093/bioinformatics/ btq713
    • (2011) Bioinformatics , vol.27 , Issue.5 , pp. 595-603
    • Abyzov, A.1    Gerstein, M.2
  • 3
    • 79951970227 scopus 로고    scopus 로고
    • CNVnator: An approach to discover, genotype and characterize typical and atypical CNVs from family and population genome sequencing
    • 10.1101/gr.114876.110 21324876 1:CAS:528:DC%2BC3MXnsFylsrc%3D
    • Abyzov A, Urban AE, Snyder M, Gerstein M (2011) CNVnator: an approach to discover, genotype and characterize typical and atypical CNVs from family and population genome sequencing. Genome Res 21:974-984. doi: 10.1101/gr.114876.110
    • (2011) Genome Res , vol.21 , pp. 974-984
    • Abyzov, A.1    Urban, A.E.2    Snyder, M.3    Gerstein, M.4
  • 4
    • 84859169904 scopus 로고    scopus 로고
    • Systematic detection of epistatic interactions based on allele pair frequencies
    • 10.1371/journal.pgen.1002463 22346757 1:CAS:528:DC%2BC38XivVWgs7k%3D
    • Ackermann M, Beyer A (2012) Systematic detection of epistatic interactions based on allele pair frequencies. PLoS Genet 8(2):e1002463. doi: 10.1371/journal.pgen.1002463
    • (2012) PLoS Genet , vol.8 , Issue.2 , pp. 1002463
    • Ackermann, M.1    Beyer, A.2
  • 5
    • 34548423292 scopus 로고    scopus 로고
    • The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: Implications for QTL discovery and systems genetics
    • 10.1007/s00335-007-9045-1
    • Adam R, Fernando PMV, Wang W, Leonard M, David WT (2007) The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mamm Genome 18:473-481. doi: 10.1007/s00335-007-9045-1
    • (2007) Mamm Genome , vol.18 , pp. 473-481
    • Adam, R.1    Fernando, P.M.V.2    Wang, W.3    Leonard, M.4    David, W.T.5
  • 6
    • 25444482801 scopus 로고    scopus 로고
    • Speeding disease gene discovery by sequence based candidate prioritization
    • 10.1186/1471-2105-6-55 15766383
    • Adie EA, Adams RR, Evans KL, Porteous DJ, Pickard BS (2005) Speeding disease gene discovery by sequence based candidate prioritization. BMC Bioinformatics 6:55. doi: 10.1186/1471-2105-6-55
    • (2005) BMC Bioinformatics , vol.6 , pp. 55
    • Adie, E.A.1    Adams, R.R.2    Evans, K.L.3    Porteous, D.J.4    Pickard, B.S.5
  • 7
    • 33645104470 scopus 로고    scopus 로고
    • SUSPECTS: Enabling fast and effective prioritization of positional candidates
    • 10.1093/bioinformatics/btk031 16423925 1:CAS:528:DC%2BD28Xit1Ontrk%3D
    • Adie EA, Adams RR, Evans KL, Porteous DJ, Pickard BS (2006) SUSPECTS: enabling fast and effective prioritization of positional candidates. Bioinformatics 22(6):773-774. doi: 10.1093/bioinformatics/btk031
    • (2006) Bioinformatics , vol.22 , Issue.6 , pp. 773-774
    • Adie, E.A.1    Adams, R.R.2    Evans, K.L.3    Porteous, D.J.4    Pickard, B.S.5
  • 9
    • 67650889108 scopus 로고    scopus 로고
    • Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids
    • 10.1371/journal.pcbi.1000407 19521529
    • Ahn S, Wang RT, Park CC, Lin A, Leahy RM, Lange K, Smith DJ (2009) Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids. PLoS Comput Biol 5(6):e1000407. doi: 10.1371/journal.pcbi.1000407
    • (2009) PLoS Comput Biol , vol.5 , Issue.6 , pp. 1000407
    • Ahn, S.1    Wang, R.T.2    Park, C.C.3    Lin, A.4    Leahy, R.M.5    Lange, K.6    Smith, D.J.7
  • 10
    • 80054757930 scopus 로고    scopus 로고
    • Construction of gene regulatory networks using biclustering and bayesian networks
    • 10.1186/1742-4682-8-39
    • Alakwaa FM, Solouma NH, Kadah YM (2011) Construction of gene regulatory networks using biclustering and bayesian networks. Theor Biol & Med Modelling 8:39. doi: 10.1186/1742-4682-8-39
    • (2011) Theor Biol & Med Modelling , vol.8 , pp. 39
    • Alakwaa, F.M.1    Solouma, N.H.2    Kadah, Y.M.3
  • 11
    • 80051628891 scopus 로고    scopus 로고
    • Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi
    • 10.1186/1471-2105-12-342 21849035 1:CAS:528:DC%2BC3MXhtFKms7vP
    • Axelsson E, Sandmann T, Horn T, Boutros M, Huber W, Fischer B (2011) Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi. BMC Bioinformatics 12:342. doi: 10.1186/1471-2105-12-342
    • (2011) BMC Bioinformatics , vol.12 , pp. 342
    • Axelsson, E.1    Sandmann, T.2    Horn, T.3    Boutros, M.4    Huber, W.5    Fischer, B.6
  • 13
    • 81755177857 scopus 로고    scopus 로고
    • Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways
    • 10.1371/journal.pgen.1002377 22125496 1:CAS:528:DC%2BC3MXhs1Smt7%2FO
    • Babu M, Díaz-Mejía JJ, Vlasblom J, Gagarinova A, Phanse S, Graham C, Yousif F, Ding H et al (2011) Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways. PLoS Genet 7(11):e1002377. doi: 10.1371/journal.pgen.1002377
    • (2011) PLoS Genet , vol.7 , Issue.11 , pp. 1002377
    • Babu, M.1    Díaz-Mejía, J.J.2    Vlasblom, J.3    Gagarinova, A.4    Phanse, S.5    Graham, C.6    Yousif, F.7    Ding, H.8
  • 14
    • 77955464738 scopus 로고    scopus 로고
    • Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3
    • doi: 10.1073/pnas.1007462107
    • Baldwin A, Grueneberg DA, Hellner K, Sawyer J, Grace M, Li W, Harlow E, Munger K (2010) Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3. Proc Natl Acad Sci USA 107(28):12463-12468. doi: 10.1073/pnas.1007462107
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.28 , pp. 12463-12468
    • Baldwin, A.1    Grueneberg, D.A.2    Hellner, K.3    Sawyer, J.4    Grace, M.5    Li, W.6    Harlow, E.7    Munger, K.8
  • 15
    • 77951240586 scopus 로고    scopus 로고
    • Network properties of complex human disease genes identified through genome-wide association studies
    • 10.1371/journal.pone.0008090 19956617
    • Barrenas F, Chavali S, Holme P, Mobini R, Benson M (2009) Network properties of complex human disease genes identified through genome-wide association studies. PLoS ONE 4(11):e8090. doi: 10.1371/journal.pone.0008090
    • (2009) PLoS ONE , vol.4 , Issue.11 , pp. 8090
    • Barrenas, F.1    Chavali, S.2    Holme, P.3    Mobini, R.4    Benson, M.5
  • 16
    • 77953245945 scopus 로고    scopus 로고
    • Automated identification of pathways from quantitative genetic interaction data
    • 10.1038/msb.2010.27 20531408
    • Battle A, Jonikas MC, Walter P, Weissman JS, Koller D (2010) Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol 6:379. doi: 10.1038/msb.2010.27
    • (2010) Mol Syst Biol , vol.6 , pp. 379
    • Battle, A.1    Jonikas, M.C.2    Walter, P.3    Weissman, J.S.4    Koller, D.5
  • 17
    • 84865077624 scopus 로고    scopus 로고
    • Network biology methods integrating biological data for translational science
    • 10.1093/bib/bbr075 22390873
    • Bebek G, Koyutürk M, Price ND, Chance MR (2012) Network biology methods integrating biological data for translational science. Brief Bioinform 13(4):446-459. doi: 10.1093/bib/bbr075
    • (2012) Brief Bioinform , vol.13 , Issue.4 , pp. 446-459
    • Bebek, G.1    Koyutürk, M.2    Price, N.D.3    Chance, M.R.4
  • 18
    • 34447569298 scopus 로고    scopus 로고
    • Copy number variants and genetic traits: Closer to the resolution of phenotypic to genotypic variability
    • 10.1038/nrg2149 17637735 1:CAS:528:DC%2BD2sXnvVekt7k%3D
    • Beckmann JS, Estivill X, Antonarakis SE (2007) Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability. Nat Rev Genet 8:639-646. doi: 10.1038/nrg2149
    • (2007) Nat Rev Genet , vol.8 , pp. 639-646
    • Beckmann, J.S.1    Estivill, X.2    Antonarakis, S.E.3
  • 19
    • 79952104806 scopus 로고    scopus 로고
    • A twin approach to unraveling epigenetics
    • 10.1016/j.tig.2010.12.005 21257220 1:CAS:528:DC%2BC3MXjsV2htr8%3D
    • Bell JT, Spector TD (2011) A twin approach to unraveling epigenetics. Trends Genet 27(3):116-125. doi: 10.1016/j.tig.2010.12.005
    • (2011) Trends Genet , vol.27 , Issue.3 , pp. 116-125
    • Bell, J.T.1    Spector, T.D.2
  • 20
    • 80051558597 scopus 로고    scopus 로고
    • Putting genetic interactions in context through a global modular decomposition
    • 10.1101/gr.117176.110 21715556 1:CAS:528:DC%2BC3MXpvFeqsLo%3D
    • Bellay J, Atluri G, Sing TL, Toufighi K, Costanzo M, Ribeiro PSM, Pandey G, Baller J et al (2011) Putting genetic interactions in context through a global modular decomposition. Genome Res 21:1375-1387. doi: 10.1101/gr.117176. 110
    • (2011) Genome Res , vol.21 , pp. 1375-1387
    • Bellay, J.1    Atluri, G.2    Sing, T.L.3    Toufighi, K.4    Costanzo, M.5    Ribeiro, P.S.M.6    Pandey, G.7    Baller, J.8
  • 21
    • 1542351273 scopus 로고    scopus 로고
    • Genomics tools for QTL analysis and gene discovery
    • 10.1016/j.pbi.2004.01.011 15003212 1:CAS:528:DC%2BD2cXhslCiu7k%3D
    • Borevitz JO, Chory J (2004) Genomics tools for QTL analysis and gene discovery. Curr Opin Plant Biol 7:132-136. doi: 10.1016/j.pbi.2004.01.011
    • (2004) Curr Opin Plant Biol , vol.7 , pp. 132-136
    • Borevitz, J.O.1    Chory, J.2
  • 22
    • 33846515112 scopus 로고    scopus 로고
    • Partial least squares: A versatile tool for the analysis of high-dimensional genomic data
    • 10.1093/bib/bbl016 16772269 1:CAS:528:DC%2BD2sXjsVKks78%3D
    • Boulesteix AL, Strimmer K (2007) Partial least squares: a versatile tool for the analysis of high-dimensional genomic data. Brief Bioinform 8(1):32-44. doi: 10.1093/bib/bbl016
    • (2007) Brief Bioinform , vol.8 , Issue.1 , pp. 32-44
    • Boulesteix, A.L.1    Strimmer, K.2
  • 23
    • 0037177625 scopus 로고    scopus 로고
    • Genetic dissection of transcriptional regulation in budding yeast
    • 10.1126/science.1069516 11923494 1:CAS:528:DC%2BD38XjtlOnt70%3D
    • Brem RB, Yvert G, Clinton R, Kruglyak L (2002) Genetic dissection of transcriptional regulation in budding yeast. Science 296:752. doi: 10.1126/science.1069516
    • (2002) Science , vol.296 , pp. 752
    • Brem, R.B.1    Yvert, G.2    Clinton, R.3    Kruglyak, L.4
  • 24
    • 84863981756 scopus 로고    scopus 로고
    • GPSy: A cross-species gene prioritization system for conserved biological processes - Application in male gamete development
    • doi: 10.1093/nar/gks380
    • Britto R, Sallou O, Collin O, Michaux G, Primig M, Chalmel F (2012) GPSy: a cross-species gene prioritization system for conserved biological processes - application in male gamete development. Nucleic Acids Res 40(W1): W458-W465. doi: 10.1093/nar/gks380
    • (2012) Nucleic Acids Res , vol.40
    • Britto, R.1    Sallou, O.2    Collin, O.3    Michaux, G.4    Primig, M.5    Chalmel, F.6
  • 25
    • 20144383240 scopus 로고    scopus 로고
    • Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
    • 10.1038/ng1497 15711547 1:CAS:528:DC%2BD2MXhsFOqurk%3D
    • Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI, Vellenga E et al (2005) Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat Genet 37:225-232. doi: 10.1038/ng1497
    • (2005) Nat Genet , vol.37 , pp. 225-232
    • Bystrykh, L.1    Weersing, E.2    Dontje, B.3    Sutton, S.4    Pletcher, M.T.5    Wiltshire, T.6    Su, A.I.7    Vellenga, E.8
  • 26
    • 65349180167 scopus 로고    scopus 로고
    • Maximal extraction of biological information from genetic interaction data
    • 10.1371/journal.pcbi.1000347 19343223
    • Carter GW, Galas DJ, Galitski T (2009) Maximal extraction of biological information from genetic interaction data. PLoS Comput Biol 5(4):e1000347. doi: 10.1371/journal.pcbi.1000347
    • (2009) PLoS Comput Biol , vol.5 , Issue.4 , pp. 1000347
    • Carter, G.W.1    Galas, D.J.2    Galitski, T.3
  • 27
    • 38049136610 scopus 로고    scopus 로고
    • Improved human disease candidate gene prioritization using mouse phenotype
    • 10.1186/1471-2105-8-392 17939863
    • Chen J, Xu H, Aronow BJ, Jegga AG (2007) Improved human disease candidate gene prioritization using mouse phenotype. BMC Bioinformatics 8:392. doi: 10.1186/1471-2105-8-392
    • (2007) BMC Bioinformatics , vol.8 , pp. 392
    • Chen, J.1    Xu, H.2    Aronow, B.J.3    Jegga, A.G.4
  • 28
    • 72549105714 scopus 로고    scopus 로고
    • Genetic targeting of candidate genes for drought sensitive gene eibi1 of wild barley (Hordeum spontaneum)
    • 10.1270/jsbbs.59.637 1:CAS:528:DC%2BC3cXjvFGiurc%3D
    • Chen G, Pourkheirandish M, Sameri M, Wang N, Nair S, Shi Y, Li C, Nevo E et al (2009a) Genetic targeting of candidate genes for drought sensitive gene eibi1 of wild barley (Hordeum spontaneum). Breeding Sci 59(5):637-644. doi: 10.1270/jsbbs.59.637
    • (2009) Breeding Sci , vol.59 , Issue.5 , pp. 637-644
    • Chen, G.1    Pourkheirandish, M.2    Sameri, M.3    Wang, N.4    Nair, S.5    Shi, Y.6    Li, C.7    Nevo, E.8
  • 29
    • 62849126285 scopus 로고    scopus 로고
    • Disease candidate gene identification and prioritization using protein interaction networks
    • 10.1186/1471-2105-10-73 19245720
    • Chen J, Aronow BJ, Jegga AG (2009b) Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinformatics 10:73. doi: 10.1186/1471-2105-10-73
    • (2009) BMC Bioinformatics , vol.10 , pp. 73
    • Chen, J.1    Aronow, B.J.2    Jegga, A.G.3
  • 30
    • 67849130563 scopus 로고    scopus 로고
    • ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
    • 10.1093/nar/gkp427 19465376 1:CAS:528:DC%2BD1MXosFSrs7g%3D
    • Chen J, Bardes EE, Aronow BJ, Jegga AG (2009c) ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res 37:W305-W311. doi: 10.1093/nar/gkp427
    • (2009) Nucleic Acids Res , vol.37
    • Chen, J.1    Bardes, E.E.2    Aronow, B.J.3    Jegga, A.G.4
  • 31
    • 69549116107 scopus 로고    scopus 로고
    • BreakDancer: An algorithm for high-resolution mapping of genomic structural variation
    • 10.1038/nmeth.1363 1:CAS:528:DC%2BD1MXps1agsrs%3D
    • Chen K, Wallis JW, McLellan MD, Larson DE, Kalicki JM, Pohl CS, McGrath SD, Wendl MC et al (2009d) BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nat Meth 6:677-681. doi: 10.1038/nmeth.1363
    • (2009) Nat Meth , vol.6 , pp. 677-681
    • Chen, K.1    Wallis, J.W.2    McLellan, M.D.3    Larson, D.E.4    Kalicki, J.M.5    Pohl, C.S.6    McGrath, S.D.7    Wendl, M.C.8
  • 32
    • 79952392088 scopus 로고    scopus 로고
    • TargetMine, an integrated data warehouse for candidate gene prioritisation and target discovery
    • 10.1371/journal.pone.0017844 21408081 1:CAS:528:DC%2BC3MXjsFGrs7k%3D
    • Chen YA, Tripathi LP, Mizuguchi K (2011) TargetMine, an integrated data warehouse for candidate gene prioritisation and target discovery. PLoS ONE 6(3):e17844. doi: 10.1371/journal.pone.0017844
    • (2011) PLoS ONE , vol.6 , Issue.3 , pp. 17844
    • Chen, Y.A.1    Tripathi, L.P.2    Mizuguchi, K.3
  • 33
    • 52549103273 scopus 로고    scopus 로고
    • The Collaborative Cross at Oak Ridge National Laboratory: Developing a powerful resource for systems genetics
    • 10.1007/s00335-008-9135-8 18716833
    • Chesler EJ, Miller DR, Branstetter LR, Galloway LD, Jackson BL, Philip VM, Voy BH, Culiat CT et al (2008) The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome 19:382-389. doi: 10.1007/s00335-008-9135-8
    • (2008) Mamm Genome , vol.19 , pp. 382-389
    • Chesler, E.J.1    Miller, D.R.2    Branstetter, L.R.3    Galloway, L.D.4    Jackson, B.L.5    Philip, V.M.6    Voy, B.H.7    Culiat, C.T.8
  • 34
    • 27644482314 scopus 로고    scopus 로고
    • Mapping determinants of human gene expression by regional and genome-wide association
    • 10.1038/nature04244 16251966 1:CAS:528:DC%2BD2MXhtFCrurrN
    • Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT (2005) Mapping determinants of human gene expression by regional and genome-wide association. Nature 437:1365-1369. doi: 10.1038/nature04244
    • (2005) Nature , vol.437 , pp. 1365-1369
    • Cheung, V.G.1    Spielman, R.S.2    Ewens, K.G.3    Weber, T.M.4    Morley, M.5    Burdick, J.T.6
  • 35
    • 62549110860 scopus 로고    scopus 로고
    • Predicting genetic interactions with random walks on biological networks
    • 10.1186/1471-2105-10-17 19138426
    • Chipman KC, Singh AK (2009) Predicting genetic interactions with random walks on biological networks. BMC Bioinformatics 10:17. doi: 10.1186/1471-2105-10-17
    • (2009) BMC Bioinformatics , vol.10 , pp. 17
    • Chipman, K.C.1    Singh, A.K.2
  • 36
    • 78751696689 scopus 로고    scopus 로고
    • Genomic insights into early-onset obesity
    • 10.1186/gm157 20587078
    • Choquet H, Meyre D (2010) Genomic insights into early-onset obesity. Genome Med 2(6):36. doi: 10.1186/gm157
    • (2010) Genome Med , vol.2 , Issue.6 , pp. 36
    • Choquet, H.1    Meyre, D.2
  • 37
    • 78149444304 scopus 로고    scopus 로고
    • Module discovery by exhaustive search for densely connected, co-expressed regions in biomolecular interaction networks
    • 10.1371/journal.pone.0013348 21049092
    • Colak R, Moser F, Chu JS-C, Schönhuth A, Chen N, Ester M (2010) Module discovery by exhaustive search for densely connected, co-expressed regions in biomolecular interaction networks. PLoS ONE 5(10):e13348. doi: 10.1371/journal.pone.0013348
    • (2010) PLoS ONE , vol.5 , Issue.10 , pp. 13348
    • Colak, R.1    Moser, F.2    Chu, J.-C.3    Schönhuth, A.4    Chen, N.5    Ester, M.6
  • 38
    • 77956046092 scopus 로고    scopus 로고
    • Quantitative genetic interaction mapping using the E-MAP approach
    • 10.1016/S0076-6879(10)70009-4 20946812 1:CAS:528:DC%2BC3cXmtFCrt7w%3D
    • Collins SR, Roguev A, Krogan NJ (2010) Quantitative genetic interaction mapping using the E-MAP approach. Methods Enzymol 470:205-231. doi: 10.1016/S0076-6879(10)70009-4
    • (2010) Methods Enzymol , vol.470 , pp. 205-231
    • Collins, S.R.1    Roguev, A.2    Krogan, N.J.3
  • 39
    • 74549130411 scopus 로고    scopus 로고
    • Human synthetic lethal inference as potential anti-cancer target gene detection
    • 10.1186/1752-0509-3-116
    • Conde-Pueyo N, Munteanu A, Solé RV, Rodríguez-Caso C (2009) Human synthetic lethal inference as potential anti-cancer target gene detection. BMC Systems Biol 3:116. doi: 10.1186/1752-0509-3-116
    • (2009) BMC Systems Biol , vol.3 , pp. 116
    • Conde-Pueyo, N.1    Munteanu, A.2    Solé, R.V.3    Rodríguez-Caso, C.4
  • 40
    • 0036010774 scopus 로고    scopus 로고
    • QTL analysis of proteome and transcriptome variations for dissecting the genetic architecture of complex traits in maize
    • 10.1023/A:1014840810203 11999835 1:CAS:528:DC%2BD38XjsFWrtro%3D
    • Consoli L, Lefèvre A, Zivy M, de Vienne D, Damerval C (2002) QTL analysis of proteome and transcriptome variations for dissecting the genetic architecture of complex traits in maize. Plant Mol Biol 48(5-6):575-581. doi: 10.1023/A:1014840810203
    • (2002) Plant Mol Biol , vol.48 , Issue.5-6 , pp. 575-581
    • Consoli, L.1    Lefèvre, A.2    Zivy, M.3    De Vienne, D.4    Damerval, C.5
  • 41
    • 60349092402 scopus 로고    scopus 로고
    • Mapping complex disease traits with global gene expression
    • 10.1038/nrg2537 19223927 1:CAS:528:DC%2BD1MXhvFGlu7g%3D
    • Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M (2009) Mapping complex disease traits with global gene expression. Nat Rev Genet 10:184-194. doi: 10.1038/nrg2537
    • (2009) Nat Rev Genet , vol.10 , pp. 184-194
    • Cookson, W.1    Liang, L.2    Abecasis, G.3    Moffatt, M.4    Lathrop, M.5
  • 42
    • 77954269901 scopus 로고    scopus 로고
    • The GeneMANIA prediction server: Biological network integration for gene prioritization and predicting gene function
    • 10.1093/nar/gkq537
    • David WF, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, Franz M, Grouios C et al (2010) The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res 38:W214-W220. doi: 10.1093/nar/gkq537
    • (2010) Nucleic Acids Res , vol.38
    • David, W.F.1    Donaldson, S.L.2    Comes, O.3    Zuberi, K.4    Badrawi, R.5    Chao, P.6    Franz, M.7    Grouios, C.8
  • 43
    • 20644454887 scopus 로고    scopus 로고
    • Genetical genomics in humans and model organisms
    • 10.1016/j.tig.2005.05.004 15908034
    • de Koning DJ, Haley CS (2005) Genetical genomics in humans and model organisms. Trends Genet 21:377-381. doi: 10.1016/j.tig.2005.05.004
    • (2005) Trends Genet , vol.21 , pp. 377-381
    • De Koning, D.J.1    Haley, C.S.2
  • 44
    • 44449135980 scopus 로고    scopus 로고
    • Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles
    • 10.1073/pnas.0710533105 18408161 1:CAS:528:DC%2BD1cXltVOqtbc%3D
    • Decourty L, Saveanu C, Zemam K, Hantraye F, Frachon E, Rousselle JC, Fromont-Racine M, Jacquier A (2008) Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles. Proc Natl Acad Sci USA 105(15):5821-5826. doi: 10.1073/pnas.0710533105
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.15 , pp. 5821-5826
    • Decourty, L.1    Saveanu, C.2    Zemam, K.3    Hantraye, F.4    Frachon, E.5    Rousselle, J.C.6    Fromont-Racine, M.7    Jacquier, A.8
  • 45
    • 77249134594 scopus 로고    scopus 로고
    • Rare variants create synthetic genome-wide associations
    • 10.1371/journal.pbio.1000294
    • Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB (2011) Rare variants create synthetic genome-wide associations. PLoS Biol 9:e1001008. doi: 10.1371/journal.pbio.1000294
    • (2011) PLoS Biol , vol.9 , pp. 1001008
    • Dickson, S.P.1    Wang, K.2    Krantz, I.3    Hakonarson, H.4    Goldstein, D.B.5
  • 46
  • 47
    • 19844366096 scopus 로고    scopus 로고
    • Cis-acting expression quantitative trait loci in mice
    • 10.1101/gr.3216905 15837804 1:CAS:528:DC%2BD2MXkt1Clt7c%3D
    • Doss S, Schadt EE, Drake TA, Lusis AJ (2005) Cis-acting expression quantitative trait loci in mice. Genome Res 15:681-691. doi: 10.1101/gr.3216905
    • (2005) Genome Res , vol.15 , pp. 681-691
    • Doss, S.1    Schadt, E.E.2    Drake, T.A.3    Lusis, A.J.4
  • 48
    • 79953200487 scopus 로고    scopus 로고
    • High-confidence discovery of genetic network regulators in expression quantitative trait loci data
    • 10.1534/genetics.110.124685 21212238 1:CAS:528:DC%2BC3MXmsVSgsLg%3D
    • Duarte CW, Zeng ZB (2011) High-confidence discovery of genetic network regulators in expression quantitative trait loci data. Genetics 187:955-964. doi: 10.1534/genetics.110.124685
    • (2011) Genetics , vol.187 , pp. 955-964
    • Duarte, C.W.1    Zeng, Z.B.2
  • 49
  • 50
    • 34748850690 scopus 로고    scopus 로고
    • Pinpointing expression differences
    • Editorial doi: 10.1038/ng1007-1175
    • Editorial (2007) Pinpointing expression differences. Nat Genet 39:1175.doi: 10.1038/ng1007-1175
    • (2007) Nat Genet , vol.39 , pp. 1175
  • 52
    • 79959464683 scopus 로고    scopus 로고
    • DADA: Degree-aware algorithms for network-based disease gene prioritization
    • 10.1186/1756-0381-4-19 21699738
    • Erten S, Bebek G, Ewing RM, Koyutürk M (2011a) DADA: degree-aware algorithms for network-based disease gene prioritization. BioData Mining 4:19. doi: 10.1186/1756-0381-4-19
    • (2011) BioData Mining , vol.4 , pp. 19
    • Erten, S.1    Bebek, G.2    Ewing, R.M.3    Koyutürk, M.4
  • 53
    • 80955159942 scopus 로고    scopus 로고
    • Vavien: An algorithm for prioritizing candidate disease genes based on topological similarity of proteins in interaction networks
    • 10.1089/cmb.2011.0154 22035267 1:CAS:528:DC%2BC3MXhsFyqsLjM
    • Erten S, Bebek G, Koyutürk M (2011b) Vavien: an algorithm for prioritizing candidate disease genes based on topological similarity of proteins in interaction networks. J Comput Biol 18(11):1561-1574. doi: 10.1089/cmb.2011.0154
    • (2011) J Comput Biol , vol.18 , Issue.11 , pp. 1561-1574
    • Erten, S.1    Bebek, G.2    Koyutürk, M.3
  • 55
    • 33646884801 scopus 로고    scopus 로고
    • Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes
    • 16685651 1:CAS:528:DC%2BD28XltVyks70%3D
    • Franke L, Bakel H, Fokkens L, de Jong ED, Egmont-Petersen M, Wijmenga C (2006) Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes. Am J Hum Genet 78:1011-1025
    • (2006) Am J Hum Genet , vol.78 , pp. 1011-1025
    • Franke, L.1    Bakel, H.2    Fokkens, L.3    De Jong, E.D.4    Egmont-Petersen, M.5    Wijmenga, C.6
  • 57
    • 54549103518 scopus 로고    scopus 로고
    • Prioritization of candidate cancer genes - An aid to oncogenomic studies
    • 10.1093/nar/gkn482 18710882
    • Furney SJ, Calvo B, Larrañaga P, Lozano JA, Lopez-Bigas N (2008) Prioritization of candidate cancer genes - an aid to oncogenomic studies. Nucleic Acids Res 36(18):e115. doi: 10.1093/nar/gkn482
    • (2008) Nucleic Acids Res , vol.36 , Issue.18 , pp. 115
    • Furney, S.J.1    Calvo, B.2    Larrañaga, P.3    Lozano, J.A.4    Lopez-Bigas, N.5
  • 59
    • 60149097209 scopus 로고    scopus 로고
    • FastMap: Fast eQTL mapping in homozygous populations
    • 10.1093/bioinformatics/btn648 19091771 1:CAS:528:DC%2BD1MXhvF2msb0%3D
    • Gatti DM, Shabalin AA, Lam TC, Wright FA, Rusyn I, Nobel AB (2009) FastMap: fast eQTL mapping in homozygous populations. Bioinformatics 25(4):482-489. doi: 10.1093/bioinformatics/btn648
    • (2009) Bioinformatics , vol.25 , Issue.4 , pp. 482-489
    • Gatti, D.M.1    Shabalin, A.A.2    Lam, T.C.3    Wright, F.A.4    Rusyn, I.5    Nobel, A.B.6
  • 60
    • 4143093624 scopus 로고    scopus 로고
    • Bridge-PLS regression: Two-block bilinear regression without deflation
    • 10.1002/cem.862 1:CAS:528:DC%2BD2cXnt1Wgt74%3D
    • Gidskehaug L, Stødkilde-Jørgensen H, Martens M, Martens H (2004) Bridge-PLS regression: two-block bilinear regression without deflation. J Chemometr 18:208-215. doi: 10.1002/cem.862
    • (2004) J Chemometr , vol.18 , pp. 208-215
    • Gidskehaug, L.1    Stødkilde-Jørgensen, H.2    Martens, M.3    Martens, H.4
  • 61
    • 84856171382 scopus 로고    scopus 로고
    • Targeting Rb inactivation in cancers by synthetic lethality
    • 21814623
    • Gordon GM, Du W (2011) Targeting Rb inactivation in cancers by synthetic lethality. Am J Cancer Res 1(6):773-786
    • (2011) Am J Cancer Res , vol.1 , Issue.6 , pp. 773-786
    • Gordon, G.M.1    Du, W.2
  • 63
    • 74049131900 scopus 로고    scopus 로고
    • Genetic risk information for common diseases may indeed be already useful for prevention and early detection
    • 10.1111/j.1365-2362.2009.02233.x 20055896 1:STN:280: DC%2BC3c%2Fht1ertw%3D%3D
    • Gulcher J, Stefansson K (2010) Genetic risk information for common diseases may indeed be already useful for prevention and early detection. Eur J Clin Invest 40(1):56-63. doi: 10.1111/j.1365-2362.2009.02233.x
    • (2010) Eur J Clin Invest , vol.40 , Issue.1 , pp. 56-63
    • Gulcher, J.1    Stefansson, K.2
  • 64
    • 77952003027 scopus 로고    scopus 로고
    • Using association mapping to dissect the genetic basis of complex traits in plants
    • 10.1093/bfgp/elp048 1:CAS:528:DC%2BC3cXjvF2hu7o%3D
    • Hall D, Tegström C, Ingvarsson PK (2010) Using association mapping to dissect the genetic basis of complex traits in plants. Brief in Funct Genomics 9(2):157-165. doi: 10.1093/bfgp/elp048
    • (2010) Brief in Funct Genomics , vol.9 , Issue.2 , pp. 157-165
    • Hall, D.1    Tegström, C.2    Ingvarsson, P.K.3
  • 65
    • 39849095692 scopus 로고    scopus 로고
    • Identifying the molecular basis of QTLs: EQTLs add a new dimension
    • 10.1016/j.tplants.2007.11.008 18262820 1:CAS:528:DC%2BD1cXivVOntbY%3D
    • Hansen BG, Halkier BA, Kliebenstein DJ (2008) Identifying the molecular basis of QTLs: eQTLs add a new dimension. Trends Plant Sci 13:72-77. doi: 10.1016/j.tplants.2007.11.008
    • (2008) Trends Plant Sci , vol.13 , pp. 72-77
    • Hansen, B.G.1    Halkier, B.A.2    Kliebenstein, D.J.3
  • 67
    • 77955886707 scopus 로고    scopus 로고
    • Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP Ribose) polymerase inhibitors in ovarian cancer
    • 10.1200/JCO.2009.27.2997 20606085
    • Hennessy BTJ, Timms KM, Carey MS, Gutin A, Meyer LA, Flake DD II, Abkevich V, Potter J et al (2010) Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP Ribose) polymerase inhibitors in ovarian cancer. J Clin Oncol 28(22):3570-3576. doi: 10.1200/JCO.2009.27.2997
    • (2010) J Clin Oncol , vol.28 , Issue.22 , pp. 3570-3576
    • Hennessy, B.T.J.1    Timms, K.M.2    Carey, M.S.3    Gutin, A.4    Meyer, L.A.5    Flake, I.I.D.D.6    Abkevich, V.7    Potter, J.8
  • 68
    • 75449111415 scopus 로고    scopus 로고
    • Understanding and using quantitative genetic variation
    • 10.1098/rstb.2009.0203 20008387
    • Hill WG (2010) Understanding and using quantitative genetic variation. Phil Trans R Soc B 365:73-85. doi: 10.1098/rstb.2009.0203
    • (2010) Phil Trans R Soc B , vol.365 , pp. 73-85
    • Hill, W.G.1
  • 69
    • 84865326984 scopus 로고    scopus 로고
    • A semantic web framework to integrate cancer omics data with biological knowledge
    • 10.1186/1471-2105-13-S1-S10 22373303
    • Holford ME, McCusker JP, Cheung KH, Krauthammer M (2012) A semantic web framework to integrate cancer omics data with biological knowledge. BMC Bioinformatics 13(Suppl 1):S10. doi: 10.1186/1471-2105-13-S1-S10
    • (2012) BMC Bioinformatics , vol.13 , Issue.SUPPL. 1 , pp. 10
    • Holford, M.E.1    McCusker, J.P.2    Cheung, K.H.3    Krauthammer, M.4
  • 70
    • 67650064593 scopus 로고    scopus 로고
    • Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes
    • 10.1101/gr.088633.108 19447966 1:CAS:528:DC%2BD1MXosVCktbo%3D
    • Hormozdiari F, Alkan C, Eichler EE, Sahinalp SC (2009) Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes. Genome Res 19:1270-1278. doi: 10.1101/gr.088633.108
    • (2009) Genome Res , vol.19 , pp. 1270-1278
    • Hormozdiari, F.1    Alkan, C.2    Eichler, E.E.3    Sahinalp, S.C.4
  • 71
    • 79953289737 scopus 로고    scopus 로고
    • Mapping of signaling networks through synthetic genetic interaction analysis by RNAi
    • 10.1038/nmeth.1581 21378980 1:CAS:528:DC%2BC3MXivVSnsLc%3D
    • Horn T, Sandmann T, Fischer B, Axelsson E, Huber W, Boutros M (2011) Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. Nat Methods 8:341-346. doi: 10.1038/nmeth.1581
    • (2011) Nat Methods , vol.8 , pp. 341-346
    • Horn, T.1    Sandmann, T.2    Fischer, B.3    Axelsson, E.4    Huber, W.5    Boutros, M.6
  • 72
    • 84864035642 scopus 로고    scopus 로고
    • A quantitative analysis of monochromaticity in genetic interaction networks
    • 10.1186/1471-2105-12-S13-S16 22372977
    • Hsu CH, Wang TY, Chu HT, Kao CY, Chen KC (2011) A quantitative analysis of monochromaticity in genetic interaction networks. BMC Bioinformatics 12(Suppl 13):S16. doi: 10.1186/1471-2105-12-S13-S16
    • (2011) BMC Bioinformatics , vol.12 , Issue.SUPPL. 13 , pp. 16
    • Hsu, C.H.1    Wang, T.Y.2    Chu, H.T.3    Kao, C.Y.4    Chen, K.C.5
  • 73
    • 84873712924 scopus 로고    scopus 로고
    • Gene network modular-based classification of microarray samples
    • 10.1186/1471-2105-13-S10-S17 22759422
    • Hu P, Bull SB, Jiang H (2012) Gene network modular-based classification of microarray samples. BMC Bioinformatics 13(Suppl 10):S17. doi: 10.1186/1471-2105-13-S10-S17
    • (2012) BMC Bioinformatics , vol.13 , Issue.SUPPL. 10 , pp. 17
    • Hu, P.1    Bull, S.B.2    Jiang, H.3
  • 74
    • 32644435468 scopus 로고    scopus 로고
    • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer
    • 10.1093/nar/gkj468 16432260 1:CAS:528:DC%2BD28XhtlOnu7s%3D
    • Huang Z, Wen Y, Shandilya R, Marks JR, Berchuck A, Murphy SK (2006) High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. Nucleic Acids Res 34(2):555-563. doi: 10.1093/nar/gkj468
    • (2006) Nucleic Acids Res , vol.34 , Issue.2 , pp. 555-563
    • Huang, Z.1    Wen, Y.2    Shandilya, R.3    Marks, J.R.4    Berchuck, A.5    Murphy, S.K.6
  • 75
    • 79961193344 scopus 로고    scopus 로고
    • EResponseNet: A package prioritizing candidate disease genes through cellular pathways
    • 10.1093/bioinformatics/btr380 21700671 1:CAS:528:DC%2BC3MXhtVSiurnP
    • Huang J, Liu Y, Zhang W, Yu H, Han JDJ (2011) eResponseNet: a package prioritizing candidate disease genes through cellular pathways. Bioinformatics 27(16):2319-2320. doi: 10.1093/bioinformatics/btr380
    • (2011) Bioinformatics , vol.27 , Issue.16 , pp. 2319-2320
    • Huang, J.1    Liu, Y.2    Zhang, W.3    Yu, H.4    Han, J.D.J.5
  • 76
    • 20144377218 scopus 로고    scopus 로고
    • Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
    • 10.1038/ng1522 15711544 1:CAS:528:DC%2BD2MXhsFOqu7c%3D
    • Hubner N, Wallace CA, Zimdahl H, Petretto E, Schulz H, Maciver F, Mueller M, Hummel O et al (2005) Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet 37:243-253. doi: 10.1038/ng1522
    • (2005) Nat Genet , vol.37 , pp. 243-253
    • Hubner, N.1    Wallace, C.A.2    Zimdahl, H.3    Petretto, E.4    Schulz, H.5    MacIver, F.6    Mueller, M.7    Hummel, O.8
  • 77
    • 44249093758 scopus 로고    scopus 로고
    • Advances in the molecular diagnosis and prognosis of colorectal cancer: CRC prognosis
    • 18598107 1:CAS:528:DC%2BD1cXlvFyns78%3D
    • Huerta S (2008) Advances in the molecular diagnosis and prognosis of colorectal cancer: CRC prognosis. Expert Rev Mol Diagn 8(3):277-288
    • (2008) Expert Rev Mol Diagn , vol.8 , Issue.3 , pp. 277-288
    • Huerta, S.1
  • 78
    • 57349142898 scopus 로고    scopus 로고
    • Nonparametric estimation of LOH using Affymetrix SNP genotyping arrays for unpaired samples
    • 10.1007/s10038-008-0340-9
    • Huggins R, Li LH, Lin YC, Yu AL, Yang HC (2008) Nonparametric estimation of LOH using Affymetrix SNP genotyping arrays for unpaired samples. J Human Genet 53(11-12):983-990. doi: 10.1007/s10038-008-0340-9
    • (2008) J Human Genet , vol.53 , Issue.11-12 , pp. 983-990
    • Huggins, R.1    Li, L.H.2    Lin, Y.C.3    Yu, A.L.4    Yang, H.C.5
  • 80
    • 79958811515 scopus 로고    scopus 로고
    • Associations of polymorphisms in HPC2/ELAC2 and SRD5A2 genes with benign prostate hyperplasia in turkish men
    • Izmirli M, Arikan B, Bayazit Y, Alptekin D (2011) Associations of polymorphisms in HPC2/ELAC2 and SRD5A2 genes with benign prostate hyperplasia in turkish men. Asian Pacific J Cancer Prev 12:731-733
    • (2011) Asian Pacific J Cancer Prev , vol.12 , pp. 731-733
    • Izmirli, M.1    Arikan, B.2    Bayazit, Y.3    Alptekin, D.4
  • 81
    • 0035400051 scopus 로고    scopus 로고
    • Genetical genomics: The added value from segregation
    • 10.1016/S0168-9525(01)02310-1 11418218 1:CAS:528:DC%2BD3MXksVyntLo%3D
    • Jansen RC, Nap JP (2001) Genetical genomics: the added value from segregation. Trends Genet 17:388-391. doi: 10.1016/S0168-9525(01)02310-1
    • (2001) Trends Genet , vol.17 , pp. 388-391
    • Jansen, R.C.1    Nap, J.P.2
  • 82
    • 0142052944 scopus 로고    scopus 로고
    • A Bayesian networks approach for predicting protein-protein interactions from genomic data
    • 10.1126/science.1087361 14564010 1:CAS:528:DC%2BD3sXotV2itr8%3D
    • Jansen R, Yu H, Greenbaum D, Kluger Y, Krogan NJ, Chung S, Emili A, Snyder M et al (2003) A Bayesian networks approach for predicting protein-protein interactions from genomic data. Science 302(5644):449-453. doi: 10.1126/science.1087361
    • (2003) Science , vol.302 , Issue.5644 , pp. 449-453
    • Jansen, R.1    Yu, H.2    Greenbaum, D.3    Kluger, Y.4    Krogan, N.J.5    Chung, S.6    Emili, A.7    Snyder, M.8
  • 83
    • 57649243614 scopus 로고    scopus 로고
    • Genome-based prediction of common diseases: Advances and prospects
    • (R2) doi: 10.1093/hmg/ddn250
    • Janssens AC, van Duijn CM (2008) Genome-based prediction of common diseases: advances and prospects. Hum Mol Genet 17(R2):R166-R173.doi: 10.1093/hmg/ddn250
    • (2008) Hum Mol Genet , vol.17
    • Janssens, A.C.1    Van Duijn, C.M.2
  • 84
    • 53749091787 scopus 로고    scopus 로고
    • Predicting quantitative genetic interactions by means of sequential matrix approximation
    • 10.1371/journal.pone.0003284 18818762
    • Järvinen AP, Hiissa J, Elo LL, Aittokallio T (2008) Predicting quantitative genetic interactions by means of sequential matrix approximation. PLoS ONE 3(9):e3284. doi: 10.1371/journal.pone.0003284
    • (2008) PLoS ONE , vol.3 , Issue.9 , pp. 3284
    • Järvinen, A.P.1    Hiissa, J.2    Elo, L.L.3    Aittokallio, T.4
  • 85
    • 69249240178 scopus 로고    scopus 로고
    • The combined status of ATM and p53 link tumor development with therapeutic response
    • 10.1101/gad.1815309 1:CAS:528:DC%2BD1MXhtVegurbO
    • Jiang H, Reinhardt HC, Bartkova J, Tommiska J, Blomqvist C, Nevanlinna H, Bartek J, Yaffe MB et al (2009) The combined status of ATM and p53 link tumor development with therapeutic response. Genes & Dev 23:1895-1909. doi: 10.1101/gad.1815309
    • (2009) Genes & Dev , vol.23 , pp. 1895-1909
    • Jiang, H.1    Reinhardt, H.C.2    Bartkova, J.3    Tommiska, J.4    Blomqvist, C.5    Nevanlinna, H.6    Bartek, J.7    Yaffe, M.B.8
  • 86
  • 87
    • 79955578524 scopus 로고    scopus 로고
    • Genomics in the post-GWAS era
    • 10.1055/s-0031-1276641 21538286
    • Juran BD, Lazaridis KN (2011) Genomics in the post-GWAS era. Semin Liver Dis 31(2):215-222. doi: 10.1055/s-0031-1276641
    • (2011) Semin Liver Dis , vol.31 , Issue.2 , pp. 215-222
    • Juran, B.D.1    Lazaridis, K.N.2
  • 88
    • 33645068841 scopus 로고    scopus 로고
    • Statistical methods for expression quantitative trait loci (eQTL) mapping
    • 10.1111/j.1541-0420.2005.00437.x 16542225 1:STN:280: DC%2BD287ltlWntQ%3D%3D
    • Kendziorski CM, Chen M, Yuan M, Lan H, Attie AD (2006) Statistical methods for expression quantitative trait loci (eQTL) mapping. Biometrics 62(1):19-27. doi: 10.1111/j.1541-0420.2005.00437.x
    • (2006) Biometrics , vol.62 , Issue.1 , pp. 19-27
    • Kendziorski, C.M.1    Chen, M.2    Yuan, M.3    Lan, H.4    Attie, A.D.5
  • 89
    • 62349101060 scopus 로고    scopus 로고
    • Genetical metabolomics: Closing in on phenotypes
    • 10.1016/j.pbi.2008.12.003 19162531 1:CAS:528:DC%2BD1MXjsVOgur0%3D
    • Keurentjes JJB (2009) Genetical metabolomics: closing in on phenotypes. Curr Opin Plant Biol 12:223-230. doi: 10.1016/j.pbi.2008.12.003
    • (2009) Curr Opin Plant Biol , vol.12 , pp. 223-230
    • Keurentjes, J.J.B.1
  • 91
    • 33846818896 scopus 로고    scopus 로고
    • Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci
    • 10.1073/pnas.0610429104 17237218 1:CAS:528:DC%2BD2sXhslGjt7k%3D
    • Keurentjes JJ, Fu J, Terpstra IR, Garcia JM, Ackerveken G, Snoek LB, Peeters AJ, Vreugdenhil D et al (2007) Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci. Proc Natl Acad Sci USA 104:1708-1713. doi: 10.1073/pnas.0610429104
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1708-1713
    • Keurentjes, J.J.1    Fu, J.2    Terpstra, I.R.3    Garcia, J.M.4    Ackerveken, G.5    Snoek, L.B.6    Peeters, A.J.7    Vreugdenhil, D.8
  • 92
    • 41149122980 scopus 로고    scopus 로고
    • Quantitative genetics in the age of omics
    • 10.1016/j.pbi.2008.01.006 18325828 1:CAS:528:DC%2BD1cXktFCmsr0%3D
    • Keurentjes JJB, Koornneef M, Vreugdenhil D (2008) Quantitative genetics in the age of omics. Curr Opin Plant Biol 11:123-128. doi: 10.1016/j.pbi.2008. 01.006
    • (2008) Curr Opin Plant Biol , vol.11 , pp. 123-128
    • Keurentjes, J.J.B.1    Koornneef, M.2    Vreugdenhil, D.3
  • 93
    • 84873736127 scopus 로고    scopus 로고
    • Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene and predisposition to colorectal cancer: Significant association in colorectal cancer patients of Kashmir
    • 10.5897/JCREO11.033 1:CAS:528:DC%2BC3MXhs1KhtbrO
    • Khan NP, Pandith AA, Hussain MUI, Yousuf A, Khan MS, Siddiqi MA, Wani KA, Mudassar S (2011) Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene and predisposition to colorectal cancer: Significant association in colorectal cancer patients of Kashmir. J Cancer Res Exp Oncol 3(8):88-94. doi: 10.5897/JCREO11.033
    • (2011) J Cancer Res Exp Oncol , vol.3 , Issue.8 , pp. 88-94
    • Khan, N.P.1    Pandith, A.A.2    Hussain, M.U.I.3    Yousuf, A.4    Khan, M.S.5    Siddiqi, M.A.6    Wani, K.A.7    Mudassar, S.8
  • 94
    • 84873707569 scopus 로고    scopus 로고
    • An enhanced dimension reduction approach for microarray gene expression data
    • doi: 10.4051/ibc.2009.4.0013
    • Kim S, Lee H (2009) An enhanced dimension reduction approach for microarray gene expression data. Interdiscip Bio Central 1(13):1-6. doi: 10.4051/ibc.2009.4.0013
    • (2009) Interdiscip Bio Central , vol.1 , Issue.13 , pp. 1-6
    • Kim, S.1    Lee, H.2
  • 95
    • 33847257936 scopus 로고    scopus 로고
    • Indelign: A probabilistic framework for annotation of insertions and deletions in a multiple alignment
    • 10.1093/bioinformatics/btl578 17110370 1:CAS:528:DC%2BD2sXhtlOltLY%3D
    • Kim I, Sinha S (2007) Indelign: a probabilistic framework for annotation of insertions and deletions in a multiple alignment. Bioinformatics 23:289-297. doi: 10.1093/bioinformatics/btl578
    • (2007) Bioinformatics , vol.23 , pp. 289-297
    • Kim, I.1    Sinha, S.2
  • 96
    • 84873739007 scopus 로고    scopus 로고
    • Directed causal network construction using linkage analysis with metabolic syndrome-related expression quantitative traits
    • 10.5808/GI.2011.9.4.143
    • Kim KZ, Min JY, Kwon GY, Sung J, Cho S (2011) Directed causal network construction using linkage analysis with metabolic syndrome-related expression quantitative traits. Genom Inform 9(4):143-151. doi: 10.5808/GI.2011.9.4.143
    • (2011) Genom Inform , vol.9 , Issue.4 , pp. 143-151
    • Kim, K.Z.1    Min, J.Y.2    Kwon, G.Y.3    Sung, J.4    Cho, S.5
  • 97
    • 84856220373 scopus 로고    scopus 로고
    • Quantification of protein interaction in living cells by two-photon spectral imaging with fluorescent protein fluorescence resonance energy transfer pair devoid of acceptor bleed-through
    • 10.1002/cyto.a.21150 1:CAS:528:DC%2BC38XhtFShtro%3D
    • Kim J, Li X, Kang MS, Im KB, Genovesio A, Grailhe R (2012) Quantification of protein interaction in living cells by two-photon spectral imaging with fluorescent protein fluorescence resonance energy transfer pair devoid of acceptor bleed-through. Cytometry Part A 81A(2):112-119. doi: 10.1002/cyto.a.21150
    • (2012) Cytometry Part A , vol.81 , Issue.2 , pp. 112-119
    • Kim, J.1    Li, X.2    Kang, M.S.3    Im, K.B.4    Genovesio, A.5    Grailhe, R.6
  • 98
    • 69949161748 scopus 로고    scopus 로고
    • Advancing genetic theory and application by metabolic quantitative trait loci analysis
    • 10.1105/tpc.109.067611 19525414 1:CAS:528:DC%2BD1MXpvFOksrs%3D
    • Kliebenstein DJ (2009a) Advancing genetic theory and application by metabolic quantitative trait loci analysis. Plant Cell 21:1637-1646. doi: 10.1105/tpc.109.067611
    • (2009) Plant Cell , vol.21 , pp. 1637-1646
    • Kliebenstein, D.J.1
  • 99
    • 73949102041 scopus 로고    scopus 로고
    • Quantification of variation in expression networks
    • 10.1007/978-1-60327-563-7-11 19588108 1:CAS:528:DC%2BC3cXhvFWks7Y%3D
    • Kliebenstein DJ (2009b) Quantification of variation in expression networks. Methods Mol Biol 553:227-245. doi: 10.1007/978-1-60327-563-7-11
    • (2009) Methods Mol Biol , vol.553 , pp. 227-245
    • Kliebenstein, D.J.1
  • 100
    • 66449127752 scopus 로고    scopus 로고
    • Quantitative genomics: Analyzing intraspecific variation using global gene expression polymorphisms or eQTLs
    • 1:CAS:528:DC%2BD1MXntFGls74%3D
    • Kliebenstein D (2009c) Quantitative genomics: analyzing intraspecific variation using global gene expression polymorphisms or eQTLs. Ann Rev Plant Biol 60:93-114
    • (2009) Ann Rev Plant Biol , vol.60 , pp. 93-114
    • Kliebenstein, D.1
  • 101
    • 75949084606 scopus 로고    scopus 로고
    • Systems biology uncovers the foundation of natural genetic diversity
    • 10.1104/pp.109.149328 19933384 1:CAS:528:DC%2BC3cXmsFegsb0%3D
    • Kliebenstein DJ (2010) Systems biology uncovers the foundation of natural genetic diversity. Plant Physiol 152(2):480-486. doi: 10.1104/pp.109.149328
    • (2010) Plant Physiol , vol.152 , Issue.2 , pp. 480-486
    • Kliebenstein, D.J.1
  • 102
    • 69949122158 scopus 로고    scopus 로고
    • VarScan: Variant detection in massively parallel sequencing of individual and pooled samples
    • 10.1093/bioinformatics/btp373
    • Kobolt DC, Chen K, Wylie T, Larson DE, McLellan MD, Mardis ER, Weinstock GM et al (2009) VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics 25:2283-2285. doi: 10.1093/bioinformatics/btp373
    • (2009) Bioinformatics , vol.25 , pp. 2283-2285
    • Kobolt, D.C.1    Chen, K.2    Wylie, T.3    Larson, D.E.4    McLellan, M.D.5    Mardis, E.R.6    Weinstock, G.M.7
  • 103
    • 35348988679 scopus 로고    scopus 로고
    • Paired-end mapping reveals extensive structural variation in the human genome
    • 10.1126/science.1149504 17901297 1:CAS:528:DC%2BD2sXhtFOjtbzL
    • Korbel JO, Urban AE, Affourtit JP, Godwin B, Grubert F, Simons JF, Kim PM, Palejev D et al (2007) Paired-end mapping reveals extensive structural variation in the human genome. Science 318:420-426. doi: 10.1126/science.1149504
    • (2007) Science , vol.318 , pp. 420-426
    • Korbel, J.O.1    Urban, A.E.2    Affourtit, J.P.3    Godwin, B.4    Grubert, F.5    Simons, J.F.6    Kim, P.M.7    Palejev, D.8
  • 104
    • 62549131646 scopus 로고    scopus 로고
    • PEMer: A computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data
    • 10.1186/gb-2009-10-2-r23
    • Korbel JO, Abyzov A, Mu XJ, Carriero N, Cayting P, Zhang Z, Snyder M, Gerstein MB (2009) PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data. Genom Biol 10:R23. doi: 10.1186/gb-2009-10-2-r23
    • (2009) Genom Biol , vol.10 , pp. 23
    • Korbel, J.O.1    Abyzov, A.2    Mu, X.J.3    Carriero, N.4    Cayting, P.5    Zhang, Z.6    Snyder, M.7    Gerstein, M.B.8
  • 105
    • 65949099120 scopus 로고    scopus 로고
    • Genetic risk prediction - Are we there yet?
    • 10.1056/NEJMp0810107 19369656 1:CAS:528:DC%2BD1MXkvVOnu7Y%3D
    • Kraft P, Hunter DJ (2009) Genetic risk prediction - are we there yet? N Engl J Med 360(17):1701-1703. doi: 10.1056/NEJMp0810107
    • (2009) N Engl J Med , vol.360 , Issue.17 , pp. 1701-1703
    • Kraft, P.1    Hunter, D.J.2
  • 106
    • 78650204347 scopus 로고    scopus 로고
    • Exploration of synthetic lethal interactions as cancer drug targets
    • 10.2217/fon.10.131 21142664 1:CAS:528:DC%2BC3cXhsFeqt7fI
    • Kuiken HJ, Beijersbergen RL (2010) Exploration of synthetic lethal interactions as cancer drug targets. Future Oncol 6(11):1789-1802. doi: 10.2217/fon.10.131
    • (2010) Future Oncol , vol.6 , Issue.11 , pp. 1789-1802
    • Kuiken, H.J.1    Beijersbergen, R.L.2
  • 107
    • 74049093136 scopus 로고    scopus 로고
    • Nucleotide-resolution analysis of structural variants using Breakseq and a breakpoint library
    • doi: 10.1038/nbt.1600
    • Lam HYK, Mu XJ, Stütz AM, Tanzer A, Cayting PD, Snyder M, Kim PM, Korbel JO, Gerstein MB (2010) Nucleotide-resolution analysis of structural variants using Breakseq and a breakpoint library. Nat Biotechnol 28:47-55. doi: 10.1038/nbt.1600
    • (2010) Nat Biotechnol , vol.28 , pp. 47-55
    • Lam Hyk, M.1
  • 108
    • 67649580757 scopus 로고    scopus 로고
    • MoDIL: Detecting small indels from clone-end sequencing with mixtures of distributions
    • 10.1038/nmeth.f.256 1:CAS:528:DC%2BD1MXms1aks7c%3D
    • Lee S, Hormozdiari F, Alkan C, Brudno M (2009) MoDIL: detecting small indels from clone-end sequencing with mixtures of distributions. Nat Meth 6:473-474. doi: 10.1038/nmeth.f.256
    • (2009) Nat Meth , vol.6 , pp. 473-474
    • Lee, S.1    Hormozdiari, F.2    Alkan, C.3    Brudno, M.4
  • 109
    • 27744476660 scopus 로고    scopus 로고
    • Genetical genomics: Combining genetics with gene expression analysis
    • (Spec No 2) doi: 10.1093/hmg/ddi267
    • Li J, Burmeister M (2005) Genetical genomics: combining genetics with gene expression analysis. Hum Mol Genet 14(Spec No 2):R163-R169. doi: 10.1093/hmg/ddi267
    • (2005) Hum Mol Genet , vol.14
    • Li, J.1    Burmeister, M.2
  • 110
    • 77957374321 scopus 로고    scopus 로고
    • Systems genetics, bioinformatics and eQTL mapping
    • 10.1007/s10709-010-9480-x 20811929
    • Li H, Deng H (2010) Systems genetics, bioinformatics and eQTL mapping. Genetica 138:915-924. doi: 10.1007/s10709-010-9480-x
    • (2010) Genetica , vol.138 , pp. 915-924
    • Li, H.1    Deng, H.2
  • 111
    • 84859821844 scopus 로고    scopus 로고
    • Systems genetics: Challenges and developing strategies
    • 10.2478/s11756-012-0026-9
    • Li H, Zhang P (2012) Systems genetics: challenges and developing strategies. Biologia 67(3):435-446. doi: 10.2478/s11756-012-0026-9
    • (2012) Biologia , vol.67 , Issue.3 , pp. 435-446
    • Li, H.1    Zhang, P.2
  • 112
    • 33845976693 scopus 로고    scopus 로고
    • Mapping determinants of gene expression plasticity by genetical genomics in C. elegans
    • 10.1371/journal.pgen.0020222 17196041
    • Li Y, Alvarez OA, Gutteling EW, Tijsterman M, Fu J, Risken JAG, Hazendonk E, Prins P et al (2006) Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. PLoS Genet 2:e222. doi: 10.1371/journal.pgen. 0020222
    • (2006) PLoS Genet , vol.2 , pp. 222
    • Li, Y.1    Alvarez, O.A.2    Gutteling, E.W.3    Tijsterman, M.4    Fu, J.5    Risken, J.A.G.6    Hazendonk, E.7    Prins, P.8
  • 113
    • 55549097836 scopus 로고    scopus 로고
    • Mapping short DNA sequencing reads and calling variants using mapping quality scores
    • 10.1101/gr.0788212.108 18714091 1:CAS:528:DC%2BD1cXhtlKhsrrN
    • Li H, Ruan J, Durbin R (2008a) Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res 18:1851-1858. doi: 10.1101/gr.0788212.108
    • (2008) Genome Res , vol.18 , pp. 1851-1858
    • Li, H.1    Ruan, J.2    Durbin, R.3
  • 114
    • 52949116045 scopus 로고    scopus 로고
    • Generalizing genetical genomics: Getting added value from environmental perturbation
    • 10.1016/j.tig.2008.08.001 18774198
    • Li Y, Breitling R, Jansen RC (2008b) Generalizing genetical genomics: getting added value from environmental perturbation. Trends Genet 24:518-524. doi: 10.1016/j.tig.2008.08.001
    • (2008) Trends Genet , vol.24 , pp. 518-524
    • Li, Y.1    Breitling, R.2    Jansen, R.C.3
  • 115
    • 78049323331 scopus 로고    scopus 로고
    • Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
    • 10.1038/ng.680 20890277 1:CAS:528:DC%2BC3cXht1elu7rP
    • Li Y, Vinckenbosch N, Tian G, Huerta-Sanchez E, Jiang T, Jiang H, Albrechtsen A, Andersen G et al (2010) Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet 42:969-972. doi: 10.1038/ng.680
    • (2010) Nat Genet , vol.42 , pp. 969-972
    • Li, Y.1    Vinckenbosch, N.2    Tian, G.3    Huerta-Sanchez, E.4    Jiang, T.5    Jiang, H.6    Albrechtsen, A.7    Andersen, G.8
  • 116
    • 79957519721 scopus 로고    scopus 로고
    • Brain eQTL mapping informs genetic studies of psychiatric diseases
    • 21441974
    • Liu C (2011) Brain eQTL mapping informs genetic studies of psychiatric diseases. Neurosci Bull 27(2):123-133
    • (2011) Neurosci Bull , vol.27 , Issue.2 , pp. 123-133
    • Liu, C.1
  • 117
    • 52349086806 scopus 로고    scopus 로고
    • Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study
    • 10.1371/journal.pone.0003160 18776929
    • Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Yan H, Deloukas P et al (2008) Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. PLoS ONE 3(9):e3160. doi: 10.1371/journal.pone. 0003160
    • (2008) PLoS ONE , vol.3 , Issue.9 , pp. 3160
    • Liu, Y.Z.1    Wilson, S.G.2    Wang, L.3    Liu, X.G.4    Guo, Y.F.5    Li, J.6    Yan, H.7    Deloukas, P.8
  • 118
    • 63449113425 scopus 로고    scopus 로고
    • Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche
    • 10.1371/journal.pgen.1000420 19282985
    • Liu YZ, Guo YF, Wang L, Tan LJ, Liu XG, Pei YF, Yan H, Xiong DH et al (2009) Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche. PLoS Genet 5(3):e1000420. doi: 10.1371/journal.pgen. 1000420
    • (2009) PLoS Genet , vol.5 , Issue.3 , pp. 1000420
    • Liu, Y.Z.1    Guo, Y.F.2    Wang, L.3    Tan, L.J.4    Liu, X.G.5    Pei, Y.F.6    Yan, H.7    Xiong, D.H.8
  • 119
    • 44849087833 scopus 로고    scopus 로고
    • Mapping genetically compensatory pathways from synthetic lethal interactions in Yeast
    • 10.1371/journal.pone.0001922 18398455
    • Ma X, Tarone AM, Li W (2008) Mapping genetically compensatory pathways from synthetic lethal interactions in Yeast. PLoS ONE 3(4):e1922. doi: 10.1371/journal.pone.0001922
    • (2008) PLoS ONE , vol.3 , Issue.4 , pp. 1922
    • Ma, X.1    Tarone, A.M.2    Li, W.3
  • 120
    • 67651108806 scopus 로고    scopus 로고
    • The genetics of quantitative traits: Challenges and prospects
    • 10.1038/nrg2612 19584810 1:CAS:528:DC%2BD1MXos1WjsL0%3D
    • Mackay TFC, Stone EA, Ayroles JF (2009) The genetics of quantitative traits: challenges and prospects. Nat Rev Genet 10:565-577. doi: 10.1038/nrg2612
    • (2009) Nat Rev Genet , vol.10 , pp. 565-577
    • MacKay, T.F.C.1    Stone, E.A.2    Ayroles, J.F.3
  • 121
    • 80052740749 scopus 로고    scopus 로고
    • Next generation GWAS: Time to focus on phenotype?
    • 10.1161/CIRCGENETICS.111.960765 21846867
    • MacRae CA, Vasan RS (2011) Next generation GWAS: time to focus on phenotype? Circ Cardiovasc Genet 4(4):334-336. doi: 10.1161/CIRCGENETICS.111. 960765
    • (2011) Circ Cardiovasc Genet , vol.4 , Issue.4 , pp. 334-336
    • MacRae, C.A.1    Vasan, R.S.2
  • 122
    • 50549092364 scopus 로고    scopus 로고
    • Genome holography: Deciphering function-form motifs from gene expression data
    • 10.1371/journal.pone.0002708 18628959
    • Madi A, Friedman Y, Roth D, Regev T, Bransburg-Zabary S, Jacob EB (2008) Genome holography: deciphering function-form motifs from gene expression data. PLoS ONE 3(7):e2708. doi: 10.1371/journal.pone.0002708
    • (2008) PLoS ONE , vol.3 , Issue.7 , pp. 2708
    • Madi, A.1    Friedman, Y.2    Roth, D.3    Regev, T.4    Bransburg-Zabary, S.5    Jacob, E.B.6
  • 123
    • 79955987820 scopus 로고    scopus 로고
    • Transgenic plants for phytoremediation
    • (S1) doi: 10.1080/15226514.2011.568549
    • Maestri E, Marmiroli N (2011) Transgenic plants for phytoremediation. Int J Phytoremed 13(S1):264-279. doi: 10.1080/15226514.2011.568549
    • (2011) Int J Phytoremed , vol.13 , pp. 264-279
    • Maestri, E.1    Marmiroli, N.2
  • 124
    • 55549147191 scopus 로고    scopus 로고
    • Personal genomes: The case of the missing heritability
    • 10.1038/456018a 18987709 1:CAS:528:DC%2BD1cXhtlCjtrnM
    • Maher B (2008) Personal genomes: the case of the missing heritability. Nature 456:18-21. doi: 10.1038/456018a
    • (2008) Nature , vol.456 , pp. 18-21
    • Maher, B.1
  • 125
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • 10.1172/JCI34772 18451988 1:CAS:528:DC%2BD1cXlsF2nt7w%3D
    • Manolio TA, Brooks LD, Collins FS (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118(5):1590-1605. doi: 10.1172/JCI34772
    • (2008) J Clin Invest , vol.118 , Issue.5 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 127
    • 77951702343 scopus 로고    scopus 로고
    • Genetic heterogeneity in human disease
    • 10.1016/j.cell.2010.03.032 20403315 1:CAS:528:DC%2BC3cXmtVWns7g%3D
    • McClellan J, King MC (2010) Genetic heterogeneity in human disease. Cell 141:210-217. doi: 10.1016/j.cell.2010.03.032
    • (2010) Cell , vol.141 , pp. 210-217
    • McClellan, J.1    King, M.C.2
  • 128
    • 40549142352 scopus 로고    scopus 로고
    • Analysis of genetic interactions on a genome-wide scale in budding yeast: Diploid-based synthetic lethality analysis by microarray
    • 10.1007/978-1-59745-321-9-15 18392971 1:CAS:528:DC%2BD1cXivFansr8%3D
    • Meluh PB, Pan X, Yuan DS, Tiffany C, Chen O, Sookhai-Mahadeo S, Wang X, Peyser BD et al (2008) Analysis of genetic interactions on a genome-wide scale in budding yeast: diploid-based synthetic lethality analysis by microarray. Methods Mol Biol 416:221-247. doi: 10.1007/978-1-59745-321-9-15
    • (2008) Methods Mol Biol , vol.416 , pp. 221-247
    • Meluh, P.B.1    Pan, X.2    Yuan, D.S.3    Tiffany, C.4    Chen, O.5    Sookhai-Mahadeo, S.6    Wang, X.7    Peyser, B.D.8
  • 129
    • 77957342854 scopus 로고    scopus 로고
    • Data-driven assessment of eQTL mapping methods
    • 10.1186/1471-2164-11-502 20849587
    • Michaelson JJ, Alberts R, Schughart K, Beyer A (2010) Data-driven assessment of eQTL mapping methods. BMC Genomics 11:502. doi: 10.1186/1471-2164-11-502
    • (2010) BMC Genomics , vol.11 , pp. 502
    • Michaelson, J.J.1    Alberts, R.2    Schughart, K.3    Beyer, A.4
  • 130
    • 78649330694 scopus 로고    scopus 로고
    • Synthetic lethal interactions for the development of cancer therapeutics: Biological and methodological advancements
    • 20976469 1:CAS:528:DC%2BC3cXhsVWqtLzF
    • Mizuarai S, Kotani H (2010) Synthetic lethal interactions for the development of cancer therapeutics: biological and methodological advancements. Hum Genet 128(6):567-575
    • (2010) Hum Genet , vol.128 , Issue.6 , pp. 567-575
    • Mizuarai, S.1    Kotani, H.2
  • 131
    • 34547216747 scopus 로고    scopus 로고
    • Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
    • 10.1038/nature06014 17611496 1:CAS:528:DC%2BD2sXotFajurY%3D
    • Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A et al (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448:470-473. doi: 10.1038/nature06014
    • (2007) Nature , vol.448 , pp. 470-473
    • Moffatt, M.F.1    Kabesch, M.2    Liang, L.3    Dixon, A.L.4    Strachan, D.5    Heath, S.6    Depner, M.7    Von Berg, A.8
  • 132
    • 80055069795 scopus 로고    scopus 로고
    • Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: Associations with germline VHL polymorphisms and etiologic risk factors
    • 10.1371/journal.pgen.1002312 22022277 1:CAS:528:DC%2BC3MXhsVWqsLfP
    • Moore LE, Nickerson ML, Brennan P, Toro JR, Jaeger E, Rinsky J, Han SS, Zaridze D et al (2011) Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors. PLoS Genet 7(10):e1002312. doi: 10.1371/journal.pgen.1002312
    • (2011) PLoS Genet , vol.7 , Issue.10 , pp. 1002312
    • Moore, L.E.1    Nickerson, M.L.2    Brennan, P.3    Toro, J.R.4    Jaeger, E.5    Rinsky, J.6    Han, S.S.7    Zaridze, D.8
  • 133
    • 56349133939 scopus 로고    scopus 로고
    • Systems genetics can provide new insights into immune regulation and autoimmunity
    • 10.1016/j.jaut.2008.04.011 1:CAS:528:DC%2BD1cXhsVWrs7zK
    • Morahan G, Peeva V, Mehta M, Williams R (2008) Systems genetics can provide new insights into immune regulation and autoimmunity. J Autoimmunity 31:233-236. doi: 10.1016/j.jaut.2008.04.011
    • (2008) J Autoimmunity , vol.31 , pp. 233-236
    • Morahan, G.1    Peeva, V.2    Mehta, M.3    Williams, R.4
  • 134
    • 80053478616 scopus 로고    scopus 로고
    • ProDiGe: Prioritization of Disease Genes with multitask machine learning from positive and unlabeled examples
    • 10.1186/1471-2105-12-389 21977986
    • Mordelet F, Vert JP (2011) ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples. BMC Bioinformatics 12:389. doi: 10.1186/1471-2105-12-389
    • (2011) BMC Bioinformatics , vol.12 , pp. 389
    • Mordelet, F.1    Vert, J.P.2
  • 135
    • 84863987708 scopus 로고    scopus 로고
    • Computational tools for prioritizing candidate genes: Boosting disease gene discovery
    • 10.1038/nrg3253 22751426 1:CAS:528:DC%2BC38XpsVOmurw%3D
    • Moreau Y, Tranchevent LC (2012) Computational tools for prioritizing candidate genes: boosting disease gene discovery. Nat Rev Genet 13:523-536. doi: 10.1038/nrg3253
    • (2012) Nat Rev Genet , vol.13 , pp. 523-536
    • Moreau, Y.1    Tranchevent, L.C.2
  • 136
    • 4043128071 scopus 로고    scopus 로고
    • Genetic analysis of genome-wide variation in human gene expression
    • 10.1038/nature02797 15269782 1:CAS:528:DC%2BD2cXmsVGls7k%3D
    • Morley M, Molony CM, Weber TM, Devlin JL, Ewens KG, Spielman RS, Cheung VG (2004) Genetic analysis of genome-wide variation in human gene expression. Nature 430:743-747. doi: 10.1038/nature02797
    • (2004) Nature , vol.430 , pp. 743-747
    • Morley, M.1    Molony, C.M.2    Weber, T.M.3    Devlin, J.L.4    Ewens, K.G.5    Spielman, R.S.6    Cheung, V.G.7
  • 137
    • 80053237445 scopus 로고    scopus 로고
    • A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis
    • 10.1371/journal.pone.0025389 21980439 1:CAS:528:DC%2BC3MXhtlCjsL7P
    • Nakaoka H, Cui T, Tajima A, Oka A, Mitsunaga S, Kashiwase K, Homma Y, Sato S et al (2011) A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis. PLoS ONE 6(9):e25389. doi: 10.1371/journal.pone.0025389
    • (2011) PLoS ONE , vol.6 , Issue.9 , pp. 25389
    • Nakaoka, H.1    Cui, T.2    Tajima, A.3    Oka, A.4    Mitsunaga, S.5    Kashiwase, K.6    Homma, Y.7    Sato, S.8
  • 138
    • 79959922954 scopus 로고    scopus 로고
    • PINTA: A web server for network-based gene prioritization from expression data
    • doi: 10.1093/nar/gkr289
    • Nitsch D, Tranchevent LC, Gonçalves JP, Vogt JK, Madeira SC, Moreau Y (2011) PINTA: a web server for network-based gene prioritization from expression data. Nucleic Acids Res 39(W):W334-W338. doi: 10.1093/nar/gkr289
    • (2011) Nucleic Acids Res , vol.39
    • Nitsch D, T.1
  • 139
    • 84865785877 scopus 로고    scopus 로고
    • Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation
    • 10.1038/ncb2556 22864477 1:CAS:528:DC%2BC38XhtFCrt7fP
    • Nittner D, Lambertz I, Clermont F, Mestdagh P, Köhler C, Nielsen SJ, Jochemsen A, Speleman F et al (2012) Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation. Nat Cell Biol 14:958-965. doi: 10.1038/ncb2556
    • (2012) Nat Cell Biol , vol.14 , pp. 958-965
    • Nittner, D.1    Lambertz, I.2    Clermont, F.3    Mestdagh, P.4    Köhler, C.5    Nielsen, S.J.6    Jochemsen, A.7    Speleman, F.8
  • 140
    • 57649121742 scopus 로고    scopus 로고
    • Next-generation genetics in plants
    • 10.1038/nature07629 19079047 1:CAS:528:DC%2BD1cXhsVymtrfM
    • Nordborg M, Weigel D (2008) Next-generation genetics in plants. Nature 456:720-723. doi: 10.1038/nature07629
    • (2008) Nature , vol.456 , pp. 720-723
    • Nordborg, M.1    Weigel, D.2
  • 141
    • 84866411651 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction as a filter-based approach for genome wide association studies
    • 10.3389/fgene.2011.00080 22303374
    • Oki NO, Motsinger-Reif AA (2011) Multifactor dimensionality reduction as a filter-based approach for genome wide association studies. Front Genet 2:80. doi: 10.3389/fgene.2011.00080
    • (2011) Front Genet , vol.2 , pp. 80
    • Oki, N.O.1    Motsinger-Reif, A.A.2
  • 142
    • 59649111554 scopus 로고    scopus 로고
    • Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: Case study of primary immunodeficiencies
    • 10.1093/nar/gkn982 19073697 1:CAS:528:DC%2BD1MXhtlGksLc%3D
    • Ortutay C, Vihinen M (2009) Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies. Nucleic Acids Res 37(2):622-628. doi: 10.1093/nar/gkn982
    • (2009) Nucleic Acids Res , vol.37 , Issue.2 , pp. 622-628
    • Ortutay, C.1    Vihinen, M.2
  • 143
    • 33845657458 scopus 로고    scopus 로고
    • DSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae
    • 10.1016/j.ymeth.2006.07.033 17189863 1:CAS:528:DC%2BD2sXhsFeksA%3D%3D
    • Pan X, Yuan DS, Ooi SL, Wang X, Sookhai-Mahadeo S, Meluh P, Boeke JD (2007) dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae. Methods 41(2):206-221. doi: 10.1016/j.ymeth.2006.07.033
    • (2007) Methods , vol.41 , Issue.2 , pp. 206-221
    • Pan, X.1    Yuan, D.S.2    Ooi, S.L.3    Wang, X.4    Sookhai-Mahadeo, S.5    Meluh, P.6    Boeke, J.D.7
  • 144
    • 78049415626 scopus 로고    scopus 로고
    • An integrative multi-network and multi-classifier approach to predict genetic interactions
    • 10.1371/journal.pcbi.1000928 20838583
    • Pandey G, Zhang B, Chang AN, Myers CL, Zhu J, Kumar V, Schadt EE (2010) An integrative multi-network and multi-classifier approach to predict genetic interactions. PLoS Comput Biol 6(9):e1000928. doi: 10.1371/journal.pcbi.1000928
    • (2010) PLoS Comput Biol , vol.6 , Issue.9 , pp. 1000928
    • Pandey, G.1    Zhang, B.2    Chang, A.N.3    Myers, C.L.4    Zhu, J.5    Kumar, V.6    Schadt, E.E.7
  • 145
    • 79958817255 scopus 로고    scopus 로고
    • Loss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motility
    • 10.1111/j.1750-3639.2010.00464.x 21091576 1:CAS:528:DC%2BC3MXpsFWitrg%3D
    • Petermann A, Haase D, Wetzel A, Balavenkatraman KK, Tenev T, Gührs KH, Friedrich S, Nakamura M et al (2011) Loss of the protein-tyrosine phosphatase DEP-1/PTPRJ drives meningioma cell motility. Brain Pathol 21(4):405-418. doi: 10.1111/j.1750-3639.2010.00464.x
    • (2011) Brain Pathol , vol.21 , Issue.4 , pp. 405-418
    • Petermann, A.1    Haase, D.2    Wetzel, A.3    Balavenkatraman, K.K.4    Tenev, T.5    Gührs, K.H.6    Friedrich, S.7    Nakamura, M.8
  • 146
    • 33750481513 scopus 로고    scopus 로고
    • Heritability and tissue specificity of expression quantitative trait loci
    • 10.1371/journal.pgen.0020172 17054398
    • Petretto E, Mangion J, Dickens NJ, Cook SA, Kumaran MK, Lu H, Fischer J, Maatz H et al (2006) Heritability and tissue specificity of expression quantitative trait loci. PLoS Genet 2:e172. doi: 10.1371/journal.pgen.0020172
    • (2006) PLoS Genet , vol.2 , pp. 172
    • Petretto, E.1    Mangion, J.2    Dickens, N.J.3    Cook, S.A.4    Kumaran, M.K.5    Lu, H.6    Fischer, J.7    Maatz, H.8
  • 147
    • 45949085378 scopus 로고    scopus 로고
    • Polygenes, risk prediction, and targeted prevention of breast cancer
    • 10.1056/NEJMsa0708739 18579814 1:CAS:528:DC%2BD1cXnvFamt7Y%3D
    • Pharoah PD, Antoniou AC, Easton DF, Ponder BA (2008) Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 358(26):2796-2803. doi: 10.1056/NEJMsa0708739
    • (2008) N Engl J Med , vol.358 , Issue.26 , pp. 2796-2803
    • Pharoah, P.D.1    Antoniou, A.C.2    Easton, D.F.3    Ponder, B.A.4
  • 148
    • 54149088214 scopus 로고    scopus 로고
    • Epistasis: The essential role of gene interactions in the structure and evolution of genetic systems
    • 10.1038/nrg2452 18852697 1:CAS:528:DC%2BD1cXht1Ggu77J
    • Phillips PC (2008) Epistasis: the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 9:855-867. doi: 10.1038/nrg2452
    • (2008) Nat Rev Genet , vol.9 , pp. 855-867
    • Phillips, P.C.1
  • 149
    • 38349097316 scopus 로고    scopus 로고
    • Copy-number variation in control population cohorts
    • 10.1093/hmg/ddm321
    • Pinto D, Marshall C, Feuk L, Scherer SW (2007) Copy-number variation in control population cohorts. Hum Mol Genet 17(3):466-467. doi: 10.1093/hmg/ddm321
    • (2007) Hum Mol Genet , vol.17 , Issue.3 , pp. 466-467
    • Pinto, D.1    Marshall, C.2    Feuk, L.3    Scherer, S.W.4
  • 151
    • 37249073867 scopus 로고    scopus 로고
    • Gene expression quantitative trait locus analysis of 16 000 barley genes reveals a complex pattern of genome-wide transcriptional regulation
    • 10.1111/j.1365-313X.2007.03315.x 17944808 1:CAS:528: DC%2BD1cXns1Gmug%3D%3D
    • Potokina E, Druka A, Luo Z, Wise R, Waugh R, Kearsey M (2008) Gene expression quantitative trait locus analysis of 16 000 barley genes reveals a complex pattern of genome-wide transcriptional regulation. Plant J 53:90-101. doi: 10.1111/j.1365-313X.2007.03315.x
    • (2008) Plant J , vol.53 , pp. 90-101
    • Potokina, E.1    Druka, A.2    Luo, Z.3    Wise, R.4    Waugh, R.5    Kearsey, M.6
  • 152
    • 67049143968 scopus 로고    scopus 로고
    • Algorithmic systems biology an opportunity for computer science
    • 10.1145/1506409.1506427
    • Priami C (2009) Algorithmic systems biology an opportunity for computer science. Communication of the ACM 52(5):80-88. doi: 10.1145/1506409.1506427
    • (2009) Communication of the ACM , vol.52 , Issue.5 , pp. 80-88
    • Priami, C.1
  • 153
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P, International Schizophrenia Consortium 10.1038/nature08185
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P, International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460:748-752. doi: 10.1038/nature08185
    • (2009) Nature , vol.460 , pp. 748-752
  • 154
    • 77951860138 scopus 로고    scopus 로고
    • Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome
    • 10.1101/gr.102970.109 20308636 1:CAS:528:DC%2BC3cXlslyis7g%3D
    • Quinlan AR, Clark RA, Sokolova S, Leibowitz ML, Zhang Y, Hurles ME, Mell JC, Hall IM (2010) Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome. Genome Res 20:623-635. doi: 10.1101/gr.102970.109
    • (2010) Genome Res , vol.20 , pp. 623-635
    • Quinlan, A.R.1    Clark, R.A.2    Sokolova, S.3    Leibowitz, M.L.4    Zhang, Y.5    Hurles, M.E.6    Mell, J.C.7    Hall, I.M.8
  • 156
    • 74049101159 scopus 로고    scopus 로고
    • Personal genomics: Information can be harmful
    • 10.1111/j.1365-2362.2009.02232.x 20055897 1:STN:280: DC%2BC3c%2Fht1ertA%3D%3D
    • Ransohoff DF, Khoury MJ (2010) Personal genomics: information can be harmful. Eur J Clin Invest 40(1):64-68. doi: 10.1111/j.1365-2362.2009.02232.x
    • (2010) Eur J Clin Invest , vol.40 , Issue.1 , pp. 64-68
    • Ransohoff, D.F.1    Khoury, M.J.2
  • 157
    • 58849133870 scopus 로고    scopus 로고
    • Mutation analysis of candidate genes SCN1B, KCND3 and ANK2 in patients with clinical diagnosis of long QT syndrome
    • 18052691 1:CAS:528:DC%2BD1MXivFWjtbo%3D
    • Raudenska M, Bittnerova A, Novotny T, Florianova A, Chroust K, Gaillyova R, Semrad B, Kadlecova J et al (2008) Mutation analysis of candidate genes SCN1B, KCND3 and ANK2 in patients with clinical diagnosis of long QT syndrome. Physiol Res 57:857-862
    • (2008) Physiol Res , vol.57 , pp. 857-862
    • Raudenska, M.1    Bittnerova, A.2    Novotny, T.3    Florianova, A.4    Chroust, K.5    Gaillyova, R.6    Semrad, B.7    Kadlecova, J.8
  • 158
    • 78650136869 scopus 로고    scopus 로고
    • Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies
    • 10.1111/j.1469-1809.2010.00630.x 21158748
    • Ritchie MD (2011) Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies. Ann Hum Genet 75(1):172-182. doi: 10.1111/j.1469-1809.2010.00630.x
    • (2011) Ann Hum Genet , vol.75 , Issue.1 , pp. 172-182
    • Ritchie, M.D.1
  • 159
    • 56049121918 scopus 로고    scopus 로고
    • Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases
    • doi: 10.1002/pros.20841
    • Robbins CM, Hernandez W, Ahaghotu C, Bennett J, Hoke G, Mason T, Pettaway CA, et al. (2008) Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases. The Prostate 1-8. doi: 10.1002/pros.20841
    • (2008) The Prostate , pp. 1-8
    • Robbins, C.M.1    Hernandez, W.2    Ahaghotu, C.3    Bennett, J.4    Hoke, G.5    Mason, T.6    Pettaway, C.A.7
  • 160
    • 33750204290 scopus 로고    scopus 로고
    • Genetics of global gene expression
    • 10.1038/nrg1964 17047685 1:CAS:528:DC%2BD28XhtVyktLnP
    • Rockman MV, Kruglyak L (2006) Genetics of global gene expression. Nat Rev Genet 7:862-872. doi: 10.1038/nrg1964
    • (2006) Nat Rev Genet , vol.7 , pp. 862-872
    • Rockman, M.V.1    Kruglyak, L.2
  • 161
    • 33747814487 scopus 로고    scopus 로고
    • TOM: A web-based integrated approach for identification of candidate disease genes
    • 10.1093/nar/gkl340 16845011 1:CAS:528:DC%2BD28Xps1yhtbo%3D
    • Rossi S, Masotti D, Nardini C, Bonora E, Romeo G, Macii E, Benini L, Volinia S (2006) TOM: a web-based integrated approach for identification of candidate disease genes. Nucleic Acids Res 34:W285-W292. doi: 10.1093/nar/gkl340
    • (2006) Nucleic Acids Res , vol.34
    • Rossi, S.1    Masotti, D.2    Nardini, C.3    Bonora, E.4    Romeo, G.5    MacIi, E.6    Benini, L.7    Volinia, S.8
  • 162
    • 27144530248 scopus 로고    scopus 로고
    • Towards a proteome-scale map of the human protein-protein interaction network
    • 10.1038/nature04209 16189514 1:CAS:528:DC%2BD2MXhtFahtLzP
    • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD et al (2005) Towards a proteome-scale map of the human protein-protein interaction network. Nature 437(7062):1173-1178. doi: 10.1038/nature04209
    • (2005) Nature , vol.437 , Issue.7062 , pp. 1173-1178
    • Rual, J.F.1    Venkatesan, K.2    Hao, T.3    Hirozane-Kishikawa, T.4    Dricot, A.5    Li, N.6    Berriz, G.F.7    Gibbons, F.D.8
  • 163
    • 34249724380 scopus 로고    scopus 로고
    • ABME special issue: Systems biology, bioinformatics, and computational biology
    • 10.1007/s10439-007-9325-7
    • Saidel GM, Liang J (2007) ABME special issue: systems biology, bioinformatics, and computational biology. Ann Biomed Eng 35(6):861-862. doi: 10.1007/s10439-007-9325-7
    • (2007) Ann Biomed Eng , vol.35 , Issue.6 , pp. 861-862
    • Saidel, G.M.1    Liang, J.2
  • 164
    • 84860316355 scopus 로고    scopus 로고
    • A two-platform design for next generation genome-wide association studies
    • 10.1002/gepi.21634
    • Sampson JN, Jacobs K, Wang Z, Yeager M, Chanock S, Chatterjee N (2012) A two-platform design for next generation genome-wide association studies. Genet Epidemiol 36(4):401-409. doi: 10.1002/gepi.21634
    • (2012) Genet Epidemiol , vol.36 , Issue.4 , pp. 401-409
    • Sampson, J.N.1    Jacobs, K.2    Wang, Z.3    Yeager, M.4    Chanock, S.5    Chatterjee, N.6
  • 165
    • 79960943621 scopus 로고    scopus 로고
    • Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
    • 10.1371/journal.pgen.1002198 21829380 1:CAS:528:DC%2BC3MXhtVOrt7jM
    • Sanna S, Li B, Mulas A, Sidore C, Kang HM, Jackson AU, Piras MG, Usala G et al (2011) Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet 7(7):e1002198. doi: 10.1371/journal.pgen.1002198
    • (2011) PLoS Genet , vol.7 , Issue.7 , pp. 1002198
    • Sanna, S.1    Li, B.2    Mulas, A.3    Sidore, C.4    Kang, H.M.5    Jackson, A.U.6    Piras, M.G.7    Usala, G.8
  • 166
    • 45149108420 scopus 로고    scopus 로고
    • Mapping the genetic architecture of gene expression in human liver
    • 10.1371/journal.pbio.0060107 18462017
    • Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B et al (2008) Mapping the genetic architecture of gene expression in human liver. PLoS Biol 6(5):e107. doi: 10.1371/journal.pbio.0060107
    • (2008) PLoS Biol , vol.6 , Issue.5 , pp. 107
    • Schadt, E.E.1    Molony, C.2    Chudin, E.3    Hao, K.4    Yang, X.5    Lum, P.Y.6    Kasarskis, A.7    Zhang, B.8
  • 167
    • 3242808027 scopus 로고    scopus 로고
    • Large-scale copy number polymorphism in the human genome
    • 10.1126/science.1098918 15273396 1:CAS:528:DC%2BD2cXlvVOkur4%3D
    • Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, Månér S, Massa H et al (2004) Large-scale copy number polymorphism in the human genome. Science 305:525-528. doi: 10.1126/science.1098918
    • (2004) Science , vol.305 , pp. 525-528
    • Sebat, J.1    Lakshmi, B.2    Troge, J.3    Alexander, J.4    Young, J.5    Lundin, P.6    Månér, S.7    Massa, H.8
  • 168
    • 84857205700 scopus 로고    scopus 로고
    • Uncovering the hidden geometry behind metabolic networks
    • 10.1039/C2MB05306C 22228307 1:CAS:528:DC%2BC38XitVSmtrk%3D
    • Serrano MÁ, Boguñá M, Sagués F (2012) Uncovering the hidden geometry behind metabolic networks. Mol BioSyst 8(3):843-850. doi: 10.1039/C2MB05306C
    • (2012) Mol BioSyst , vol.8 , Issue.3 , pp. 843-850
    • Serrano, M.1    Boguñá, M.2    Sagués, F.3
  • 169
    • 84863411123 scopus 로고    scopus 로고
    • Silico Identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants
    • doi: 10.1155/2012/914843
    • Sharma A, Chauhan RS (2012) In Silico Identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. Comp Funct Genomics. doi: 10.1155/2012/914843
    • (2012) Comp Funct Genomics
    • Sharma, A.1    Chauhan, R.S.2
  • 171
    • 34548427938 scopus 로고    scopus 로고
    • Moving toward a system genetics view of disease
    • 10.1007/s00335-007-9040-6 17653589
    • Sieberts SK, Schadt EE (2007) Moving toward a system genetics view of disease. Mamm Genome 18:389-401. doi: 10.1007/s00335-007-9040-6
    • (2007) Mamm Genome , vol.18 , pp. 389-401
    • Sieberts, S.K.1    Schadt, E.E.2
  • 172
    • 77949519000 scopus 로고    scopus 로고
    • Copy number variant detection in inbred strains from short read sequence data
    • 10.1093/bioinformatics/btp693 20022973 1:CAS:528:DC%2BC3cXhvF2qu7o%3D
    • Simpson JT, McIntyre RE, Adams DJ, Durbin R (2010) Copy number variant detection in inbred strains from short read sequence data. Bioinformatics 26(4):565-567. doi: 10.1093/bioinformatics/btp693
    • (2010) Bioinformatics , vol.26 , Issue.4 , pp. 565-567
    • Simpson, J.T.1    McIntyre, R.E.2    Adams, D.J.3    Durbin, R.4
  • 173
    • 83055197097 scopus 로고    scopus 로고
    • Imaging protein-protein interactions inside living cells via interaction-dependent fluorophore ligation
    • 10.1021/ja206435e 22098454 1:CAS:528:DC%2BC3MXhsV2ju77I
    • Slavoff SA, Liu DS, Cohen JD, Ting AY (2011) Imaging protein-protein interactions inside living cells via interaction-dependent fluorophore ligation. J Am Chem Soc 133(49):19769-19776. doi: 10.1021/ja206435e
    • (2011) J Am Chem Soc , vol.133 , Issue.49 , pp. 19769-19776
    • Slavoff, S.A.1    Liu, D.S.2    Cohen, J.D.3    Ting, A.Y.4
  • 174
    • 84865015653 scopus 로고    scopus 로고
    • Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies
    • 10.1038/cr.2012.82 22613949 1:CAS:528:DC%2BC38XhtFKisL3L
    • Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B et al (2012) Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies. Cell Res 22(8):1227-1245. doi: 10.1038/cr.2012.82
    • (2012) Cell Res , vol.22 , Issue.8 , pp. 1227-1245
    • Steckel, M.1    Molina-Arcas, M.2    Weigelt, B.3    Marani, M.4    Warne, P.H.5    Kuznetsov, H.6    Kelly, G.7    Saunders, B.8
  • 175
    • 25144498379 scopus 로고    scopus 로고
    • A human protein-protein interaction network: A resource for annotating the proteome
    • 10.1016/j.cell.2005.08.029 16169070 1:CAS:528:DC%2BD2MXhtVOrurbK
    • Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M et al (2005) A human protein-protein interaction network: a resource for annotating the proteome. Cell 122(6):957-968. doi: 10.1016/j.cell.2005.08.029
    • (2005) Cell , vol.122 , Issue.6 , pp. 957-968
    • Stelzl, U.1    Worm, U.2    Lalowski, M.3    Haenig, C.4    Brembeck, F.H.5    Goehler, H.6    Stroedicke, M.7    Zenkner, M.8
  • 177
    • 79951521421 scopus 로고    scopus 로고
    • Progress and promise of genome-wide association studies for human complex trait genetics
    • 10.1534/genetics.110.120907 21115973 1:CAS:528:DC%2BC3MXmsVShurY%3D
    • Stranger BE, Stahl EA, Raj T (2011) Progress and promise of genome-wide association studies for human complex trait genetics. Genetics 187(2):367-383. doi: 10.1534/genetics.110.120907
    • (2011) Genetics , vol.187 , Issue.2 , pp. 367-383
    • Stranger, B.E.1    Stahl, E.A.2    Raj, T.3
  • 178
    • 45149115741 scopus 로고    scopus 로고
    • Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification
    • 10.1534/genetics.107.081216 18245842 1:CAS:528:DC%2BD1cXltFagsrk%3D
    • Stylianou IM, Affourtit JP, Shockley KR, Wilpan RY, Abdi FA, Bhardwaj S, Rollins J, Churchill GA et al (2008) Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Genetics 178:1795-1805. doi: 10.1534/genetics.107.081216
    • (2008) Genetics , vol.178 , pp. 1795-1805
    • Stylianou, I.M.1    Affourtit, J.P.2    Shockley, K.R.3    Wilpan, R.Y.4    Abdi, F.A.5    Bhardwaj, S.6    Rollins, J.7    Churchill, G.A.8
  • 179
    • 66749111309 scopus 로고    scopus 로고
    • Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia
    • 10.1016/j.ajhg.2009.04.018 19463983 1:CAS:528:DC%2BD1MXhsFWht7%2FI
    • Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y et al (2009) Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia. Am J Hum Genet 84(6):807-813. doi: 10.1016/j.ajhg.2009.04.018
    • (2009) Am J Hum Genet , vol.84 , Issue.6 , pp. 807-813
    • Sun, M.1    Li, N.2    Dong, W.3    Chen, Z.4    Liu, Q.5    Xu, Y.6    He, G.7    Shi, Y.8
  • 180
    • 84857410370 scopus 로고    scopus 로고
    • High-resolution genetic mapping using the mouse diversity outbred population
    • 10.1534/genetics.111.132597 22345611 1:CAS:528:DC%2BC38XnsVSmsbY%3D
    • Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L et al (2012) High-resolution genetic mapping using the mouse diversity outbred population. Genetics 190(2):437-447. doi: 10.1534/genetics. 111.132597
    • (2012) Genetics , vol.190 , Issue.2 , pp. 437-447
    • Svenson, K.L.1    Gatti, D.M.2    Valdar, W.3    Welsh, C.E.4    Cheng, R.5    Chesler, E.J.6    Palmer, A.A.7    McMillan, L.8
  • 181
    • 77953191436 scopus 로고    scopus 로고
    • XGAP: A uniform and extensible data model and software platform for genotype and phenotype experiments
    • 10.1186/gb-2010-11-3-r27 20214801
    • Swertz MA, Velde KJ, Tesson BM, Scheltema RA, Arends D, Vera G, Alberts R, Dijkstra M et al (2010) XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments. Genome Biol 11:R27. doi: 10.1186/gb-2010-11-3-r27
    • (2010) Genome Biol , vol.11 , pp. 27
    • Swertz, M.A.1    Velde, K.J.2    Tesson, B.M.3    Scheltema, R.A.4    Arends, D.5    Vera, G.6    Alberts, R.7    Dijkstra, M.8
  • 182
    • 79959687662 scopus 로고    scopus 로고
    • An integrated approach to characterize genetic interaction networks in yeast metabolism
    • 10.1038/ng.846 21623372 1:CAS:528:DC%2BC3MXmslSrtb8%3D
    • Szappanos B, Kovács K, Szamecz B, Honti F, Costanzo M, Baryshnikova A, Gelius-Dietrich G, Lercher MJ et al (2011) An integrated approach to characterize genetic interaction networks in yeast metabolism. Nat Genet 43(7):656-662. doi: 10.1038/ng.846
    • (2011) Nat Genet , vol.43 , Issue.7 , pp. 656-662
    • Szappanos, B.1    Kovács, K.2    Szamecz, B.3    Honti, F.4    Costanzo, M.5    Baryshnikova, A.6    Gelius-Dietrich, G.7    Lercher, M.J.8
  • 183
    • 33745154860 scopus 로고    scopus 로고
    • Computational disease gene identification: A concert of methods prioritizes type 2 diabetes and obesity candidate genes
    • 10.1093/nar/gkl381 16757574 1:CAS:528:DC%2BD28XnsFKrtbs%3D
    • Tiffin N, Adie E, Turner F, Brunner HG, van Driel MA, Oti M, Lopez-Bigas N, Ouzounis C et al (2006) Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes. Nucleic Acids Res 34(10):3067-3081. doi: 10.1093/nar/gkl381
    • (2006) Nucleic Acids Res , vol.34 , Issue.10 , pp. 3067-3081
    • Tiffin, N.1    Adie, E.2    Turner, F.3    Brunner, H.G.4    Van Driel, M.A.5    Oti, M.6    Lopez-Bigas, N.7    Ouzounis, C.8
  • 186
    • 84873736810 scopus 로고    scopus 로고
    • Chemical and synthetic genetic array analysis identifies genes that suppress xylose utilization and fermentation in Saccharomyces cerevisiae
    • 10.1534/g3.111.000695 22384336 1:CAS:528:DC%2BC38Xlt12jtrc%3D
    • Usher J, Balderas-Hernandez V, Quon P, Gold ND, Martin VJJ, Mahadevan R, Baetz K (2011) Chemical and synthetic genetic array analysis identifies genes that suppress xylose utilization and fermentation in Saccharomyces cerevisiae. Genes Genomes Genetics 1(4):247-258. doi: 10.1534/g3.111.000695
    • (2011) Genes Genomes Genetics , vol.1 , Issue.4 , pp. 247-258
    • Usher, J.1    Balderas-Hernandez, V.2    Quon, P.3    Gold, N.D.4    Martin, V.J.J.5    Mahadevan, R.6    Baetz, K.7
  • 187
    • 33746326504 scopus 로고    scopus 로고
    • Bioinformatics methods for identifying candidate disease genes
    • 16848981
    • van Driel MA, Brunner HG (2006) Bioinformatics methods for identifying candidate disease genes. Human Genomics 2(6):429-432
    • (2006) Human Genomics , vol.2 , Issue.6 , pp. 429-432
    • Van Driel, M.A.1    Brunner, H.G.2
  • 188
    • 77951974619 scopus 로고    scopus 로고
    • Interpretation of association signals and identification of causal variants from genome-wide association studies
    • 10.1016/j.ajhg.2010.04.003 20434130 1:CAS:528:DC%2BC3cXms1arsb4%3D
    • Wang K, Dickson SP, Stolle CA, Krantz ID, Goldstein DB, Hakonarson H (2010) Interpretation of association signals and identification of causal variants from genome-wide association studies. Am J Hum Genet 86:730-742. doi: 10.1016/j.ajhg.2010.04.003
    • (2010) Am J Hum Genet , vol.86 , pp. 730-742
    • Wang, K.1    Dickson, S.P.2    Stolle, C.A.3    Krantz, I.D.4    Goldstein, D.B.5    Hakonarson, H.6
  • 189
    • 79952698915 scopus 로고    scopus 로고
    • Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation
    • genomebiology.com/2011/12/3/R23 21414197
    • Weber CC, Hurst LD (2011) Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation. Genome Biol 12:R23. doi: genomebiology.com/2011/12/3/R23
    • (2011) Genome Biol , vol.12 , pp. 23
    • Weber, C.C.1    Hurst, L.D.2
  • 190
    • 79960469668 scopus 로고    scopus 로고
    • Synthetic lethality-based targets for discovery of new cancer therapeutics
    • 1:CAS:528:DC%2BC3MXptVWgtrk%3D
    • Weidle UH, Maisel D, Eick D (2011) Synthetic lethality-based targets for discovery of new cancer therapeutics. Cancer Genom Proteom 8:159-172
    • (2011) Cancer Genom Proteom , vol.8 , pp. 159-172
    • Weidle, U.H.1    Maisel, D.2    Eick, D.3
  • 191
    • 34848837299 scopus 로고    scopus 로고
    • Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways
    • 10.1371/journal.pgen.0030162 17941713 1:CAS:528:DC%2BD2sXhtFKmt77M
    • Wentzell AM, Rowe HC, Hansen BG, Ticconi C, Halkier BA, Kliebenstein DJ (2007) Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways. PLoS Genet 3(9):1687-1701. doi: 10.1371/journal.pgen. 0030162
    • (2007) PLoS Genet , vol.3 , Issue.9 , pp. 1687-1701
    • Wentzell, A.M.1    Rowe, H.C.2    Hansen, B.G.3    Ticconi, C.4    Halkier, B.A.5    Kliebenstein, D.J.6
  • 192
    • 34249055193 scopus 로고    scopus 로고
    • Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis
    • 10.1534/genetics.106.064972 17179097 1:CAS:528:DC%2BD2sXltFKhsLs%3D
    • West MA, Kim K, Kliebenstein DJ, van Leeuwen H, Michelmore RW, Doerge RW, St Clair DA (2007) Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis. Genetics 175:1441-1450. doi: 10.1534/genetics.106.064972
    • (2007) Genetics , vol.175 , pp. 1441-1450
    • West, M.A.1    Kim, K.2    Kliebenstein, D.J.3    Van Leeuwen, H.4    Michelmore, R.W.5    Doerge, R.W.6    St Clair, D.A.7
  • 193
    • 28444493739 scopus 로고    scopus 로고
    • Combining probability from independent tests: The weighted Z-method is superior to Fisher's approach
    • 10.1111/j.1420-9101.2005.00917.x 16135132 1:STN:280: DC%2BD2Mvmsl2hug%3D%3D
    • Whitlock MC (2005) Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. J Evol Biol 18(5):1368-1373. doi: 10.1111/j.1420-9101.2005.00917.x
    • (2005) J Evol Biol , vol.18 , Issue.5 , pp. 1368-1373
    • Whitlock, M.C.1
  • 194
    • 77952720637 scopus 로고    scopus 로고
    • Genome-wide association studies and beyond
    • 10.1146/annurev.publhealth.012809.103723
    • Witte JS (2010) Genome-wide association studies and beyond. Ann Rev Pub Health 31:9-20. doi: 10.1146/annurev.publhealth.012809.103723
    • (2010) Ann Rev Pub Health , vol.31 , pp. 9-20
    • Witte, J.S.1
  • 195
    • 79851487367 scopus 로고    scopus 로고
    • Synthetic associations created by rare variants do not explain most GWAS results
    • 10.1371/journal.pbio.1000579 21267061 1:CAS:528:DC%2BC3MXht1Oiu7Y%3D
    • Wray NR, Purcell SM, Visscher PM (2011) Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol 9(1):e1000579. doi: 10.1371/journal.pbio.1000579
    • (2011) PLoS Biol , vol.9 , Issue.1 , pp. 1000579
    • Wray, N.R.1    Purcell, S.M.2    Visscher, P.M.3
  • 196
    • 44949147109 scopus 로고    scopus 로고
    • Gene set enrichment in eQTL data identifies novel annotations and pathway regulators
    • 10.1371/journal.pgen.1000070 18464898
    • Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL et al (2008) Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet 4(5):e1000070. doi: 10.1371/journal.pgen.1000070
    • (2008) PLoS Genet , vol.4 , Issue.5 , pp. 1000070
    • Wu, C.1    Delano, D.L.2    Mitro, N.3    Su, S.V.4    Janes, J.5    McClurg, P.6    Batalov, S.7    Welch, G.L.8
  • 197
    • 77951953607 scopus 로고    scopus 로고
    • Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning
    • 10.1093/bioinformatics/btq044 20134029 1:CAS:528:DC%2BC3cXivFGkurk%3D
    • Wu CC, Asgharzadeh S, Triche TJ, D'Argenio DZ (2010) Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning. Bioinformatics 26(6):807-813. doi: 10.1093/bioinformatics/btq044
    • (2010) Bioinformatics , vol.26 , Issue.6 , pp. 807-813
    • Wu, C.C.1    Asgharzadeh, S.2    Triche, T.J.3    D'Argenio, D.Z.4
  • 198
    • 64849083125 scopus 로고    scopus 로고
    • CNV-seq, a new method to detect copy number variation using high-throughput sequencing
    • 10.1186/1471-2105-10-80 19267900
    • Xie C, Tammi M (2009) CNV-seq, a new method to detect copy number variation using high-throughput sequencing. BMC Bioinformatics 10:80. doi: 10.1186/1471-2105-10-80
    • (2009) BMC Bioinformatics , vol.10 , pp. 80
    • Xie, C.1    Tammi, M.2
  • 199
    • 80052681068 scopus 로고    scopus 로고
    • Building phenotype networks to improve QTL detection: A comparative analysis of fatty acid and fat traits in pigs
    • 10.1111/j.1439-0388.2011.00928.x 21906179 1:CAS:528:DC%2BC3MXhtlCgur3M
    • Yang B, Navarro N, Noguera JL, Muñoz M, Guo TF, Yang KX, Ma JW, Folch JM et al (2011a) Building phenotype networks to improve QTL detection: a comparative analysis of fatty acid and fat traits in pigs. J Anim Breed Genet 128:329-343. doi: 10.1111/j.1439-0388.2011.00928.x
    • (2011) J Anim Breed Genet , vol.128 , pp. 329-343
    • Yang, B.1    Navarro, N.2    Noguera, J.L.3    Muñoz, M.4    Guo, T.F.5    Yang, K.X.6    Ma, J.W.7    Folch, J.M.8
  • 200
    • 82255185481 scopus 로고    scopus 로고
    • MiREnvironment Database: Providing a bridge for microRNAs, environmental factors, and phenotypes
    • 10.1093/bioinformatics/btr556 21984757 1:CAS:528:DC%2BC3MXhsFCit7rF
    • Yang Q, Qiu C, Yang J, Wu Q, Cui Q (2011b) miREnvironment Database: providing a bridge for microRNAs, environmental factors, and phenotypes. Bioinformatics 27(23):3329-3330. doi: 10.1093/bioinformatics/btr556
    • (2011) Bioinformatics , vol.27 , Issue.23 , pp. 3329-3330
    • Yang, Q.1    Qiu, C.2    Yang, J.3    Wu, Q.4    Cui, Q.5
  • 201
    • 70350694443 scopus 로고    scopus 로고
    • Pindel: A pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads
    • 10.1093/bioinformatics/btp394 19561018 1:CAS:528:DC%2BD1MXhtlWls7nP
    • Ye K, Schulz MH, Long Q, Apweiler R, Ning Z (2009) Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads. Bioinformatics 25:2865-2871. doi: 10.1093/bioinformatics/btp394
    • (2009) Bioinformatics , vol.25 , pp. 2865-2871
    • Ye, K.1    Schulz, M.H.2    Long, Q.3    Apweiler, R.4    Ning, Z.5
  • 202
    • 77951623857 scopus 로고    scopus 로고
    • A new multiple regression approach for the construction of genetic regulatory networks
    • 10.1016/j.artmed.2009.11.001
    • Zhang SQ, Ching WK, Tsing NK, Leug HY, Guo D (2010) A new multiple regression approach for the construction of genetic regulatory networks. Artificial Intel in Med 48(2):153-160. doi: 10.1016/j.artmed.2009.11.001
    • (2010) Artificial Intel in Med , vol.48 , Issue.2 , pp. 153-160
    • Zhang, S.Q.1    Ching, W.K.2    Tsing, N.K.3    Leug, H.Y.4    Guo, D.5
  • 203
    • 44449158290 scopus 로고    scopus 로고
    • Transcription network construction for large-scale microarray datasets using a high-performance computing approach
    • 10.1186/1471-2164-9-S1-S5
    • Zhu M, Wu Q (2008) Transcription network construction for large-scale microarray datasets using a high-performance computing approach. BMC Genomics 9(Suppl 1):S5. doi: 10.1186/1471-2164-9-S1-S5
    • (2008) BMC Genomics , vol.9 , Issue.SUPPL. 1 , pp. 5
    • Zhu, M.1    Wu, Q.2
  • 204
    • 36249020808 scopus 로고    scopus 로고
    • Candidate gene identification approach: Progress and challenges
    • 10.7150/ijbs.3.420
    • Zhu M, Zhao S (2008) Candidate gene identification approach: progress and challenges. Int J Biol Sci 3(7):420-427. doi: 10.7150/ijbs.3.420
    • (2008) Int J Biol Sci , vol.3 , Issue.7 , pp. 420-427
    • Zhu, M.1    Zhao, S.2
  • 205
    • 62749129877 scopus 로고    scopus 로고
    • Understanding quantitative genetics in the systems biology era
    • 10.7150/ijbs.5.161 19173038 1:CAS:528:DC%2BD1MXnsl2rurw%3D
    • Zhu M, Yu M, Zhao S (2009) Understanding quantitative genetics in the systems biology era. Int J Biol Sci 5(2):161-170. doi: 10.7150/ijbs.5.161
    • (2009) Int J Biol Sci , vol.5 , Issue.2 , pp. 161-170
    • Zhu, M.1    Yu, M.2    Zhao, S.3
  • 206
    • 80053379964 scopus 로고    scopus 로고
    • Overexpression of a cotton cyclophilin gene (GhCyp1) in transgenic tobacco plants confers dual tolerance to salt stress and Pseudomonas syringae pv. tabaci infection
    • 10.1016/j.plaphy.2011.09.001 22000049 1:CAS:528:DC%2BC3MXhtlejtbbP
    • Zhu C, Wang Y, Li Y, Bhatti KH, Tian Y, Wu J (2011) Overexpression of a cotton cyclophilin gene (GhCyp1) in transgenic tobacco plants confers dual tolerance to salt stress and Pseudomonas syringae pv. tabaci infection. Plant Physiol Biochem 49(11):1264-1271. doi: 10.1016/j.plaphy.2011.09.001
    • (2011) Plant Physiol Biochem , vol.49 , Issue.11 , pp. 1264-1271
    • Zhu, C.1    Wang, Y.2    Li, Y.3    Bhatti, K.H.4    Tian, Y.5    Wu, J.6
  • 207
    • 84863155651 scopus 로고    scopus 로고
    • Treatment- and population-dependent activity patterns of behavioral and expression QTLs
    • 10.1371/journal.pone.0031805 22359631 1:CAS:528:DC%2BC38XjtFWjtbk%3D
    • Ziebarth JD, Cook MN, Wang X, Williams RW, Lu L, Cui Y (2012) Treatment- and population-dependent activity patterns of behavioral and expression QTLs. PLoS ONE 7(2):e31805. doi: 10.1371/journal.pone.0031805
    • (2012) PLoS ONE , vol.7 , Issue.2 , pp. 31805
    • Ziebarth, J.D.1    Cook, M.N.2    Wang, X.3    Williams, R.W.4    Lu, L.5    Cui, Y.6
  • 208
    • 77958510038 scopus 로고    scopus 로고
    • CopyMap: Localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals
    • 10.1093/bioinformatics/btq515 20926418
    • Zöllner S (2010) CopyMap: localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals. Bioinformatics 26(21):2776-2777. doi: 10.1093/bioinformatics/btq515
    • (2010) Bioinformatics , vol.26 , Issue.21 , pp. 2776-2777
    • Zöllner, S.1
  • 209
    • 33846873672 scopus 로고    scopus 로고
    • EQTL Viewer: Visualizing how sequence variation affects genome-wide transcription
    • 10.1186/1471-2105-8-7 17212828
    • Zou W, Aylor DL, Zeng ZB (2007) eQTL Viewer: visualizing how sequence variation affects genome-wide transcription. BMC Bioinformatics 8:7. doi: 10.1186/1471-2105-8-7
    • (2007) BMC Bioinformatics , vol.8 , pp. 7
    • Zou, W.1    Aylor, D.L.2    Zeng, Z.B.3
  • 210
    • 84856405512 scopus 로고    scopus 로고
    • The mystery of missing heritability: Genetic interactions create phantom heritability
    • 10.1073/pnas.1119675109 22223662 1:CAS:528:DC%2BC38XislWks7o%3D
    • Zuk O, Hechter E, Sunyaev SR, Lander ES (2012) The mystery of missing heritability: genetic interactions create phantom heritability. Proc Natl Acad Sci USA 109(4):1193-1198. doi: 10.1073/pnas.1119675109
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.4 , pp. 1193-1198
    • Zuk, O.1    Hechter, E.2    Sunyaev, S.R.3    Lander, E.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.