A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Nakaoka, Hirofumi ^a   Cui, Tailin ^b   Tajima, Atsushi ^b,c   Oka, Akira ^b   Mitsunaga, Shigeki ^b   Kashiwase, Koichi ^d   Homma, Yasuhiko ^e   Sato, Shinji ^e   Suzuki, Yasuo ^e   Inoko, Hidetoshi ^b   Inoue, Ituro ^a,b  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d Tokyo Red Cross Blood Center   (Japan)

^e TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN;

ARTICLE; CONTROLLED STUDY; ETHNICITY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; RECEIVER OPERATING CHARACTERISTIC; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW; ANIMAL; BIOLOGICAL MODEL; GENE REGULATORY NETWORK; GENETIC PREDISPOSITION; GENETIC PROCEDURES; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; MOUSE; PROTEIN PROTEIN INTERACTION; SYSTEMS BIOLOGY;

MUS;

ANIMALS; ARTHRITIS, RHEUMATOID; GENE REGULATORY NETWORKS; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETIC TECHNIQUES; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICE; MODELS, GENETIC; PROTEIN INTERACTION MAPS; SYSTEMS BIOLOGY;

EID: 80053237445     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025389     Document Type: Article

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