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Volumn 2, Issue NOV, 2011, Pages

Multifactor dimensionality reduction as a filter-based approach for genome wide association studies

Author keywords

Epistasis; GWAS; Multifactor dimensionality reduction

Indexed keywords


EID: 84866411651     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2011.00080     Document Type: Article
Times cited : (10)

References (60)
  • 1
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • Breiman, L. (2001). Random forests. Mach. Learn. 45, 5-32.
    • (2001) Mach. Learn. , vol.45 , pp. 5-32
    • Breiman, L.1
  • 2
    • 78149255580 scopus 로고    scopus 로고
    • RAPID Detection of gene-gene interactions in genome-wide association studies
    • Brinza, D., Schultz, M., Tesler, G., and Bafna, V. (2010). RAPID Detection of gene-gene interactions in genome-wide association studies. Bioinformatics 26, 2856-2862.
    • (2010) Bioinformatics , vol.26 , pp. 2856-2862
    • Brinza, D.1    Schultz, M.2    Tesler, G.3    Bafna, V.4
  • 4
    • 63249107210 scopus 로고    scopus 로고
    • Improving strategies for detecting genetic patterns of disease susceptibility in association studies
    • Calle, M. L., Urrea, V., Vellalta, G., Malats, N., and Steen, K. V. (2008). Improving strategies for detecting genetic patterns of disease susceptibility in association studies. Stat. Med. 27, 6532-6546.
    • (2008) Stat. Med. , vol.27 , pp. 6532-6546
    • Calle, M.L.1    Urrea, V.2    Vellalta, G.3    Malats, N.4    Steen, K.V.5
  • 5
    • 0027534004 scopus 로고
    • The risk of determining risk with multivariable models
    • Concato, J., Feinstein, A. R., and Holford, T. R. (1993). The risk of determining risk with multivariable models. Ann. Intern. Med. 118, 201-210.
    • (1993) Ann. Intern. Med. , vol.118 , pp. 201-210
    • Concato, J.1    Feinstein, A.R.2    Holford, T.R.3
  • 6
    • 33847021135 scopus 로고    scopus 로고
    • The use of the restricted partition method with case-control data
    • Culverhouse, R. (2007). The use of the restricted partition method with case-control data. Hum. Hered. 63, 93-100.
    • (2007) Hum. Hered. , vol.63 , pp. 93-100
    • Culverhouse, R.1
  • 7
    • 4344659001 scopus 로고    scopus 로고
    • Detecting epistatic interactions contributing to quantitative traits
    • Culverhouse, R., Klein, T., and Shannon, W. (2004). Detecting epistatic interactions contributing to quantitative traits. Genet. Epidemiol. 27, 141-152.
    • (2004) Genet. Epidemiol. , vol.27 , pp. 141-152
    • Culverhouse, R.1    Klein, T.2    Shannon, W.3
  • 8
    • 0036155238 scopus 로고    scopus 로고
    • A perspective on epistasis: limits of models displaying no main effect
    • Culverhouse, R., Suarez, B. K., Lin, J., and Reich, T. (2002). A perspective on epistasis: limits of models displaying no main effect. Am. J. Hum. Genet. 70, 461-471.
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 461-471
    • Culverhouse, R.1    Suarez, B.K.2    Lin, J.3    Reich, T.4
  • 9
    • 39049176465 scopus 로고    scopus 로고
    • Data simulation software for whole-genome association and other studies in human genetics
    • Dudek, S. M., Motsinger, A. A., Velez, D. R., Williams, S. M., and Ritchie, M. D. (2006). Data simulation software for whole-genome association and other studies in human genetics. Pac. Symp. Biocomput. 2006, 499-510.
    • (2006) Pac. Symp. Biocomput. , vol.2006 , pp. 499-510
    • Dudek, S.M.1    Motsinger, A.A.2    Velez, D.R.3    Williams, S.M.4    Ritchie, M.D.5
  • 10
    • 57449101697 scopus 로고    scopus 로고
    • Exploring the performance of multifactor dimensionality reduction in large scale SNP studies and in the presence of genetic heterogeneity among epistatic disease models
    • Edwards, T. L., Lewis, K., Velez, D. R., Dudek, S., and Ritchie, M. D. (2009). Exploring the performance of multifactor dimensionality reduction in large scale SNP studies and in the presence of genetic heterogeneity among epistatic disease models. Hum. Hered. 67, 183-192.
    • (2009) Hum. Hered. , vol.67 , pp. 183-192
    • Edwards, T.L.1    Lewis, K.2    Velez, D.R.3    Dudek, S.4    Ritchie, M.D.5
  • 11
    • 77952557918 scopus 로고    scopus 로고
    • Missing heritability and strategies for finding the underlying causes of complex disease
    • Eichler, E. E., Flint, J., Gibson, G., Kong, A., Leal, S. M., Moore, J. H., and Nadeau, J. H. (2010). Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet. 11, 446-450.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 446-450
    • Eichler, E.E.1    Flint, J.2    Gibson, G.3    Kong, A.4    Leal, S.M.5    Moore, J.H.6    Nadeau, J.H.7
  • 12
    • 33749388527 scopus 로고    scopus 로고
    • Two-stage two-locus models in genome-wide association
    • doi: 10.1371/journal.pgen.0020157
    • Evans, D. M., Marchini, J., Morris, A. P., and Cardon, L. R. (2006). Two-stage two-locus models in genome-wide association. PLoS Genet. 2, e157. doi: 10.1371/journal.pgen.0020157
    • (2006) PLoS Genet , vol.2
    • Evans, D.M.1    Marchini, J.2    Morris, A.P.3    Cardon, L.R.4
  • 13
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer, K. A., Murray, S. S., Schork, N. J., and Topol, E. J. (2009). Human genetic variation and its contribution to complex traits. Nat. Rev. Genet. 10, 241-251.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 14
    • 79955564727 scopus 로고    scopus 로고
    • The effects of linkage disequilibrium in large scale SNP datasets for MDR
    • Grady, B., Torstenson, E., and Ritchie, M. (2011). The effects of linkage disequilibrium in large scale SNP datasets for MDR. BioData Min. 4, 11.
    • (2011) BioData Min , vol.4 , pp. 11
    • Grady, B.1    Torstenson, E.2    Ritchie, M.3
  • 15
    • 77949614812 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS
    • Greene, C. S., Sinnott-Armstrong, N. A., Himmelstein, D. S., Park, P. J., Moore, J. H., and Harris, B. T. (2010). Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS. Bioinformatics 26, 694-695.
    • (2010) Bioinformatics , vol.26 , pp. 694-695
    • Greene, C.S.1    Sinnott-Armstrong, N.A.2    Himmelstein, D.S.3    Park, P.J.4    Moore, J.H.5    Harris, B.T.6
  • 16
    • 0037433052 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    • Hahn, L. W., Ritchie, M. D., and Moore, J. H. (2003). Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics 19, 376-382.
    • (2003) Bioinformatics , vol.19 , pp. 376-382
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 18
    • 74049126629 scopus 로고    scopus 로고
    • Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene interaction in a case-control study
    • doi: 10.1186/1471-2350-10-127
    • He, H., Oetting, W., Brott, M., and Basu, S. (2009). Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene interaction in a case-control study. BMC Med. Genet. 10, 127. doi: 10.1186/1471-2350-10-127
    • (2009) BMC Med. Genet. , vol.10 , pp. 127
    • He, H.1    Oetting, W.2    Brott, M.3    Basu, S.4
  • 20
    • 0000996209 scopus 로고
    • Evaporative cooling of magnetically trapped and compressed spin-polarized hydrogen
    • Hess, H. F. (1986). Evaporative cooling of magnetically trapped and compressed spin-polarized hydrogen. Phys. Rev. B 34, 3476
    • (1986) Phys. Rev. B , vol.34 , pp. 3476
    • Hess, H.F.1
  • 21
    • 0042881041 scopus 로고    scopus 로고
    • Mathematical multi-locus approaches to localizing complex human trait genes
    • Hoh, J., and Ott, J. (2003). Mathematical multi-locus approaches to localizing complex human trait genes. Nat. Rev. Genet. 4, 701-709.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 701-709
    • Hoh, J.1    Ott, J.2
  • 22
    • 0035214299 scopus 로고    scopus 로고
    • Trimming, weighting, and grouping SNPs in human case-control association studies
    • Hoh, J., Wille, A., and Ott, J. (2001). Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res. 11, 2115-2119.
    • (2001) Genome Res , vol.11 , pp. 2115-2119
    • Hoh, J.1    Wille, A.2    Ott, J.3
  • 24
    • 77955715381 scopus 로고    scopus 로고
    • SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder
    • Hu, X., Liu, Q., Zhang, Z., Li, Z., Wang, S., He, L., and Shi, Y. (2010). SHEsisEpi, a GPU-enhanced genome-wide SNP-SNP interaction scanning algorithm, efficiently reveals the risk genetic epistasis in bipolar disorder. Cell Res. 20, 854-857.
    • (2010) Cell Res , vol.20 , pp. 854-857
    • Hu, X.1    Liu, Q.2    Zhang, Z.3    Li, Z.4    Wang, S.5    He, L.6    Shi, Y.7
  • 26
    • 84992726552 scopus 로고
    • Estimating attributes: analysis and extensions of RELIEF
    • F. Bergadano, and L. De Raedt (Berlin: Springer)
    • Kononenko, I. (1994). "Estimating attributes: analysis and extensions of RELIEF," in Machine Learning: ECML-94, Vol. 784, ed. F. Bergadano, and L. De Raedt (Berlin: Springer), 171-182.
    • (1994) in Machine Learning: ECML-94 ed , vol.784 , pp. 171-182
    • Kononenko, I.1
  • 27
    • 42249099044 scopus 로고    scopus 로고
    • Increasing the power of identifying gene x gene interactions in genome-wide association studies
    • Kooperberg, C., and Leblanc, M. (2008). Increasing the power of identifying gene x gene interactions in genome-wide association studies. Genet. Epidemiol. 32, 255-263.
    • (2008) Genet. Epidemiol. , vol.32 , pp. 255-263
    • Kooperberg, C.1    Leblanc, M.2
  • 28
    • 77955144299 scopus 로고    scopus 로고
    • Replication in genome-wide association studies
    • Kraft, P., Zeggini, E., and Ioannidis, J. P. (2009). Replication in genome-wide association studies. Stat. Sci. 24, 561-573.
    • (2009) Stat. Sci. , vol.24 , pp. 561-573
    • Kraft, P.1    Zeggini, E.2    Ioannidis, J.P.3
  • 29
    • 70450235051 scopus 로고    scopus 로고
    • A robust test for two-stage design in genome-wide association studies
    • Kwak, M., Joo, J., and Zheng, G. (2009). A robust test for two-stage design in genome-wide association studies. Biometrics 65, 1288-1295.
    • (2009) Biometrics , vol.65 , pp. 1288-1295
    • Kwak, M.1    Joo, J.2    Zheng, G.3
  • 30
    • 0033940280 scopus 로고    scopus 로고
    • A complete enumeration and classification of two-locus disease models
    • Li, W., and Reich, J. (2000). A complete enumeration and classification of two-locus disease models. Hum. Hered. 50, 334-349.
    • (2000) Hum. Hered. , vol.50 , pp. 334-349
    • Li, W.1    Reich, J.2
  • 32
    • 16844366786 scopus 로고    scopus 로고
    • Genome-wide strategies for detecting multiple loci that influence complex diseases
    • Marchini, J., Donnelly, P., and Cardon, L. R. (2005). Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat. Genet. 37, 413-417.
    • (2005) Nat. Genet. , vol.37 , pp. 413-417
    • Marchini, J.1    Donnelly, P.2    Cardon, L.R.3
  • 33
    • 0002801737 scopus 로고
    • Multivariate information transmission
    • McGill, W. (1954). Multivariate information transmission. Psychometrika 19, 97-116.
    • (1954) Psychometrika , vol.19 , pp. 97-116
    • McGill, W.1
  • 34
    • 63449100294 scopus 로고    scopus 로고
    • Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis
    • doi: 10.1371/journal.pgen.1000432
    • McKinney, B. A., Crowe, James E. Jr., Guo, J., and Tian, D. (2009). Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet. 5, e1000432. doi: 10.1371/journal.pgen.1000432
    • (2009) PLoS Genet , vol.5
    • McKinney, B.A.1    Crowe Jr., J.E.2    Guo, J.3    Tian, D.4
  • 35
    • 34548577158 scopus 로고    scopus 로고
    • Evaporative cooling feature selection for genotypic data involving interactions
    • McKinney, B. A., Reif, D. M., White, B. C., Crowe, J. E., and Moore, J. H. (2007). Evaporative cooling feature selection for genotypic data involving interactions. Bioinformatics 23, 2113-2120.
    • (2007) Bioinformatics , vol.23 , pp. 2113-2120
    • McKinney, B.A.1    Reif, D.M.2    White, B.C.3    Crowe, J.E.4    Moore, J.H.5
  • 36
    • 28444496622 scopus 로고    scopus 로고
    • Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data
    • doi: 10.1186/1471-2156-6-S1-S145
    • Mei, H., Ma, D., Ashley-Koch, A., and Martin, E. R. (2005). Extension of multifactor dimensionality reduction for identifying multilocus effects in the GAW14 simulated data. BMC Genet. 6(Suppl. 1), S145. doi: 10.1186/1471-2156-6-S1-S145
    • (2005) BMC Genet , vol.6 , Issue.SUPPL. 1
    • Mei, H.1    Ma, D.2    Ashley-Koch, A.3    Martin, E.R.4
  • 37
    • 0002612450 scopus 로고    scopus 로고
    • Application of genetic algorithms to the discovery of complex models for simulation studies in human genetics GECCO 2002
    • E. Cantu-Paz, K. Mathias, R. Roy, D. Davis, R. Poli, K. Balakrishnan, V. Honavar, G. Rudolph, J. Wegener, L. Bull, M. A. Potter, A. C. Schultz, J. F. Miller, E. Burke, N. Jonoska, and W. B. Langdon (New York, NY: Morgan Kaufmann Publishers)
    • Moore, J. H., Hahn, L. W., Ritchie, M. D., Thornton, T. A., and White, B. C. (2002). "Application of genetic algorithms to the discovery of complex models for simulation studies in human genetics," in GECCO 2002: Proceedings of the Genetic and Evolutionary Computation Conference Application of Genetic Algorithms to the Discovery of Complex Models for Simulation Studies in Human Genetics, eds E. Cantu-Paz, K. Mathias, R. Roy, D. Davis, R. Poli, K. Balakrishnan, V. Honavar, G. Rudolph, J. Wegener, L. Bull, M. A. Potter, A. C. Schultz, J. F. Miller, E. Burke, N. Jonoska, and W. B. Langdon (New York, NY: Morgan Kaufmann Publishers), 1150-1155
    • (2002) Proceedings of the Genetic and Evolutionary Computation Conference Application of Genetic Algorithms to the Discovery of Complex Models for Simulation Studies in Human Genetics, eds , pp. 1150-1155
    • Moore, J.H.1    Hahn, L.W.2    Ritchie, M.D.3    Thornton, T.A.4    White, B.C.5
  • 38
    • 2142705388 scopus 로고    scopus 로고
    • The challenges of whole-genome approaches to common diseases
    • Moore, J. H., and Ritchie, M. D. (2004). The challenges of whole-genome approaches to common diseases. JAMA 291, 1642-1643.
    • (2004) JAMA , vol.291 , pp. 1642-1643
    • Moore, J.H.1    Ritchie, M.D.2
  • 39
    • 0036260234 scopus 로고    scopus 로고
    • New strategies for identifying gene-gene interactions in hypertension
    • Moore, J. H., and Williams, S. M. (2002). New strategies for identifying gene-gene interactions in hypertension. Ann. Med. 34, 88-95.
    • (2002) Ann. Med. , vol.34 , pp. 88-95
    • Moore, J.H.1    Williams, S.M.2
  • 41
    • 33747613579 scopus 로고    scopus 로고
    • The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction
    • Motsinger, A. A., and Ritchie, M. D. (2006). The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction. Genet. Epidemiol. 30, 546-555.
    • (2006) Genet. Epidemiol. , vol.30 , pp. 546-555
    • Motsinger, A.A.1    Ritchie, M.D.2
  • 42
    • 78650962589 scopus 로고    scopus 로고
    • Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
    • doi: 10.1186/1471-2105-12-9
    • Pan, D., Li, Q., Jiang, N., Liu, A., and Yu, K. (2011). Robust joint analysis allowing for model uncertainty in two-stage genetic association studies. BMC Bioinformatics 12, 9. doi: 10.1186/1471-2105-12-9
    • (2011) BMC Bioinformatics , vol.12 , Issue.9
    • Pan, D.1    Li, Q.2    Jiang, N.3    Liu, A.4    Yu, K.5
  • 43
    • 33947586216 scopus 로고    scopus 로고
    • Multilocus analysis of atopy in Korean children using multifactor-dimensionality reduction
    • Park, H., Shin, E., Lee, J., Kwon, H., Chun, E., Kim, S., Chang, Y., Kim, Y., Min, K., Kim, Y., and Cho, S. (2007). Multilocus analysis of atopy in Korean children using multifactor-dimensionality reduction. Thorax 62, 265-269.
    • (2007) Thorax , vol.62 , pp. 265-269
    • Park, H.1    Shin, E.2    Lee, J.3    Kwon, H.4    Chun, E.5    Kim, S.6    Chang, Y.7    Kim, Y.8    Min, K.9    Kim, Y.10    Cho, S.11
  • 44
    • 0030474271 scopus 로고    scopus 로고
    • A simulation study of the number of events per variable in logistic regression analysis
    • Peduzzi, P., Concato, J., Kemper, E., Holford, T. R., and Feinstein, A. R. (1996). A simulation study of the number of events per variable in logistic regression analysis. J. Clin. Epidemiol. 49, 1373-1379.
    • (1996) J. Clin. Epidemiol. , vol.49 , pp. 1373-1379
    • Peduzzi, P.1    Concato, J.2    Kemper, E.3    Holford, T.R.4    Feinstein, A.R.5
  • 47
    • 78650136869 scopus 로고    scopus 로고
    • Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies
    • Ritchie, M. D. (2011). Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies. Ann. Hum. Genet. 75, 172-182.
    • (2011) Ann. Hum. Genet. , vol.75 , pp. 172-182
    • Ritchie, M.D.1
  • 48
    • 0037310257 scopus 로고    scopus 로고
    • Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity
    • Ritchie, M. D., Hahn, L. W., and Moore, J. H. (2003). Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genet. Epidemiol. 24, 150-157.
    • (2003) Genet. Epidemiol. , vol.24 , pp. 150-157
    • Ritchie, M.D.1    Hahn, L.W.2    Moore, J.H.3
  • 49
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    • Ritchie, M. D., Hahn, L. W., Roodi, N., Bailey, L. R., Dupont, W. D., Parl, F. F., and Moore, J. H. (2001). Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am. J. Hum. Genet. 69, 138-147.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Parl, F.F.6    Moore, J.H.7
  • 50
    • 49549111404 scopus 로고    scopus 로고
    • Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence
    • Saccone, S. F., Saccone, N. L., Swan, G. E., Madden, P. A. F., Goate, A. M., Rice, J. P., and Bierut, L. J. (2008). Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. Bioinformatics 24, 1805-1811.
    • (2008) Bioinformatics , vol.24 , pp. 1805-1811
    • Saccone, S.F.1    Saccone, N.L.2    Swan, G.E.3    Madden, P.A.F.4    Goate, A.M.5    Rice, J.P.6    Bierut, L.J.7
  • 51
    • 0042859846 scopus 로고    scopus 로고
    • Optimal two-stage genotyping in population-based association studies
    • Satagopan, J. M., and Elston, R. C. (2003). Optimal two-stage genotyping in population-based association studies. Genet. Epidemiol. 25, 149-157.
    • (2003) Genet. Epidemiol. , vol.25 , pp. 149-157
    • Satagopan, J.M.1    Elston, R.C.2
  • 52
    • 4444317393 scopus 로고    scopus 로고
    • Two-stage designs for gene-disease association studies with sample size constraints
    • Satagopan, J. M., Venkatraman, E. S., and Begg, C. B. (2004). Two-stage designs for gene-disease association studies with sample size constraints. Biometrics 60, 589-597.
    • (2004) Biometrics , vol.60 , pp. 589-597
    • Satagopan, J.M.1    Venkatraman, E.S.2    Begg, C.B.3
  • 53
    • 36248975593 scopus 로고    scopus 로고
    • Optimal designs for two-stage genome-wide association studies
    • Skol, A. D., Scott, L. J., Abecasis, G. R., and Boehnke, M. (2007). Optimal designs for two-stage genome-wide association studies. Genet. Epidemiol. 31, 776-788.
    • (2007) Genet. Epidemiol. , vol.31 , pp. 776-788
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 55
    • 34247338434 scopus 로고    scopus 로고
    • A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction
    • Velez, D. R., White, B. C., Motsinger, A. A., Bush, W. S., Ritchie, M. D., Williams, S. M., and Moore, J. H. (2007). A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction. Genet. Epidemiol. 31, 306-315.
    • (2007) Genet. Epidemiol. , vol.31 , pp. 306-315
    • Velez, D.R.1    White, B.C.2    Motsinger, A.A.3    Bush, W.S.4    Ritchie, M.D.5    Williams, S.M.6    Moore, J.H.7
  • 56
    • 77956395423 scopus 로고    scopus 로고
    • BOOST: a fast approach to detecting gene-gene interactions in genome-wide case-control studies
    • Wan, X., Can, Y., Qiang, Y., Hong, X., Xiaodan, F., Nelson, L. S. T., and Weichuan, Y. (2010). BOOST: a fast approach to detecting gene-gene interactions in genome-wide case-control studies. Am. J. Hum. Genet. 87, 325-340.
    • (2010) Am. J. Hum. Genet. , vol.87 , pp. 325-340
    • Wan, X.1    Can, Y.2    Qiang, Y.3    Hong, X.4    Xiaodan, F.5    Nelson, L.S.T.6    Weichuan, Y.7
  • 57
    • 33646250184 scopus 로고    scopus 로고
    • Optimal two-stage designs for genome-wide association scans
    • Wang, H., Thomas, D. C., Pe'er, I., and Stram, D. O. (2006). Optimal two-stage designs for genome-wide association scans. Genet. Epidemiol. 30, 356-368
    • (2006) Genet. Epidemiol. , vol.30 , pp. 356-368
    • Wang, H.1    Thomas, D.C.2    Pe'er, I.3    Stram, D.O.4
  • 60
    • 33746414840 scopus 로고    scopus 로고
    • Two-stage designs in case-control association analysis
    • Zuo, Y. J., Zou, G. H., and Zhao, H. Y. (2006). Two-stage designs in case-control association analysis. Genetics 173, 1747-1760.
    • (2006) Genetics , vol.173 , pp. 1747-1760
    • Zuo, Y.J.1    Zou, G.H.2    Zhao, H.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.