메뉴 건너뛰기




Volumn 24, Issue 5, 2006, Pages 537-544

Gene prioritization through genomic data fusion

Author keywords

[No Author keywords available]

Indexed keywords

DATA ACQUISITION; DATABASE SYSTEMS; DISEASES; GENES; NATURAL SCIENCES; STATISTICAL METHODS;

EID: 33646568805     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1203     Document Type: Article
Times cited : (761)

References (50)
  • 1
    • 0141958996 scopus 로고    scopus 로고
    • Genomics. Microarrays - Guilt by association
    • Quackenbush, J. Genomics. Microarrays - guilt by association. Science 302, 240-241 (2004).
    • (2004) Science , vol.302 , pp. 240-241
    • Quackenbush, J.1
  • 2
    • 0037370478 scopus 로고    scopus 로고
    • Bioinformatics in the post-sequence era
    • Kanehisa, M. & Bork, P. Bioinformatics in the post-sequence era. Nat. Genet. 33 Suppl. 305-310 (2003).
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 305-310
    • Kanehisa, M.1    Bork, P.2
  • 3
    • 4444273565 scopus 로고    scopus 로고
    • Funding high-throughput data sharing
    • Ball, C.A., Sherlock, G. & Brazma, A. Funding high-throughput data sharing. Nat. Biotechnol. 22, 1179-1183 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1179-1183
    • Ball, C.A.1    Sherlock, G.2    Brazma, A.3
  • 4
    • 0037580196 scopus 로고    scopus 로고
    • A similarity-based method for genome-wide prediction of disease-relevant human genes
    • Freudenberg, J. & Propping, P. A similarity-based method for genome-wide prediction of disease-relevant human genes. Bioinformatics 18 Suppl. 2, S110-S115 (2002).
    • (2002) Bioinformatics , vol.18 , Issue.2 SUPPL.
    • Freudenberg, J.1    Propping, P.2
  • 5
    • 0036649742 scopus 로고    scopus 로고
    • Association of genes to genetically inherited diseases using data mining
    • Perez-Iratxeta, C., Bork, P. & Andrade, M.A. Association of genes to genetically inherited diseases using data mining. Nat. Genet. 31, 316-319 (2002).
    • (2002) Nat. Genet. , vol.31 , pp. 316-319
    • Perez-Iratxeta, C.1    Bork, P.2    Andrade, M.A.3
  • 6
    • 1542787787 scopus 로고    scopus 로고
    • POCUS: Mining genomic sequence annotation to predict disease genes
    • Turner, F.S., Clutterbuck, D.R. & Semple, C.A. POCUS: mining genomic sequence annotation to predict disease genes. Genome Biol. 4, R75 (2003).
    • (2003) Genome Biol. , vol.4
    • Turner, F.S.1    Clutterbuck, D.R.2    Semple, C.A.3
  • 7
    • 15044341082 scopus 로고    scopus 로고
    • Integration of text- and data-mining using ontologies successfully selects disease gene candidates
    • Tiffin, N. et al. Integration of text- and data-mining using ontologies successfully selects disease gene candidates. Nucleic Acids Res. 33, 1544-1552 (2005).
    • (2005) Nucleic Acids Res. , vol.33 , pp. 1544-1552
    • Tiffin, N.1
  • 9
    • 3543106033 scopus 로고    scopus 로고
    • Genome-wide identification of genes likely to be involved in human genetic disease
    • Lopez-Bigas, N. & Ouzounis, C.A. Genome-wide identification of genes likely to be involved in human genetic disease. Nucleic Acids Res. 32, 3108-3114 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3108-3114
    • Lopez-Bigas, N.1    Ouzounis, C.A.2
  • 10
    • 19844367341 scopus 로고    scopus 로고
    • Exploring relationships and mining data with the UCSC Gene Sorter
    • Kent, W.J. et al. Exploring relationships and mining data with the UCSC Gene Sorter. Genome Res. 15, 737-741 (2005).
    • (2005) Genome Res. , vol.15 , pp. 737-741
    • Kent, W.J.1
  • 11
    • 25444482839 scopus 로고    scopus 로고
    • PathwayVoyager: Pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database
    • Altermann, E. & Klaenhammer, T.R. PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. BMC Genomics 6, 60 (2005).
    • (2005) BMC Genomics , vol.6 , pp. 60
    • Altermann, E.1    Klaenhammer, T.R.2
  • 12
    • 23144431920 scopus 로고    scopus 로고
    • TOUCAN 2: The all-inclusive open source workbench for regulatory sequence analysis
    • Aerts, S. et al. TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis. Nucleic Acids Res. 33, W393-W396 (2005).
    • (2005) Nucleic Acids Res. , vol.33
    • Aerts, S.1
  • 13
  • 14
    • 0033027794 scopus 로고    scopus 로고
    • Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
    • Tamayo, P. et al. Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proc. Natl. Acad. Sci. USA 96, 2907-2912 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2907-2912
    • Tamayo, P.1
  • 15
    • 1442335997 scopus 로고    scopus 로고
    • Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation
    • Stegmaier, K. et al. Gene expression-based high-throughput screening (GE-HTS) and application to leukemia differentiation. Nat. Genet. 36, 257-263 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 257-263
    • Stegmaier, K.1
  • 16
    • 19444368311 scopus 로고    scopus 로고
    • BCL6 suppresses RhoA activity to alter macrophage morphology and motility
    • Pixley, F.J. et al. BCL6 suppresses RhoA activity to alter macrophage morphology and motility. J. Cell Sci. 118, 1873-1883 (2005).
    • (2005) J. Cell Sci. , vol.118 , pp. 1873-1883
    • Pixley, F.J.1
  • 17
    • 0035863786 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a regulator of monocyte-macrophage function
    • Galimi, F. et al. Hepatocyte growth factor is a regulator of monocyte-macrophage function. J. Immunol. 166, 1241-1247 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 1241-1247
    • Galimi, F.1
  • 18
    • 10344262904 scopus 로고    scopus 로고
    • Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo
    • Brown, N.J. et al. Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo. J. Immunol. 173, 7584-7593 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 7584-7593
    • Brown, N.J.1
  • 19
    • 0033753819 scopus 로고    scopus 로고
    • The 22q11 deletion syndromes
    • Scambler, P.J. The 22q11 deletion syndromes. Hum. Mol. Genet. 9, 2421-2426 (2000).
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2421-2426
    • Scambler, P.J.1
  • 20
    • 19444371444 scopus 로고    scopus 로고
    • Dissecting contiguous gene defects: TBX1
    • Baldini, A. Dissecting contiguous gene defects: TBX1. Curr. Opin. Genet. Dev. 15, 279-284 (2005).
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 279-284
    • Baldini, A.1
  • 21
    • 0035098557 scopus 로고    scopus 로고
    • DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
    • Jerome, L.A. & Papaioannou, V.E. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat. Genet. 27, 286-291 (2001).
    • (2001) Nat. Genet. , vol.27 , pp. 286-291
    • Jerome, L.A.1    Papaioannou, V.E.2
  • 22
    • 17744395906 scopus 로고    scopus 로고
    • TBX1 is responsible for cardiovascular defects in velo-cardio-facial/ DiGeorge syndrome
    • Merscher, S. et al. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell 104, 619-629 (2001).
    • (2001) Cell , vol.104 , pp. 619-629
    • Merscher, S.1
  • 23
    • 0035263599 scopus 로고    scopus 로고
    • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
    • Lindsay, E.A. et al. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 410, 97-101 (2001).
    • (2001) Nature , vol.410 , pp. 97-101
    • Lindsay, E.A.1
  • 24
    • 0142149329 scopus 로고    scopus 로고
    • The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans
    • Piotrowski, T. et al. The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development 130, 5043-5052 (2003).
    • (2003) Development , vol.130 , pp. 5043-5052
    • Piotrowski, T.1
  • 25
    • 0033071959 scopus 로고    scopus 로고
    • A novel 22q11.2 microdeletion in DiGeorge syndrome
    • Rauch, A. et al. A novel 22q11.2 microdeletion in DiGeorge syndrome. Am. J. Hum. Genet. 64, 659-666 (1999).
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 659-666
    • Rauch, A.1
  • 26
    • 0034858660 scopus 로고    scopus 로고
    • The development and evolution of the pharyngeal arches
    • Graham, A. The development and evolution of the pharyngeal arches. J. Anat. 199, 133-141 (2001).
    • (2001) J. Anat. , vol.199 , pp. 133-141
    • Graham, A.1
  • 27
    • 0037329890 scopus 로고    scopus 로고
    • VEGF: A modifier of the del22q11 (DiGeorge) syndrome?
    • Stalmans, I. et al. VEGF: a modifier of the del22q11 (DiGeorge) syndrome? Nat. Med. 9, 173-182 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 173-182
    • Stalmans, I.1
  • 28
    • 4844222294 scopus 로고    scopus 로고
    • TXTGate: Profiling gene groups with text-based information
    • Glenisson, P. et al. TXTGate: profiling gene groups with text-based information. Genome Biol. 5, R43 (2004).
    • (2004) Genome Biol. , vol.5
    • Glenisson, P.1
  • 29
    • 0037245913 scopus 로고    scopus 로고
    • BIND: The Biomolecular Interaction Network Database
    • Bader, G.D., Betel, D. & Hogue, C.W. BIND: the Biomolecular Interaction Network Database. Nucleic Acids Res. 31, 248-250 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 248-250
    • Bader, G.D.1    Betel, D.2    Hogue, C.W.3
  • 30
    • 4444292717 scopus 로고    scopus 로고
    • A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes
    • Aerts, S., Van Loo, P., Moreau, Y. & De Moor, B. A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes. Bioinformatics 20, 1974-1976 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 1974-1976
    • Aerts, S.1    Van Loo, P.2    Moreau, Y.3    De Moor, B.4
  • 31
    • 0141993704 scopus 로고    scopus 로고
    • A gene-coexpression network for global discovery of conserved genetic modules
    • Stuart, J.M., Segal, E., Koller, D. & Kim, S.K. A gene-coexpression network for global discovery of conserved genetic modules. Science 302, 249-255 (2003).
    • (2003) Science , vol.302 , pp. 249-255
    • Stuart, J.M.1    Segal, E.2    Koller, D.3    Kim, S.K.4
  • 33
    • 0032533299 scopus 로고    scopus 로고
    • The shaping of pharyngeal cartilages during early development of the zebrafish
    • Kimmel, C.B. et al. The shaping of pharyngeal cartilages during early development of the zebrafish. Dev. Biol. 203, 245-263 (1998).
    • (1998) Dev. Biol. , vol.203 , pp. 245-263
    • Kimmel, C.B.1
  • 34
    • 5344223383 scopus 로고    scopus 로고
    • Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
    • Splawski, I. et al. Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell 119, 19-31 (2004).
    • (2004) Cell , vol.119 , pp. 19-31
    • Splawski, I.1
  • 35
    • 0344406969 scopus 로고    scopus 로고
    • Missense mutations in CRELD1 are associated with cardiac atrioventricular septal defects
    • Robinson, S.W. et al. Missense mutations in CRELD1 are associated with cardiac atrioventricular septal defects. Am. J. Hum. Genet. 72, 1047-1052 (2003).
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 1047-1052
    • Robinson, S.W.1
  • 36
    • 10744220034 scopus 로고    scopus 로고
    • Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy
    • Hayashi, T. et al. Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy. Biochem. Biophys. Res. Commun. 313, 178-184 (2004).
    • (2004) Biochem. Biophys. Res. Commun. , vol.313 , pp. 178-184
    • Hayashi, T.1
  • 37
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • Zimprich, A. et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44, 601-607 (2004).
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1
  • 38
    • 20144366550 scopus 로고    scopus 로고
    • Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease
    • Zuchner, S. et al. Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease. Nat. Genet. 37, 289-294 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 289-294
    • Zuchner, S.1
  • 39
    • 4143084861 scopus 로고    scopus 로고
    • Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS
    • Munch, C. et al. Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology 63, 724-726 (2004).
    • (2004) Neurology , vol.63 , pp. 724-726
    • Munch, C.1
  • 40
    • 10744223472 scopus 로고    scopus 로고
    • Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome
    • Tian, X.L. et al. Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature 427, 640-645 (2004).
    • (2004) Nature , vol.427 , pp. 640-645
    • Tian, X.L.1
  • 41
    • 12144290256 scopus 로고    scopus 로고
    • ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating
    • Bienengraeber, M. et al. ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating. Nat. Genet. 36, 382-387 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 382-387
    • Bienengraeber, M.1
  • 42
    • 10744229057 scopus 로고    scopus 로고
    • Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome
    • Windpassinger, C. et al. Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome. Nat. Genet. 36, 271-276 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 271-276
    • Windpassinger, C.1
  • 43
    • 2642565901 scopus 로고    scopus 로고
    • NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome
    • Tonkin, E.T., Wang, T.J., Lisgo, S., Bamshad, M.J. & Strachan, T. NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome. Nat. Genet. 36, 636-641 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 636-641
    • Tonkin, E.T.1    Wang, T.J.2    Lisgo, S.3    Bamshad, M.J.4    Strachan, T.5
  • 44
    • 0035877214 scopus 로고    scopus 로고
    • Exclusion of linkage to the CDL1 gene region on chromosome 3q26.3 in some familial cases of Cornelia de Lange syndrome
    • Krantz, I.D. et al. Exclusion of linkage to the CDL1 gene region on chromosome 3q26.3 in some familial cases of Cornelia de Lange syndrome. Am. J. Med. Genet. 101, 120-129 (2001).
    • (2001) Am. J. Med. Genet. , vol.101 , pp. 120-129
    • Krantz, I.D.1
  • 45
    • 20144386616 scopus 로고    scopus 로고
    • Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
    • Wang, X. et al. Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nat. Genet. 37, 365-372 (2005).
    • (2005) Nat. Genet. , vol.37 , pp. 365-372
    • Wang, X.1
  • 46
    • 2442585704 scopus 로고    scopus 로고
    • Functional variants of OCTN cation transporter genes are associated with Crohn disease
    • Peltekova, V.D. et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat. Genet. 36, 471-475 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 471-475
    • Peltekova, V.D.1
  • 47
    • 7444237665 scopus 로고    scopus 로고
    • Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews
    • Aharon-Peretz, J., Rosenbaum, H. & Gershoni-Baruch, R. Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews. N. Engl. J. Med. 351, 1972-1977 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1972-1977
    • Aharon-Peretz, J.1    Rosenbaum, H.2    Gershoni-Baruch, R.3
  • 48
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich, A.B. et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am. J. Hum. Genet. 75, 330-337 (2004).
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 330-337
    • Begovich, A.B.1
  • 49
    • 10744220794 scopus 로고    scopus 로고
    • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
    • Helgadottir, A. et al. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat. Genet. 36, 233-239 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 233-239
    • Helgadottir, A.1
  • 50
    • 20044362721 scopus 로고    scopus 로고
    • Family-based association between Alzheimer's disease and variants in UBQLN1
    • Bertram, L. et al. Family-based association between Alzheimer's disease and variants in UBQLN1. N. Engl. J. Med. 352, 884-894 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 884-894
    • Bertram, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.