-
1
-
-
0037370311
-
Natural variation in human gene expression assessed in lymphoblastoid cells
-
Cheung, V.G. et al. Natural variation in human gene expression assessed in lymphoblastoid cells. Nat. Genet. 33, 422-425 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 422-425
-
-
Cheung, V.G.1
-
2
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem, R.B., Yvert, G., Clinton, R. & Kruglyak, L. Genetic dissection of transcriptional regulation in budding yeast. Science 296, 752-755 (2002).
-
(2002)
Science
, vol.296
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
3
-
-
0042856391
-
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors
-
Yvert, G. et al. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nat. Genet. 35, 57-64 (2003).
-
(2003)
Nat. Genet.
, vol.35
, pp. 57-64
-
-
Yvert, G.1
-
4
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt, E.E. et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 422, 297-302 (2003).
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
-
5
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley, M. et al. Genetic analysis of genome-wide variation in human gene expression. Nature 430, 743-747 (2004).
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
-
6
-
-
0036250938
-
Rat genetics: Attaching physiology and pharmacology to the genome
-
Jacob, H.J. & Kwitek, A.E. Rat genetics: attaching physiology and pharmacology to the genome. Nat. Rev. Genet. 3, 33-42 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 33-42
-
-
Jacob, H.J.1
Kwitek, A.E.2
-
8
-
-
1842684068
-
Genome sequence of the Brown Norway rat yields insights into mammalian evolution
-
Gibbs, R.A. et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 428, 493-521 (2004).
-
(2004)
Nature
, vol.428
, pp. 493-521
-
-
Gibbs, R.A.1
-
10
-
-
0027305652
-
Insulin resistance in spontaneously hypertensive rats: Difference in interpretation based on insulin infusion rate or on plasma insulin in glucose clamp studies
-
Rao, R.H. Insulin resistance in spontaneously hypertensive rats: difference in interpretation based on insulin infusion rate or on plasma insulin in glucose clamp studies. Diabetes 42, 1364-1371 (1993).
-
(1993)
Diabetes
, vol.42
, pp. 1364-1371
-
-
Rao, R.H.1
-
11
-
-
0027475259
-
Insulin resistance in the conscious spontaneously hypertensive rat: Euglycemic hyperinsulinemic clamp study
-
Hulman, S., Falkner, B. & Freyvogel, N. Insulin resistance in the conscious spontaneously hypertensive rat: euglycemic hyperinsulinemic clamp study. Metabolism 42, 14-18 (1993).
-
(1993)
Metabolism
, vol.42
, pp. 14-18
-
-
Hulman, S.1
Falkner, B.2
Freyvogel, N.3
-
12
-
-
0030900338
-
Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats
-
Aitman, T.J. et al. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Nat. Genet. 16, 197-201 (1997).
-
(1997)
Nat. Genet.
, vol.16
, pp. 197-201
-
-
Aitman, T.J.1
-
13
-
-
0842277242
-
Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
-
Grundy, S.M., Brewer, H.B. Jr., Cleeman, J.I., Smith, S.C. Jr. & Lenfant, C. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/ American Heart Association conference on scientific issues related to definition. Circulation 109, 433-438 (2004).
-
(2004)
Circulation
, vol.109
, pp. 433-438
-
-
Grundy, S.M.1
Brewer Jr., H.B.2
Cleeman, J.I.3
Smith Jr., S.C.4
Lenfant, C.5
-
14
-
-
0024517658
-
An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains
-
Pravenec, M., Klir, P., Kren, V., Zicha, J. & Kunes, J. An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains. J. Hypertens. 7, 217-221 (1989).
-
(1989)
J. Hypertens.
, vol.7
, pp. 217-221
-
-
Pravenec, M.1
Klir, P.2
Kren, V.3
Zicha, J.4
Kunes, J.5
-
15
-
-
2342507607
-
Genetic analysis of metabolic syndrome in the spontaneously hypertensive rat
-
Pravenec, M. et al. Genetic analysis of metabolic syndrome in the spontaneously hypertensive rat. Physiol. Res. 53 (Suppl 1), 15-23 (2004).
-
(2004)
Physiol. Res.
, vol.53
, Issue.SUPPL. 1
, pp. 15-23
-
-
Pravenec, M.1
-
17
-
-
0346294232
-
Application of chromosomal substitution techniques in gene-function discovery
-
Cowley, A.W. Jr., Roman, R.J. & Jacob, H.J. Application of chromosomal substitution techniques in gene-function discovery. J. Physiol. 554, 46-55 (2004).
-
(2004)
J. Physiol.
, vol.554
, pp. 46-55
-
-
Cowley Jr., A.W.1
Roman, R.J.2
Jacob, H.J.3
-
18
-
-
11144355685
-
Genetic dissection of complex traits with chromosome substitution strains of mice
-
Singer, J.B. et al. Genetic dissection of complex traits with chromosome substitution strains of mice. Science 304, 445-448 (2004).
-
(2004)
Science
, vol.304
, pp. 445-448
-
-
Singer, J.B.1
-
19
-
-
0029878553
-
Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains
-
Belknap, J.K., Mitchell, S.R., O'Toole, L.A., Helms, M.L & Crabbe, J.C. Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains. Behav. Genet. 26, 149-160 (1996).
-
(1996)
Behav. Genet.
, vol.26
, pp. 149-160
-
-
Belknap, J.K.1
Mitchell, S.R.2
O'Toole, L.A.3
Helms, M.L.4
Crabbe, J.C.5
-
20
-
-
10744225849
-
A SNP map of the rat genome generated from cDNA sequences
-
Zimdahl, H. et al. A SNP map of the rat genome generated from cDNA sequences. Science 303, 807 (2004).
-
(2004)
Science
, vol.303
, pp. 807
-
-
Zimdahl, H.1
-
21
-
-
0037146578
-
Finding genes that underlie complex traits
-
Glazier, A.M., Nadeau, J.H. & Aitman, T.J. Finding genes that underlie complex traits. Science 298, 2345-2349 (2002).
-
(2002)
Science
, vol.298
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
22
-
-
0242291131
-
The nature and identification of quantitative trait loci: A community's view
-
Abiola, O. et al. The nature and identification of quantitative trait loci: a community's view. Nat. Rev. Genet. 4, 911-916 (2003).
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 911-916
-
-
Abiola, O.1
-
23
-
-
0032958470
-
Identification of Cd36(Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
-
Aitman, T.J. et al. Identification of Cd36(Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat. Genet. 21, 76-83 (1999).
-
(1999)
Nat. Genet.
, vol.21
, pp. 76-83
-
-
Aitman, T.J.1
-
24
-
-
17744390348
-
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
-
Berge, K.E. et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290, 1771-1775 (2000).
-
(2000)
Science
, vol.290
, pp. 1771-1775
-
-
Berge, K.E.1
-
25
-
-
0032725185
-
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway
-
Lawn, R.M. et al. The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J. Clin. Invest. 104, R25-R31 (1999).
-
(1999)
J. Clin. Invest.
, vol.104
-
-
Lawn, R.M.1
-
26
-
-
5944254200
-
Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
-
Karp, C.L. et al. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat. Immunol. 1, 221-226 (2000).
-
(2000)
Nat. Immunol.
, vol.1
, pp. 221-226
-
-
Karp, C.L.1
-
27
-
-
0036146622
-
Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism
-
Glazier, A.M., Scott, J. & Aitman, T.J. Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism. Mamm. Genome 13, 108-113 (2002).
-
(2002)
Mamm. Genome.
, vol.13
, pp. 108-113
-
-
Glazier, A.M.1
Scott, J.2
Aitman, T.J.3
-
28
-
-
0035400051
-
Genetical Genomics: The added value from segregation
-
Jansen, R.C. & Nap, J.-P. Genetical Genomics: the added value from segregation. Trends Genet. 17, 388-391 (2001).
-
(2001)
Trends Genet.
, vol.17
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.-P.2
-
29
-
-
0031751636
-
Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains
-
Frantz, S.A. et al. Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains. Hypertension 32, 639-646 (1998).
-
(1998)
Hypertension
, vol.32
, pp. 639-646
-
-
Frantz, S.A.1
-
30
-
-
0344378202
-
Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1
-
Hubner, N., Lee, Y.A., Lindpaintner, K., Ganten, D. & Kreutz, R. Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1. Hypertension 34, 643-648 (1999).
-
(1999)
Hypertension
, vol.34
, pp. 643-648
-
-
Hubner, N.1
Lee, Y.A.2
Lindpaintner, K.3
Ganten, D.4
Kreutz, R.5
-
31
-
-
0035570186
-
Genetic dissection of region around the Sa gene on rat chromosome 1: Evidence for multiple loci affecting blood pressure
-
Frantz, S., Clemitson, J.R., Bihoreau, M.T., Gauguier, D. & Samani, N.J. Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure. Hypertension 38, 216-221 (2001).
-
(2001)
Hypertension
, vol.38
, pp. 216-221
-
-
Frantz, S.1
Clemitson, J.R.2
Bihoreau, M.T.3
Gauguier, D.4
Samani, N.J.5
-
32
-
-
0031577173
-
Novel quantitative trait loci for blood pressure and related traits on rat chromosomes 1, 10, and 18
-
Kovacs, P., Voigt, B. & Kloting, I. Novel quantitative trait loci for blood pressure and related traits on rat chromosomes 1, 10, and 18. Biochem. Biophys. Res. Commun. 235, 343-348 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 343-348
-
-
Kovacs, P.1
Voigt, B.2
Kloting, I.3
-
33
-
-
25744440785
-
Genetic isolation of a quantitative trait locus on chromosome 18 associated with blood pressure and salt sensitivity in the SHR
-
Pravenec, M., Zidek, V., Kren, V., St Lezin, E. & Kurtz, T.W. Genetic isolation of a quantitative trait locus on chromosome 18 associated with blood pressure and salt sensitivity in the SHR. Am. J. Hypertens. 14, 82A (2001).
-
(2001)
Am. J. Hypertens.
, vol.14
-
-
Pravenec, M.1
Zidek, V.2
Kren, V.3
St Lezin, E.4
Kurtz, T.W.5
-
34
-
-
0026675062
-
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
-
Cambien, F. et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359, 641-644 (1992).
-
(1992)
Nature
, vol.359
, pp. 641-644
-
-
Cambien, F.1
-
35
-
-
0028930348
-
A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease
-
Lindpaintner, K. et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N. Engl. J. Med. 332, 706-711 (1995).
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 706-711
-
-
Lindpaintner, K.1
-
36
-
-
0035134739
-
Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats
-
Pravenec, M. et al. Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Nat. Genet. 27, 156-158 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 156-158
-
-
Pravenec, M.1
-
37
-
-
0037340133
-
Microarray analysis of rat chromosome 2 congenic strains
-
McBride, M.W. et al. Microarray analysis of rat chromosome 2 congenic strains. Hypertension 41, 847-853 (2003).
-
(2003)
Hypertension
, vol.41
, pp. 847-853
-
-
McBride, M.W.1
-
38
-
-
0034680349
-
Genome-wide linkage analysis of systolic and diastolic blood pressure: The Quebec Family Study
-
Rice, T. et al. Genome-wide linkage analysis of systolic and diastolic blood pressure: the Quebec Family Study. Circulation 102, 1956-1963 (2000).
-
(2000)
Circulation
, vol.102
, pp. 1956-1963
-
-
Rice, T.1
-
39
-
-
0041461913
-
A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set
-
Jirout, M. et al. A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set. Mamm. Genome 14, 537-546 (2003).
-
(2003)
Mamm. Genome.
, vol.14
, pp. 537-546
-
-
Jirout, M.1
-
40
-
-
0032813954
-
Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats
-
Kato, N. et al. Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats. Mamm, Genome 10, 259-265 (1999).
-
(1999)
Mamm. Genome.
, vol.10
, pp. 259-265
-
-
Kato, N.1
-
41
-
-
0028863507
-
Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains
-
Pravenec, M. et al. Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains. J. Clin. Invest. 96, 1973-1978 (1995).
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1973-1978
-
-
Pravenec, M.1
-
42
-
-
10244221216
-
Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat
-
Bottger, A. et al. Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat. J. Clin. Invest. 98, 856-862 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 856-862
-
-
Bottger, A.1
-
43
-
-
0037840360
-
Genetic Models in Applied Physiology. HXB/BXH rat recombinant inbred strain platform: A newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics
-
Printz, M.P., Jirout, M., Jaworski, R., Alemayehu, A. & Kren, V. Genetic Models in Applied Physiology. HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics. J. Appl. Physiol. 94, 2510-2522 (2003).
-
(2003)
J. Appl. Physiol.
, vol.94
, pp. 2510-2522
-
-
Printz, M.P.1
Jirout, M.2
Jaworski, R.3
Alemayehu, A.4
Kren, V.5
-
44
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry, R.A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
-
45
-
-
0023426747
-
MAPMAKER-an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
-
Lander, E.S. et al. MAPMAKER-an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1, 174-181 (1987).
-
(1987)
Genomics
, vol.1
, pp. 174-181
-
-
Lander, E.S.1
-
46
-
-
0030074265
-
A genetic linkage map of the rat derived from recombinant inbred strains
-
Pravenec, M. et al. A genetic linkage map of the rat derived from recombinant inbred strains. Mamm. Genome 7, 117-127 (1996).
-
(1996)
Mamm. Genome.
, vol.7
, pp. 117-127
-
-
Pravenec, M.1
-
47
-
-
0032875009
-
HXB/lpcv and BXH/Cub recombinant inbred strains of the rat: Strain distribution patterns of 632 alleles
-
Pravenec, M. et al. HXB/lpcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles. Folia Biol. (Praha) 45, 203-215 (1999).
-
(1999)
Folia Biol. (Praha)
, vol.45
, pp. 203-215
-
-
Pravenec, M.1
-
48
-
-
0028151261
-
Empirical threshold values for quantitative trait mapping
-
Churchill, G.A. & Doerge, R.W. Empirical threshold values for quantitative trait mapping. Genetics 138, 963-971 (1994).
-
(1994)
Genetics
, vol.138
, pp. 963-971
-
-
Churchill, G.A.1
Doerge, R.W.2
-
49
-
-
0036020892
-
A direct approach to false discovery rates
-
Storey, J.D. A direct approach to false discovery rates. J. R. Stat Soc (B) 64, 479-498 (2002).
-
(2002)
J. R. Stat Soc (B)
, vol.64
, pp. 479-498
-
-
Storey, J.D.1
-
50
-
-
0033596973
-
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings
-
Krushkal, J. et al. Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation 99, 1407-1410 (1999).
-
(1999)
Circulation
, vol.99
, pp. 1407-1410
-
-
Krushkal, J.1
|