메뉴 건너뛰기




Volumn 49, Issue 3, 2013, Pages 399-410

The Tangled Circuitry of Metabolism and Apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 2; CYTOCHROME C; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLUCOSE TRANSPORTER; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN NOXA; PROTEIN P53; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIRTUIN;

EID: 84873462599     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.12.026     Document Type: Review
Times cited : (101)

References (115)
  • 3
    • 33745006592 scopus 로고    scopus 로고
    • The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
    • Alves N.L., Derks I.A., Berk E., Spijker R., van Lier R.A., Eldering E. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 2006, 24:703-716.
    • (2006) Immunity , vol.24 , pp. 703-716
    • Alves, N.L.1    Derks, I.A.2    Berk, E.3    Spijker, R.4    van Lier, R.A.5    Eldering, E.6
  • 5
    • 0037147239 scopus 로고    scopus 로고
    • Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature
    • Basañez G., Sharpe J.C., Galanis J., Brandt T.B., Hardwick J.M., Zimmerberg J. Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. J. Biol. Chem. 2002, 277:49360-49365.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49360-49365
    • Basañez, G.1    Sharpe, J.C.2    Galanis, J.3    Brandt, T.B.4    Hardwick, J.M.5    Zimmerberg, J.6
  • 8
    • 77955443309 scopus 로고    scopus 로고
    • Nampt/PBEF/visfatin and cancer
    • Bi T.Q., Che X.M. Nampt/PBEF/visfatin and cancer. Cancer Biol. Ther. 2010, 10:119-125.
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 119-125
    • Bi, T.Q.1    Che, X.M.2
  • 9
    • 33745739717 scopus 로고    scopus 로고
    • Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death
    • Bonzon C., Bouchier-Hayes L., Pagliari L.J., Green D.R., Newmeyer D.D. Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death. Mol. Biol. Cell 2006, 17:2150-2157.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 2150-2157
    • Bonzon, C.1    Bouchier-Hayes, L.2    Pagliari, L.J.3    Green, D.R.4    Newmeyer, D.D.5
  • 11
    • 77955135238 scopus 로고    scopus 로고
    • The role of caspase-2 in stress-induced apoptosis
    • Bouchier-Hayes L. The role of caspase-2 in stress-induced apoptosis. J. Cell. Mol. Med. 2010, 14(6A):1212-1224.
    • (2010) J. Cell. Mol. Med. , vol.14 , Issue.6 A , pp. 1212-1224
    • Bouchier-Hayes, L.1
  • 13
    • 46349098382 scopus 로고    scopus 로고
    • Regulation of apoptosis by the redox state of cytochrome c
    • Brown G.C., Borutaite V. Regulation of apoptosis by the redox state of cytochrome c. Biochim. Biophys. Acta 2008, 1777:877-881.
    • (2008) Biochim. Biophys. Acta , vol.1777 , pp. 877-881
    • Brown, G.C.1    Borutaite, V.2
  • 16
    • 84859977895 scopus 로고    scopus 로고
    • Sirtuins mediate mammalian metabolic responses to nutrient availability
    • Chalkiadaki A., Guarente L. Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat. Rev. Endocrinol. 2012, 8:287-296.
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 287-296
    • Chalkiadaki, A.1    Guarente, L.2
  • 20
    • 84857873334 scopus 로고    scopus 로고
    • Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis
    • Chipuk J.E., McStay G.P., Bharti A., Kuwana T., Clarke C.J., Siskind L.J., Obeid L.M., Green D.R. Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis. Cell 2012, 148:988-1000.
    • (2012) Cell , vol.148 , pp. 988-1000
    • Chipuk, J.E.1    McStay, G.P.2    Bharti, A.3    Kuwana, T.4    Clarke, C.J.5    Siskind, L.J.6    Obeid, L.M.7    Green, D.R.8
  • 22
    • 75349111140 scopus 로고    scopus 로고
    • Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
    • Cimen H., Han M.J., Yang Y., Tong Q., Koc H., Koc E.C. Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 2010, 49:304-311.
    • (2010) Biochemistry , vol.49 , pp. 304-311
    • Cimen, H.1    Han, M.J.2    Yang, Y.3    Tong, Q.4    Koc, H.5    Koc, E.C.6
  • 23
    • 0015500271 scopus 로고
    • The management of nicotinamide and nicotinic acid in the mouse
    • Collins P.B., Chaykin S. The management of nicotinamide and nicotinic acid in the mouse. J. Biol. Chem. 1972, 247:778-783.
    • (1972) J. Biol. Chem. , vol.247 , pp. 778-783
    • Collins, P.B.1    Chaykin, S.2
  • 24
    • 77953811195 scopus 로고    scopus 로고
    • Ceramide channels and their role in mitochondria-mediated apoptosis
    • Colombini M. Ceramide channels and their role in mitochondria-mediated apoptosis. Biochim. Biophys. Acta 2010, 1797:1239-1244.
    • (2010) Biochim. Biophys. Acta , vol.1797 , pp. 1239-1244
    • Colombini, M.1
  • 27
    • 68149107692 scopus 로고    scopus 로고
    • BAD: undertaker by night, candyman by day
    • Danial N.N. BAD: undertaker by night, candyman by day. Oncogene 2008, 27(Suppl 1):S53-S70.
    • (2008) Oncogene , vol.27 , Issue.SUPPL 1
    • Danial, N.N.1
  • 29
    • 0033635235 scopus 로고    scopus 로고
    • 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
    • Datta S.R., Katsov A., Hu L., Petros A., Fesik S.W., Yaffe M.B., Greenberg M.E. 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol. Cell 2000, 6:41-51.
    • (2000) Mol. Cell , vol.6 , pp. 41-51
    • Datta, S.R.1    Katsov, A.2    Hu, L.3    Petros, A.4    Fesik, S.W.5    Yaffe, M.B.6    Greenberg, M.E.7
  • 31
    • 33644859410 scopus 로고    scopus 로고
    • Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
    • Delivani P., Adrain C., Taylor R.C., Duriez P.J., Martin S.J. Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Mol. Cell 2006, 21:761-773.
    • (2006) Mol. Cell , vol.21 , pp. 761-773
    • Delivani, P.1    Adrain, C.2    Taylor, R.C.3    Duriez, P.J.4    Martin, S.J.5
  • 32
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • del Peso L., González-García M., Page C., Herrera R., Nuñez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997, 278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • del Peso, L.1    González-García, M.2    Page, C.3    Herrera, R.4    Nuñez, G.5
  • 37
    • 79958206937 scopus 로고    scopus 로고
    • Franklin H. Epstein Lecture: sirtuins, aging, and medicine
    • Guarente L. Franklin H. Epstein Lecture: sirtuins, aging, and medicine. N. Engl. J. Med. 2011, 364:2235-2244.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2235-2244
    • Guarente, L.1
  • 38
    • 0030915095 scopus 로고    scopus 로고
    • Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis
    • Harvey N.L., Butt A.J., Kumar S. Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis. J. Biol. Chem. 1997, 272:13134-13139.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13134-13139
    • Harvey, N.L.1    Butt, A.J.2    Kumar, S.3
  • 41
    • 77952212178 scopus 로고    scopus 로고
    • Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
    • Hu W., Zhang C., Wu R., Sun Y., Levine A., Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc. Natl. Acad. Sci. USA 2010, 107:7455-7460.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 7455-7460
    • Hu, W.1    Zhang, C.2    Wu, R.3    Sun, Y.4    Levine, A.5    Feng, Z.6
  • 42
    • 77955271289 scopus 로고    scopus 로고
    • The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity
    • Huang C.R., Yang-Yen H.F. The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity. FEBS Lett. 2010, 584:3323-3330.
    • (2010) FEBS Lett. , vol.584 , pp. 3323-3330
    • Huang, C.R.1    Yang-Yen, H.F.2
  • 44
    • 63149089930 scopus 로고    scopus 로고
    • The NAD World: a new systemic regulatory network for metabolism and aging-Sirt1, systemic NAD biosynthesis, and their importance
    • Imai S. The NAD World: a new systemic regulatory network for metabolism and aging-Sirt1, systemic NAD biosynthesis, and their importance. Cell Biochem. Biophys. 2009, 53:65-74.
    • (2009) Cell Biochem. Biophys. , vol.53 , pp. 65-74
    • Imai, S.1
  • 49
    • 43049139541 scopus 로고    scopus 로고
    • P53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
    • Kawauchi K., Araki K., Tobiume K., Tanaka N. p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat. Cell Biol. 2008, 10:611-618.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 611-618
    • Kawauchi, K.1    Araki, K.2    Tobiume, K.3    Tanaka, N.4
  • 51
    • 33847263913 scopus 로고    scopus 로고
    • Bax affects production of reactive oxygen by the mitochondria of non-apoptotic neurons
    • Kirkland R.A., Franklin J.L. Bax affects production of reactive oxygen by the mitochondria of non-apoptotic neurons. Exp. Neurol. 2007, 204:458-461.
    • (2007) Exp. Neurol. , vol.204 , pp. 458-461
    • Kirkland, R.A.1    Franklin, J.L.2
  • 53
    • 69849101403 scopus 로고    scopus 로고
    • Caspase-2: killer, savior and safeguard-emerging versatile roles for an ill-defined caspase
    • Krumschnabel G., Manzl C., Villunger A. Caspase-2: killer, savior and safeguard-emerging versatile roles for an ill-defined caspase. Oncogene 2009, 28:3093-3096.
    • (2009) Oncogene , vol.28 , pp. 3093-3096
    • Krumschnabel, G.1    Manzl, C.2    Villunger, A.3
  • 55
    • 70549097114 scopus 로고    scopus 로고
    • Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?
    • Kumar S. Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?. Nat. Rev. Cancer 2009, 9:897-903.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 897-903
    • Kumar, S.1
  • 57
    • 79960141848 scopus 로고    scopus 로고
    • Mammalian sirtuins and energy metabolism
    • Li X., Kazgan N. Mammalian sirtuins and energy metabolism. Int. J. Biol. Sci. 2011, 7:575-587.
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 575-587
    • Li, X.1    Kazgan, N.2
  • 58
    • 40449102725 scopus 로고    scopus 로고
    • Redox state of cytochrome c regulates cellular ROS and caspase cascade in permeablized cell model
    • Li M., Wang A.J., Xu J.X. Redox state of cytochrome c regulates cellular ROS and caspase cascade in permeablized cell model. Protein Pept. Lett. 2008, 15:200-205.
    • (2008) Protein Pept. Lett. , vol.15 , pp. 200-205
    • Li, M.1    Wang, A.J.2    Xu, J.X.3
  • 59
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
    • Liu X., Kim C.N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996, 86:147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 62
    • 80054765894 scopus 로고    scopus 로고
    • A molecular switch that governs mitochondrial fusion and fission mediated by the BCL2-like protein CED-9 of Caenorhabditis elegans
    • Lu Y., Rolland S.G., Conradt B. A molecular switch that governs mitochondrial fusion and fission mediated by the BCL2-like protein CED-9 of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2011, 108:E813-E822.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108
    • Lu, Y.1    Rolland, S.G.2    Conradt, B.3
  • 63
    • 0035913911 scopus 로고    scopus 로고
    • Negative control of p53 by Sir2alpha promotes cell survival under stress
    • Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001, 107:137-148.
    • (2001) Cell , vol.107 , pp. 137-148
    • Luo, J.1    Nikolaev, A.Y.2    Imai, S.3    Chen, D.4    Su, F.5    Shiloh, A.6    Guarente, L.7    Gu, W.8
  • 64
  • 65
    • 79960230433 scopus 로고    scopus 로고
    • Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics
    • Martinou J.C., Youle R.J. Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. Dev. Cell 2011, 21:92-101.
    • (2011) Dev. Cell , vol.21 , pp. 92-101
    • Martinou, J.C.1    Youle, R.J.2
  • 66
    • 79952703288 scopus 로고    scopus 로고
    • Cell metabolism: an essential link between cell growth and apoptosis
    • Mason E.F., Rathmell J.C. Cell metabolism: an essential link between cell growth and apoptosis. Biochim. Biophys. Acta 2011, 1813:645-654.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 645-654
    • Mason, E.F.1    Rathmell, J.C.2
  • 68
    • 0031993196 scopus 로고    scopus 로고
    • The mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells
    • Matsuyama S., Xu Q., Velours J., Reed J.C. The mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells. Mol. Cell 1998, 1:327-336.
    • (1998) Mol. Cell , vol.1 , pp. 327-336
    • Matsuyama, S.1    Xu, Q.2    Velours, J.3    Reed, J.C.4
  • 69
    • 33644855216 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
    • Maurer U., Charvet C., Wagman A.S., Dejardin E., Green D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol. Cell 2006, 21:749-760.
    • (2006) Mol. Cell , vol.21 , pp. 749-760
    • Maurer, U.1    Charvet, C.2    Wagman, A.S.3    Dejardin, E.4    Green, D.R.5
  • 70
    • 0033199565 scopus 로고    scopus 로고
    • Oocyte apoptosis: like sand through an hourglass
    • Morita Y., Tilly J.L. Oocyte apoptosis: like sand through an hourglass. Dev. Biol. 1999, 213:1-17.
    • (1999) Dev. Biol. , vol.213 , pp. 1-17
    • Morita, Y.1    Tilly, J.L.2
  • 72
    • 34547098165 scopus 로고    scopus 로고
    • Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation
    • North B.J., Verdin E. Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation. J. Biol. Chem. 2007, 282:19546-19555.
    • (2007) J. Biol. Chem. , vol.282 , pp. 19546-19555
    • North, B.J.1    Verdin, E.2
  • 73
    • 26244453715 scopus 로고    scopus 로고
    • Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2
    • Nutt L.K., Margolis S.S., Jensen M., Herman C.E., Dunphy W.G., Rathmell J.C., Kornbluth S. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell 2005, 123:89-103.
    • (2005) Cell , vol.123 , pp. 89-103
    • Nutt, L.K.1    Margolis, S.S.2    Jensen, M.3    Herman, C.E.4    Dunphy, W.G.5    Rathmell, J.C.6    Kornbluth, S.7
  • 75
    • 0033257077 scopus 로고    scopus 로고
    • Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system
    • Okamura S., Ng C.C., Koyama K., Takei Y., Arakawa H., Monden M., Nakamura Y. Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system. Oncol. Res. 1999, 11:281-285.
    • (1999) Oncol. Res. , vol.11 , pp. 281-285
    • Okamura, S.1    Ng, C.C.2    Koyama, K.3    Takei, Y.4    Arakawa, H.5    Monden, M.6    Nakamura, Y.7
  • 78
  • 81
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • Revollo J.R., Grimm A.A., Imai S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J. Biol. Chem. 2004, 279:50754-50763.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.3
  • 82
  • 85
    • 78649833334 scopus 로고    scopus 로고
    • P53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
    • Scherz-Shouval R., Weidberg H., Gonen C., Wilder S., Elazar Z., Oren M. p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc. Natl. Acad. Sci. USA 2010, 107:18511-18516.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 18511-18516
    • Scherz-Shouval, R.1    Weidberg, H.2    Gonen, C.3    Wilder, S.4    Elazar, Z.5    Oren, M.6
  • 86
    • 1942506067 scopus 로고    scopus 로고
    • The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
    • Schwartzenberg-Bar-Yoseph F., Armoni M., Karnieli E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res. 2004, 64:2627-2633.
    • (2004) Cancer Res. , vol.64 , pp. 2627-2633
    • Schwartzenberg-Bar-Yoseph, F.1    Armoni, M.2    Karnieli, E.3
  • 87
    • 84863720396 scopus 로고    scopus 로고
    • Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice
    • Shalini S., Dorstyn L., Wilson C., Puccini J., Ho L., Kumar S. Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice. Cell Death Differ. 2012, 19:1370-1380.
    • (2012) Cell Death Differ. , vol.19 , pp. 1370-1380
    • Shalini, S.1    Dorstyn, L.2    Wilson, C.3    Puccini, J.4    Ho, L.5    Kumar, S.6
  • 88
    • 49349105966 scopus 로고    scopus 로고
    • Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome c release
    • Sheridan C., Delivani P., Cullen S.P., Martin S.J. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome c release. Mol. Cell 2008, 31:570-585.
    • (2008) Mol. Cell , vol.31 , pp. 570-585
    • Sheridan, C.1    Delivani, P.2    Cullen, S.P.3    Martin, S.J.4
  • 89
    • 78651468722 scopus 로고    scopus 로고
    • Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
    • Someya S., Yu W., Hallows W.C., Xu J., Vann J.M., Leeuwenburgh C., Tanokura M., Denu J.M., Prolla T.A. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010, 143:802-812.
    • (2010) Cell , vol.143 , pp. 802-812
    • Someya, S.1    Yu, W.2    Hallows, W.C.3    Xu, J.4    Vann, J.M.5    Leeuwenburgh, C.6    Tanokura, M.7    Denu, J.M.8    Prolla, T.A.9
  • 91
    • 79551648970 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
    • Strub G.M., Paillard M., Liang J., Gomez L., Allegood J.C., Hait N.C., Maceyka M., Price M.M., Chen Q., Simpson D.C., et al. Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration. FASEB J. 2011, 25:600-612.
    • (2011) FASEB J. , vol.25 , pp. 600-612
    • Strub, G.M.1    Paillard, M.2    Liang, J.3    Gomez, L.4    Allegood, J.C.5    Hait, N.C.6    Maceyka, M.7    Price, M.M.8    Chen, Q.9    Simpson, D.C.10
  • 93
    • 0034682812 scopus 로고    scopus 로고
    • BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
    • Tan Y., Demeter M.R., Ruan H., Comb M.J. BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival. J. Biol. Chem. 2000, 275:25865-25869.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25865-25869
    • Tan, Y.1    Demeter, M.R.2    Ruan, H.3    Comb, M.J.4
  • 94
    • 78751482244 scopus 로고    scopus 로고
    • Bcl-2 proteins and autophagy regulate mitochondrial dynamics during programmed cell death in the Drosophila ovary
    • Tanner E.A., Blute T.A., Brachmann C.B., McCall K. Bcl-2 proteins and autophagy regulate mitochondrial dynamics during programmed cell death in the Drosophila ovary. Development 2011, 138:327-338.
    • (2011) Development , vol.138 , pp. 327-338
    • Tanner, E.A.1    Blute, T.A.2    Brachmann, C.B.3    McCall, K.4
  • 98
    • 84863009089 scopus 로고    scopus 로고
    • The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death
    • Van Brocklyn J.R., Williams J.B. The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 2012, 163:26-36.
    • (2012) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.163 , pp. 26-36
    • Van Brocklyn, J.R.1    Williams, J.B.2
  • 99
    • 0035380462 scopus 로고    scopus 로고
    • Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
    • Vander Heiden M.G., Li X.X., Gottleib E., Hill R.B., Thompson C.B., Colombini M. Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J. Biol. Chem. 2001, 276:19414-19419.
    • (2001) J. Biol. Chem. , vol.276 , pp. 19414-19419
    • Vander Heiden, M.G.1    Li, X.X.2    Gottleib, E.3    Hill, R.B.4    Thompson, C.B.5    Colombini, M.6
  • 100
    • 57049132739 scopus 로고    scopus 로고
    • Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
    • Vaughn A.E., Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nat. Cell Biol. 2008, 10:1477-1483.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1477-1483
    • Vaughn, A.E.1    Deshmukh, M.2
  • 102
    • 84875622163 scopus 로고    scopus 로고
    • Sirtuin-3 modulates Bak/Bax dependent apoptosis
    • Published online October 29, 2012
    • Verma M., Shulga N., Pastorino J.G. Sirtuin-3 modulates Bak/Bax dependent apoptosis. J. Cell Sci. 2012, Published online October 29, 2012. 10.1242/jcs.115188.
    • (2012) J. Cell Sci.
    • Verma, M.1    Shulga, N.2    Pastorino, J.G.3
  • 103
    • 34447626095 scopus 로고    scopus 로고
    • SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
    • Wang F., Nguyen M., Qin F.X., Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 2007, 6:505-514.
    • (2007) Aging Cell , vol.6 , pp. 505-514
    • Wang, F.1    Nguyen, M.2    Qin, F.X.3    Tong, Q.4
  • 104
    • 84858796367 scopus 로고    scopus 로고
    • A two-way street: reciprocal regulation of metabolism and signalling
    • Wellen K.E., Thompson C.B. A two-way street: reciprocal regulation of metabolism and signalling. Nat. Rev. Mol. Cell Biol. 2012, 13:270-276.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 270-276
    • Wellen, K.E.1    Thompson, C.B.2
  • 106
    • 33747603712 scopus 로고    scopus 로고
    • Sphingosine and ceramide signalling in apoptosis
    • Woodcock J. Sphingosine and ceramide signalling in apoptosis. IUBMB Life 2006, 58:462-466.
    • (2006) IUBMB Life , vol.58 , pp. 462-466
    • Woodcock, J.1
  • 112
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: opposing activities that mediate cell death
    • Youle R.J., Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008, 9:47-59.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 113
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J., Harada H., Yang E., Jockel J., Korsmeyer S.J. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 1996, 87:619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.