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Volumn 40, Issue 5, 2010, Pages 823-833

The Proapoptotic Function of Noxa in Human Leukemia Cells Is Regulated by the Kinase Cdk5 and by Glucose

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 5; GLUCOSE; PENTOSE PHOSPHATE; PROTEIN NOXA; SERINE;

EID: 78649973189     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.11.035     Document Type: Article
Times cited : (119)

References (42)
  • 1
  • 2
    • 33745006592 scopus 로고    scopus 로고
    • The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
    • Alves N.L., Derks I.A., Berk E., Spijker R., van Lier R.A., Eldering E. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 2006, 24:703-716.
    • (2006) Immunity , vol.24 , pp. 703-716
    • Alves, N.L.1    Derks, I.A.2    Berk, E.3    Spijker, R.4    van Lier, R.A.5    Eldering, E.6
  • 3
    • 33845636846 scopus 로고    scopus 로고
    • Withdrawal symptoms on display: Bcl-2 members under investigation
    • Alves N.L., van Lier R.A., Eldering E. Withdrawal symptoms on display: Bcl-2 members under investigation. Trends Immunol. 2007, 28:26-32.
    • (2007) Trends Immunol. , vol.28 , pp. 26-32
    • Alves, N.L.1    van Lier, R.A.2    Eldering, E.3
  • 5
    • 0033579464 scopus 로고    scopus 로고
    • Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
    • Blom N., Gammeltoft S., Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 1999, 294:1351-1362.
    • (1999) J. Mol. Biol. , vol.294 , pp. 1351-1362
    • Blom, N.1    Gammeltoft, S.2    Brunak, S.3
  • 9
    • 0033635235 scopus 로고    scopus 로고
    • 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
    • Datta S.R., Katsov A., Hu L., Petros A., Fesik S.W., Yaffe M.B., Greenberg M.E. 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol. Cell 2000, 6:41-51.
    • (2000) Mol. Cell , vol.6 , pp. 41-51
    • Datta, S.R.1    Katsov, A.2    Hu, L.3    Petros, A.4    Fesik, S.W.5    Yaffe, M.B.6    Greenberg, M.E.7
  • 11
    • 3242690522 scopus 로고    scopus 로고
    • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
    • Erster S., Mihara M., Kim R.H., Petrenko O., Moll U.M. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol. Cell. Biol. 2004, 24:6728-6741.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 6728-6741
    • Erster, S.1    Mihara, M.2    Kim, R.H.3    Petrenko, O.4    Moll, U.M.5
  • 12
    • 33845915536 scopus 로고    scopus 로고
    • Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5
    • Goodyear S., Sharma M.C. Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5. Exp. Mol. Pathol. 2007, 82:25-32.
    • (2007) Exp. Mol. Pathol. , vol.82 , pp. 25-32
    • Goodyear, S.1    Sharma, M.C.2
  • 14
    • 1542305653 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
    • Hershko T., Ginsberg D. Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J. Biol. Chem. 2004, 279:8627-8634.
    • (2004) J. Biol. Chem. , vol.279 , pp. 8627-8634
    • Hershko, T.1    Ginsberg, D.2
  • 15
    • 0025012137 scopus 로고
    • Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line
    • Hijikata M., Kato N., Sato T., Kagami Y., Shimotohno K. Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line. J. Virol. 1990, 64:4632-4639.
    • (1990) J. Virol. , vol.64 , pp. 4632-4639
    • Hijikata, M.1    Kato, N.2    Sato, T.3    Kagami, Y.4    Shimotohno, K.5
  • 16
    • 0346655211 scopus 로고    scopus 로고
    • BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
    • Kim J.Y., Ahn H.J., Ryu J.H., Suk K., Park J.H. BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha. J. Exp. Med. 2004, 199:113-124.
    • (2004) J. Exp. Med. , vol.199 , pp. 113-124
    • Kim, J.Y.1    Ahn, H.J.2    Ryu, J.H.3    Suk, K.4    Park, J.H.5
  • 17
    • 63149115282 scopus 로고    scopus 로고
    • The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes
    • Lalioti V., Muruais G., Dinarina A., van Damme J., Vandekerckhove J., Sandoval I.V. The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes. Proc. Natl. Acad. Sci. USA 2009, 106:4249-4253.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4249-4253
    • Lalioti, V.1    Muruais, G.2    Dinarina, A.3    van Damme, J.4    Vandekerckhove, J.5    Sandoval, I.V.6
  • 18
    • 0030823179 scopus 로고    scopus 로고
    • Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (beta HC9)
    • Liang Y., Buettger C., Berner D.K., Matschinsky F.M. Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (beta HC9). Diabetologia 1997, 40:1018-1027.
    • (1997) Diabetologia , vol.40 , pp. 1018-1027
    • Liang, Y.1    Buettger, C.2    Berner, D.K.3    Matschinsky, F.M.4
  • 19
    • 22344439156 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity
    • Luo S., Vacher C., Davies J.E., Rubinsztein D.C. Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity. J. Cell Biol. 2005, 169:647-656.
    • (2005) J. Cell Biol. , vol.169 , pp. 647-656
    • Luo, S.1    Vacher, C.2    Davies, J.E.3    Rubinsztein, D.C.4
  • 20
    • 33847353815 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose
    • Maher J.C., Wangpaichitr M., Savaraj N., Kurtoglu M., Lampidis T.J. Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose. Mol. Cancer Ther. 2007, 6:732-741.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 732-741
    • Maher, J.C.1    Wangpaichitr, M.2    Savaraj, N.3    Kurtoglu, M.4    Lampidis, T.J.5
  • 22
    • 33644855216 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
    • Maurer U., Charvet C., Wagman A.S., Dejardin E., Green D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol. Cell 2006, 21:749-760.
    • (2006) Mol. Cell , vol.21 , pp. 749-760
    • Maurer, U.1    Charvet, C.2    Wagman, A.S.3    Dejardin, E.4    Green, D.R.5
  • 23
    • 0025109484 scopus 로고
    • Glutaminolysis and glycolysis interactions in proliferant cells
    • Medina M.A., Nunez de Castro I. Glutaminolysis and glycolysis interactions in proliferant cells. Int. J. Biochem. 1990, 22:681-683.
    • (1990) Int. J. Biochem. , vol.22 , pp. 681-683
    • Medina, M.A.1    Nunez de Castro, I.2
  • 24
    • 65549155173 scopus 로고    scopus 로고
    • The Cdk5 inhibitor roscovitine strongly inhibits glucose uptake in 3T3-L1 adipocytes without altering GLUT4 translocation from internal pools to the cell surface
    • Muruais G., Lalioti V., Sandoval I.V. The Cdk5 inhibitor roscovitine strongly inhibits glucose uptake in 3T3-L1 adipocytes without altering GLUT4 translocation from internal pools to the cell surface. J. Cell. Physiol. 2009, 220:238-244.
    • (2009) J. Cell. Physiol. , vol.220 , pp. 238-244
    • Muruais, G.1    Lalioti, V.2    Sandoval, I.V.3
  • 27
  • 29
    • 30144442233 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
    • Perez-Galan P., Roue G., Villamor N., Montserrat E., Campo E., Colomer D. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood 2006, 107:257-264.
    • (2006) Blood , vol.107 , pp. 257-264
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Montserrat, E.4    Campo, E.5    Colomer, D.6
  • 30
    • 68149153007 scopus 로고    scopus 로고
    • Noxa: at the tip of the balance between life and death
    • Ploner C., Kofler R., Villunger A. Noxa: at the tip of the balance between life and death. Oncogene 2008, 27(Suppl 1):S84-S92.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Ploner, C.1    Kofler, R.2    Villunger, A.3
  • 31
    • 33750014263 scopus 로고    scopus 로고
    • Extraneuronal roles of cyclin-dependent kinase 5
    • Rosales J.L., Lee K.Y. Extraneuronal roles of cyclin-dependent kinase 5. Bioessays 2006, 28:1023-1034.
    • (2006) Bioessays , vol.28 , pp. 1023-1034
    • Rosales, J.L.1    Lee, K.Y.2
  • 33
    • 2542461194 scopus 로고    scopus 로고
    • Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells
    • Ubeda M., Kemp D.M., Habener J.F. Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells. Endocrinology 2004, 145:3023-3031.
    • (2004) Endocrinology , vol.145 , pp. 3023-3031
    • Ubeda, M.1    Kemp, D.M.2    Habener, J.F.3
  • 35
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 38
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 39
    • 42049091619 scopus 로고    scopus 로고
    • Unique biology of Mcl-1: therapeutic opportunities in cancer
    • Warr M.R., Shore G.C. Unique biology of Mcl-1: therapeutic opportunities in cancer. Curr. Mol. Med. 2008, 8:138-147.
    • (2008) Curr. Mol. Med. , vol.8 , pp. 138-147
    • Warr, M.R.1    Shore, G.C.2
  • 40
    • 22244464818 scopus 로고    scopus 로고
    • Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
    • Willis S.N., Chen L., Dewson G., Wei A., Naik E., Fletcher J.I., Adams J.M., Huang D.C. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev. 2005, 19:1294-1305.
    • (2005) Genes Dev. , vol.19 , pp. 1294-1305
    • Willis, S.N.1    Chen, L.2    Dewson, G.3    Wei, A.4    Naik, E.5    Fletcher, J.I.6    Adams, J.M.7    Huang, D.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.