-
1
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K., Kondo M., Freeden-Jeffry U., Murray R., and Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89 (1997) 1033-1041
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
2
-
-
0141705313
-
IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro
-
Alves N.L., Hooibrink B., Arosa F.A., and van Lier R.A. IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro. Blood 102 (2003) 2541-2546
-
(2003)
Blood
, vol.102
, pp. 2541-2546
-
-
Alves, N.L.1
Hooibrink, B.2
Arosa, F.A.3
van Lier, R.A.4
-
3
-
-
23244444668
-
IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells
-
Alves N.L., Arosa F.A., and van Lier R.A. IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. J. Immunol. 175 (2005) 755-762
-
(2005)
J. Immunol.
, vol.175
, pp. 755-762
-
-
Alves, N.L.1
Arosa, F.A.2
van Lier, R.A.3
-
4
-
-
18644367802
-
Cutting edge: CD95 maintains effector T cell homeostasis in chronic immune activation
-
Arens R., Baars P.A., Jak M., Tesselaar K., van der Valk M., van Oers M.H., and van Lier R.A. Cutting edge: CD95 maintains effector T cell homeostasis in chronic immune activation. J. Immunol. 174 (2005) 5915-5920
-
(2005)
J. Immunol.
, vol.174
, pp. 5915-5920
-
-
Arens, R.1
Baars, P.A.2
Jak, M.3
Tesselaar, K.4
van der Valk, M.5
van Oers, M.H.6
van Lier, R.A.7
-
5
-
-
0001646169
-
Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation
-
Boesen-de Cock J.G., Tepper A.D., de Vries E., van Blitterswijk W.J., and Borst J. Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation. J. Biol. Chem. 274 (1999) 14255-14261
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14255-14261
-
-
Boesen-de Cock, J.G.1
Tepper, A.D.2
de Vries, E.3
van Blitterswijk, W.J.4
Borst, J.5
-
6
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet P., Purton J.F., Godfrey D.I., Zhang L.C., Coultas L., Puthalakath H., Pellegrini M., Cory S., Adams J.M., and Strasser A. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415 (2002) 922-926
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
Purton, J.F.2
Godfrey, D.I.3
Zhang, L.C.4
Coultas, L.5
Puthalakath, H.6
Pellegrini, M.7
Cory, S.8
Adams, J.M.9
Strasser, A.10
-
7
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., and Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296 (2002) 550-553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
8
-
-
0035340150
-
Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL
-
Burr J.S., Savage N.D., Messah G.E., Kimzey S.L., Shaw A.S., Arch R.H., and Green J.M. Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL. J. Immunol. 166 (2001) 5331-5335
-
(2001)
J. Immunol.
, vol.166
, pp. 5331-5335
-
-
Burr, J.S.1
Savage, N.D.2
Messah, G.E.3
Kimzey, S.L.4
Shaw, A.S.5
Arch, R.H.6
Green, J.M.7
-
9
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L., Willis S.N., Wei A., Smith B.J., Fletcher J.I., Hinds M.G., Colman P.M., Day C.L., Adams J.M., and Huang D.C. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell 17 (2005) 393-403
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
10
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng E.H., Wei M.C., Weiler S., Flavell R.A., Mak T.W., Lindsten T., and Korsmeyer S.J. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8 (2001) 705-711
-
(2001)
Mol. Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
11
-
-
0842347424
-
Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death
-
Coultas L., Bouillet P., Stanley E.G., Brodnicki T.C., Adams J.M., and Strasser A. Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death. Mol. Cell. Biol. 24 (2004) 1570-1581
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1570-1581
-
-
Coultas, L.1
Bouillet, P.2
Stanley, E.G.3
Brodnicki, T.C.4
Adams, J.M.5
Strasser, A.6
-
12
-
-
0842281645
-
Cell death: critical control points
-
Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 (2004) 205-219
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
13
-
-
0028795758
-
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
-
Dhein J., Walczak H., Baumler C., Debatin K.M., and Krammer P.H. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373 (1995) 438-441
-
(1995)
Nature
, vol.373
, pp. 438-441
-
-
Dhein, J.1
Walczak, H.2
Baumler, C.3
Debatin, K.M.4
Krammer, P.H.5
-
14
-
-
84883843144
-
Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways
-
Eldering E., Spek C.A., Aberson H.L., Grummels A., Derks I.A., de Vos A.F., McElgunn C.J., and Schouten J.P. Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways. Nucleic Acids Res. 31 (2003) e153
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Eldering, E.1
Spek, C.A.2
Aberson, H.L.3
Grummels, A.4
Derks, I.A.5
de Vos, A.F.6
McElgunn, C.J.7
Schouten, J.P.8
-
15
-
-
28844472952
-
BH3-only proteins Puma and Bim are rate-limiting for {gamma}-radiation and glucocorticoid-induced apoptosis of lymphoid cells in vivo
-
Erlacher M., Michalak E.M., Kelly P.N., Labi V., Niederegger H., Coultas L., Adams J.M., Strasser A., and Villunger A. BH3-only proteins Puma and Bim are rate-limiting for {gamma}-radiation and glucocorticoid-induced apoptosis of lymphoid cells in vivo. Blood 106 (2005) 4131-4138
-
(2005)
Blood
, vol.106
, pp. 4131-4138
-
-
Erlacher, M.1
Michalak, E.M.2
Kelly, P.N.3
Labi, V.4
Niederegger, H.5
Coultas, L.6
Adams, J.M.7
Strasser, A.8
Villunger, A.9
-
16
-
-
14044251637
-
E1A activates transcription of p73 and Noxa to induce apoptosis
-
Flinterman M., Guelen L., Ezzati-Nik S., Killick R., Melino G., Tominaga K., Mymryk J.S., Gaken J., and Tavassoli M. E1A activates transcription of p73 and Noxa to induce apoptosis. J. Biol. Chem. 280 (2004) 5945-5959
-
(2004)
J. Biol. Chem.
, vol.280
, pp. 5945-5959
-
-
Flinterman, M.1
Guelen, L.2
Ezzati-Nik, S.3
Killick, R.4
Melino, G.5
Tominaga, K.6
Mymryk, J.S.7
Gaken, J.8
Tavassoli, M.9
-
17
-
-
1842581892
-
Regulation of T lymphocyte metabolism
-
Frauwirth K.A., and Thompson C.B. Regulation of T lymphocyte metabolism. J. Immunol. 172 (2004) 4661-4665
-
(2004)
J. Immunol.
, vol.172
, pp. 4661-4665
-
-
Frauwirth, K.A.1
Thompson, C.B.2
-
18
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth K.A., Riley J.L., Harris M.H., Parry R.V., Rathmell J.C., Plas D.R., Elstrom R.L., June C.H., and Thompson C.B. The CD28 signaling pathway regulates glucose metabolism. Immunity 16 (2002) 769-777
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
Parry, R.V.4
Rathmell, J.C.5
Plas, D.R.6
Elstrom, R.L.7
June, C.H.8
Thompson, C.B.9
-
19
-
-
10244237695
-
Monitoring the effect of gene silencing by RNA-interference in human CD34+ cells injected into newborn RAG2-/- gamma common-/- mice: functional inactivation of p53 in developing T cells
-
Gimeno R., Weijer K., Voordouw A., Uittenbogaart C.H., Legrand N., Alves N.L., Wijnands E., Blom B., and Spits H. Monitoring the effect of gene silencing by RNA-interference in human CD34+ cells injected into newborn RAG2-/- gamma common-/- mice: functional inactivation of p53 in developing T cells. Blood 104 (2004) 3886-3893
-
(2004)
Blood
, vol.104
, pp. 3886-3893
-
-
Gimeno, R.1
Weijer, K.2
Voordouw, A.3
Uittenbogaart, C.H.4
Legrand, N.5
Alves, N.L.6
Wijnands, E.7
Blom, B.8
Spits, H.9
-
20
-
-
15844422694
-
Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells
-
Gomez-Bougie P., Bataille R., and Amiot M. Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells. Eur. J. Immunol. 35 (2005) 971-976
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 971-976
-
-
Gomez-Bougie, P.1
Bataille, R.2
Amiot, M.3
-
21
-
-
0037769833
-
A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells
-
Gonzalez J., Orlofsky A., and Prystowsky M.B. A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells. Blood 101 (2003) 2679-2685
-
(2003)
Blood
, vol.101
, pp. 2679-2685
-
-
Gonzalez, J.1
Orlofsky, A.2
Prystowsky, M.B.3
-
22
-
-
0029974048
-
Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms
-
Hamann D., Baars P.A., Hooibrink B., and van Lier R.W. Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms. Blood 88 (1996) 3513-3521
-
(1996)
Blood
, vol.88
, pp. 3513-3521
-
-
Hamann, D.1
Baars, P.A.2
Hooibrink, B.3
van Lier, R.W.4
-
23
-
-
0036069819
-
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
-
Hildeman D.A., Zhu Y., Mitchell T.C., Bouillet P., Strasser A., Kappler J., and Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 16 (2002) 759-767
-
(2002)
Immunity
, vol.16
, pp. 759-767
-
-
Hildeman, D.A.1
Zhu, Y.2
Mitchell, T.C.3
Bouillet, P.4
Strasser, A.5
Kappler, J.6
Marrack, P.7
-
24
-
-
0035933115
-
T cell-specific FADD-deficient mice: FADD is required for early T cell development
-
Kabra N.H., Kang C., Hsing L.C., Zhang J., and Winoto A. T cell-specific FADD-deficient mice: FADD is required for early T cell development. Proc. Natl. Acad. Sci. USA 98 (2001) 6307-6312
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6307-6312
-
-
Kabra, N.H.1
Kang, C.2
Hsing, L.C.3
Zhang, J.4
Winoto, A.5
-
25
-
-
8844226681
-
CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack
-
Kater A.P., Evers L.M., Remmerswaal E.B., Jaspers A., Oosterwijk M.F., Lier R.A., Oers M.H., and Eldering E. CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack. Br. J. Haematol. 127 (2004) 404-415
-
(2004)
Br. J. Haematol.
, vol.127
, pp. 404-415
-
-
Kater, A.P.1
Evers, L.M.2
Remmerswaal, E.B.3
Jaspers, A.4
Oosterwijk, M.F.5
Lier, R.A.6
Oers, M.H.7
Eldering, E.8
-
26
-
-
1642444653
-
Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells
-
Kerstan A., and Hunig T. Cutting edge: distinct TCR- and CD28-derived signals regulate CD95L, Bcl-xL, and the survival of primary T cells. J. Immunol. 172 (2004) 1341-1345
-
(2004)
J. Immunol.
, vol.172
, pp. 1341-1345
-
-
Kerstan, A.1
Hunig, T.2
-
27
-
-
0346655211
-
BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1{alpha}
-
Kim J.Y., Ahn H.J., Ryu J.H., Suk K., and Park J.H. BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1{alpha}. J. Exp. Med. 199 (2004) 113-124
-
(2004)
J. Exp. Med.
, vol.199
, pp. 113-124
-
-
Kim, J.Y.1
Ahn, H.J.2
Ryu, J.H.3
Suk, K.4
Park, J.H.5
-
28
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T., Bouchier-Hayes L., Chipuk J.E., Bonzon C., Sullivan B.A., Green D.R., and Newmeyer D.D. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol. Cell 17 (2005) 525-535
-
(2005)
Mol. Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
Newmeyer, D.D.7
-
29
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A., Bassik M.C., Walensky L.D., Sorcinelli M.D., Weiler S., and Korsmeyer S.J. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2 (2002) 183-192
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
30
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
Li F., Ambrosini G., Chu E.Y., Plescia J., Tognin S., Marchisio P.C., and Altieri D.C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396 (1998) 580-584
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
Ambrosini, G.2
Chu, E.Y.3
Plescia, J.4
Tognin, S.5
Marchisio, P.C.6
Altieri, D.C.7
-
31
-
-
20144373877
-
Chronic lymphocytic leukemia cells display p53-dependent drug-induced Puma upregulation
-
Mackus W.J., Kater A.P., Grummels A., Evers L.M., Hooijbrink B., Kramer M.H., Castro J.E., Kipps T.J., van Lier R.A., van Oers M.H., and Eldering E. Chronic lymphocytic leukemia cells display p53-dependent drug-induced Puma upregulation. Leukemia 19 (2005) 427-434
-
(2005)
Leukemia
, vol.19
, pp. 427-434
-
-
Mackus, W.J.1
Kater, A.P.2
Grummels, A.3
Evers, L.M.4
Hooijbrink, B.5
Kramer, M.H.6
Castro, J.E.7
Kipps, T.J.8
van Lier, R.A.9
van Oers, M.H.10
Eldering, E.11
-
33
-
-
0038021272
-
Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more
-
Marsden V.S., and Strasser A. Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Annu. Rev. Immunol. 21 (2003) 71-105
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 71-105
-
-
Marsden, V.S.1
Strasser, A.2
-
34
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema J.P., Scaffidi C., Kischkel F.C., Shevchenko A., Mann M., Krammer P.H., and Peter M.E. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16 (1997) 2794-2804
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
35
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K., and Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7 (2001) 683-694
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
36
-
-
20144388905
-
Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis
-
Nencioni A., Hua F., Dillon C.P., Yokoo R., Scheiermann C., Cardone M.H., Barbieri E., Rocco I., Garuti A., Wesselborg S., et al. Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis. Blood 105 (2005) 3255-3262
-
(2005)
Blood
, vol.105
, pp. 3255-3262
-
-
Nencioni, A.1
Hua, F.2
Dillon, C.P.3
Yokoo, R.4
Scheiermann, C.5
Cardone, M.H.6
Barbieri, E.7
Rocco, I.8
Garuti, A.9
Wesselborg, S.10
-
37
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., Yamashita T., Tokino T., Taniguchi T., and Tanaka N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288 (2000) 1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
38
-
-
0348148880
-
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
-
Opferman J.T., Letai A., Beard C., Sorcinelli M.D., Ong C.C., and Korsmeyer S.J. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 426 (2003) 671-676
-
(2003)
Nature
, vol.426
, pp. 671-676
-
-
Opferman, J.T.1
Letai, A.2
Beard, C.3
Sorcinelli, M.D.4
Ong, C.C.5
Korsmeyer, S.J.6
-
39
-
-
0344198588
-
Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
-
Pellegrini M., Belz G., Bouillet P., and Strasser A. Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc. Natl. Acad. Sci. USA 100 (2003) 14175-14180
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14175-14180
-
-
Pellegrini, M.1
Belz, G.2
Bouillet, P.3
Strasser, A.4
-
40
-
-
0036078369
-
Homeostatic control of lymphocyte survival: potential origins and implications
-
Plas D.R., Rathmell J.C., and Thompson C.B. Homeostatic control of lymphocyte survival: potential origins and implications. Nat. Immunol. 3 (2002) 515-521
-
(2002)
Nat. Immunol.
, vol.3
, pp. 515-521
-
-
Plas, D.R.1
Rathmell, J.C.2
Thompson, C.B.3
-
41
-
-
0036097786
-
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H., and Strasser A. Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ. 9 (2002) 505-512
-
(2002)
Cell Death Differ.
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
42
-
-
4444303958
-
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
-
Qin J.Z., Stennett L., Bacon P., Bodner B., Hendrix M.J., Seftor R.E., Seftor E.A., Margaryan N.V., Pollock P.M., Curtis A., et al. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol. Cancer Ther. 3 (2004) 895-902
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 895-902
-
-
Qin, J.Z.1
Stennett, L.2
Bacon, P.3
Bodner, B.4
Hendrix, M.J.5
Seftor, R.E.6
Seftor, E.A.7
Margaryan, N.V.8
Pollock, P.M.9
Curtis, A.10
-
43
-
-
0033635249
-
In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability
-
Rathmell J.C., Vander Heiden M.G., Harris M.H., Frauwirth K.A., and Thompson C.B. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Mol. Cell 6 (2000) 683-692
-
(2000)
Mol. Cell
, vol.6
, pp. 683-692
-
-
Rathmell, J.C.1
Vander Heiden, M.G.2
Harris, M.H.3
Frauwirth, K.A.4
Thompson, C.B.5
-
44
-
-
0036794390
-
Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis
-
Rathmell J.C., Lindsten T., Zong W.X., Cinalli R.M., and Thompson C.B. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nat. Immunol. 3 (2002) 932-939
-
(2002)
Nat. Immunol.
, vol.3
, pp. 932-939
-
-
Rathmell, J.C.1
Lindsten, T.2
Zong, W.X.3
Cinalli, R.M.4
Thompson, C.B.5
-
45
-
-
1542327683
-
Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering
-
Sandalova E., Wei C.H., Masucci M.G., and Levitsky V. Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering. Proc. Natl. Acad. Sci. USA 101 (2004) 3011-3016
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3011-3016
-
-
Sandalova, E.1
Wei, C.H.2
Masucci, M.G.3
Levitsky, V.4
-
46
-
-
10744225736
-
The molecular mechanism of Noxa-induced mitochondrial dysfunction in p53-mediated cell death
-
Seo Y.W., Shin J.N., Ko K.H., Cha J.H., Park J.Y., Lee B.R., Yun C.W., Kim Y.M., Seol D.W., Kim D.W., et al. The molecular mechanism of Noxa-induced mitochondrial dysfunction in p53-mediated cell death. J. Biol. Chem. 278 (2003) 48292-48299
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48292-48299
-
-
Seo, Y.W.1
Shin, J.N.2
Ko, K.H.3
Cha, J.H.4
Park, J.Y.5
Lee, B.R.6
Yun, C.W.7
Kim, Y.M.8
Seol, D.W.9
Kim, D.W.10
-
47
-
-
0033811659
-
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
-
Shan X., Czar M.J., Bunnell S.C., Liu P., Liu Y., Schwartzberg P.L., and Wange R.L. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol. Cell. Biol. 20 (2000) 6945-6957
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6945-6957
-
-
Shan, X.1
Czar, M.J.2
Bunnell, S.C.3
Liu, P.4
Liu, Y.5
Schwartzberg, P.L.6
Wange, R.L.7
-
48
-
-
0141818136
-
Integral role of Noxa in p53-mediated apoptotic response
-
Shibue T., Takeda K., Oda E., Tanaka H., Murasawa H., Takaoka A., Morishita Y., Akira S., Taniguchi T., and Tanaka N. Integral role of Noxa in p53-mediated apoptotic response. Genes Dev. 17 (2003) 2233-2238
-
(2003)
Genes Dev.
, vol.17
, pp. 2233-2238
-
-
Shibue, T.1
Takeda, K.2
Oda, E.3
Tanaka, H.4
Murasawa, H.5
Takaoka, A.6
Morishita, Y.7
Akira, S.8
Taniguchi, T.9
Tanaka, N.10
-
49
-
-
14944348965
-
The role of BH3-only proteins in the immune system
-
Strasser A. The role of BH3-only proteins in the immune system. Nat. Rev. Immunol. 5 (2005) 189-200
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 189-200
-
-
Strasser, A.1
-
50
-
-
0025833603
-
T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways
-
van Lier R.A., Brouwer M., De Groot E.D., Kramer I., Aarden L.A., and Verhoeven A.J. T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways. Eur. J. Immunol. 21 (1991) 1775-1778
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 1775-1778
-
-
van Lier, R.A.1
Brouwer, M.2
De Groot, E.D.3
Kramer, I.4
Aarden, L.A.5
Verhoeven, A.J.6
-
51
-
-
0032587982
-
Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
-
Vander Heiden M.G., Chandel N.S., Schumacker P.T., and Thompson C.B. Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Mol. Cell 3 (1999) 159-167
-
(1999)
Mol. Cell
, vol.3
, pp. 159-167
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Schumacker, P.T.3
Thompson, C.B.4
-
52
-
-
0034904776
-
Growth factors can influence cell growth and survival through effects on glucose metabolism
-
Vander Heiden M.G., Plas D.R., Rathmell J.C., Fox C.J., Harris M.H., and Thompson C.B. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol. Cell. Biol. 21 (2001) 5899-5912
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5899-5912
-
-
Vander Heiden, M.G.1
Plas, D.R.2
Rathmell, J.C.3
Fox, C.J.4
Harris, M.H.5
Thompson, C.B.6
-
53
-
-
0041912327
-
A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes
-
Verschelde C., Walzer T., Galia P., Biemont M.C., Quemeneur L., Revillard J.P., Marvel J., and Bonnefoy-Berard N. A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes. Cell Death Differ. 10 (2003) 1059-1067
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1059-1067
-
-
Verschelde, C.1
Walzer, T.2
Galia, P.3
Biemont, M.C.4
Quemeneur, L.5
Revillard, J.P.6
Marvel, J.7
Bonnefoy-Berard, N.8
-
54
-
-
0242410719
-
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A., Michalak E.M., Coultas L., Mullauer F., Bock G., Ausserlechner M.J., Adams J.M., and Strasser A. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302 (2003) 1036-1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
55
-
-
2342458871
-
Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling
-
Villunger A., Marsden V.S., Zhan Y., Erlacher M., Lew A.M., Bouillet P., Berzins S., Godfrey D.I., Heath W.R., and Strasser A. Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling. Proc. Natl. Acad. Sci. USA 101 (2004) 7052-7057
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7052-7057
-
-
Villunger, A.1
Marsden, V.S.2
Zhan, Y.3
Erlacher, M.4
Lew, A.M.5
Bouillet, P.6
Berzins, S.7
Godfrey, D.I.8
Heath, W.R.9
Strasser, A.10
-
56
-
-
0035957653
-
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., Roth K.A., MacGregor G.R., Thompson C.B., and Korsmeyer S.J. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292 (2001) 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
57
-
-
0037151030
-
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax
-
Werner A.B., de Vries E., Tait S.W., Bontjer I., and Borst J. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax. J. Biol. Chem. 277 (2002) 22781-22788
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22781-22788
-
-
Werner, A.B.1
de Vries, E.2
Tait, S.W.3
Bontjer, I.4
Borst, J.5
-
58
-
-
22244464818
-
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
-
Willis S.N., Chen L., Dewson G., Wei A., Naik E., Fletcher J.I., Adams J.M., and Huang D.C. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev. 19 (2005) 1294-1305
-
(2005)
Genes Dev.
, vol.19
, pp. 1294-1305
-
-
Willis, S.N.1
Chen, L.2
Dewson, G.3
Wei, A.4
Naik, E.5
Fletcher, J.I.6
Adams, J.M.7
Huang, D.C.8
-
59
-
-
3142652618
-
Bok and Noxa are essential mediators of p53-dependent apoptosis
-
Yakovlev A.G., Di Giovanni S., Wang G., Liu W., Stoica B., and Faden A.I. Bok and Noxa are essential mediators of p53-dependent apoptosis. J. Biol. Chem. 279 (2004) 28367-28374
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28367-28374
-
-
Yakovlev, A.G.1
Di Giovanni, S.2
Wang, G.3
Liu, W.4
Stoica, B.5
Faden, A.I.6
-
60
-
-
21244472965
-
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
-
Zhong Q., Gao W., Du F., and Wang X. Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121 (2005) 1085-1095
-
(2005)
Cell
, vol.121
, pp. 1085-1095
-
-
Zhong, Q.1
Gao, W.2
Du, F.3
Wang, X.4
-
61
-
-
2442656629
-
Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells
-
Zhu Y., Swanson B.J., Wang M., Hildeman D.A., Schaefer B.C., Liu X., Suzuki H., Mihara K., Kappler J., and Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc. Natl. Acad. Sci. USA 101 (2004) 7681-7686
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7681-7686
-
-
Zhu, Y.1
Swanson, B.J.2
Wang, M.3
Hildeman, D.A.4
Schaefer, B.C.5
Liu, X.6
Suzuki, H.7
Mihara, K.8
Kappler, J.9
Marrack, P.10
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