Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice

Neuropharmacology

Volumn 58, Issue 6, 2010, Pages 911-920

  Hou, Yan ^a,c   Aboukhatwa, Marwa A ^a   Lei, De Liang ^d,e   Manaye, Kebreten ^e   Khan, Ikhlas ^f   Luo, Yuan ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF MATERIA MEDICA   (China)

^d Central South University   (China)

^e HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Amyloid beta oligomers; Depression; Natural flavonoids; Neuroplasticity

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; KAEMPFEROL; POSTSYNAPTIC DENSITY PROTEIN 95; QUERCETIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; EMBRYO; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; COGNITION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOLS; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KAEMPFEROLS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEURONS; PHOSPHORYLATION; PRESENILIN-1; QUERCETIN; RECEPTORS, CELL SURFACE; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 77649336424     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2009.11.002     Document Type: Article

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