-
1
-
-
77950479742
-
" Divine stramonium": the rise and fall of smoking for asthma
-
Jackson M. " Divine stramonium": the rise and fall of smoking for asthma. Med Hist 2010, 54:171-194.
-
(2010)
Med Hist
, vol.54
, pp. 171-194
-
-
Jackson, M.1
-
2
-
-
4644366286
-
The role of anticholinergics in asthma and COPD
-
Birkhäuser Verlag, Basel, J. Zaagsma, H. Meurs, A.F. Roffel (Eds.)
-
Chapman K.R. The role of anticholinergics in asthma and COPD. Muscarinic receptors in airways diseases 2001, 203-219. Birkhäuser Verlag, Basel. J. Zaagsma, H. Meurs, A.F. Roffel (Eds.).
-
(2001)
Muscarinic receptors in airways diseases
, pp. 203-219
-
-
Chapman, K.R.1
-
6
-
-
43549118894
-
Angel's trumpet (Datura stramonium) poisoning and delirium in adolescents in Winnipeg, Manitoba: Summer 2006
-
Wiebe T.H., Sigurdson E.S., Katz L.Y. Angel's trumpet (Datura stramonium) poisoning and delirium in adolescents in Winnipeg, Manitoba: Summer 2006. Paediatr Child Health 2008, 13:193-196.
-
(2008)
Paediatr Child Health
, vol.13
, pp. 193-196
-
-
Wiebe, T.H.1
Sigurdson, E.S.2
Katz, L.Y.3
-
9
-
-
0022622755
-
COPD: a disease of reversible air-flow obstruction
-
Gross N.J. COPD: a disease of reversible air-flow obstruction. Am Rev Respir Dis 1986, 133:725-726.
-
(1986)
Am Rev Respir Dis
, vol.133
, pp. 725-726
-
-
Gross, N.J.1
-
10
-
-
0031865167
-
The effect of adding ipratropium bromide to salbutamol in the treatment of acute asthma: a pooled analysis of three trials
-
Lanes S.F., Garrett J.E., Wentworth C.E., Fitzgerald J.M., Karpel J.P. The effect of adding ipratropium bromide to salbutamol in the treatment of acute asthma: a pooled analysis of three trials. Chest 1998, 114:365-372.
-
(1998)
Chest
, vol.114
, pp. 365-372
-
-
Lanes, S.F.1
Garrett, J.E.2
Wentworth, C.E.3
Fitzgerald, J.M.4
Karpel, J.P.5
-
11
-
-
0032832108
-
A meta-analysis of the effects of ipratropium bromide in adults with acute asthma
-
Rodrigo G., Rodrigo C., Burschtin O. A meta-analysis of the effects of ipratropium bromide in adults with acute asthma. Am J Med 1999, 107:363-370.
-
(1999)
Am J Med
, vol.107
, pp. 363-370
-
-
Rodrigo, G.1
Rodrigo, C.2
Burschtin, O.3
-
12
-
-
24744466684
-
Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis
-
Rodrigo G.J., Castro-Rodriguez J.A. Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis. Thorax 2005, 60:740-746.
-
(2005)
Thorax
, vol.60
, pp. 740-746
-
-
Rodrigo, G.J.1
Castro-Rodriguez, J.A.2
-
13
-
-
11844265905
-
One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium
-
Anzueto A., Tashkin D., Menjoge S., Kesten S. One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium. Pulm Pharmacol Ther 2005, 18:75-81.
-
(2005)
Pulm Pharmacol Ther
, vol.18
, pp. 75-81
-
-
Anzueto, A.1
Tashkin, D.2
Menjoge, S.3
Kesten, S.4
-
14
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
Tashkin D.P., Celli B., Senn S., Burkhart D., Kesten S., Menjoge S., et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008, 359:1543-1554.
-
(2008)
N Engl J Med
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
Burkhart, D.4
Kesten, S.5
Menjoge, S.6
-
15
-
-
70349547108
-
Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial
-
Decramer M., Celli B., Kesten S., Lystig T., Mehra S., Tashkin D.P. Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial. Lancet 2009, 374:1171-1178.
-
(2009)
Lancet
, vol.374
, pp. 1171-1178
-
-
Decramer, M.1
Celli, B.2
Kesten, S.3
Lystig, T.4
Mehra, S.5
Tashkin, D.P.6
-
16
-
-
77957157119
-
COPD in young patients: a pre-specified analysis of the four-year trial of tiotropium (UPLIFT)
-
Morice A.H., Celli B., Kesten S., Lystig T., Tashkin D., Decramer M. COPD in young patients: a pre-specified analysis of the four-year trial of tiotropium (UPLIFT). Respir Med 2010, 104:1659-1667.
-
(2010)
Respir Med
, vol.104
, pp. 1659-1667
-
-
Morice, A.H.1
Celli, B.2
Kesten, S.3
Lystig, T.4
Tashkin, D.5
Decramer, M.6
-
17
-
-
71249094666
-
Alternative mechanisms for tiotropium
-
Bateman E.D., Rennard S., Barnes P.J., Dicpinigaitis P.V., Gosens R., Gross N.J., et al. Alternative mechanisms for tiotropium. Pulm Pharmacol Ther 2009, 22:533-542.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 533-542
-
-
Bateman, E.D.1
Rennard, S.2
Barnes, P.J.3
Dicpinigaitis, P.V.4
Gosens, R.5
Gross, N.J.6
-
18
-
-
33745218112
-
Muscarinic receptor signaling in the pathophysiology of asthma and COPD
-
Gosens R., Zaagsma J., Meurs H., Halayko A.J. Muscarinic receptor signaling in the pathophysiology of asthma and COPD. Respir Res 2006, 7:73.
-
(2006)
Respir Res
, vol.7
, pp. 73
-
-
Gosens, R.1
Zaagsma, J.2
Meurs, H.3
Halayko, A.J.4
-
19
-
-
84872826158
-
-
doi:10.1016/j.lfs.2012.02.021, Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD. Life Sci, .
-
Kistemaker LE, Oenema TA, Meurs H, Gosens R. Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD. Life Sci, doi:10.1016/j.lfs.2012.02.021.
-
-
-
Kistemaker, L.E.1
Oenema, T.A.2
Meurs, H.3
Gosens, R.4
-
20
-
-
49449094458
-
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
-
Wessler I., Kirkpatrick C.J. Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans. Br J Pharmacol 2008, 154:1558-1571.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1558-1571
-
-
Wessler, I.1
Kirkpatrick, C.J.2
-
21
-
-
33646736505
-
Airway smooth muscle phenotype and function: interactions with current asthma therapies
-
Halayko A.J., Tran T., Ji S.Y., Yamasaki A., Gosens R. Airway smooth muscle phenotype and function: interactions with current asthma therapies. Curr Drug Targets 2006, 7:525-540.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 525-540
-
-
Halayko, A.J.1
Tran, T.2
Ji, S.Y.3
Yamasaki, A.4
Gosens, R.5
-
22
-
-
74849084373
-
Airway structural components drive airway smooth muscle remodeling in asthma
-
Dekkers B.G.J., Maarsingh H., Meurs H., Gosens R. Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc 2009, 6:683-692.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 683-692
-
-
Dekkers, B.G.J.1
Maarsingh, H.2
Meurs, H.3
Gosens, R.4
-
23
-
-
56149111462
-
Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models
-
Meurs H., Gosens R., Zaagsma J. Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models. Eur Respir J 2008, 32:487-502.
-
(2008)
Eur Respir J
, vol.32
, pp. 487-502
-
-
Meurs, H.1
Gosens, R.2
Zaagsma, J.3
-
24
-
-
33745855449
-
Remodeling in asthma and chronic obstructive pulmonary disease
-
Postma D.S., Timens W. Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006, 3:434-439.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 434-439
-
-
Postma, D.S.1
Timens, W.2
-
26
-
-
33845397124
-
Muscarinic receptors mediate stimulation of human lung fibroblast proliferation
-
Matthiesen S., Bahulayan A., Kempkens S., Haag S., Fuhrmann M., Stichnote C., et al. Muscarinic receptors mediate stimulation of human lung fibroblast proliferation. Am J Respir Cell Mol Biol 2006, 35:621-627.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 621-627
-
-
Matthiesen, S.1
Bahulayan, A.2
Kempkens, S.3
Haag, S.4
Fuhrmann, M.5
Stichnote, C.6
-
27
-
-
58149376396
-
Muscarinic receptors mediate stimulation of collagen synthesis in human lung fibroblasts
-
Haag S., Matthiesen S., Juergens U.R., Racké K. Muscarinic receptors mediate stimulation of collagen synthesis in human lung fibroblasts. Eur Respir J 2008, 32:555-562.
-
(2008)
Eur Respir J
, vol.32
, pp. 555-562
-
-
Haag, S.1
Matthiesen, S.2
Juergens, U.R.3
Racké, K.4
-
28
-
-
33748475192
-
Reflex regulation of airway smooth muscle tone
-
Canning B.J. Reflex regulation of airway smooth muscle tone. J Appl Physiol 2006, 101:971-985.
-
(2006)
J Appl Physiol
, vol.101
, pp. 971-985
-
-
Canning, B.J.1
-
29
-
-
0000140760
-
über die Wirkung der Bronchialmuskeln, nach einer neuen Methode untersucht, und über Asthma nervosum
-
Einthoven W. über die Wirkung der Bronchialmuskeln, nach einer neuen Methode untersucht, und über Asthma nervosum. Pflügers Arch 1892, 51:367-444.
-
(1892)
Pflügers Arch
, vol.51
, pp. 367-444
-
-
Einthoven, W.1
-
30
-
-
0030898519
-
Muscarinic control of airway function
-
Zaagsma J., Roffel A.F., Meurs H. Muscarinic control of airway function. Life Sci 1997, 60:1061-1068.
-
(1997)
Life Sci
, vol.60
, pp. 1061-1068
-
-
Zaagsma, J.1
Roffel, A.F.2
Meurs, H.3
-
31
-
-
3042525451
-
The airway cholinergic system: physiology and pharmacology
-
Racké K., Matthiesen S. The airway cholinergic system: physiology and pharmacology. Pulm Pharmacol Ther 2004, 17:181-198.
-
(2004)
Pulm Pharmacol Ther
, vol.17
, pp. 181-198
-
-
Racké, K.1
Matthiesen, S.2
-
32
-
-
28244483892
-
The role of vagal afferent nerves in chronic obstructive pulmonary disease
-
Undem B.J., Kollarik M. The role of vagal afferent nerves in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005, 2:355-360.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 355-360
-
-
Undem, B.J.1
Kollarik, M.2
-
33
-
-
0035722962
-
Pharmacology of airway afferent nerve activity
-
Undem B.J., Carr M.J. Pharmacology of airway afferent nerve activity. Respir Res 2001, 2:234-244.
-
(2001)
Respir Res
, vol.2
, pp. 234-244
-
-
Undem, B.J.1
Carr, M.J.2
-
34
-
-
0035123796
-
Transmission in autonomic ganglia
-
Myers A.C. Transmission in autonomic ganglia. Respir Physiol 2001, 125:99-111.
-
(2001)
Respir Physiol
, vol.125
, pp. 99-111
-
-
Myers, A.C.1
-
35
-
-
0023937461
-
The eosinophil as a mediator of damage to respiratory epithelium: a model for bronchial hyperreactivity
-
Gleich G.J., Flavahan N.A., Fujisawa T., Vanhoutte P.M. The eosinophil as a mediator of damage to respiratory epithelium: a model for bronchial hyperreactivity. J Allergy Clin Immunol 1988, 81:776-781.
-
(1988)
J Allergy Clin Immunol
, vol.81
, pp. 776-781
-
-
Gleich, G.J.1
Flavahan, N.A.2
Fujisawa, T.3
Vanhoutte, P.M.4
-
36
-
-
27644530096
-
Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease
-
Belmonte K.E. Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005, 2:297-304.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 297-304
-
-
Belmonte, K.E.1
-
39
-
-
65549128183
-
2 muscarinic receptors in antigen-challenged guinea pigs
-
2 muscarinic receptors in antigen-challenged guinea pigs. Br J Pharmacol 2009, 156:201-210.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 201-210
-
-
Nie, Z.1
Jacoby, D.B.2
Fryer, A.D.3
-
40
-
-
0024850599
-
A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects
-
Minette P.A., Lammers J.W., Dixon C.M., McCusker M.T., Barnes P.J. A muscarinic agonist inhibits reflex bronchoconstriction in normal but not in asthmatic subjects. J Appl Physiol 1989, 67:2461-2465.
-
(1989)
J Appl Physiol
, vol.67
, pp. 2461-2465
-
-
Minette, P.A.1
Lammers, J.W.2
Dixon, C.M.3
McCusker, M.T.4
Barnes, P.J.5
-
42
-
-
0015357904
-
Inhibition of antigen-induced bronchoconstriction by atropine in asthmatic patients
-
Yu D.Y., Galant S.P., Gold W.M. Inhibition of antigen-induced bronchoconstriction by atropine in asthmatic patients. J Appl Physiol 1972, 32:823-828.
-
(1972)
J Appl Physiol
, vol.32
, pp. 823-828
-
-
Yu, D.Y.1
Galant, S.P.2
Gold, W.M.3
-
43
-
-
0017602463
-
The effect of atropine on acute antigen-mediated airway constriction in subjects with allergic asthma
-
Fish J.E., Rosenthal R.R., Summer W.R., Menkes H., Norman P.S., Permutt S. The effect of atropine on acute antigen-mediated airway constriction in subjects with allergic asthma. Am Rev Respir Dis 1977, 115:371-379.
-
(1977)
Am Rev Respir Dis
, vol.115
, pp. 371-379
-
-
Fish, J.E.1
Rosenthal, R.R.2
Summer, W.R.3
Menkes, H.4
Norman, P.S.5
Permutt, S.6
-
45
-
-
84857089767
-
Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma
-
Buels K.S., Jacoby D.B., Fryer A.D. Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma. Br J Pharmacol 2012, 165:1501-1514.
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1501-1514
-
-
Buels, K.S.1
Jacoby, D.B.2
Fryer, A.D.3
-
46
-
-
84855204361
-
A role for sensory nerves in the late asthmatic response
-
Raemdonck K., de A.J., Birrell M.A., Grace M., Maher S.A., Irvin C.G., et al. A role for sensory nerves in the late asthmatic response. Thorax 2012, 67:19-25.
-
(2012)
Thorax
, vol.67
, pp. 19-25
-
-
Raemdonck, K.1
de, A.J.2
Birrell, M.A.3
Grace, M.4
Maher, S.A.5
Irvin, C.G.6
-
47
-
-
0010674611
-
Acetylcholine, a new active principle of Ergot
-
Ewins A.J. Acetylcholine, a new active principle of Ergot. Biochem J 1914, 8:44-49.
-
(1914)
Biochem J
, vol.8
, pp. 44-49
-
-
Ewins, A.J.1
-
48
-
-
0002845696
-
The presence of histamine and acetylcholine in the spleen of the ox and the horse
-
Dale H.H., Dudley H.W. The presence of histamine and acetylcholine in the spleen of the ox and the horse. J Physiol 1929, 68:97-123.
-
(1929)
J Physiol
, vol.68
, pp. 97-123
-
-
Dale, H.H.1
Dudley, H.W.2
-
49
-
-
0018239287
-
Cholinergic systems in non-nervous tissues
-
Sastry B.V., Sadavongvivad C. Cholinergic systems in non-nervous tissues. Pharmacol Rev 1978, 30:65-132.
-
(1978)
Pharmacol Rev
, vol.30
, pp. 65-132
-
-
Sastry, B.V.1
Sadavongvivad, C.2
-
50
-
-
0033033206
-
The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans
-
Wessler I., Kirkpatrick C.J., Racké K. The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans. Clin Exp Pharmacol Physiol 1999, 26:198-205.
-
(1999)
Clin Exp Pharmacol Physiol
, vol.26
, pp. 198-205
-
-
Wessler, I.1
Kirkpatrick, C.J.2
Racké, K.3
-
51
-
-
0029898794
-
Acetylcholine in isolated airways of rat, guinea pig, and human: species differences in role of airway mucosa
-
Reinheimer T., Bernedo P., Klapproth H., Oelert H., Zeiske B., Racké K., et al. Acetylcholine in isolated airways of rat, guinea pig, and human: species differences in role of airway mucosa. Am J Physiol 1996, 270:L722-L728.
-
(1996)
Am J Physiol
, vol.270
-
-
Reinheimer, T.1
Bernedo, P.2
Klapproth, H.3
Oelert, H.4
Zeiske, B.5
Racké, K.6
-
52
-
-
8044224009
-
Non-neuronal acetylcholine, a signalling molecule synthezised by surface cells of rat and man
-
Klapproth H., Reinheimer T., Metzen J., Munch M., Bittinger F., Kirkpatrick C.J., et al. Non-neuronal acetylcholine, a signalling molecule synthezised by surface cells of rat and man. Naunyn Schmiedebergs Arch Pharmacol 1997, 355:515-523.
-
(1997)
Naunyn Schmiedebergs Arch Pharmacol
, vol.355
, pp. 515-523
-
-
Klapproth, H.1
Reinheimer, T.2
Metzen, J.3
Munch, M.4
Bittinger, F.5
Kirkpatrick, C.J.6
-
53
-
-
2042443069
-
Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells
-
Proskocil B.J., Sekhon H.S., Jia Y., Savchenko V., Blakely R.D., Lindstrom J., et al. Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. Endocrinology 2004, 145:2498-2506.
-
(2004)
Endocrinology
, vol.145
, pp. 2498-2506
-
-
Proskocil, B.J.1
Sekhon, H.S.2
Jia, Y.3
Savchenko, V.4
Blakely, R.D.5
Lindstrom, J.6
-
54
-
-
48749124897
-
The epithelial cholinergic system of the airways
-
Kummer W., Lips K.S., Pfeil U. The epithelial cholinergic system of the airways. Histochem Cell Biol 2008, 130:219-234.
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 219-234
-
-
Kummer, W.1
Lips, K.S.2
Pfeil, U.3
-
55
-
-
21844457187
-
Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium
-
Lips K.S., Volk C., Schmitt B.M., Pfeil U., Arndt P., Miska D., et al. Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. Am J Respir Cell Mol Biol 2005, 33:79-88.
-
(2005)
Am J Respir Cell Mol Biol
, vol.33
, pp. 79-88
-
-
Lips, K.S.1
Volk, C.2
Schmitt, B.M.3
Pfeil, U.4
Arndt, P.5
Miska, D.6
-
56
-
-
2342622638
-
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea
-
Moffatt J.D., Cocks T.M., Page C.P. Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea. Br J Pharmacol 2004, 141:1159-1166.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 1159-1166
-
-
Moffatt, J.D.1
Cocks, T.M.2
Page, C.P.3
-
57
-
-
33845920612
-
Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse
-
Kummer W., Wiegand S., Akinci S., Schinkel A.H., Wess J., Koepsell H., et al. Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse. J Mol Neurosci 2006, 30:67-68.
-
(2006)
J Mol Neurosci
, vol.30
, pp. 67-68
-
-
Kummer, W.1
Wiegand, S.2
Akinci, S.3
Schinkel, A.H.4
Wess, J.5
Koepsell, H.6
-
58
-
-
33646856174
-
Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse
-
Kummer W., Wiegand S., Akinci S., Wessler I., Schinkel A.H., Wess J., et al. Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse. Respir Res 2006, 7:65.
-
(2006)
Respir Res
, vol.7
, pp. 65
-
-
Kummer, W.1
Wiegand, S.2
Akinci, S.3
Wessler, I.4
Schinkel, A.H.5
Wess, J.6
-
59
-
-
3042621605
-
Identification, localization and function of muscarinic receptor subtypes in the airways
-
Birkhäuser Verlag, Basel, J. Zaagsma, H. Meurs, A.F. Roffel (Eds.)
-
Roffel A.F., Meurs H., Zaagsma J. Identification, localization and function of muscarinic receptor subtypes in the airways. Muscarinic receptors in airways diseases 2001, 63-85. Birkhäuser Verlag, Basel. J. Zaagsma, H. Meurs, A.F. Roffel (Eds.).
-
(2001)
Muscarinic receptors in airways diseases
, pp. 63-85
-
-
Roffel, A.F.1
Meurs, H.2
Zaagsma, J.3
-
61
-
-
0025191514
-
3 receptors mediate contraction of human central and peripheral airway smooth muscle
-
3 receptors mediate contraction of human central and peripheral airway smooth muscle. Pulm Pharmacol 1990, 3:47-51.
-
(1990)
Pulm Pharmacol
, vol.3
, pp. 47-51
-
-
Roffel, A.F.1
Elzinga, C.R.S.2
Zaagsma, J.3
-
63
-
-
0036087875
-
3-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea
-
3-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea. Am J Physiol Regul Integr Comp Physiol 2002, 282:R1443-R1449.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
-
-
Stengel, P.W.1
Yamada, M.2
Wess, J.3
Cohen, M.L.4
-
65
-
-
0022838616
-
Carbachol induces a rapid and sustained hydrolysis of polyphosphoinositide in bovine tracheal smooth muscle measurements of the mass of polyphosphoinositides, 1,2-diacylglycerol, and phosphatidic acid
-
Takuwa Y., Takuwa N., Rasmussen H. Carbachol induces a rapid and sustained hydrolysis of polyphosphoinositide in bovine tracheal smooth muscle measurements of the mass of polyphosphoinositides, 1,2-diacylglycerol, and phosphatidic acid. J Biol Chem 1986, 261:14670-14675.
-
(1986)
J Biol Chem
, vol.261
, pp. 14670-14675
-
-
Takuwa, Y.1
Takuwa, N.2
Rasmussen, H.3
-
66
-
-
0023806550
-
Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists
-
Meurs H., Roffel A.F., Postema J.B., Timmermans A., Elzinga C.R.S., Kauffman H.F., et al. Evidence for a direct relationship between phosphoinositide metabolism and airway smooth muscle contraction induced by muscarinic agonists. Eur J Pharmacol 1988, 156:271-274.
-
(1988)
Eur J Pharmacol
, vol.156
, pp. 271-274
-
-
Meurs, H.1
Roffel, A.F.2
Postema, J.B.3
Timmermans, A.4
Elzinga, C.R.S.5
Kauffman, H.F.6
-
67
-
-
0025239952
-
Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle
-
Roffel A.F., Meurs H., Elzinga C.R.S., Zaagsma J. Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle. Br J Pharmacol 1990, 99:293-296.
-
(1990)
Br J Pharmacol
, vol.99
, pp. 293-296
-
-
Roffel, A.F.1
Meurs, H.2
Elzinga, C.R.S.3
Zaagsma, J.4
-
68
-
-
0024390318
-
Muscarinic receptors in human airway smooth muscle are coupled to phosphoinositide metabolism
-
Meurs H., Timmermans A., Van Amsterdam R.G.M., Brouwer F., Kauffman H.F., Zaagsma J. Muscarinic receptors in human airway smooth muscle are coupled to phosphoinositide metabolism. Eur J Pharmacol 1989, 164:369-371.
-
(1989)
Eur J Pharmacol
, vol.164
, pp. 369-371
-
-
Meurs, H.1
Timmermans, A.2
Van Amsterdam, R.G.M.3
Brouwer, F.4
Kauffman, H.F.5
Zaagsma, J.6
-
69
-
-
0025999794
-
Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells
-
Yang C.M., Chou S.P., Sung T.C. Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells. Br J Pharmacol 1991, 104:613-618.
-
(1991)
Br J Pharmacol
, vol.104
, pp. 613-618
-
-
Yang, C.M.1
Chou, S.P.2
Sung, T.C.3
-
70
-
-
0022394572
-
A role for inositol 1,4,5-trisphosphate in the initiation of agonist-induced contractions of dog tracheal smooth muscle
-
Hashimoto T., Hirata M., Ito Y. A role for inositol 1,4,5-trisphosphate in the initiation of agonist-induced contractions of dog tracheal smooth muscle. Br J Pharmacol 1985, 86:191-199.
-
(1985)
Br J Pharmacol
, vol.86
, pp. 191-199
-
-
Hashimoto, T.1
Hirata, M.2
Ito, Y.3
-
72
-
-
0026058812
-
Myosin phosphorylation/dephosphorylation and regulation of airway smooth muscle contractility
-
De Lanerolle P., Paul R.J. Myosin phosphorylation/dephosphorylation and regulation of airway smooth muscle contractility. Am J Physiol 1991, 261:L1-14.
-
(1991)
Am J Physiol
, vol.261
-
-
De Lanerolle, P.1
Paul, R.J.2
-
73
-
-
45249093865
-
ORAI and store-operated calcium influx in human airway smooth muscle cells
-
Peel S.E., Liu B., Hall I.P. ORAI and store-operated calcium influx in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2008, 38:744-749.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 744-749
-
-
Peel, S.E.1
Liu, B.2
Hall, I.P.3
-
74
-
-
37849052794
-
Calcium signaling in airway smooth muscle
-
Jude J.A., Wylam M.E., Walseth T.F., Kannan M.S. Calcium signaling in airway smooth muscle. Proc Am Thorac Soc 2008, 5:15-22.
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 15-22
-
-
Jude, J.A.1
Wylam, M.E.2
Walseth, T.F.3
Kannan, M.S.4
-
75
-
-
78349241740
-
Functional role of canonical transient receptor potential 1 and canonical transient receptor potential 3 in normal and asthmatic airway smooth muscle cells
-
Xiao J.H., Zheng Y.M., Liao B., Wang Y.X. Functional role of canonical transient receptor potential 1 and canonical transient receptor potential 3 in normal and asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol 2010, 43:17-25.
-
(2010)
Am J Respir Cell Mol Biol
, vol.43
, pp. 17-25
-
-
Xiao, J.H.1
Zheng, Y.M.2
Liao, B.3
Wang, Y.X.4
-
76
-
-
56649103777
-
New developments in the signaling mechanisms of the store-operated calcium entry pathway
-
Potier M., Trebak M. New developments in the signaling mechanisms of the store-operated calcium entry pathway. Pflugers Arch 2008, 457:405-415.
-
(2008)
Pflugers Arch
, vol.457
, pp. 405-415
-
-
Potier, M.1
Trebak, M.2
-
77
-
-
33749985960
-
Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells
-
Dietrich A., Chubanov V., Kalwa H., Rost B.R., Gudermann T. Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells. Pharmacol Ther 2006, 112:744-760.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 744-760
-
-
Dietrich, A.1
Chubanov, V.2
Kalwa, H.3
Rost, B.R.4
Gudermann, T.5
-
78
-
-
14444273436
-
Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes
-
Higashida H., Yokoyama S., Hashii M., Taketo M., Higashida M., Takayasu T., et al. Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes. J Biol Chem 1997, 272:31272-31277.
-
(1997)
J Biol Chem
, vol.272
, pp. 31272-31277
-
-
Higashida, H.1
Yokoyama, S.2
Hashii, M.3
Taketo, M.4
Higashida, M.5
Takayasu, T.6
-
79
-
-
0037365770
-
Intracellular calcium signaling through the cADPR pathway is agonist specific in porcine airway smooth muscle
-
White T.A., Kannan M.S., Walseth T.F. Intracellular calcium signaling through the cADPR pathway is agonist specific in porcine airway smooth muscle. FASEB J 2003, 17:482-484.
-
(2003)
FASEB J
, vol.17
, pp. 482-484
-
-
White, T.A.1
Kannan, M.S.2
Walseth, T.F.3
-
80
-
-
17444412638
-
CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle
-
Deshpande D.A., White T.A., Dogan S., Walseth T.F., Panettieri R.A., Kannan M.S. CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2005, 288:L773-L788.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Deshpande, D.A.1
White, T.A.2
Dogan, S.3
Walseth, T.F.4
Panettieri, R.A.5
Kannan, M.S.6
-
82
-
-
0028798086
-
Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle
-
Rossetti M., Savineau J.P., Crevel H., Marthan R. Role of protein kinase C in nonsensitized and passively sensitized human isolated bronchial smooth muscle. Am J Physiol 1995, 268:L966-L971.
-
(1995)
Am J Physiol
, vol.268
-
-
Rossetti, M.1
Savineau, J.P.2
Crevel, H.3
Marthan, R.4
-
85
-
-
0141751697
-
2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase
-
2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 2003, 83:1325-1358.
-
(2003)
Physiol Rev
, vol.83
, pp. 1325-1358
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
86
-
-
33645537849
-
Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction
-
Schaafsma D., Boterman M., de Jong A.M., Hovens I., Penninks J.M., Nelemans S.A., et al. Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction. Br J Pharmacol 2006, 147:737-743.
-
(2006)
Br J Pharmacol
, vol.147
, pp. 737-743
-
-
Schaafsma, D.1
Boterman, M.2
de Jong, A.M.3
Hovens, I.4
Penninks, J.M.5
Nelemans, S.A.6
-
87
-
-
33646023979
-
Rho-kinase as a drug target for the treatment of airway hyperresponsiveness in asthma
-
Gosens R., Schaafsma D., Nelemans S.A., Halayko A.J. Rho-kinase as a drug target for the treatment of airway hyperresponsiveness in asthma. Mini Rev Med Chem 2006, 6:339-348.
-
(2006)
Mini Rev Med Chem
, vol.6
, pp. 339-348
-
-
Gosens, R.1
Schaafsma, D.2
Nelemans, S.A.3
Halayko, A.J.4
-
89
-
-
43049096072
-
Rho kinase inhibitors: a novel therapeutical intervention in asthma?
-
Schaafsma D., Gosens R., Zaagsma J., Halayko A.J., Meurs H. Rho kinase inhibitors: a novel therapeutical intervention in asthma?. Eur J Pharmacol 2008, 585:398-406.
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 398-406
-
-
Schaafsma, D.1
Gosens, R.2
Zaagsma, J.3
Halayko, A.J.4
Meurs, H.5
-
90
-
-
0036893225
-
Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects
-
Ma X., Cheng Z., Kong H., Wang Y., Unruh H., Stephens N.L., et al. Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects. Am J Physiol Lung Cell Mol Physiol 2002, 283:L1181-L1189.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Ma, X.1
Cheng, Z.2
Kong, H.3
Wang, Y.4
Unruh, H.5
Stephens, N.L.6
-
91
-
-
0023230905
-
In vitro responses of airways from an asthmatic patient
-
de Jongste J.C., Mons H., Bonta I.L., Kerrebijn K.F. In vitro responses of airways from an asthmatic patient. Eur J Respir Dis 1987, 71:23-29.
-
(1987)
Eur J Respir Dis
, vol.71
, pp. 23-29
-
-
de Jongste, J.C.1
Mons, H.2
Bonta, I.L.3
Kerrebijn, K.F.4
-
92
-
-
0343570030
-
Peripheral airway smooth muscle mechanics in obstructive airways disease
-
Opazo Saez A.M., Seow C.Y., Pare P.D. Peripheral airway smooth muscle mechanics in obstructive airways disease. Am J Respir Crit Care Med 2000, 161:910-917.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 910-917
-
-
Opazo Saez, A.M.1
Seow, C.Y.2
Pare, P.D.3
-
93
-
-
0025342014
-
Abnormalities in airway smooth muscle in fatal asthma
-
Bai T.R. Abnormalities in airway smooth muscle in fatal asthma. Am Rev Respir Dis 1990, 141:552-557.
-
(1990)
Am Rev Respir Dis
, vol.141
, pp. 552-557
-
-
Bai, T.R.1
-
94
-
-
0030005408
-
Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle
-
Hakonarson H., Herrick D.J., Serrano P.G., Grunstein M.M. Mechanism of cytokine-induced modulation of β-adrenoceptor responsiveness in airway smooth muscle. J Clin Invest 1996, 97:2593-2600.
-
(1996)
J Clin Invest
, vol.97
, pp. 2593-2600
-
-
Hakonarson, H.1
Herrick, D.J.2
Serrano, P.G.3
Grunstein, M.M.4
-
95
-
-
0032899404
-
qα protein expression and function in human airway smooth muscle cells
-
qα protein expression and function in human airway smooth muscle cells. Am J Physiol 1999, 276:L405-L411.
-
(1999)
Am J Physiol
, vol.276
-
-
Hotta, K.1
Emala, C.W.2
Hirshman, C.A.3
-
96
-
-
3042795833
-
Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway
-
Deshpande D.A., Dogan S., Walseth T.F., Miller S.M., Amrani Y., Panettieri R.A., et al. Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway. Am J Respir Cell Mol Biol 2004, 31:36-42.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 36-42
-
-
Deshpande, D.A.1
Dogan, S.2
Walseth, T.F.3
Miller, S.M.4
Amrani, Y.5
Panettieri, R.A.6
-
97
-
-
3342958754
-
Tumor necrosis factor-α differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-β-dependent CD38 pathway
-
Tliba O., Panettieri R.A., Tliba S., Walseth T.F., Amrani Y. Tumor necrosis factor-α differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-β-dependent CD38 pathway. Mol Pharmacol 2004, 66:322-329.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 322-329
-
-
Tliba, O.1
Panettieri, R.A.2
Tliba, S.3
Walseth, T.F.4
Amrani, Y.5
-
99
-
-
78649832047
-
Differential induction of CD38 expression by TNF-α in asthmatic airway smooth muscle cells
-
Jude J.A., Solway J., Panettieri R.A., Walseth T.F., Kannan M.S. Differential induction of CD38 expression by TNF-α in asthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2010, 299:L879-L890.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.299
-
-
Jude, J.A.1
Solway, J.2
Panettieri, R.A.3
Walseth, T.F.4
Kannan, M.S.5
-
100
-
-
33746790245
-
Role of transient receptor potential C3 in TNF-α-enhanced calcium influx in human airway myocytes
-
White T.A., Xue A., Chini E.N., Thompson M., Sieck G.C., Wylam M.E. Role of transient receptor potential C3 in TNF-α-enhanced calcium influx in human airway myocytes. Am J Respir Cell Mol Biol 2006, 35:243-251.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 243-251
-
-
White, T.A.1
Xue, A.2
Chini, E.N.3
Thompson, M.4
Sieck, G.C.5
Wylam, M.E.6
-
101
-
-
7544221330
-
Allergic sensitization enhances the contribution of Rho-kinase to airway smooth muscle contraction
-
Schaafsma D., Gosens R., Bos I.S.T., Meurs H., Zaagsma J., Nelemans S.A. Allergic sensitization enhances the contribution of Rho-kinase to airway smooth muscle contraction. Br J Pharmacol 2004, 143:477-484.
-
(2004)
Br J Pharmacol
, vol.143
, pp. 477-484
-
-
Schaafsma, D.1
Gosens, R.2
Bos, I.S.T.3
Meurs, H.4
Zaagsma, J.5
Nelemans, S.A.6
-
103
-
-
33749433631
-
Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction
-
Schaafsma D., Bos I.S.T., Zuidhof A.B., Zaagsma J., Meurs H. Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction. Respir Res 2006, 7:121.
-
(2006)
Respir Res
, vol.7
, pp. 121
-
-
Schaafsma, D.1
Bos, I.S.T.2
Zuidhof, A.B.3
Zaagsma, J.4
Meurs, H.5
-
104
-
-
32044464038
-
Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations
-
Schaafsma D., Zuidhof A.B., Nelemans S.A., Zaagsma J., Meurs H. Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations. Eur J Pharmacol 2006, 531:145-150.
-
(2006)
Eur J Pharmacol
, vol.531
, pp. 145-150
-
-
Schaafsma, D.1
Zuidhof, A.B.2
Nelemans, S.A.3
Zaagsma, J.4
Meurs, H.5
-
105
-
-
49049090820
-
The inhaled rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation
-
Schaafsma D., Bos I.S.T., Zuidhof A.B., Zaagsma J., Meurs H. The inhaled rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation. Am J Physiol Lung Cell Mol Physiol 2008, 295:L214-L219.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Schaafsma, D.1
Bos, I.S.T.2
Zuidhof, A.B.3
Zaagsma, J.4
Meurs, H.5
-
106
-
-
10644234866
-
A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophilia, bronchoconstriction and airways hyperresponsiveness in allergic mice
-
Henry P.J., Mann T.S., Goldie R.G. A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophilia, bronchoconstriction and airways hyperresponsiveness in allergic mice. Pulm Pharmacol Ther 2005, 18:67-74.
-
(2005)
Pulm Pharmacol Ther
, vol.18
, pp. 67-74
-
-
Henry, P.J.1
Mann, T.S.2
Goldie, R.G.3
-
107
-
-
78649424607
-
RhoA, a possible target for treatment of airway hyperresponsiveness in bronchial asthma
-
Chiba Y., Matsusue K., Misawa M. RhoA, a possible target for treatment of airway hyperresponsiveness in bronchial asthma. J Pharmacol Sci 2010, 114:239-247.
-
(2010)
J Pharmacol Sci
, vol.114
, pp. 239-247
-
-
Chiba, Y.1
Matsusue, K.2
Misawa, M.3
-
108
-
-
59149107299
-
Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein
-
Chiba Y., Nakazawa S., Todoroki M., Shinozaki K., Sakai H., Misawa M. Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein. Am J Respir Cell Mol Biol 2009, 40:159-167.
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, pp. 159-167
-
-
Chiba, Y.1
Nakazawa, S.2
Todoroki, M.3
Shinozaki, K.4
Sakai, H.5
Misawa, M.6
-
109
-
-
9344263478
-
Involvement of p42/44 MAPK and RhoA protein in augmentation of ACh-induced bronchial smooth muscle contraction by TNF-alpha in rats
-
Sakai H., Otogoto S., Chiba Y., Abe K., Misawa M. Involvement of p42/44 MAPK and RhoA protein in augmentation of ACh-induced bronchial smooth muscle contraction by TNF-alpha in rats. J Appl Physiol 2004, 97:2154-2159.
-
(2004)
J Appl Physiol
, vol.97
, pp. 2154-2159
-
-
Sakai, H.1
Otogoto, S.2
Chiba, Y.3
Abe, K.4
Misawa, M.5
-
110
-
-
77950629897
-
The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells
-
Goto K., Chiba Y., Matsusue K., Hattori Y., Maitani Y., Sakai H., et al. The proximal STAT6 and NF-κB sites are responsible for IL-13- and TNF-α-induced RhoA transcriptions in human bronchial smooth muscle cells. Pharmacol Res 2010, 61:466-472.
-
(2010)
Pharmacol Res
, vol.61
, pp. 466-472
-
-
Goto, K.1
Chiba, Y.2
Matsusue, K.3
Hattori, Y.4
Maitani, Y.5
Sakai, H.6
-
111
-
-
57349099404
-
CPI-17 silencing-reduced responsiveness in control and TNF-α-treated human bronchi
-
Morin C., Sirois M., Echave V., Rousseau E. CPI-17 silencing-reduced responsiveness in control and TNF-α-treated human bronchi. Am J Respir Cell Mol Biol 2008, 39:638-643.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 638-643
-
-
Morin, C.1
Sirois, M.2
Echave, V.3
Rousseau, E.4
-
112
-
-
22344455236
-
Possible involvement of CPI-17 in augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats
-
Sakai H., Chiba Y., Hirano T., Misawa M. Possible involvement of CPI-17 in augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats. Mol Pharmacol 2005, 68:145-151.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 145-151
-
-
Sakai, H.1
Chiba, Y.2
Hirano, T.3
Misawa, M.4
-
115
-
-
0035164457
-
Molecular mechanisms of phenotypic plasticity in smooth muscle cells
-
Halayko A.J., Solway J. Molecular mechanisms of phenotypic plasticity in smooth muscle cells. J Appl Physiol 2001, 90:358-368.
-
(2001)
J Appl Physiol
, vol.90
, pp. 358-368
-
-
Halayko, A.J.1
Solway, J.2
-
116
-
-
37849043647
-
Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins
-
Halayko A.J., Tran T., Gosens R. Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins. Proc Am Thorac Soc 2008, 5:80-88.
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 80-88
-
-
Halayko, A.J.1
Tran, T.2
Gosens, R.3
-
117
-
-
84873119537
-
Muscarinic receptor stimulation augments TGF-β1-induced contractile protein expression by airway smooth muscle cells
-
in press.
-
Oenema TA, Smit M, Smedinga L, Racké K, Halayko AJ, Meurs H, Gosens R. Muscarinic receptor stimulation augments TGF-β1-induced contractile protein expression by airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol, in press.
-
Am J Physiol Lung Cell Mol Physiol
-
-
Oenema, T.A.1
Smit, M.2
Smedinga, L.3
Racké, K.4
Halayko, A.J.5
Meurs, H.6
Gosens, R.7
-
118
-
-
32044449846
-
Transforming growth factor-β induces airway smooth muscle hypertrophy
-
Goldsmith A.M., Bentley J.K., Zhou L., Jia Y., Bitar K.N., Fingar D.C., et al. Transforming growth factor-β induces airway smooth muscle hypertrophy. Am J Respir Cell Mol Biol 2006, 34:247-254.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 247-254
-
-
Goldsmith, A.M.1
Bentley, J.K.2
Zhou, L.3
Jia, Y.4
Bitar, K.N.5
Fingar, D.C.6
-
119
-
-
0035143413
-
Triggering the induction of myofibroblast and fibrogenesis by airway epithelial shedding
-
Morishima Y., Nomura A., Uchida Y., Noguchi Y., Sakamoto T., Ishii Y., et al. Triggering the induction of myofibroblast and fibrogenesis by airway epithelial shedding. Am J Respir Cell Mol Biol 2001, 24:1-11.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 1-11
-
-
Morishima, Y.1
Nomura, A.2
Uchida, Y.3
Noguchi, Y.4
Sakamoto, T.5
Ishii, Y.6
-
120
-
-
33749256297
-
Endogenous laminin is required for human airway smooth muscle cell maturation
-
Tran T., McNeill K.D., Gerthoffer W.T., Unruh H., Halayko A.J. Endogenous laminin is required for human airway smooth muscle cell maturation. Respir Res 2006, 7:117.
-
(2006)
Respir Res
, vol.7
, pp. 117
-
-
Tran, T.1
McNeill, K.D.2
Gerthoffer, W.T.3
Unruh, H.4
Halayko, A.J.5
-
121
-
-
34447573660
-
Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function
-
Dekkers B.G.J., Schaafsma D., Nelemans S.A., Zaagsma J., Meurs H. Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function. Am J Physiol Lung Cell Mol Physiol 2007, 292:L1405-L1413.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Dekkers, B.G.J.1
Schaafsma, D.2
Nelemans, S.A.3
Zaagsma, J.4
Meurs, H.5
-
122
-
-
70349150537
-
Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype
-
Dekkers B.G.J., Schaafsma D., Tran T., Zaagsma J., Meurs H. Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype. Am J Respir Cell Mol Biol 2009, 41:494-504.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 494-504
-
-
Dekkers, B.G.J.1
Schaafsma, D.2
Tran, T.3
Zaagsma, J.4
Meurs, H.5
-
123
-
-
4444302962
-
Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation
-
Halayko A.J., Kartha S., Stelmack G.L., McConville J., Tam J., Camoretti-Mercado B., et al. Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation. Am J Respir Cell Mol Biol 2004, 31:266-275.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 266-275
-
-
Halayko, A.J.1
Kartha, S.2
Stelmack, G.L.3
McConville, J.4
Tam, J.5
Camoretti-Mercado, B.6
-
124
-
-
0012265697
-
The rhoA/rho kinase pathway regulates nuclear localization of serum response factor
-
Liu H.W., Halayko A.J., Fernandes D.J., Harmon G.S., McCauley J.A., Kocieniewski P., et al. The rhoA/rho kinase pathway regulates nuclear localization of serum response factor. Am J Respir Cell Mol Biol 2003, 29:39-47.
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
, pp. 39-47
-
-
Liu, H.W.1
Halayko, A.J.2
Fernandes, D.J.3
Harmon, G.S.4
McCauley, J.A.5
Kocieniewski, P.6
-
125
-
-
34547098368
-
Insulin increases the expression of contractile phenotypic markers in airway smooth muscle
-
Schaafsma D., McNeill K.D., Stelmack G.L., Gosens R., Baarsma H.A., Dekkers B.G.J., et al. Insulin increases the expression of contractile phenotypic markers in airway smooth muscle. Am J Physiol Cell Physiol 2007, 293:C429-C439.
-
(2007)
Am J Physiol Cell Physiol
, vol.293
-
-
Schaafsma, D.1
McNeill, K.D.2
Stelmack, G.L.3
Gosens, R.4
Baarsma, H.A.5
Dekkers, B.G.J.6
-
126
-
-
0346096592
-
Role of rho-kinase in maintaining airway smooth muscle contractile phenotype
-
Gosens R., Schaafsma D., Meurs H., Zaagsma J., Nelemans S.A. Role of rho-kinase in maintaining airway smooth muscle contractile phenotype. Eur J Pharmacol 2004, 483:71-78.
-
(2004)
Eur J Pharmacol
, vol.483
, pp. 71-78
-
-
Gosens, R.1
Schaafsma, D.2
Meurs, H.3
Zaagsma, J.4
Nelemans, S.A.5
-
127
-
-
0033787918
-
Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle
-
Krymskaya V.P., Orsini M.J., Eszterhas A.J., Brodbeck K.C., Benovic J.L., Panettieri R.A., et al. Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle. Am J Respir Cell Mol Biol 2000, 23:546-554.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 546-554
-
-
Krymskaya, V.P.1
Orsini, M.J.2
Eszterhas, A.J.3
Brodbeck, K.C.4
Benovic, J.L.5
Panettieri, R.A.6
-
128
-
-
59249095555
-
Caveolae and caveolins in the respiratory system
-
Gosens R., Mutawe M., Martin S., Basu S., Bos I.S.T., Tran T., et al. Caveolae and caveolins in the respiratory system. Curr Mol Med 2008, 8:741-753.
-
(2008)
Curr Mol Med
, vol.8
, pp. 741-753
-
-
Gosens, R.1
Mutawe, M.2
Martin, S.3
Basu, S.4
Bos, I.S.T.5
Tran, T.6
-
129
-
-
33748421657
-
Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle
-
Gosens R., Stelmack G.L., Dueck G., McNeill K.D., Yamasaki A., Gerthoffer W.T., et al. Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006, 291:L523-L534.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Gosens, R.1
Stelmack, G.L.2
Dueck, G.3
McNeill, K.D.4
Yamasaki, A.5
Gerthoffer, W.T.6
-
130
-
-
34447563588
-
P42/p44 MAP kinase activation is localized to caveolae-free membrane domains in airway smooth muscle
-
Gosens R., Dueck G., Gerthoffer W.T., Unruh H., Zaagsma J., Meurs H., et al. p42/p44 MAP kinase activation is localized to caveolae-free membrane domains in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2007, 292:L1163-L1172.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Gosens, R.1
Dueck, G.2
Gerthoffer, W.T.3
Unruh, H.4
Zaagsma, J.5
Meurs, H.6
-
131
-
-
36348971329
-
Caveolins and intracellular calcium regulation in human airway smooth muscle
-
Prakash Y.S., Thompson M.A., Vaa B., Matabdin I., Peterson T.E., He T., et al. Caveolins and intracellular calcium regulation in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2007, 293:L1118-L1126.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Prakash, Y.S.1
Thompson, M.A.2
Vaa, B.3
Matabdin, I.4
Peterson, T.E.5
He, T.6
-
133
-
-
77951553776
-
Muscarinic receptor-mediated bronchoconstriction is coupled to caveolae in murine airways
-
Schlenz H., Kummer W., Jositsch G., Wess J., Krasteva G. Muscarinic receptor-mediated bronchoconstriction is coupled to caveolae in murine airways. Am J Physiol Lung Cell Mol Physiol 2010, 298:L626-L636.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.298
-
-
Schlenz, H.1
Kummer, W.2
Jositsch, G.3
Wess, J.4
Krasteva, G.5
-
135
-
-
80054952112
-
Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells
-
Gosens R., Stelmack G.L., Bos S.T., Dueck G., Mutawe M.M., Schaafsma D., et al. Caveolin-1 is required for contractile phenotype expression by airway smooth muscle cells. J Cell Mol Med 2011, 15:2430-2442.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 2430-2442
-
-
Gosens, R.1
Stelmack, G.L.2
Bos, S.T.3
Dueck, G.4
Mutawe, M.M.5
Schaafsma, D.6
-
136
-
-
0023765728
-
Muscarinic cholinergic inhibition of cyclic AMP accumulation in airway smooth muscle. Role of a pertussis toxin-sensitive protein
-
Sankary R.M., Jones C.A., Madison J.M., Brown J.K. Muscarinic cholinergic inhibition of cyclic AMP accumulation in airway smooth muscle. Role of a pertussis toxin-sensitive protein. Am Rev Respir Dis 1988, 138:145-150.
-
(1988)
Am Rev Respir Dis
, vol.138
, pp. 145-150
-
-
Sankary, R.M.1
Jones, C.A.2
Madison, J.M.3
Brown, J.K.4
-
137
-
-
0026341903
-
Ca channels in smooth muscle cells by a pertussis-sensitive G protein
-
Ca channels in smooth muscle cells by a pertussis-sensitive G protein. Am J Physiol 1991, 261:C1204-C1209.
-
(1991)
Am J Physiol
, vol.261
-
-
Kume, H.1
Kotlikoff, M.I.2
-
139
-
-
0026612959
-
2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle
-
2 muscarinic receptors inhibit isoproterenol-induced relaxation of canine airway smooth muscle. J Pharmacol Exp Ther 1992, 262:119-126.
-
(1992)
J Pharmacol Exp Ther
, vol.262
, pp. 119-126
-
-
Fernandes, L.B.1
Fryer, A.D.2
Hirshman, C.A.3
-
140
-
-
0028178951
-
3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro
-
3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro. Br J Pharmacol 1994, 112:179-187.
-
(1994)
Br J Pharmacol
, vol.112
, pp. 179-187
-
-
Watson, N.1
Eglen, R.M.2
-
141
-
-
0027331407
-
2 receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle
-
2 receptors do not participate in the functional antagonism between methacholine and isoprenaline in guinea pig tracheal smooth muscle. Eur J Pharmacol 1993, 249:235-238.
-
(1993)
Eur J Pharmacol
, vol.249
, pp. 235-238
-
-
Roffel, A.F.1
Meurs, H.2
Elzinga, C.R.3
Zaagsma, J.4
-
143
-
-
0028985618
-
Antagonism of β-adrenoceptor-mediated relaxations of human bronchial smooth muscle by carbachol
-
Watson N., Magnussen H., Rabe K.F. Antagonism of β-adrenoceptor-mediated relaxations of human bronchial smooth muscle by carbachol. Eur J Pharmacol 1995, 275:307-310.
-
(1995)
Eur J Pharmacol
, vol.275
, pp. 307-310
-
-
Watson, N.1
Magnussen, H.2
Rabe, K.F.3
-
144
-
-
0025183653
-
Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by β-adrenoceptor agonists
-
Van Amsterdam R.G., Meurs H., Ten Berge R.E., Veninga N.C., Brouwer F., Zaagsma J. Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by β-adrenoceptor agonists. Am Rev Respir Dis 1990, 142:1124-1128.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 1124-1128
-
-
Van Amsterdam, R.G.1
Meurs, H.2
Ten Berge, R.E.3
Veninga, N.C.4
Brouwer, F.5
Zaagsma, J.6
-
146
-
-
84863121246
-
G protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma
-
Nino G., Hu A., Grunstein J.S., McDonough J., Kreiger P.A., Josephson M.B., et al. G protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma. PLoS One 2012, 7:e32078.
-
(2012)
PLoS One
, vol.7
-
-
Nino, G.1
Hu, A.2
Grunstein, J.S.3
McDonough, J.4
Kreiger, P.A.5
Josephson, M.B.6
-
147
-
-
0344412211
-
Muscarinic receptor-β-adrenoceptor cross-talk in airway smooth muscle
-
Birkhäuser Verlag, Basel, J. Zaagsma, H. Meurs, A.F. Roffel (Eds.)
-
Meurs H., Roffel A.F., Elzinga C.R.S., Zaagsma J. Muscarinic receptor-β-adrenoceptor cross-talk in airway smooth muscle. Muscarinic receptors in airways diseases 2001, 121-158. Birkhäuser Verlag, Basel. J. Zaagsma, H. Meurs, A.F. Roffel (Eds.).
-
(2001)
Muscarinic receptors in airways diseases
, pp. 121-158
-
-
Meurs, H.1
Roffel, A.F.2
Elzinga, C.R.S.3
Zaagsma, J.4
-
148
-
-
0024448805
-
Role of phosphoinositide metabolism in functional antagonism of airway smooth muscle contraction by β-adrenoceptor agonists
-
van Amsterdam R.G.M., Meurs H., Brouwer F., Postema J.B., Timmermans A., Zaagsma J. Role of phosphoinositide metabolism in functional antagonism of airway smooth muscle contraction by β-adrenoceptor agonists. Eur J Pharmacol 1989, 172:175-183.
-
(1989)
Eur J Pharmacol
, vol.172
, pp. 175-183
-
-
van Amsterdam, R.G.M.1
Meurs, H.2
Brouwer, F.3
Postema, J.B.4
Timmermans, A.5
Zaagsma, J.6
-
149
-
-
0028009707
-
Modulation of airway smooth muscle β-adrenoceptor function by a muscarinic agonist
-
Grandordy B.M., Mak J.C., Barnes P.J. Modulation of airway smooth muscle β-adrenoceptor function by a muscarinic agonist. Life Sci 1994, 54:185-191.
-
(1994)
Life Sci
, vol.54
, pp. 185-191
-
-
Grandordy, B.M.1
Mak, J.C.2
Barnes, P.J.3
-
150
-
-
20344402041
-
Potentiation of β-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C
-
Boterman M., Elzinga C.R.S., Wagemakers D., Eppens P.B., Zaagsma J., Meurs H. Potentiation of β-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C. Eur J Pharmacol 2005, 516:85-92.
-
(2005)
Eur J Pharmacol
, vol.516
, pp. 85-92
-
-
Boterman, M.1
Elzinga, C.R.S.2
Wagemakers, D.3
Eppens, P.B.4
Zaagsma, J.5
Meurs, H.6
-
151
-
-
0022374275
-
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
-
Sibley D.R., Lefkowitz R.J. Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model. Nature 1985, 317:124-129.
-
(1985)
Nature
, vol.317
, pp. 124-129
-
-
Sibley, D.R.1
Lefkowitz, R.J.2
-
152
-
-
0026068576
-
'Crosstalk': a pivotal role for protein kinase C in modulating relationships between signal transduction pathways
-
Houslay M.D. 'Crosstalk': a pivotal role for protein kinase C in modulating relationships between signal transduction pathways. Eur J Biochem 1991, 195:9-27.
-
(1991)
Eur J Biochem
, vol.195
, pp. 9-27
-
-
Houslay, M.D.1
-
153
-
-
0026697132
-
Phosphorylation of the spliced variant forms of the recombinant stimulatory guanine-nucleotide-binding regulatory protein (Gs alpha) by protein kinase C
-
Pyne N.J., Freissmuth M., Palmer S. Phosphorylation of the spliced variant forms of the recombinant stimulatory guanine-nucleotide-binding regulatory protein (Gs alpha) by protein kinase C. Biochem J 1992, 285(Pt 1):333-338.
-
(1992)
Biochem J
, vol.285
, Issue.PART 1
, pp. 333-338
-
-
Pyne, N.J.1
Freissmuth, M.2
Palmer, S.3
-
156
-
-
0029635377
-
Phosphorylation and activation of β-adrenergic receptor kinase by protein kinase C
-
Chuang T.T., LeVine H., De B.A. Phosphorylation and activation of β-adrenergic receptor kinase by protein kinase C. J Biol Chem 1995, 270:18660-18665.
-
(1995)
J Biol Chem
, vol.270
, pp. 18660-18665
-
-
Chuang, T.T.1
LeVine, H.2
De, B.A.3
-
157
-
-
0030296744
-
G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications
-
Chuang T.T., Iacovelli L., Sallese M., De B.A. G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications. Trends Pharmacol Sci 1996, 17:416-421.
-
(1996)
Trends Pharmacol Sci
, vol.17
, pp. 416-421
-
-
Chuang, T.T.1
Iacovelli, L.2
Sallese, M.3
De, B.A.4
-
159
-
-
74549139733
-
Potential for long-acting muscarinic antagonists in chronic obstructive pulmonary disease
-
Joos G.F. Potential for long-acting muscarinic antagonists in chronic obstructive pulmonary disease. Expert Opin Investig Drugs 2010, 19:257-264.
-
(2010)
Expert Opin Investig Drugs
, vol.19
, pp. 257-264
-
-
Joos, G.F.1
-
160
-
-
79961016525
-
Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial
-
Kerstjens H.A.M., Disse B., Schroder-Babo W., Bantje T.A., Gahlemann M., Sigmund R., et al. Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial. J Allergy Clin Immunol 2011, 128:308-314.
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 308-314
-
-
Kerstjens, H.A.M.1
Disse, B.2
Schroder-Babo, W.3
Bantje, T.A.4
Gahlemann, M.5
Sigmund, R.6
-
161
-
-
77952914041
-
Combining tiotropium and salmeterol in COPD: effects on airflow obstruction and symptoms
-
van Noord J.A., Aumann J.L., Janssens E., Smeets J.J., Zaagsma J., Mueller A., et al. Combining tiotropium and salmeterol in COPD: effects on airflow obstruction and symptoms. Respir Med 2010, 104:995-1004.
-
(2010)
Respir Med
, vol.104
, pp. 995-1004
-
-
van Noord, J.A.1
Aumann, J.L.2
Janssens, E.3
Smeets, J.J.4
Zaagsma, J.5
Mueller, A.6
-
162
-
-
78649635656
-
QVA149 demonstrates superior bronchodilation compared with indacaterol or placebo in patients with chronic obstructive pulmonary disease
-
van Noord J.A., Buhl R., Laforce C., Martin C., Jones F., Dolker M., et al. QVA149 demonstrates superior bronchodilation compared with indacaterol or placebo in patients with chronic obstructive pulmonary disease. Thorax 2010, 65:1086-1091.
-
(2010)
Thorax
, vol.65
, pp. 1086-1091
-
-
van Noord, J.A.1
Buhl, R.2
Laforce, C.3
Martin, C.4
Jones, F.5
Dolker, M.6
-
163
-
-
84863524497
-
The bronchoprotective effect of olodaterol against histamine is synergistically enhanced and prolonged by tiotropium
-
Smit M., Zuidhof A.B., Bos I.S.T., Maarsingh H., Gosens R., Zaagsma J., et al. The bronchoprotective effect of olodaterol against histamine is synergistically enhanced and prolonged by tiotropium. Am J Respir Crit Care Med 2011, 183:A1379.
-
(2011)
Am J Respir Crit Care Med
, vol.183
-
-
Smit, M.1
Zuidhof, A.B.2
Bos, I.S.T.3
Maarsingh, H.4
Gosens, R.5
Zaagsma, J.6
-
164
-
-
84873139771
-
Acute reversal of allergen-induced airway hyperresponsiveness (AHR) by olodaterol is synergistically enhanced by tiotropium bromide
-
Smit M., Zuidhof A.B., Bos I.S.T., Maarsingh H., Gosens R., Zaagsma J., et al. Acute reversal of allergen-induced airway hyperresponsiveness (AHR) by olodaterol is synergistically enhanced by tiotropium bromide. Eur Respir J 2011, 38(Suppl. 55):306S.
-
(2011)
Eur Respir J
, vol.38
, Issue.SUPPL. 55
-
-
Smit, M.1
Zuidhof, A.B.2
Bos, I.S.T.3
Maarsingh, H.4
Gosens, R.5
Zaagsma, J.6
-
165
-
-
0031761533
-
Characteristics of airway hyperresponsiveness in asthma and chronic obstructive pulmonary disease
-
Postma D.S., Kerstjens H.A.M. Characteristics of airway hyperresponsiveness in asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998, 158:S187-S192.
-
(1998)
Am J Respir Crit Care Med
, vol.158
-
-
Postma, D.S.1
Kerstjens, H.A.M.2
-
166
-
-
0037470640
-
The non-neuronal cholinergic system in humans: expression, function and pathophysiology
-
Wessler I., Kilbinger H., Bittinger F., Unger R., Kirkpatrick C.J. The non-neuronal cholinergic system in humans: expression, function and pathophysiology. Life Sci 2003, 72:2055-2061.
-
(2003)
Life Sci
, vol.72
, pp. 2055-2061
-
-
Wessler, I.1
Kilbinger, H.2
Bittinger, F.3
Unger, R.4
Kirkpatrick, C.J.5
-
167
-
-
77953123408
-
Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD
-
Wollin L., Pieper M.P. Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD. Pulm Pharmacol Ther 2010, 23:345-354.
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 345-354
-
-
Wollin, L.1
Pieper, M.P.2
-
168
-
-
33846885909
-
Bilateral vagotomy or atropine pre-treatment reduces experimental diesel-soot induced lung inflammation
-
McQueen D.S., Donaldson K., Bond S.M., McNeilly J.D., Newman S., Barton N.J., et al. Bilateral vagotomy or atropine pre-treatment reduces experimental diesel-soot induced lung inflammation. Toxicol Appl Pharmacol 2007, 219:62-71.
-
(2007)
Toxicol Appl Pharmacol
, vol.219
, pp. 62-71
-
-
McQueen, D.S.1
Donaldson, K.2
Bond, S.M.3
McNeilly, J.D.4
Newman, S.5
Barton, N.J.6
-
169
-
-
80052940501
-
Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD
-
Pera T., Zuidhof A., Valadas J., Smit M., Schoemaker R.G., Gosens R., et al. Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD. Eur Respir J 2011, 38:789-796.
-
(2011)
Eur Respir J
, vol.38
, pp. 789-796
-
-
Pera, T.1
Zuidhof, A.2
Valadas, J.3
Smit, M.4
Schoemaker, R.G.5
Gosens, R.6
-
170
-
-
84873158857
-
A critical role of muscarinic receptors in bleomycin-induced lung inflammation and fibrosis
-
Nishioka T., Ikeda M., Fukuchi K., Tishi T. A critical role of muscarinic receptors in bleomycin-induced lung inflammation and fibrosis. Am J Respir Crit Care Med 2009, 179:A3426.
-
(2009)
Am J Respir Crit Care Med
, vol.179
-
-
Nishioka, T.1
Ikeda, M.2
Fukuchi, K.3
Tishi, T.4
-
171
-
-
77954357471
-
Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma
-
Ohta S., Oda N., Yokoe T., Tanaka A., Yamamoto Y., Watanabe Y., et al. Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma. Clin Exp Allergy 2010, 40:1266-1275.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 1266-1275
-
-
Ohta, S.1
Oda, N.2
Yokoe, T.3
Tanaka, A.4
Yamamoto, Y.5
Watanabe, Y.6
-
172
-
-
78049265848
-
Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation
-
Damera G., Jiang M., Zhao H., Fogle H.W., Jester W.F., Freire J., et al. Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation. Eur J Pharmacol 2010, 649:349-353.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 349-353
-
-
Damera, G.1
Jiang, M.2
Zhao, H.3
Fogle, H.W.4
Jester, W.F.5
Freire, J.6
-
173
-
-
79952534622
-
3 muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice
-
3 muscarinic receptor antagonist bencycloquidium bromide attenuates allergic airway inflammation, hyperresponsiveness and remodeling in mice. Eur J Pharmacol 2011, 655:83-90.
-
(2011)
Eur J Pharmacol
, vol.655
, pp. 83-90
-
-
Cao, R.1
Dong, X.W.2
Jiang, J.X.3
Yan, X.F.4
He, J.S.5
Deng, Y.M.6
-
174
-
-
38449113726
-
Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison
-
Bos I.S.T., Gosens R., Zuidhof A.B., Schaafsma D., Halayko A.J., Meurs H., et al. Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison. Eur Respir J 2007, 30:653-661.
-
(2007)
Eur Respir J
, vol.30
, pp. 653-661
-
-
Bos, I.S.T.1
Gosens, R.2
Zuidhof, A.B.3
Schaafsma, D.4
Halayko, A.J.5
Meurs, H.6
-
175
-
-
77953522835
-
Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux
-
Cui Y., Devillier P., Kuang X., Wang H., Zhu L., Xu Z., et al. Tiotropium reduction of lung inflammation in a model of chronic gastro-oesophageal reflux. Eur Respir J 2010, 35:1370-1376.
-
(2010)
Eur Respir J
, vol.35
, pp. 1370-1376
-
-
Cui, Y.1
Devillier, P.2
Kuang, X.3
Wang, H.4
Zhu, L.5
Xu, Z.6
-
176
-
-
77957307358
-
Effects of formoterol and ipratropium bromide on repeated cadmium inhalation-induced pulmonary inflammation and emphysema in rats
-
Zhang W., Fievez L., Zhang F., Cheu E., Antoine N., Delguste C., et al. Effects of formoterol and ipratropium bromide on repeated cadmium inhalation-induced pulmonary inflammation and emphysema in rats. Eur J Pharmacol 2010, 647:178-187.
-
(2010)
Eur J Pharmacol
, vol.647
, pp. 178-187
-
-
Zhang, W.1
Fievez, L.2
Zhang, F.3
Cheu, E.4
Antoine, N.5
Delguste, C.6
-
178
-
-
34748819974
-
Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro
-
Buhling F., Lieder N., Kuhlmann U.C., Waldburg N., Welte T. Tiotropium suppresses acetylcholine-induced release of chemotactic mediators in vitro. Respir Med 2007, 101:2386-2394.
-
(2007)
Respir Med
, vol.101
, pp. 2386-2394
-
-
Buhling, F.1
Lieder, N.2
Kuhlmann, U.C.3
Waldburg, N.4
Welte, T.5
-
179
-
-
79951951764
-
Inhibition of granulocyte migration by tiotropium bromide
-
Vacca G., Randerath W.J., Gillissen A. Inhibition of granulocyte migration by tiotropium bromide. Respir Res 2011, 12:24.
-
(2011)
Respir Res
, vol.12
, pp. 24
-
-
Vacca, G.1
Randerath, W.J.2
Gillissen, A.3
-
180
-
-
0026697298
-
Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity
-
Koyama S., Rennard S.I., Robbins R.A. Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity. Am J Physiol 1992, 262:L466-L471.
-
(1992)
Am J Physiol
, vol.262
-
-
Koyama, S.1
Rennard, S.I.2
Robbins, R.A.3
-
181
-
-
0031957332
-
Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity
-
Koyama S., Sato E., Nomura H., Kubo K., Nagai S., Izumi T. Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity. J Appl Physiol 1998, 84:1528-1534.
-
(1998)
J Appl Physiol
, vol.84
, pp. 1528-1534
-
-
Koyama, S.1
Sato, E.2
Nomura, H.3
Kubo, K.4
Nagai, S.5
Izumi, T.6
-
183
-
-
39149132101
-
Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFκ B/ERK-dependent mechanism
-
Profita M., Bonanno A., Siena L., Ferraro M., Montalbano A.M., Pompeo F., et al. Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFκ B/ERK-dependent mechanism. Eur J Pharmacol 2008, 582:145-153.
-
(2008)
Eur J Pharmacol
, vol.582
, pp. 145-153
-
-
Profita, M.1
Bonanno, A.2
Siena, L.3
Ferraro, M.4
Montalbano, A.M.5
Pompeo, F.6
-
184
-
-
79959346315
-
Cigarette smoke extract activates human bronchial epithelial cells affecting non-neuronal cholinergic system signalling in vitro
-
Profita M., Bonanno A., Montalbano A.M., Ferraro M., Siena L., Bruno A., et al. Cigarette smoke extract activates human bronchial epithelial cells affecting non-neuronal cholinergic system signalling in vitro. Life Sci 2011, 89:36-43.
-
(2011)
Life Sci
, vol.89
, pp. 36-43
-
-
Profita, M.1
Bonanno, A.2
Montalbano, A.M.3
Ferraro, M.4
Siena, L.5
Bruno, A.6
-
185
-
-
0027326410
-
Protein kinase Cα activates RAF-1 by direct phosphorylation
-
Kolch W., Heidecker G., Kochs G., Hummel R., Vahidi H., Mischak H., et al. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature 1993, 364:249-252.
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
Mischak, H.6
-
186
-
-
0033551804
-
Protein kinase C and calcineurin synergize to activate Iκ B kinase and NF-κ B in T lymphocytes
-
Trushin S.A., Pennington K.N., geciras-Schimnich A., Paya C.V. Protein kinase C and calcineurin synergize to activate Iκ B kinase and NF-κ B in T lymphocytes. J Biol Chem 1999, 274:22923-22931.
-
(1999)
J Biol Chem
, vol.274
, pp. 22923-22931
-
-
Trushin, S.A.1
Pennington, K.N.2
geciras-Schimnich, A.3
Paya, C.V.4
-
187
-
-
79551608638
-
Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle
-
Oenema T.A., Kolahian S., Nanninga J.E., Rieks D., Hiemstra P.S., Zuyderduyn S., et al. Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle. Respir Res 2010, 11:130.
-
(2010)
Respir Res
, vol.11
, pp. 130
-
-
Oenema, T.A.1
Kolahian, S.2
Nanninga, J.E.3
Rieks, D.4
Hiemstra, P.S.5
Zuyderduyn, S.6
-
188
-
-
73549115088
-
The disruption of the epithelial mesenchymal trophic unit in COPD
-
Behzad A.R., McDonough J.E., Seyednejad N., Hogg J.C., Walker D.C. The disruption of the epithelial mesenchymal trophic unit in COPD. COPD 2009, 6:421-431.
-
(2009)
COPD
, vol.6
, pp. 421-431
-
-
Behzad, A.R.1
McDonough, J.E.2
Seyednejad, N.3
Hogg, J.C.4
Walker, D.C.5
-
189
-
-
74849104632
-
The role of the epithelium in airway remodeling in asthma
-
Davies D.E. The role of the epithelium in airway remodeling in asthma. Proc Am Thorac Soc 2009, 6:678-682.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 678-682
-
-
Davies, D.E.1
-
190
-
-
18644380685
-
Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling
-
Gosens R., Bos I.S.T., Zaagsma J., Meurs H. Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling. Am J Respir Crit Care Med 2005, 171:1096-1102.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1096-1102
-
-
Gosens, R.1
Bos, I.S.T.2
Zaagsma, J.3
Meurs, H.4
-
191
-
-
77951962428
-
Inhibition of neutrophil elastase-induced goblet cell metaplasia by tiotropium in mice
-
Arai N., Kondo M., Izumo T., Tamaoki J., Nagai A. Inhibition of neutrophil elastase-induced goblet cell metaplasia by tiotropium in mice. Eur Respir J 2010, 35:1164-1171.
-
(2010)
Eur Respir J
, vol.35
, pp. 1164-1171
-
-
Arai, N.1
Kondo, M.2
Izumo, T.3
Tamaoki, J.4
Nagai, A.5
-
192
-
-
34249284422
-
MAPK pathway mediates muscarinic receptor-induced human lung fibroblast proliferation
-
Matthiesen S., Bahulayan A., Holz O., Racké K. MAPK pathway mediates muscarinic receptor-induced human lung fibroblast proliferation. Life Sci 2007, 80:2259-2262.
-
(2007)
Life Sci
, vol.80
, pp. 2259-2262
-
-
Matthiesen, S.1
Bahulayan, A.2
Holz, O.3
Racké, K.4
-
193
-
-
34249338661
-
Acetylcholine-induced proliferation of fibroblasts and myofibroblasts in vitro is inhibited by tiotropium bromide
-
Pieper M.P., Chaudhary N.I., Park J.E. Acetylcholine-induced proliferation of fibroblasts and myofibroblasts in vitro is inhibited by tiotropium bromide. Life Sci 2007, 80:2270-2273.
-
(2007)
Life Sci
, vol.80
, pp. 2270-2273
-
-
Pieper, M.P.1
Chaudhary, N.I.2
Park, J.E.3
-
194
-
-
65649151058
-
Smoke, choline acetyltransferase, muscarinic receptors, and fibroblast proliferation in chronic obstructive pulmonary disease
-
Profita M., Bonanno A., Siena L., Bruno A., Ferraro M., Montalbano A.M., et al. Smoke, choline acetyltransferase, muscarinic receptors, and fibroblast proliferation in chronic obstructive pulmonary disease. J Pharmacol Exp Ther 2009, 329:753-763.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 753-763
-
-
Profita, M.1
Bonanno, A.2
Siena, L.3
Bruno, A.4
Ferraro, M.5
Montalbano, A.M.6
-
196
-
-
36348937450
-
Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation
-
Gosens R., Dueck G., Rector E., Nunes R.O., Gerthoffer W.T., Unruh H., et al. Cooperative regulation of GSK-3 by muscarinic and PDGF receptors is associated with airway myocyte proliferation. Am J Physiol Lung Cell Mol Physiol 2007, 293:L1348-L1358.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Gosens, R.1
Dueck, G.2
Rector, E.3
Nunes, R.O.4
Gerthoffer, W.T.5
Unruh, H.6
-
197
-
-
27644491911
-
Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth
-
Billington C.K., Kong K.C., Bhattacharyya R., Wedegaertner P.B., Panettieri R.A., Chan T.O., et al. Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth. Biochemistry 2005, 44:14595-14605.
-
(2005)
Biochemistry
, vol.44
, pp. 14595-14605
-
-
Billington, C.K.1
Kong, K.C.2
Bhattacharyya, R.3
Wedegaertner, P.B.4
Panettieri, R.A.5
Chan, T.O.6
-
199
-
-
84857444788
-
Aclidinium inhibits human lung fibroblast to myofibroblast transition
-
Milara J., Serrano A., Peiro T., Gavalda A., Miralpeix M., Morcillo E.J., et al. Aclidinium inhibits human lung fibroblast to myofibroblast transition. Thorax 2012, 67:229-237.
-
(2012)
Thorax
, vol.67
, pp. 229-237
-
-
Milara, J.1
Serrano, A.2
Peiro, T.3
Gavalda, A.4
Miralpeix, M.5
Morcillo, E.J.6
-
200
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
-
Wipff P.J., Rifkin D.B., Meister J.J., Hinz B. Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix. J Cell Biol 2007, 179:1311-1323.
-
(2007)
J Cell Biol
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
201
-
-
82755189233
-
Integrin alphavbeta5-mediated TGF-β activation by airway smooth muscle cells in asthma
-
Tatler A.L., John A.E., Jolly L., Habgood A., Porte J., Brightling C., et al. Integrin alphavbeta5-mediated TGF-β activation by airway smooth muscle cells in asthma. J Immunol 2011, 187:6094-6107.
-
(2011)
J Immunol
, vol.187
, pp. 6094-6107
-
-
Tatler, A.L.1
John, A.E.2
Jolly, L.3
Habgood, A.4
Porte, J.5
Brightling, C.6
-
202
-
-
33645679788
-
Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM
-
Kanefsky J., Lenburg M., Hai C.M. Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM. Am J Respir Cell Mol Biol 2006, 34:417-425.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 417-425
-
-
Kanefsky, J.1
Lenburg, M.2
Hai, C.M.3
-
203
-
-
52649100121
-
Airway smooth muscle cell tone amplifies contractile function in the presence of chronic cyclic strain
-
Fairbank N.J., Connolly S.C., Mackinnon J.D., Wehry K., Deng L., Maksym G.N. Airway smooth muscle cell tone amplifies contractile function in the presence of chronic cyclic strain. Am J Physiol Lung Cell Mol Physiol 2008, 295:L479-L488.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Fairbank, N.J.1
Connolly, S.C.2
Mackinnon, J.D.3
Wehry, K.4
Deng, L.5
Maksym, G.N.6
-
204
-
-
79957512933
-
Effect of bronchoconstriction on airway remodeling in asthma
-
Grainge C.L., Lau L.C., Ward J.A., Dulay V., Lahiff G., Wilson S., et al. Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 2011, 364:2006-2015.
-
(2011)
N Engl J Med
, vol.364
, pp. 2006-2015
-
-
Grainge, C.L.1
Lau, L.C.2
Ward, J.A.3
Dulay, V.4
Lahiff, G.5
Wilson, S.6
-
205
-
-
84873145382
-
TGFβ1-induced extracellular matrix production enhances airway smooth muscle cell proliferation
-
Oenema T.A., Smedinga L., Mensink G., Halayko A.J., Zaagsma J., Meurs H., et al. TGFβ1-induced extracellular matrix production enhances airway smooth muscle cell proliferation. Eur Respir J 2011, 38(Suppl. 55):121S.
-
(2011)
Eur Respir J
, vol.38
, Issue.SUPPL. 55
-
-
Oenema, T.A.1
Smedinga, L.2
Mensink, G.3
Halayko, A.J.4
Zaagsma, J.5
Meurs, H.6
-
206
-
-
79960973276
-
Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma
-
Bateman E.D., Kornmann O., Schmidt P., Pivovarova A., Engel M., Fabbri L.M. Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma. J Allergy Clin Immunol 2011, 128:315-322.
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 315-322
-
-
Bateman, E.D.1
Kornmann, O.2
Schmidt, P.3
Pivovarova, A.4
Engel, M.5
Fabbri, L.M.6
-
207
-
-
77957768543
-
Tiotropium bromide step-up therapy for adults with uncontrolled asthma
-
Peters S.P., Kunselman S.J., Icitovic N., Moore W.C., Pascual R., Ameredes B.T., et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med 2010, 363:1715-1726.
-
(2010)
N Engl J Med
, vol.363
, pp. 1715-1726
-
-
Peters, S.P.1
Kunselman, S.J.2
Icitovic, N.3
Moore, W.C.4
Pascual, R.5
Ameredes, B.T.6
-
208
-
-
47149117849
-
Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma
-
Penn R.B. Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma. Naunyn Schmiedebergs Arch Pharmacol 2008, 378:149-169.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 149-169
-
-
Penn, R.B.1
|