Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD

European Respiratory Journal

Volumn 38, Issue 4, 2011, Pages 789-796

  Pera, T ^a   Zuidhof, A ^a   Valadas, J ^a   Smit, M ^a   Schoemaker, R G ^b   Gosens, R ^a   Maarsingh, H ^a   Zaagsma, J ^a   Meurs, H ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Airway remodelling; Emphysema; Fibrosis; Lipopolysaccharide; Non neuronal acetylcholine; Pulmonary vascular remodelling

Indexed keywords

ACETYLCHOLINE; COLLAGEN; HYDROXYPROLINE; LIPOPOLYSACCHARIDE; MUCIN 5AC; TIOTROPIUM BROMIDE;

ADVENTITIA; AIRWAY; AIRWAY REMODELING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGINOUS TISSUE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GOBLET CELL; GUINEA PIG; HISTOPATHOLOGY; LUNG BLOOD VESSEL; LUNG EMPHYSEMA; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; NEUTROPHIL COUNT; NEUTROPHILIA; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT DURATION;

ACETYLCHOLINE; AIRWAY REMODELING; ANIMALS; ANIMALS, OUTBRED STRAINS; CHOLINERGIC ANTAGONISTS; DISEASE MODELS, ANIMAL; EMPHYSEMA; GOBLET CELLS; GUINEA PIGS; LIPOPOLYSACCHARIDES; LUNG; MALE; MUCIN 5AC; MUSCARINIC ANTAGONISTS; NEUTROPHILS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY FIBROSIS; SCOPOLAMINE DERIVATIVES;

EID: 80052940501     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00146610     Document Type: Article

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