Acetylcholine-induced proliferation of fibroblasts and myofibroblasts in vitro is inhibited by tiotropium bromide

Life Sciences

Volumn 80, Issue 24-25, 2007, Pages 2270-2273

  Pieper, M P ^a   Chaudhary, N I ^a   Park, J E ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Airway remodeling; Fibroblast; M3 muscarinic receptor; Myofibroblast; Proliferation; Tiotropium

Indexed keywords

ACETYLCHOLINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; RECEPTOR SUBTYPE; TIOTROPIUM BROMIDE;

ARTICLE; CELL PROLIFERATION; CHOLINERGIC STIMULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FIBROBLAST; HUMAN; HUMAN CELL; LUNG BIOPSY; MYOFIBROBLAST; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYLCHOLINE; ACTINS; CELL PROLIFERATION; CELLS, CULTURED; CHOLINERGIC AGENTS; CHOLINERGIC ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; MYOCYTES, SMOOTH MUSCLE; PULMONARY FIBROSIS; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCOPOLAMINE DERIVATIVES;

EID: 34249338661     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.02.034     Document Type: Article

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