메뉴 건너뛰기




Volumn 30, Issue 4, 2007, Pages 653-661

Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: A comparison

Author keywords

Airway remodelling; Airway smooth muscle; Anticholinergics; Asthma; Glucocorticosteroids; Mucus hypersecretion

Indexed keywords

ALLERGEN; BUDESONIDE; MYOSIN; OVALBUMIN; TIOTROPIUM BROMIDE; BRONCHODILATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; GLUCOCORTICOID; SCOPOLAMINE DERIVATIVE; TIOTROPIUM; UNCLASSIFIED DRUG;

EID: 38449113726     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.00004907     Document Type: Article
Times cited : (190)

References (45)
  • 2
    • 33745218112 scopus 로고    scopus 로고
    • Muscarinic receptor signaling in the pathophysiology of asthma and COPD
    • Gosens R, Zaagsma J, Meurs H, Halayko AJ. Muscarinic receptor signaling in the pathophysiology of asthma and COPD. Respir Res 2006; 7: 73.
    • (2006) Respir Res , vol.7 , pp. 73
    • Gosens, R.1    Zaagsma, J.2    Meurs, H.3    Halayko, A.J.4
  • 3
    • 3042525451 scopus 로고    scopus 로고
    • The airway cholinergic system: Physiology and pharmacology
    • Racke K, Matthiesen S. The airway cholinergic system: physiology and pharmacology. Pulm Pharmacol Ther 2004; 17: 181-198.
    • (2004) Pulm Pharmacol Ther , vol.17 , pp. 181-198
    • Racke, K.1    Matthiesen, S.2
  • 5
    • 27644530096 scopus 로고    scopus 로고
    • Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease
    • discussion 311-312
    • Belmonte KE. Cholinergic pathways in the lungs and anticholinergic therapy for chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005; 2: 297-304; discussion 311-312.
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 297-304
    • Belmonte, K.E.1
  • 7
    • 0025191514 scopus 로고
    • 3 receptors mediate contraction of human central and peripheral airway smooth muscle
    • 3 receptors mediate contraction of human central and peripheral airway smooth muscle. Pulm Pharmacol 1990; 3: 47-51.
    • (1990) Pulm Pharmacol , vol.3 , pp. 47-51
    • Roffel, A.F.1    Elzinga, C.R.2    Zaagsma, J.3
  • 9
    • 0026506533 scopus 로고
    • Muscarinic receptor subtypes in feline tracheal submucosal gland secretion
    • Ishihara H, Shimura S, Satoh M, et al. Muscarinic receptor subtypes in feline tracheal submucosal gland secretion. Am J Physiol 1992; 262: L223-L228.
    • (1992) Am J Physiol , vol.262
    • Ishihara, H.1    Shimura, S.2    Satoh, M.3
  • 10
    • 0021175444 scopus 로고
    • Role of the parasympathetic system in airway obstruction due to emphysema
    • Gross NJ, Skorodin MS. Role of the parasympathetic system in airway obstruction due to emphysema. N Engl J Med 1984; 311: 421-425.
    • (1984) N Engl J Med , vol.311 , pp. 421-425
    • Gross, N.J.1    Skorodin, M.S.2
  • 12
    • 4644346591 scopus 로고    scopus 로고
    • Gaq-receptor coupled signaling induces RHO-dependent transcription of smooth muscle specific genes in cultured canine airway myocytes
    • Liu HW, Kassiri K, Voros A, et al. Gaq-receptor coupled signaling induces RHO-dependent transcription of smooth muscle specific genes in cultured canine airway myocytes. Am J Respir Crit Care Med 2002; 165: A670.
    • (2002) Am J Respir Crit Care Med , vol.165
    • Liu, H.W.1    Kassiri, K.2    Voros, A.3
  • 13
    • 33845397124 scopus 로고    scopus 로고
    • Muscarinic receptors mediate stimulation of human lung fibroblast proliferation
    • Matthiesen S, Bahulayan A, Kempkens S, et al. Muscarinic receptors mediate stimulation of human lung fibroblast proliferation. Am J Respir Cell Mol Biol 2006; 35: 621-627.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 621-627
    • Matthiesen, S.1    Bahulayan, A.2    Kempkens, S.3
  • 14
    • 33645679788 scopus 로고    scopus 로고
    • Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM
    • Kanefsky J, Lenburg M, Hai CM. Cholinergic receptor and cyclic stretch-mediated inflammatory gene expression in intact ASM. Am J Respir Cell Mol Biol 2006; 34: 417-425.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 417-425
    • Kanefsky, J.1    Lenburg, M.2    Hai, C.M.3
  • 15
    • 0026697298 scopus 로고
    • Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity
    • Koyama S, Rennard SI, Robbins RA. Acetylcholine stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity. Am J Physiol 1992; 262: L466-L471.
    • (1992) Am J Physiol , vol.262
    • Koyama, S.1    Rennard, S.I.2    Robbins, R.A.3
  • 16
    • 0031957332 scopus 로고    scopus 로고
    • Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity
    • Koyama S, Sato E, Nomura H, Kubo K, Nagai S, Izumi T. Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity. J Appl Physiol 1998; 84: 1528-1534.
    • (1998) J Appl Physiol , vol.84 , pp. 1528-1534
    • Koyama, S.1    Sato, E.2    Nomura, H.3    Kubo, K.4    Nagai, S.5    Izumi, T.6
  • 17
    • 0031778288 scopus 로고    scopus 로고
    • Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity
    • Sato E, Koyama S, Okubo Y, Kubo K, Sekiguchi M. Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. Am J Physiol 1998; 274: L970-L979.
    • (1998) Am J Physiol , vol.274
    • Sato, E.1    Koyama, S.2    Okubo, Y.3    Kubo, K.4    Sekiguchi, M.5
  • 18
    • 26944437890 scopus 로고    scopus 로고
    • 4 production and neutrophilic inflammation in COPD patients
    • 4 production and neutrophilic inflammation in COPD patients. Allergy 2005; 60: 1361-1369.
    • (2005) Allergy , vol.60 , pp. 1361-1369
    • Profita, M.1    Giorgi, R.D.2    Sala, A.3
  • 19
    • 18644380685 scopus 로고    scopus 로고
    • Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling
    • Gosens R, Bos IS, Zaagsma J, Meurs H. Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling. Am J Respir Crit Care Med 2005; 171: 1096-1102.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1096-1102
    • Gosens, R.1    Bos, I.S.2    Zaagsma, J.3    Meurs, H.4
  • 20
    • 34548751788 scopus 로고    scopus 로고
    • A guinea pig model of acute and chronic asthma using permanently instrumented and unrestrained animals
    • Meurs H, Santing RE, Remie R, et al. A guinea pig model of acute and chronic asthma using permanently instrumented and unrestrained animals. Nat Protoc 2006; 1: 840-847.
    • (2006) Nat Protoc , vol.1 , pp. 840-847
    • Meurs, H.1    Santing, R.E.2    Remie, R.3
  • 22
    • 33745646074 scopus 로고    scopus 로고
    • Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro
    • Chorley BN, Crews AL, Li Y, Adler KB, Minnicozzi M, Martin LD. Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. Respir Res 2006; 7: 35.
    • (2006) Respir Res , vol.7 , pp. 35
    • Chorley, B.N.1    Crews, A.L.2    Li, Y.3    Adler, K.B.4    Minnicozzi, M.5    Martin, L.D.6
  • 23
    • 38849112989 scopus 로고    scopus 로고
    • National Institutes of Health, ImageJ. Image Processing and Analysis in Java. http://rsb.info.nih.gov/ij/index.html Date last updated: July 23, 2007. Date last accessed: August 7, 2007.
    • National Institutes of Health, ImageJ. Image Processing and Analysis in Java. http://rsb.info.nih.gov/ij/index.html Date last updated: July 23, 2007. Date last accessed: August 7, 2007.
  • 25
    • 0035891664 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive lung disease
    • Jeffery PK. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001; 164: S28-S38.
    • (2001) Am J Respir Crit Care Med , vol.164
    • Jeffery, P.K.1
  • 26
    • 33745855449 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive pulmonary disease
    • Postma DS, Timens W. Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3: 434-439.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 434-439
    • Postma, D.S.1    Timens, W.2
  • 27
    • 0035218725 scopus 로고    scopus 로고
    • Mucus hypersecretion in chronic obstructive pulmonary disease
    • Rogers DF. Mucus hypersecretion in chronic obstructive pulmonary disease. Novartis Found Symp 2001; 234: 65-83.
    • (2001) Novartis Found Symp , vol.234 , pp. 65-83
    • Rogers, D.F.1
  • 28
    • 2342523999 scopus 로고    scopus 로고
    • Airway mucus hypersecretion in asthma: An undervalued pathology?
    • Rogers DF. Airway mucus hypersecretion in asthma: an undervalued pathology? Curr Opin Pharmacol 2004; 4: 241-250.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 241-250
    • Rogers, D.F.1
  • 29
    • 0029999720 scopus 로고    scopus 로고
    • Regulation of MUC5 and MUC1 gene expression: Correlation with airway mucous differentiation
    • Guzman K, Bader T, Nettesheim P. Regulation of MUC5 and MUC1 gene expression: correlation with airway mucous differentiation. Am J Physiol 1996; 270: L846-L853.
    • (1996) Am J Physiol , vol.270
    • Guzman, K.1    Bader, T.2    Nettesheim, P.3
  • 30
    • 0031834909 scopus 로고    scopus 로고
    • Platelet-activating factor induces goblet cell hyperplasia and mucin gene expression in airways
    • Lou YP, Takeyama K, Grattan KM, et al. Platelet-activating factor induces goblet cell hyperplasia and mucin gene expression in airways. Am J Respir Crit Care Med 1998; 157: 1927-1934.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1927-1934
    • Lou, Y.P.1    Takeyama, K.2    Grattan, K.M.3
  • 31
    • 0035084065 scopus 로고    scopus 로고
    • Fluticasone inhibits but does not reverse allergen-induced structural airway changes
    • Vanacker NJ, Palmans E, Kips JC, Pauwels RA. Fluticasone inhibits but does not reverse allergen-induced structural airway changes. Am J Respir Crit Care Med 2001; 163: 674-679.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 674-679
    • Vanacker, N.J.1    Palmans, E.2    Kips, J.C.3    Pauwels, R.A.4
  • 32
    • 12944255788 scopus 로고    scopus 로고
    • Airway wall remodelling: The influence of corticosteroids
    • Ward C, Walters H. Airway wall remodelling: the influence of corticosteroids. Curr Opin Allergy Clin Immunol 2005; 5: 43-48.
    • (2005) Curr Opin Allergy Clin Immunol , vol.5 , pp. 43-48
    • Ward, C.1    Walters, H.2
  • 33
    • 0037376683 scopus 로고    scopus 로고
    • Cholinergic agonists transactivate EGFR and stimulate MAPK to induce goblet cell secretion
    • Kanno H, Horikawa Y, Hodges RR, et al. Cholinergic agonists transactivate EGFR and stimulate MAPK to induce goblet cell secretion. Am J Physiol Cell Physiol 2003; 284: C988-C998.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Kanno, H.1    Horikawa, Y.2    Hodges, R.R.3
  • 34
    • 0035126934 scopus 로고    scopus 로고
    • Motor control of airway goblet cells and glands
    • Rogers DF. Motor control of airway goblet cells and glands. Respir Physiol 2001; 125: 129-144.
    • (2001) Respir Physiol , vol.125 , pp. 129-144
    • Rogers, D.F.1
  • 35
    • 0035683136 scopus 로고    scopus 로고
    • The non-neuronal cholinergic system: An emerging drug target in the airways
    • Wessler IK, Kirkpatrick CJ. The non-neuronal cholinergic system: an emerging drug target in the airways. Pulm Pharmacol Ther 2001; 14: 423-434.
    • (2001) Pulm Pharmacol Ther , vol.14 , pp. 423-434
    • Wessler, I.K.1    Kirkpatrick, C.J.2
  • 36
    • 2042443069 scopus 로고    scopus 로고
    • Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells
    • Proskocil BJ, Sekhon HS, Jia Y, et al. Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. Endocrinology 2004; 145: 2498-2506.
    • (2004) Endocrinology , vol.145 , pp. 2498-2506
    • Proskocil, B.J.1    Sekhon, H.S.2    Jia, Y.3
  • 37
    • 21844457187 scopus 로고    scopus 로고
    • Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium
    • Lips KS, Volk C, Schmitt BM, et al. Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. Am J Respir Cell Mol Biol 2005; 33: 79-88.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 79-88
    • Lips, K.S.1    Volk, C.2    Schmitt, B.M.3
  • 38
    • 33646856174 scopus 로고    scopus 로고
    • Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse
    • Kummer W, Wiegand S, Akinci S, et al. Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse. Respir Res 2006; 7: 65.
    • (2006) Respir Res , vol.7 , pp. 65
    • Kummer, W.1    Wiegand, S.2    Akinci, S.3
  • 39
    • 33646736505 scopus 로고    scopus 로고
    • Airway smooth muscle phenotype and function: Interactions with current asthma therapies
    • Halayko AJ, Tran T, Ji SY, Yamasaki A, Gosens R. Airway smooth muscle phenotype and function: interactions with current asthma therapies. Curr Drug Targets 2006; 7: 525-540.
    • (2006) Curr Drug Targets , vol.7 , pp. 525-540
    • Halayko, A.J.1    Tran, T.2    Ji, S.Y.3    Yamasaki, A.4    Gosens, R.5
  • 40
    • 0033161645 scopus 로고    scopus 로고
    • Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle
    • Fernandes D, Guida E, Koutsoubos V, et al. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am J Respir Cell Mol Biol 1999; 21: 77-88.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 77-88
    • Fernandes, D.1    Guida, E.2    Koutsoubos, V.3
  • 41
    • 3442876677 scopus 로고    scopus 로고
    • Dysfunctional interaction of C/EBPα and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells
    • Roth M, Johnson PR, Borger P, et al. Dysfunctional interaction of C/EBPα and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells. N Engl J Med 2004; 351: 560-574.
    • (2004) N Engl J Med , vol.351 , pp. 560-574
    • Roth, M.1    Johnson, P.R.2    Borger, P.3
  • 43
    • 17144403761 scopus 로고    scopus 로고
    • Therapeutic administration of budesonide ameliorates allergen-induced airway remodelling
    • McMillan SJ, Xanthou G, Lloyd CM. Therapeutic administration of budesonide ameliorates allergen-induced airway remodelling. Clin Exp Allergy 2005; 35: 388-396.
    • (2005) Clin Exp Allergy , vol.35 , pp. 388-396
    • McMillan, S.J.1    Xanthou, G.2    Lloyd, C.M.3
  • 44
    • 33645519443 scopus 로고    scopus 로고
    • Treatment of airway mucus hypersecretion
    • Rogers DF, Barnes PJ. Treatment of airway mucus hypersecretion. Ann Med 2006; 38: 116-125.
    • (2006) Ann Med , vol.38 , pp. 116-125
    • Rogers, D.F.1    Barnes, P.J.2
  • 45
    • 0029825959 scopus 로고    scopus 로고
    • Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells
    • Kai H, Yoshitake K, Hisatsune A, et al. Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells. Am J Physiol 1996; 271: L484-L488.
    • (1996) Am J Physiol , vol.271
    • Kai, H.1    Yoshitake, K.2    Hisatsune, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.