Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma

British Journal of Pharmacology

Volumn 165, Issue 5, 2012, Pages 1501-1514

  Buels, K S ^a   Jacoby, D B ^a   Fryer, A D ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

airway hyperreactivity; anticholinergic; asthma; atropine; eosinophil; muscarinic receptors; parasympathetic nerves; tiotropium

Indexed keywords

ACETYLCHOLINE; ATROPINE; OVALBUMIN; TIOTROPIUM BROMIDE;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOACCUMULATION; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CHOLINERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; DRUG EFFICACY; DRUG HALF LIFE; DRUG TARGETING; ELECTROSTIMULATION; EOSINOPHIL; EXPERIMENTAL GUINEA PIG; INFLAMMATORY INFILTRATE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; VAGUS NERVE;

ACETYLCHOLINE; ANIMALS; ASTHMA; ATROPINE; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; DISEASE MODELS, ANIMAL; EOSINOPHILS; FEMALE; GUINEA PIGS; INFLAMMATION; OVALBUMIN; RECEPTOR, MUSCARINIC M3; SCOPOLAMINE DERIVATIVES; VAGUS NERVE;

EID: 84857089767     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01632.x     Document Type: Article

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