Smh-3 induces G2/M arrest and apoptosis through calcium-mediated endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells

Oncology Reports

Volumn 29, Issue 2, 2013, Pages 751-762

  Liu, Chin Yu ^a   Yang, Jai Sing ^a   Huang, Shih Ming ^a   Chiang, Jo Hua ^c   Chen, Ming Hua ^a   Huang, Li Jiau ^a   Ha, Ho Yu ^a   Fushiya, Shinji ^d   Kuo, Sheng Chu ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Endoplasmic reticulum stress; G2 M arrest; Hep3B cells; Smh 3

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM ION; CASPASE 3; CASPASE 4; CASPASE 9; CYCLIN DEPENDENT KINASE 1; DNA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; SMH 3; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CALCIUM TRANSPORT; CANCER INHIBITION; CELL ADHESION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL MIGRATION; CELL VIABILITY; CELLULAR STRESS SIGNAL; CYTOSKELETON; CYTOSOL; DNA DAMAGE; DNA MICROARRAY; DNA REPAIR; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOSIS; MOLECULAR MECHANICS; PRIORITY JOURNAL; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CALCIUM; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CASPASES, INITIATOR; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION PROFILING; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PYRROLIDINES; QUINOLONES; SIGNAL TRANSDUCTION;

EID: 84872781175     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2166     Document Type: Article

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