Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 1, 2005, Pages 265-275

  Lai, Ya Yun ^a   Huang, Li Jiau ^a   Lee, Kuo Hsiung ^b   Xiao, Zhiyan ^b   Bastow, Kenneth F ^b   Yamori, Takao ^c   Kuo, Sheng Chu ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Japan Found Cancer Res T   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 CHLOROPHENYL N (4 CHLOROPHENYL)BENZAMIDE; 3 CHLOROPHENYL N (4 FLUOROPHENYL)BENZAMIDE; 3 CHLOROPHENYL N (4 METHOXYPHENYL)BENZAMIDE; 3 FLUOROPHENYL N (4 CHLOROPHENYL)BENZAMIDE; 3 FLUOROPHENYL N (4 FLUOROPHENYL)BENZAMIDE; 3 FLUOROPHENYL N (4 METHOXYPHENYL)BENZAMIDE; 3 METHOXYPHENYL N (4 CHLOROPHENYL)BENZAMIDE; 3 METHOXYPHENYL N (4 FLUOROPHENYL)BENZAMIDE; 3 METHOXYPHENYL N (4 METHOXYPHENYL)BENZAMIDE; 3' CHLORO 6 FLUORO 2 PHENYL 4 QUINOLONE; 3' METHOXY 6 FLUORO 2 PHENYL 4 QUINOLONE; 3',6 DICHLORO 2 PHENYL 4 QUINOLONE; 3',6 DIFLUORO 2 PHENYL 4 QUINOLONE; ANTIMITOTIC AGENT; BENZAMIDE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ETHYL 3' CHLORO 6 FLUOROPHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3' CHLORO 6 METHOXY 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3' FLUORO 6 CHLORO 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3' FLUORO 6 METHOXY 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3' METHOXY 6 CHLORO 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3' METHOXY 6 FLUORO 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3',6 DICHLOROPHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3',6 DIFLUORO 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 3',6 DIMETHOXY 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; ETHYL 6 FLUORO 2 PHENYL 4 QUINOLONE 3 CARBOXYLATE; N (4 FLUOROPHENYL)BENZAMIDE; N [1 (3 CHLOROPHENYL) 2,2 DIETHOXYCARBONYLVINYL] N (4 FLUOROPHENYL)AMINE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HYDROPHILICITY; IN VITRO STUDY;

ANTINEOPLASTIC AGENTS; CARBOXYLIC ACIDS; CELL LINE, TUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MITOSIS; QUINOLONES; SPECTROPHOTOMETRY, INFRARED;

EID: 9644266706     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.09.041     Document Type: Article

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