Activation of insulin-like growth factor signaling induces apoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response

Cancer Research

Volumn 67, Issue 17, 2007, Pages 8095-8103

  Endo, Hiroko ^a   Murata, Kohei ^a   Mukai, Mutsuko ^a   Ishikawa, Osamu ^a   Inoue, Masahiro ^a,b  

^a Suita Municipal Hospital   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLOHEXIMIDE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; SHORT HAIRPIN RNA; SOMATOMEDIN; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CASPASES; CELL DEATH; CELL HYPOXIA; CYTOCHROMES C; ENDOPLASMIC RETICULUM; HUMANS; INSULIN; MITOCHONDRIA; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; SIGNAL TRANSDUCTION; SOMATOMEDINS; TRANSCRIPTION FACTOR CHOP; TUMOR CELLS, CULTURED;

EID: 34548590356     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-3389     Document Type: Article

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