β-Arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease

Nature Medicine

Volumn 19, Issue 1, 2013, Pages 44-49

  Thathiah, Amantha ^a,b   Horré, Katrien ^a,b   Snellinx, An ^a,b   Vandewyer, Elke ^a,b   Huang, Yunhong ^a,b   Ciesielska, Marta ^a,b   De Kloe, Gerdien ^a,c   Munck, Sebastian ^a,b   De Strooper, Bart ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR; GAMMA SECRETASE; BETA ARRESTIN; GPR3 PROTEIN, MOUSE; RETINA S ANTIGEN; SECRETASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MODEL; ENDOCYTOSIS; ENTORHINAL CORTEX; ENZYME ACTIVITY; GENE DELETION; GENE SILENCING; HIPPOCAMPUS; MEMBRANE; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SUBUNIT; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CELL STRAIN HEK293; CHO CELL; GENETICS; HAMSTER; HELA CELL; HUMAN; METABOLISM; MOUSE MUTANT;

MUS; MUS MUSCULUS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ARRESTINS; CELL LINE; CHO CELLS; CRICETINAE; HEK293 CELLS; HELA CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84872072831     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3023     Document Type: Article

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