Stereoselective synthesis of photoreactive peptidomimetic γ-secretase inhibitors

Journal of Organic Chemistry

Volumn 69, Issue 21, 2004, Pages 7344-7347

  Chun, Jiong ^a   Yin, Ye Ingrid ^a   Yang, Guangli ^a   Tarassishin, Leonid ^a   Li, Yue Ming ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; HYDROGENATION; PHOTOREACTIVITY; SYNTHESIS (CHEMICAL);

BENZOPHENONE; PLASMA MEMBRANES; STEREOSELECTIVE METHODS;

AROMATIC COMPOUNDS;

BENZOPHENONE; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; L 685458; LACTONE; PLATINUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL MEMBRANE; DRUG POTENCY; DRUG SYNTHESIS; ELIMINATION REACTION; ENZYME ACTIVITY; HYDROGENATION; PHOTOREACTIVITY; STEREOCHEMISTRY;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CARBAMATES; CELL MEMBRANE; DIPEPTIDES; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; PEPTIDE FRAGMENTS; PHOTOCHEMISTRY; STEREOISOMERISM;

EID: 5444256890     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0486948     Document Type: Article

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