Involvement of oxidative stress in suppression of insulin biosynthesis under diabetic conditions

International Journal of Molecular Sciences

Volumn 13, Issue 10, 2012, Pages 13680-13690

  Kaneto, Hideaki ^a   Matsuoka, Taka aki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Glucose toxicity; Pancreatic cells; Type 2 diabetes

Indexed keywords

GLUCOSE; INSULIN; JANUS KINASE; MESSENGER RNA; PROTEIN C JUN; PROTEIN KINASE B; TRANSCRIPTION FACTOR MAFA; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

BINDING AFFINITY; BINDING SITE; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL FATE; DIABETES MELLITUS; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; DRUG EFFECTS; HUMAN; METABOLISM; PATHOLOGY;

DIABETES MELLITUS, TYPE 2; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS;

EID: 84870671396     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131013680     Document Type: Review

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