-
2
-
-
33646676272
-
Clinical practice. Acute pancreatitis
-
Whitcomb D.C. Clinical practice. Acute pancreatitis. N Engl J Med 2006;354:2142-2150
-
(2006)
N Engl J Med
, vol.354
, pp. 2142-2150
-
-
Whitcomb, D.C.1
-
3
-
-
34247197621
-
Chronic Pancreatitis: Challenges and Advances in Pathogenesis, Genetics, Diagnosis, and Therapy
-
DOI 10.1053/j.gastro.2007.03.001, PII S0016508507004957
-
Witt H., Apte M.V., Keim V., et al. Chronic pancreatitis: Challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology 2007;132:1557-1573 (Pubitemid 46627604)
-
(2007)
Gastroenterology
, vol.132
, Issue.4
, pp. 1557-1573
-
-
Witt, H.1
Apte, M.V.2
Keim, V.3
Wilson, J.S.4
-
5
-
-
0002616496
-
Über die Selbstverdauung des menschlichen Pankreas
-
Chiari H. Über die Selbstverdauung des menschlichen Pankreas. Z Heilk 1896;17:69-96.
-
(1896)
Z Heilk
, vol.17
, pp. 69-96
-
-
Chiari, H.1
-
7
-
-
0022651240
-
Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation
-
Rinderknecht H. Activation of pancreatic zymogens. Normal activation, premature intrapancreatic activation, protective mechanisms against inappropriate activation. Dig Dis Sci 1986;31:314-321 (Pubitemid 16123978)
-
(1986)
Digestive Diseases and Sciences
, vol.31
, Issue.3
, pp. 314-321
-
-
Rinderknecht, H.1
-
8
-
-
10144246566
-
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
-
DOI 10.1038/ng1096-141
-
Whitcomb D.C., Gorry M.C., Preston R.A., et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141-145 (Pubitemid 26338792)
-
(1996)
Nature Genetics
, vol.14
, Issue.2
, pp. 141-145
-
-
Whitcomb, D.C.1
Gorry, M.C.2
Preston, R.A.3
Furey, W.4
Sossenheimer, M.J.5
Ulrich, C.D.6
Martin, S.P.7
Gates Jr., L.K.8
Amann, S.T.9
Toskes, P.P.10
Liddle, R.11
McGrath, K.12
Uomo, G.13
Post, J.C.14
Ehrlich, G.D.15
-
9
-
-
0030813082
-
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis
-
DOI 10.1053/gast.1997.v113.pm9322498
-
Gorry M.C., Gabbaizedeh D., Furey W., et al. Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology 1997;113:1063-1068 (Pubitemid 27418957)
-
(1997)
Gastroenterology
, vol.113
, Issue.4
, pp. 1063-1068
-
-
Gorry, M.C.1
Gabbaizedeh, D.2
Furey, W.3
Gates Jr., L.K.4
Preston, R.A.5
Aston, C.E.6
Zhang, Y.7
Ulrich, C.8
Ehrlich, G.D.9
Whitcomb, D.C.10
-
10
-
-
0040624999
-
Trypsinogen stabilization by mutation Arg117→His: A unifying pathomechanism for hereditary pancreatitis?
-
DOI 10.1006/bbrc.1999.1565
-
Sahin-Toth M., Graf L., Toth M. Trypsinogen stabilization by mutation Arg117 → His: A unifying pathomechanism for hereditary pancreatitis? Biochem Biophys Res Commun 1999;264:505-508 (Pubitemid 29516116)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.264
, Issue.2
, pp. 505-508
-
-
Sahin-Toth, M.1
Graf, L.2
Toth, M.3
-
11
-
-
0040625000
-
Hereditary pancreatitis-associated mutation asn(21) → ile stabilizes rat trypsinogen in vitro
-
Sahin-Toth M. Hereditary pancreatitis-associated mutation asn(21) → ile stabilizes rat trypsinogen in vitro. J Biol Chem 1999;274:29699-29704
-
(1999)
J Biol Chem
, vol.274
, pp. 29699-29704
-
-
Sahin-Toth, M.1
-
12
-
-
33747010658
-
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
-
DOI 10.1002/humu.20343
-
Teich N., Rosendahl J., Toth M., et al. Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum Mutat 2006;27:721-730 (Pubitemid 44205064)
-
(2006)
Human Mutation
, vol.27
, Issue.8
, pp. 721-730
-
-
Teich, N.1
Rosendahl, J.2
Toth, M.3
Mossner, J.4
Sahin-Toth, M.5
-
13
-
-
0034039578
-
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis
-
DOI 10.1038/76088
-
Witt H., Luck W., Hennies H.C., et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000;25:213-216 (Pubitemid 30394996)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 213-216
-
-
Witt, H.1
Luck, W.2
Hennies, H.C.3
Classen, M.4
Kage, A.5
Lass, U.6
Landt, O.7
Becker, M.8
-
14
-
-
34948901262
-
Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation
-
DOI 10.1136/gut.2006.115725
-
Kiraly O., Wartmann T., Sahin-Toth M. Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation. Gut 2007;56:1433-1438 (Pubitemid 47517840)
-
(2007)
Gut
, vol.56
, Issue.10
, pp. 1433-1438
-
-
Kiraly, O.1
Wartmann, T.2
Sahin-Toth, M.3
-
16
-
-
0031913740
-
Subcellular kinetics of early trypsinogen activation in acute rodent pancreatitis
-
Mithofer K., Fernandez-del Castillo C., Rattner D., et al. Subcellular kinetics of early trypsinogen activation in acute rodent pancreatitis. Am J Physiol 1998;274:G71-G79
-
(1998)
Am J Physiol
, vol.274
-
-
Mithofer, K.1
Fernandez-del Castillo, C.2
Rattner, D.3
-
17
-
-
0031867966
-
Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats
-
Hofbauer B., Saluja A.K., Lerch M.M., et al. Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol 1998;275:G352-G362
-
(1998)
Am J Physiol
, vol.275
-
-
Hofbauer, B.1
Saluja, A.K.2
Lerch, M.M.3
-
18
-
-
0036007501
-
NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response
-
Chen X., Ji B., Han B., et al. NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response. Gastroenterology 2002;122:448-457 (Pubitemid 34116996)
-
(2002)
Gastroenterology
, vol.122
, Issue.2
, pp. 448-457
-
-
Chen, X.1
Ji, B.2
Han, B.3
Ernst, S.A.4
Simeone, D.5
Logsdon, C.D.6
-
19
-
-
34249887978
-
Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo
-
DOI 10.1172/JCI30876
-
Baumann B., Wagner M., Aleksic T., et al. Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. J Clin Invest 2007;117:1502-1513 (Pubitemid 46871335)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1502-1513
-
-
Baumann, B.1
Wagner, M.2
Aleksic, T.3
Von Wichert, G.4
Weber, C.K.5
Adler, G.6
Wirth, T.7
-
20
-
-
34249879045
-
Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis
-
DOI 10.1172/JCI29882
-
Algul H., Treiber M., Lesina M., et al. Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. J Clin Invest 2007;117:1490-1501 (Pubitemid 46871334)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1490-1501
-
-
Algul, H.1
Treiber, M.2
Lesina, M.3
Nakhai, H.4
Saur, D.5
Geisler, F.6
Pfeifer, A.7
Paxian, S.8
Schmid, R.M.9
-
21
-
-
0036085976
-
Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation
-
Halangk W., Kruger B., Ruthenburger M., et al. Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation. Am J Physiol Gastrointest Liver Physiol 2002;282:G367-G374 (Pubitemid 34651694)
-
(2002)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.282
, Issue.2
-
-
Halangk, W.1
Kruger, B.2
Ruthenburger, M.3
Sturzebecher, J.4
Albrecht, E.5
Lippert, H.6
Lerch, M.M.7
-
22
-
-
67650513305
-
Intracellular trypsin induces pancreatic acinar cell death but not NF-kappaB activation
-
Ji B., Gaiser S., Chen X., et al. Intracellular trypsin induces pancreatic acinar cell death but not NF-kappaB activation. J Biol Chem 2009;284:17488-17498
-
(2009)
J Biol Chem
, vol.284
, pp. 17488-17498
-
-
Ji, B.1
Gaiser, S.2
Chen, X.3
-
23
-
-
52049101359
-
Robust acinar cell transgene expression of CreErT via BAC recombineering
-
Ji B., Song J., Tsou L., et al. Robust acinar cell transgene expression of CreErT via BAC recombineering. Genesis 2008;46:390-395
-
(2008)
Genesis
, vol.46
, pp. 390-395
-
-
Ji, B.1
Song, J.2
Tsou, L.3
-
24
-
-
0038029879
-
Human anionic trypsinogen. Properties of autocatalytic activation and degradation and implications in pancreatic diseases
-
DOI 10.1046/j.1432-1033.2003.03581.x
-
Kukor Z., Toth M., Sahin-Toth M. Human anionic trypsinogen: Properties of autocatalytic activation and degradation and implications in pancreatic diseases. Eur J Biochem 2003;270:2047-2058 (Pubitemid 36560827)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.9
, pp. 2047-2058
-
-
Kukor, Z.1
Toth, M.2
Sahin-Toth, M.3
-
26
-
-
21444454735
-
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration
-
DOI 10.1038/nmeth762
-
Buch T., Heppner F.L., Tertilt C., et al. A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods 2005;2:419-426 (Pubitemid 40916560)
-
(2005)
Nature Methods
, vol.2
, Issue.6
, pp. 419-426
-
-
Buch, T.1
Heppner, F.L.2
Tertilt, C.3
Heinen, T.J.A.J.4
Kremer, M.5
Wunderlich, F.T.6
Jung, S.7
Waisman, A.8
-
27
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
DOI 10.1101/gad.1199904
-
Zong W.X., Ditsworth D., Bauer D.E., et al. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 2004;18:1272-1282 (Pubitemid 38720595)
-
(2004)
Genes and Development
, vol.18
, Issue.11
, pp. 1272-1282
-
-
Zong, W.-X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.-Q.4
Thompson, C.B.5
-
28
-
-
0032246276
-
Early NF-kappaB activation is associated with hormone-induced pancreatitis
-
Gukovsky I., Gukovskaya A.S., Blinman T.A., et al. Early NF-kappaB activation is associated with hormone-induced pancreatitis. Am J Physiol 1998;275:G1402-G1414
-
(1998)
Am J Physiol
, vol.275
-
-
Gukovsky, I.1
Gukovskaya, A.S.2
Blinman, T.A.3
-
29
-
-
0011770646
-
CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells
-
Han B., Ji B., Logsdon C.D. CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells. Am J Physiol Cell Physiol 2001;280:C465-C472
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Han, B.1
Ji, B.2
Logsdon, C.D.3
-
30
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W., Lerch M.M., Brandt-Nedelev B., et al. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000;106:773-781
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
-
31
-
-
0037077262
-
Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis
-
DOI 10.1074/jbc.M200878200
-
Kukor Z., Mayerle J., Kruger B., et al. Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis. J Biol Chem 2002;277:21389-21396 (Pubitemid 34952279)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.24
, pp. 21389-21396
-
-
Kukor, Z.1
Mayerle, J.2
Kruger, B.3
Toth, M.4
Steed, P.M.5
Halangk, W.6
Lerch, M.M.7
Sahin-Toth, M.8
-
34
-
-
22144457412
-
Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells
-
DOI 10.1016/j.bbrc.2005.06.148, PII S0006291X05013835
-
Gaiser S., Ahler A., Gundling F., et al. Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells. Biochem Biophys Res Commun 2005;334:721-728 (Pubitemid 40982426)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.2
, pp. 721-728
-
-
Gaiser, S.1
Ahler, A.2
Gundling, F.3
Kruse, M.-L.4
Savkovic, V.5
Selig, L.6
Teich, N.7
Tomasini, R.8
Dagorn, J.-C.9
Mossner, J.10
Keim, V.11
Bodeker, H.12
-
35
-
-
70450248392
-
Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death
-
Kereszturi E., Sahin-Toth M. Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death. J Biol Chem 2009;284:33392-33399
-
(2009)
J Biol Chem
, vol.284
, pp. 33392-33399
-
-
Kereszturi, E.1
Sahin-Toth, M.2
-
36
-
-
4944257738
-
The continuing challenge of early mortality in acute pancreatitis
-
DOI 10.1002/bjs.4750
-
McKay C.J., Imrie C.W. The continuing challenge of early mortality in acute pancreatitis. Br J Surg 2004;91:1243-1244 (Pubitemid 39331447)
-
(2004)
British Journal of Surgery
, vol.91
, Issue.10
, pp. 1243-1244
-
-
McKay, C.J.1
Imrie, C.W.2
-
37
-
-
0028783295
-
Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
-
Kaiser A.M., Saluja A.K., Sengupta A., et al. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol 1995;269:C1295-C1304
-
(1995)
Am J Physiol
, vol.269
-
-
Kaiser, A.M.1
Saluja, A.K.2
Sengupta, A.3
-
38
-
-
33645640921
-
Cell death in pancreatitis: Caspases protect from necrotizing pancreatitis
-
DOI 10.1074/jbc.M511276200
-
Mareninova O.A., Sung K.F., Hong P., et al. Cell death in pancreatitis: Caspases protect from necrotizing pancreatitis. J Biol Chem 2006;281:3370-3381 (Pubitemid 43845951)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.6
, pp. 3370-3381
-
-
Mareninova, O.A.1
Sung, K.-F.2
Hong, P.3
Lugea, A.4
Pandol, S.J.5
Gukovsky, I.6
Gukovskaya, A.S.7
-
39
-
-
0030025675
-
Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat
-
DOI 10.1053/gast.1996.v110.pm8608898
-
Gukovskaya A.S., Perkins P., Zaninovic V., et al. Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology 1996;110:875-884 (Pubitemid 26071855)
-
(1996)
Gastroenterology
, vol.110
, Issue.3
, pp. 875-884
-
-
Gukovskaya, A.S.1
Perkins, P.2
Zaninovic, V.3
Sandoval, D.4
Rutherford, R.5
Fitzsimmons, T.6
Pandol, S.J.7
Poucell-Hatton, S.8
-
40
-
-
0031869923
-
Induction of apoptosis with an extract of Artemisia asiatica attenuates the severity of cerulein-induced pancreatitis in rats
-
Hahm K.B., Kim J.H., You B.M., et al. Induction of apoptosis with an extract of Artemisia asiatica attenuates the severity of cerulein-induced pancreatitis in rats. Pancreas 1998;17:153-157
-
(1998)
Pancreas
, vol.17
, pp. 153-157
-
-
Hahm, K.B.1
Kim, J.H.2
You, B.M.3
-
42
-
-
0028295094
-
Progression of alcoholic acute to chronic pancreatitis
-
Ammann R.W., Muellhaupt B. Progression of alcoholic acute to chronic pancreatitis. Gut 1994;35:552-556 (Pubitemid 24131256)
-
(1994)
Gut
, vol.35
, Issue.4
, pp. 552-556
-
-
Ammann, R.W.1
Muellhaupt, B.2
-
43
-
-
0026595479
-
The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis
-
Kloppel G., Maillet B. The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis. Virchows Arch A Pathol Anat Histopathol 1992;420:1-4.
-
(1992)
Virchows Arch A Pathol Anat Histopathol
, vol.420
, pp. 1-4
-
-
Kloppel, G.1
Maillet, B.2
-
44
-
-
33846506591
-
Focal fatty replacement of the pancreas: Usefulness of chemical shift MRI
-
DOI 10.2214/AJR.05.1095
-
Kim H.J., Byun J.H., Park S.H., et al. Focal fatty replacement of the pancreas: Usefulness of chemical shift MRI. AJR Am J Roentgenol 2007;188:429-432 (Pubitemid 46167745)
-
(2007)
American Journal of Roentgenology
, vol.188
, Issue.2
, pp. 429-432
-
-
Kim, H.J.1
Byun, J.H.2
Park, S.H.3
Shin, Y.M.4
Kim, P.N.5
Ha, H.K.6
Lee, M.-G.7
-
45
-
-
10044284417
-
Inhibition of transforming growth factor beta decreases pancreatic fibrosis and protects the pancreas against chronic injury in mice
-
DOI 10.1038/labinvest.3700191
-
Nagashio Y., Ueno H., Imamura M., et al. Inhibition of transforming growth factor beta decreases pancreatic fibrosis and protects the pancreas against chronic injury in mice. Lab Invest 2004;84:1610-1618 (Pubitemid 39600568)
-
(2004)
Laboratory Investigation
, vol.84
, Issue.12
, pp. 1610-1618
-
-
Nagashio, Y.1
Ueno, H.2
Imamura, M.3
Asaumi, H.4
Watanabe, S.5
Yamaguchi, T.6
Taguchi, M.7
Tashiro, M.8
Otsuki, M.9
-
46
-
-
33845664588
-
A Mouse Model of Hereditary Pancreatitis Generated by Transgenic Expression of R122H Trypsinogen
-
DOI 10.1053/j.gastro.2006.09.049, PII S0016508506022177
-
Archer H., Jura N., Keller J., et al. A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology 2006;131:1844-1855 (Pubitemid 44958518)
-
(2006)
Gastroenterology
, vol.131
, Issue.6
, pp. 1844-1855
-
-
Archer, H.1
Jura, N.2
Keller, J.3
Jacobson, M.4
Bar-Sagi, D.5
-
47
-
-
33751233226
-
Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen
-
Selig L., Sack U., Gaiser S., et al. Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen. BMC Gastroenterol 2006;6:30.
-
(2006)
BMC Gastroenterol
, vol.6
, pp. 30
-
-
Selig, L.1
Sack, U.2
Gaiser, S.3
-
48
-
-
69249148349
-
Ras activity levels control the development of pancreatic diseases
-
Ji B., Tsou L., Wang H., et al. Ras activity levels control the development of pancreatic diseases. Gastroenterology 2009;137:1072-1082
-
(2009)
Gastroenterology
, vol.137
, pp. 1072-1082
-
-
Ji, B.1
Tsou, L.2
Wang, H.3
|