Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3-deficient mice and restores a normal pancreatic phenotype

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 298, Issue 4, 2010, Pages

  Romac, Joelle M J ^a   Ohmuraya, Masaki ^c   Bittner, Cathy ^a   Majeed, M Faraz ^a   Vigna, Steven R ^a   Que, Jianwen ^a   Fee, Brian E ^a   Wartmann, Thomas ^d   Yamamura, Ken Ichi ^c   Liddle, Rodger A ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

^c KUMAMOTO UNIVERSITY   (Japan)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Autophagy; Pancreatitis; PSTI I

Indexed keywords

PANCREATIC SECRETORY TRYPSIN INHIBITOR 1; SERINE PROTEASE INHIBITOR KAZAL TYPE 3; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE EXPRESSION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; WILD TYPE;

AMINO ACID SEQUENCE; AMYLASES; ANIMALS; BODY SIZE; CAERULEIN; FEMALE; GLYCOPROTEINS; HETEROZYGOTE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; ORGAN SIZE; PANCREAS; PANCREAS, EXOCRINE; PANCREATITIS; PROSTATIC SECRETORY PROTEINS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SURVIVAL RATE; TRANSGENES; TRYPSIN;

EID: 77950287997     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00431.2009     Document Type: Article

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