Cathepsin L Inactivates Human Trypsinogen, Whereas Cathepsin L-Deletion Reduces the Severity of Pancreatitis in Mice

Gastroenterology

Volumn 138, Issue 2, 2010, Pages 726-737

  Wartmann, Thomas ^a   Mayerle, Julia ^b   Kähne, Thilo ^a   Sahin Tóth, Miklós ^c   Ruthenbürger, Manuel ^b   Matthias, Rainer ^a   Kruse, Anne ^b   Reinheckel, Thomas ^d   Peters, Christoph ^d   Weiss, F Ulrich ^b   Sendler, Matthias ^b   Lippert, Hans ^a   Schulz, Hans Ulrich ^a   Aghdassi, Ali ^b   Dummer, Annegret ^b   Teller, Steffen ^b   Halangk, Walter ^a   Lerch, Markus M ^b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c BOSTON UNIVERSITY   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN L; CERULETIDE; RECOMBINANT ENZYME; TAUROCHOLIC ACID; TRYPSINOGEN; TRYPSINOGEN ACTIVATION PEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRON MICROSCOPY; EMBRYO; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LYSOSOME; MOUSE; NONHUMAN; PANCREAS JUICE; PANCREATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SECRETORY VESICLE;

EID: 75149137394     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.10.048     Document Type: Article

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