-
1
-
-
0002616496
-
Über die Selbstverdauung des menschlichen Pankreas
-
Chiari H. Über die Selbstverdauung des menschlichen Pankreas. Zeitschrift für Heilkunde 1896;17:69-96.
-
(1896)
Zeitschrift für Heilkunde
, vol.17
, pp. 69-96
-
-
Chiari, H.1
-
2
-
-
0031913740
-
Subcellular kinetics of early trypsinogen activation in acute rodent pancreatitis
-
Mithofer K., Fernandez-del Castillo C., Rattner D., et al. Subcellular kinetics of early trypsinogen activation in acute rodent pancreatitis. Am J Physiol 1998;274:G71-G79
-
(1998)
Am J Physiol
, vol.274
-
-
Mithofer, K.1
Fernandez-del Castillo, C.2
Rattner, D.3
-
3
-
-
0031867966
-
Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats
-
Hofbauer B., Saluja A.K., Lerch M.M., et al. Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol 1998;275: G352-G362
-
(1998)
Am J Physiol
, vol.275
-
-
Hofbauer, B.1
Saluja, A.K.2
Lerch, M.M.3
-
4
-
-
0032957613
-
Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini
-
Saluja A.K., Bhagat L., Lee H.S., et al. Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Am J Physiol 1999;276:G835-G842 (Pubitemid 29214095)
-
(1999)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.276
, Issue.4
-
-
Saluja, A.K.1
Bhagat, L.2
Lee, H.S.3
Bhatia, M.4
Frossard, J.L.5
Steer, M.L.6
-
5
-
-
0034077468
-
Early trypsinogen activation in acute pancreatitis
-
Lerch M.M., Gorelick F.S. Early trypsinogen activation in acute pancreatitis. Med Clin North Am 2000;84:549-563, viii. (Pubitemid 30346151)
-
(2000)
Medical Clinics of North America
, vol.84
, Issue.3
, pp. 549-563
-
-
Lerch, M.M.1
Gorelick, F.S.2
-
6
-
-
0023484519
-
Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis
-
Saluja A., Hashimoto S., Saluja M., et al. Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol 1987;253:G508-G516
-
(1987)
Am J Physiol
, vol.253
-
-
Saluja, A.1
Hashimoto, S.2
Saluja, M.3
-
7
-
-
0024416027
-
Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization
-
Saluja A., Saluja M., Villa A., et al. Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization. J Clin Invest 1989;84:1260-1266 (Pubitemid 19247599)
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.4
, pp. 1260-1266
-
-
Saluja, A.1
Saluja, M.2
Villa, A.3
Leli, U.4
Rutledge, P.5
Meldolesi, J.6
Steer, M.7
-
8
-
-
46249114022
-
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells
-
DOI 10.1083/jcb.200712156
-
Hashimoto D., Ohmuraya M., Hirota M., et al. Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J Cell Biol 2008;181:1065-1072 (Pubitemid 351915482)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.7
, pp. 1065-1072
-
-
Hashimoto, D.1
Ohmuraya, M.2
Hirota, M.3
Yamamoto, A.4
Suyama, K.5
Ida, S.6
Okumura, Y.7
Takahashi, E.8
Kido, H.9
Araki, K.10
Baba, H.11
Mizushima, N.12
Yamamura, K.-I.13
-
9
-
-
70449426665
-
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
-
Mareninova O.A., Hermann K., French S.W., et al. Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest 2009;119:3340-3355
-
(2009)
J Clin Invest
, vol.119
, pp. 3340-3355
-
-
Mareninova, O.A.1
Hermann, K.2
French, S.W.3
-
10
-
-
0030959639
-
Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B
-
DOI 10.1016/S0016-5085(97)70108-2
-
Saluja A.K., Donovan E.A., Yamanaka K., et al. Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B. Gastroenterology 1997;113:304-310 (Pubitemid 27281787)
-
(1997)
Gastroenterology
, vol.113
, Issue.1
, pp. 304-310
-
-
Saluja, A.K.1
Donovan, E.A.2
Yamanaka, K.3
Yamaguchi, Y.4
Hofbauer, B.5
Steer, M.L.6
-
11
-
-
0036720909
-
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity
-
Van Acker G.J., Saluja A.K., Bhagat L., et al. Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity. Am J Physiol Gastrointest Liver Physiol 2002;283:G794-G800 (Pubitemid 34920370)
-
(2002)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.283
, Issue.3
-
-
Van Acker, G.J.D.1
Saluja, A.K.2
Bhagat, L.3
Singh, V.P.4
Song, A.M.5
Steer, M.L.6
-
13
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W., Lerch M.M., Brandt-Nedelev B., et al. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000;106:773-781
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
-
14
-
-
0022462341
-
Human acute pancreatitis: Its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells
-
Kloppel G., Dreyer T., Willemer S., et al. Human acute pancreatitis: Its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells. Virchows Arch A Pathol Anat Histopathol 1986;409:791-803. (Pubitemid 16044947)
-
(1986)
Virchows Archiv - A Pathological Anatomy and Histopathology
, vol.409
, Issue.6
, pp. 791-803
-
-
Kloppel, G.1
Dreyer, T.2
Willemer, S.3
-
15
-
-
0024403314
-
Immunocytochemical and morphometric analysis of acinar zymogen granules in human acute pancreatitis
-
Willemer S., Kloppel G., Kern H.F., et al. Immunocytochemical and morphometric analysis of acinar zymogen granules in human acute pancreatitis. Virchows Arch A Pathol Anat Histopathol 1989;415:115-123 (Pubitemid 19170559)
-
(1989)
Virchows Archiv - A Pathological Anatomy and Histopathology
, vol.415
, Issue.2
, pp. 115-123
-
-
Willemer, S.1
Kloppel, G.2
Kern, H.F.3
Adler, G.4
-
16
-
-
80052570335
-
Deletion of trypsinogen T7 significantly decreases trypsin activation pancreatic necrosis in caerulein induced pancreatitis
-
Dawra R.K., Dudeja V., Saluja A.K. Deletion of trypsinogen T7 significantly decreases trypsin activation pancreatic necrosis in caerulein induced pancreatitis. Pancreas 2009;38:992-993
-
(2009)
Pancreas
, vol.38
, pp. 992-993
-
-
Dawra, R.K.1
Dudeja, V.2
Saluja, A.K.3
-
17
-
-
67650513305
-
Intracellular trypsin induces pancreatic acinar cell death but not NF-kappa B activation
-
Ji B., Gaiser S., Chen X., et al. Intracellular trypsin induces pancreatic acinar cell death but not NF-kappa B activation. J Biol Chem 2009;284:17488-17498
-
(2009)
J Biol Chem
, vol.284
, pp. 17488-17498
-
-
Ji, B.1
Gaiser, S.2
Chen, X.3
-
18
-
-
22144457412
-
Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells
-
DOI 10.1016/j.bbrc.2005.06.148, PII S0006291X05013835
-
Gaiser S., Ahler A., Gundling F., et al. Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells. Biochem Biophys Res Commun 2005;334:721-728 (Pubitemid 40982426)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.2
, pp. 721-728
-
-
Gaiser, S.1
Ahler, A.2
Gundling, F.3
Kruse, M.-L.4
Savkovic, V.5
Selig, L.6
Teich, N.7
Tomasini, R.8
Dagorn, J.-C.9
Mossner, J.10
Keim, V.11
Bodeker, H.12
-
19
-
-
70450248392
-
Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death
-
Kereszturi E., Sahin-Toth M. Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death. J Biol Chem 2009;284:33392-33399
-
(2009)
J Biol Chem
, vol.284
, pp. 33392-33399
-
-
Kereszturi, E.1
Sahin-Toth, M.2
-
20
-
-
80052586196
-
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis
-
Gaiser S., Daniluk J., Liu Y., et al. Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis. Gut 2011;60:1379-1388
-
(2011)
Gut
, vol.60
, pp. 1379-1388
-
-
Gaiser, S.1
Daniluk, J.2
Liu, Y.3
-
21
-
-
10144246566
-
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
-
DOI 10.1038/ng1096-141
-
Whitcomb D.C., Gorry M.C., Preston R.A., et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141-145 (Pubitemid 26338792)
-
(1996)
Nature Genetics
, vol.14
, Issue.2
, pp. 141-145
-
-
Whitcomb, D.C.1
Gorry, M.C.2
Preston, R.A.3
Furey, W.4
Sossenheimer, M.J.5
Ulrich, C.D.6
Martin, S.P.7
Gates Jr., L.K.8
Amann, S.T.9
Toskes, P.P.10
Liddle, R.11
McGrath, K.12
Uomo, G.13
Post, J.C.14
Ehrlich, G.D.15
-
22
-
-
0034039578
-
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis
-
DOI 10.1038/76088
-
Witt H., Luck W., Hennies H.C., et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000;25:213-216 (Pubitemid 30394996)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 213-216
-
-
Witt, H.1
Luck, W.2
Hennies, H.C.3
Classen, M.4
Kage, A.5
Lass, U.6
Landt, O.7
Becker, M.8
-
23
-
-
77951920963
-
Genetic aspects of pancreatitis
-
Whitcomb D.C. Genetic aspects of pancreatitis. Annu Rev Med 2010;61:413-424
-
(2010)
Annu Rev Med
, vol.61
, pp. 413-424
-
-
Whitcomb, D.C.1
-
24
-
-
70350225542
-
Chronic pancreatitis: Genetics and pathogenesis
-
Chen J.M., Ferec C. Chronic pancreatitis: Genetics and pathogenesis. Annu Rev Genomics Hum Genet 2009;10:63-87.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 63-87
-
-
Chen, J.M.1
Ferec, C.2
-
25
-
-
33747010658
-
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
-
DOI 10.1002/humu.20343
-
Teich N., Rosendahl J., Toth M., et al. Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum Mutat 2006;27:721-730 (Pubitemid 44205064)
-
(2006)
Human Mutation
, vol.27
, Issue.8
, pp. 721-730
-
-
Teich, N.1
Rosendahl, J.2
Toth, M.3
Mossner, J.4
Sahin-Toth, M.5
-
26
-
-
33745227350
-
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis
-
DOI 10.1038/ng1797, PII N1797
-
Witt H., Sahin-Toth M., Landt O., et al. A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis. Nat Genet 2006;38:668-673 (Pubitemid 43927309)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 668-673
-
-
Witt, H.1
Sahin-Toth, M.2
Landt, O.3
Chen, J.-M.4
Kahne, T.5
Drenth, J.P.H.6
Kukor, Z.7
Szepessy, E.8
Halangk, W.9
Dahm, S.10
Rohde, K.11
Schulz, H.-U.12
Le, M.C.13
Akar, N.14
Ammann, R.W.15
Truninger, K.16
Bargetzi, M.17
Bhatia, E.18
Castellani, C.19
Cavestro, G.M.20
Cerny, M.21
Destro-Bisol, G.22
Spedini, G.23
Eiberg, H.24
Jansen, J.B.M.J.25
Koudova, M.26
Rausova, E.27
Macek Jr., M.28
Malats, N.29
Real, F.X.30
Menzel, H.-J.31
Moral, P.32
Galavotti, R.33
Pignatti, P.F.34
Rickards, O.35
Spicak, J.36
Zarnescu, N.O.37
Bock, W.38
Gress, T.M.39
Friess, H.40
Ockenga, J.41
Schmidt, H.42
Pfutzer, R.43
Lohr, M.44
Simon, P.45
Weiss, F.U.46
Lerch, M.M.47
Teich, N.48
Keim, V.49
Berg, T.50
Wiedenmann, B.51
Luck, W.52
Groneberg, D.A.53
Becker, M.54
Keil, T.55
Kage, A.56
Bernardova, J.57
Braun, M.58
Guldner, C.59
Halangk, J.60
Rosendahl, J.61
Witt, U.62
Treiber, M.63
Nickel, R.64
Ferec, C.65
more..
-
27
-
-
0038029879
-
Human anionic trypsinogen. Properties of autocatalytic activation and degradation and implications in pancreatic diseases
-
DOI 10.1046/j.1432-1033.2003.03581.x
-
Kukor Z., Toth M., Sahin-Toth M. Human anionic trypsinogen: Properties of autocatalytic activation and degradation and implications in pancreatic diseases. Eur J Biochem 2003;270:2047-2058 (Pubitemid 36560827)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.9
, pp. 2047-2058
-
-
Kukor, Z.1
Toth, M.2
Sahin-Toth, M.3
|