PfCRT and its role in antimalarial drug resistance

Trends in Parasitology

Volumn 28, Issue 11, 2012, Pages 504-514

  Ecker, Andrea ^a   Lehane, Adele M ^a,b   Clain, Jérôme ^a,c   Fidock, David A ^a  

^a Columbia University ^*  (United States)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

Author keywords

Drug resistance; Haplotypes; Heme detoxification; Malaria; PfCRT; Plasmodium falciparum; Selective sweep; Transmission

Indexed keywords

ARTEMISININ; CHLOROQUINE;

ANTIMALARIAL DRUG RESISTANCE; CELL CULTURE; DICTYOSTELIUM DISCOIDEUM; DRUG MECHANISM; EPISTASIS; GAMETOCYTE; GENETIC ASSOCIATION; HAPLOTYPE; HOST SUSCEPTIBILITY; HUMAN; MULTIDRUG RESISTANCE; MUTANT; MUTATION; NONHUMAN; PARASITE TRANSMISSION; PHENOTYPE; PHYLOGENY; PICHIA PASTORIS; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PROTEIN SYNTHESIS; REVIEW; SCREENING; TREATMENT FAILURE; WILD TYPE;

ANTIMALARIALS; DRUG RESISTANCE; HUMANS; MALARIA, FALCIPARUM; MEMBRANE TRANSPORT PROTEINS; MUTATION; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 84867843026     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2012.08.002     Document Type: Review

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