In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria

Acta Tropica

Volumn 120, Issue 3, 2011, Pages 224-230

  Folarin, O A ^a   Bustamante, C ^b   Gbotosho, G O ^a   Sowunmi, A ^a   Zalis, M G ^b   Oduola, A M J ^c   Happi, C T ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Amodiaquine; Mutation; Pfcrt; Pfmdr1; Plasmodium falciparum; Resistance

Indexed keywords

AMODIAQUINE;

DRUG; EPIDEMIOLOGY; GENE; MALARIA; MOLECULAR ANALYSIS; MUTATION; PARASITE RESISTANCE; POLYMORPHISM; PROTOZOAN;

ALLELE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE SURVEILLANCE; DNA POLYMORPHISM; GENE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; HAPLOTYPE; HUMAN; IN VITRO STUDY; INFANT; MAJOR CLINICAL STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR EPIDEMIOLOGY; MOLECULAR GENETICS; MUTANT; NIGERIA; NONHUMAN; PARASITE ISOLATION; PFCRT GENE; PFMDR1 GENE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; REFERENCE VALUE; SCHIZONT; WILD TYPE;

ALLELES; AMODIAQUINE; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; DNA, PROTOZOAN; FEMALE; HAPLOTYPES; HUMANS; INFANT; MALE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION, MISSENSE; NIGERIA; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; PROTOZOAN PROTEINS;

NIGERIA;

ARTESUNATE; PLASMODIUM FALCIPARUM;

EID: 80054871472     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2011.08.013     Document Type: Article

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