The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-β-synthase: Studies in hepatocytes

Atherosclerosis

Volumn 158, Issue 2, 2001, Pages 297-301

  Dicker Brown, Aliza ^a   Fonseca, Vivian A ^a   Fink, Louis M ^b   Kern, Philip A ^a,c  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Tel: +1 501 2574820 ^*  (United States)

Author keywords

CBS; Homocysteine; Insulin; Insulin resistance; MTHFR

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYSTATHIONINE BETA SYNTHASE; GLUCOSE; HOMOCYSTEINE; INSULIN;

AMINO ACID METABOLISM; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL CULTURE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERINSULINEMIA; IN VITRO STUDY; INSULIN RESISTANCE; KIDNEY; LIVER; LIVER CELL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; CYSTATHIONINE BETA-SYNTHASE; GLUCOSE; HEPATOCYTES; HOMOCYSTEINE; HUMANS; INSULIN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; MICE, INBRED C57BL; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; TUMOR CELLS, CULTURED;

EID: 0034813120     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(01)00442-7     Document Type: Article

References (24)

1. Hyperhomocysteinemia - An emerging and important risk factor for thromboembolic and cardiovascular disease
2. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
3. Homocysteine and atherothrombosis
4. Plasma total homocysteine in healthy subjects: Sex-specific relation with biological traits
5. Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus
6. Hyperhomocysteinemia following a methionine load in patients with non-insulin-dependent diabetes mellitus and macrovascular disease
7. Hyperhomocyst(e)inemia and endothelial dysfunction in IDDM
8. Plasma homocysteine concentrations are regulated by acute hyperinsulinemia in nondiabetic but not type 2 diabetic subjects
9. Effects of a high-fat, sucrose diet on serum insulin and related atherosclerotic risk factors in rats
10. Effects of a high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat
11. Disorders of transsulfuration
12. Transsulfuration in mammals
13. Cystathionine B-synthase (Human)
14. Homocystinuria associated with decreased methylenetetrahydrofolate reductase activity
15. Homocysteine and atherosclerosis
16. Homocysteine and vascular disease
17. Homocyst(e)ine and arterial occlusive diseases
18. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: A population-based study
19. Diabetes in America: Epidemiology and scope of the problem
20. The mystery of diabetes and atherosclerosis: Time for a new plot
21. Role of insulin-resistance in human disease
22. Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat
23. Homocysteine catabolism: Levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease
24. Plasma total homocysteine levels in subjects with hyperinsulinemia