Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells

Journal of Biological Chemistry

Volumn 272, Issue 2, 1997, Pages 1377-1381

  Welham, Melanie J ^a,b   Bone, Heather ^a,b   Levings, Megan ^a   Learmonth, Leslie ^a   Wang, Ling Mei ^c   Leslie, Kevin B ^a   Pierce, Jacalyn H ^c   Schrader, John W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b University of Bath   (United Kingdom)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUTATHIONE TRANSFERASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; INOSITOL PHOSPHATE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 3; INTERLEUKIN 4; TYROSINE;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE RESPONSIVE ELEMENT; GENE EXPRESSION; HEMATOPOIETIC CELL; LYMPHOPOIESIS; MACROPHAGE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AVIAN PROTEINS; CYTOKINES; CYTOSKELETAL PROTEINS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; GRB2 ADAPTOR PROTEIN; HEMATOPOIETIC STEM CELLS; INSULIN; INTERLEUKIN-3; INTERLEUKIN-4; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTES; MICE; MOLECULAR WEIGHT; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SHP1 PROTEIN TYROSINE PHOSPHATASE; TYROSINE;

ANIMALIA; MURINAE;

EID: 0031012544     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.2.1377     Document Type: Article

References (36)

1. Keegan, A. D., Nelms, K., Wang, L-M., Pierce, J. H., and Paul, W. E. (1994) Immunol. Today 15, 423-432
2. Duronio, V., Welham, M., Abraham, S., Dryen, P., and Schrader, J. W. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 1587-1591
3. Satoh, T., Nakafuku, M., Miyajima, A., and Kaziro, Y. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3314-3318
4. Welham, M. J., Duronio, V., and Schrader, J. W. (1994) J. Biol. Chem. 269, 5865-5873
5. Turner, B., Rapp, U., App, H., Greene, M., Dobahi, K., and Reed, J. (1991) Proc. Natl. Acad. Sci. U. S. A. 89, 1227-1231
6. Welham, M. J., Duronio, V., Sanghera, J. S., Pelech, S., and Schrader, J. W. (1992) J. Immunol. 149, 1683-1693
7. Welham, M. J., Duronio, V., Leslie, K. B., Bowtell, D., and Schrader, J. W. (1994) J. Biol Chem. 269, 21165-21176
8. Wang, L.-M., Keegan, A. D., Paul, W. E., Heidaran, M. A., Gutkind, J. S., and Pierce, J. H. (1992) EMBO J. 11, 4899-4908
9. Welham, M. J., Dechert, U., Leslie, K. B., Jirik, F., and Schrader, J. W. (1994) J. Biol. Chem. 269, 23764-23768
10. Gold, M. R., Duronio, V., Saxena, S. P., Schrader, J. W., and Aebersold, R. (1994) J. Biol. Chem. 269, 5403-5412
11. Izuhara, K., and Harada, N. (1993) J. Biol. Chem. 268, 13097-13102
12. Wang, L-W., Keegan, A. D., Li, W., Lienhard, G. E., Pacini, S., Gutkind, J. S., Myers, M. G., Sun, X-J., White, M. F., Aaronson, S. A., Paul, W. E., and Pierce, J. H. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4032-4036
13. Wang, L.-M., Michieli, P., Lie, W.-R., Liu, F., Lee, C.-C., Minty, A., Sun, X.-J., Levine, A., White, M. F., and Pierce, J. P. (1995) Blood 86, 4218-4227
14. Welham, M. J., Learmonth, L., Bone, H., and Schrader, J. W. (1995) J. Biol. Chem. 270, 12286-12296
15. Sun, X. J., Wang, L.-M., Zhang, Y., Yenush, L., Myers, M. G., Jr., Glasheen, E., Lane, W. S., Pierce, J. P., and White, M. F. (1995) Nature 337, 173-177
16. Pawson, T. (1995) Narure 373, 573-580
17. Keegan, A. D., Nelms, K., White, M. F., Wang, L-M., Pierce, J. H., and Paul, W. E. (1994) Cell 76, 811-820
18. Wang, L.-M., Myers, M. G., Jr., Sun, X. J., Aaronson, S. A., White, M. W., and Pierce, J. H. (1993) Science 261, 1591-1594
19. Argetsinger, L. S., Hsu, G. W., Myers, M. G., Jr., Billestrup, N., White, M. F., and Carter-Su, C. (1995) J. Biol Chem. 270, 14685-14692
20. Ridderstrale, M., Degerman, E., and Tornqvist, H. (1994) J. Biol Chem. 270, 3471-3474
21. Souza, S. C., Frick, G. P., Yip, R., Lobo, R. B., Tai, L. R., and Goodman, H. M. (1994) J. Biol. Chem. 269, 30085-30088
22. White, M. F., and Kahn, C. R. (1994) J. Biol. Chem. 269, 1-4
23. Yin, T., Tsang, M. L-S., and Yang, Y-C. 11994) J. Biol. Chem. 269, 26614-26617
24. Johnston, J. A., Wang, L-M., Hanson, E. P., Sun, X-J., White, M. F., Oakes, S. A., Pierce, J. H., and O'Shea, J. J. (1995) J. Biol. Chem. 270, 28527-28530
25. Araki, E., Lipes, M. A., Patti, M.-E., Bruenning, J. C., III, B. H., Johnson, R. S., and Kahn, C. R. (1994) Nature 372, 186-189
26. Tamemoto, H., Kadowaki, T., Tobe, K., Yagi, T., Sakura, H., Hayakawa, T., Terauchi, Y., Ueki, K., Kaburagi, Y., Satoh, S., Sekihara, H., Yoshioka, S., Horikoshi, H., Furuta, Y., Ikawa, Y., Kasuga, M., Yazaki, Y., and Aizawa, S (1994) Nature 372, 182-186
27. Hu-Li, J., Ohara, J., Watson, C., Tsang, W., and Paul, W. E. (1989) J. Immunol. 142, 800-807
28. Watts, J., Welham, M. J., Kalt, L., Schrader, J. W., and Abersold, R. A., (1993) J. Immunol. 151, 6862-6871
29. Andersonn, J., Sjoberg, O., and Moller, G. (1972) Eur. J. Immunol. 2, 349-353
30. Welham, M. J., and Schrader, J. W. (1992) J. Immunol. 149, 2772-2783
31. Dechert, U., Adam, M., Harder, K. W., Clark-Lewis, I., and Jirik, F. (1994) J. Biol. Chem. 269, 5602-5611
32. Otsu, M., Hiles, I., Gout, I., Fry, M. J., Ruiz-Larrea, F., Panayoutou, G., Thompson, A., Dhand, R., Hsuan, J., Totty, N., Smith, A. D., Morgan, S. J., Courtneidge, S. A., Parker, P. J., and Waterfield, M. D. (1991) Cell 65, 91-104
33. Laemlli, U. K. (1970) Nature 227, 680-685
34. Kotanides, H., Moczygemba, M., White, M. F., and Reich, N. C. (1994) J. Biol. Chem. 270, 19481-19486
35. Patti, M-E., Sun, X-J., Bruening, J-C., Araki, E., Lipes, M. A., White, M. F., and Kahn, C. R. (1995) J. Biol. Chem 270 24670-24673
36. Kuhne, M. R., Pawson, T., Lienhard, G. E., and Feng, G.-S. (1993) J. Biol. Chem. 268, 11479-11481